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    AUTOMATIC ANALYER
    141.
    发明申请
    AUTOMATIC ANALYER 有权
    自动分析仪

    公开(公告)号：US20150204794A1

    公开(公告)日：2015-07-23

    申请号：US14413447

    申请日：2013-07-08

    Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

    Inventor： Masahiko Iijima ,  Akihisa Makino ,  Manabu Ando

    IPC: G01N21/75 ,  G01N21/47 ,  G01N1/38 ,  G01N21/59

    CPC classification number: G01N21/75 ,  G01N1/38 ,  G01N21/47 ,  G01N21/59 ,  G01N35/00603 ,  G01N2035/0446 ,  G01N2201/02 ,  G01N2201/061 ,  G01N2201/12

    Abstract: An automatic analyzer which can reduce the effort necessary for conducting a test of limit of detection/limit of quantification properties and managing the test results is provided. Operation condition-setting means for conducting an evaluation test for at least one of a limit of detection and a limit of quantification for each measurement item, determination condition-setting means for setting a determination condition of the evaluation test, and a calculation unit for obtaining a measurement result of a dilution series containing different dilution concentrations by controlling the sample-dispensing mechanism, the reagent-dispensing mechanism and the measurement unit based on the set operation condition, and calculating a test result of the evaluation test from the measurement result of the dilution series based on the set determination condition are disposed.

    Abstract translation: 提供了一种可以减少进行检测限制/限制性能限制和管理测试结果所需的努力的自动分析仪。 用于对每个测量项目进行至少一个检测限和定量限制的评估测试的操作条件设置装置，用于设置评估测试的确定条件的确定条件设置装置，以及用于获得 通过基于设定的操作条件控制样品分注机构，试剂分注机构和测量单元，并根据测定结果计算评价试验的试验结果，对含有不同稀释浓度的稀释系列的测定结果进行计算， 设置基于设定判定条件的稀释系列。

    METHOD AND APPARATUS FOR SEPARATING PLASMA FROM BLOOD FOR BILIRUBIN LEVEL ESTIMATION
    143.
    发明申请
    METHOD AND APPARATUS FOR SEPARATING PLASMA FROM BLOOD FOR BILIRUBIN LEVEL ESTIMATION 审中-公开
    用于从血液分离等离子体水平估计的方法和装置

    公开(公告)号：US20150185233A1

    公开(公告)日：2015-07-02

    申请号：US14418497

    申请日：2013-07-17

    Applicant: KONINKLIJKE PHILIPS N.V.

    Inventor： Anil Shivram Raiker ,  Ravindra Bhat ,  Shrutin Ulman

    IPC: G01N33/72 ,  G01N1/28 ,  G01N21/05 ,  A61B5/15 ,  G01N21/25

    CPC classification number: G01N33/728 ,  A61B5/150022 ,  A61B5/150343 ,  A61B5/150755 ,  B01L3/502753 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2400/0406 ,  B01L2400/0481 ,  G01N1/28 ,  G01N21/05 ,  G01N21/25 ,  G01N33/491 ,  G01N2201/02 ,  G01N2201/061

    Abstract: The present disclosure pertains to a system for separating plasma and/or serum from blood. The system is configured to separate plasma and/or serum from between about 20 and about 50 μl of blood. Separating plasma and/or serum from that amount of blood may be useful during a bilirubin level estimation in newborn babies. The system alleviates the need to centrifuge a sample of blood to separate the blood plasma and/or serum. The system is configured such that the separated serum is held by the system during an optical analysis to estimate bilirubin levels, thus eliminating the need to transfer the serum sample to a cuvette for analysis. In some embodiments, the system comprises a cartridge body, a filter, a serum pathway, an analysis port, a negative pressure source, a suction connector port, and/or other components.

    Abstract translation: 本公开涉及用于从血液中分离血浆和/或血清的系统。 该系统被配置为将血浆和/或血清从约20至约50μl的血液分离。 在新生婴儿的胆红素水平估计中，将血浆和/或血清与该量的血液分离可能是有用的。 该系统减轻了离心血液样品以分离血浆和/或血清的需要。 该系统被配置为使得分离的血清在光学分析期间由系统保持以估计胆红素水平，因此不需要将血清样品转移到比色皿进行分析。 在一些实施例中，该系统包括筒体，过滤器，血清通路，分析端口，负压源，吸入连接器端口和/或其他部件。

    FLOW CELL FOR BIOMATERIAL ANALYSIS AND BIOMATERIAL ANALYSIS DEVICE
    145.
    发明申请
    FLOW CELL FOR BIOMATERIAL ANALYSIS AND BIOMATERIAL ANALYSIS DEVICE 审中-公开
    用于生物体分析和生物物质分析装置的流动细胞

    公开(公告)号：US20150176070A1

    公开(公告)日：2015-06-25

    申请号：US14414235

    申请日：2013-07-11

    Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

    Inventor： Yuichiro Ota ,  Tomohiro Shoji ,  Michiru Fujioka ,  Takanobu Haga

    IPC: C12Q1/68 ,  G01N21/03 ,  G01N15/14 ,  G01N21/64

    CPC classification number: C12Q1/6869 ,  G01N15/1436 ,  G01N15/1459 ,  G01N15/1484 ,  G01N21/0332 ,  G01N21/05 ,  G01N21/6428 ,  G01N21/645 ,  G01N33/5436 ,  G01N2015/0038 ,  G01N2015/1006 ,  G01N2021/6482 ,  G01N2201/0231 ,  G01N2201/061

    Abstract: In a biomaterial analysis, erroneous detection of a particle emitting fluorescence is prevented, and highly sensitive and highly accurate optical detection in biomaterial analysis is performed. A flow cell (104) for biomaterial analysis includes: a light-transmissive upper substrate (310); an antireflective lower substrate (313); and an inner layer section interposed between the upper substrate (310) and the lower substrate (313) and including a flow path (311) in which a particle (312) configured to emit fluorescence is provided. A biomaterial analysis device includes: a flow cell (104) for biomaterial analysis as described above; and an irradiation unit configured to irradiate excitation light; and an optical detection unit (106) configured to detect fluorescence emitted by the particle (312).

    Abstract translation: 在生物材料分析中，防止发射荧光的颗粒的错误检测，并且进行生物材料分析中的高灵敏度和高精度的光学检测。 用于生物材料分析的流动池（104）包括：透光上基板（310）; 抗反射下基板（313）; 以及插入在上基板（310）和下基板（313）之间的内层部分，并且包括设置有发射荧光的颗粒（312）的流路（311）。 生物材料分析装置包括：如上所述的用于生物材料分析的流动池（104）; 以及被配置为照射激发光的照射单元; 以及被配置为检测由所述粒子（312）发射的荧光的光学检测单元（106）。

    MEASUREMENT PROBE AND BIOLOGICAL OPTICAL MEASUREMENT SYSTEM
    146.
    发明申请
    MEASUREMENT PROBE AND BIOLOGICAL OPTICAL MEASUREMENT SYSTEM 审中-公开
    测量探测和生物光学测量系统

    公开(公告)号：US20150164333A1

    公开(公告)日：2015-06-18

    申请号：US14628652

    申请日：2015-02-23

    Applicant: OLYMPUS CORPORATION

    Inventor： Ryosuke ITO ,  Koji MATSUMOTO

    IPC: A61B5/00 ,  G01N21/55 ,  G01N21/47

    CPC classification number: A61B5/0075 ,  A61B1/00165 ,  A61B1/07 ,  A61B5/0084 ,  G01N21/47 ,  G01N21/474 ,  G01N21/49 ,  G01N21/55 ,  G01N2021/4742 ,  G01N2021/557 ,  G01N2201/061 ,  G01N2201/08

    Abstract: A measurement probe is configured to be detachably connected to a biological optical measurement apparatus that performs an optical measurement on body tissue. The measurement probe includes an illumination fiber configured to irradiate the body tissue with illumination light, and a plurality of detection fibers configured to detect return light of at least one of the illumination light reflected from the body tissue and the illumination light scattered from the body tissue. On a plane which is away from distal ends of the illumination fiber and the plurality of detection fibers and through which the illumination light and the return light can pass, a detection area of the return light in each of the plurality of detection fibers is included in all of an illumination area of the illumination fiber or inside of the illumination area.

    Abstract translation: 测量探针被配置为可拆卸地连接到对身体组织进行光学测量的生物学光学测量装置。 测量探头包括被配置为用身体组织照射照明光的照明光纤，以及多个检测光纤，其被配置为检测从身体组织反射的照明光和从身体组织散射的照明光中的至少一个的返回光 。 在远离照明光纤和多个检测光纤的远端并且照明光和返回光可以通过的平面上，多个检测光纤中的每一个中的返回光的检测区域被包括在 照明光纤的所有照明区域或照明区域的内部。

    Particle detectors
    147.
    发明授权
    Particle detectors 有权
    粒子探测器

    公开(公告)号：US09057485B2

    公开(公告)日：2015-06-16

    申请号：US14451330

    申请日：2014-08-04

    Applicant: Xtralis Technologies Ltd

    Inventor： Ron Knox ,  Karl Boettger ,  Kemal Ajay

    IPC: G01N21/00 ,  F21K99/00 ,  G01N21/53 ,  G01N15/02 ,  G01N15/14 ,  G01N15/10

    CPC classification number: G01N21/53 ,  F21K9/00 ,  G01N15/0205 ,  G01N15/10 ,  G01N15/1434 ,  G01N15/1459 ,  G01N21/538 ,  G01N2201/061 ,  G01N2201/062 ,  G01N2201/0621 ,  G01N2201/0627 ,  G01N2201/0633 ,  G01N2201/0696

    Abstract: A beam detector including a light source, a receiver, and a target, acting in cooperation to detect particles in a monitored area. The target reflects incident light, resulting in reflected light being returned to receiver. The receiver is capable of recording and reporting light intensity at a plurality of points across its field of view. In the preferred form the detector emits a first light beam in a first wavelength band; a second light beam in a second wavelength band; and a third light beam in a third wavelength band, wherein the first and second wavelengths bands are substantially equal and are different to the third wavelength band.

    Abstract translation: 一种包括光源，接收器和目标的光束检测器，其协同作用以检测被监视区域中的微粒。 目标反射入射光，导致反射光返回到接收器。 接收机能够在整个视场的多个点上记录和报告光强度。 在优选形式中，检测器发射第一波长带中的第一光束; 在第二波长带中的第二光束; 以及第三波长带中的第三光束，其中所述第一和第二波长带基本相等并且与所述第三波长带不同。

    MULTILAYER STRUCTURE
    149.
    发明申请
    MULTILAYER STRUCTURE 审中-公开
    多层结构

    公开(公告)号：US20150129780A1

    公开(公告)日：2015-05-14

    申请号：US14358614

    申请日：2012-11-13

    Applicant: ARJOWIGGINS SECURITY

    Inventor： Thibault Le Loarer

    IPC: B42D25/333 ,  G01N21/25 ,  G01N21/64

    CPC classification number: B42D25/333 ,  B42D25/00 ,  B42D25/24 ,  B42D25/26 ,  B42D25/29 ,  B42D25/324 ,  B42D25/346 ,  B42D25/382 ,  B42D25/387 ,  B42D25/45 ,  B42D25/455 ,  B42D25/46 ,  B42D25/47 ,  B42D2033/06 ,  B42D2033/22 ,  B42D2033/24 ,  B42D2033/46 ,  B42D2035/24 ,  B42D2035/36 ,  B42D2035/50 ,  D21H21/44 ,  D21H27/32 ,  G01N21/251 ,  G01N21/64 ,  G01N2201/061 ,  G07D7/003 ,  G07D7/20

    Abstract: A multilayer structure contains a first security element, in particular a watermark or pseudo-watermark. A diffusing structure having a diffusing region that at least partially covers the first security element. A first luminescent layer at least partially covers the first security element and is capable of emitting a visible light of a first color when subjected to a predefined excitation radiation. The first luminescent layer extends between the first security element and the diffusing structure or the diffusing structure extends between the first security element and the first luminescent layer. In one variation, the first security element is observable in light transmitted through the multilayer structure when the structure is subjected to a predefined excitation radiation and/or in white light, only from the face of the structure situated on the same side as the first security element.

    Abstract translation: 多层结构包含第一安全元件，特别是水印或伪水印。 一种扩散结构，其具有至少部分地覆盖第一安全元件的扩散区域。 第一发光层至少部分地覆盖第一安全元件，并且当经受预定义的激发辐射时能够发射第一颜色的可见光。 第一发光层在第一安全元件和扩散结构之间延伸，或扩散结构在第一安全元件和第一发光层之间延伸。 在一个变型中，当结构经受预定的激发辐射和/或在白光中时，仅透射通过多层结构的光可观察到第一安全元件，仅从位于与第一安全层相同侧的结构的表面 元件。

    Lamp temperature management systems and methods for liquid chromatography analyzers
    150.
    发明授权
    Lamp temperature management systems and methods for liquid chromatography analyzers 有权
    液相色谱分析仪灯管温度管理系统和方法

    公开(公告)号：US09007595B2

    公开(公告)日：2015-04-14

    申请号：US13781183

    申请日：2013-02-28

    Applicant: PerkinElmer Health Sciences, Inc.

    Inventor： Gregory Hanlon ,  Timothy Neal

    IPC: G01N21/00 ,  G01N21/01 ,  G01J3/10 ,  G01J3/02 ,  G01N30/74

    CPC classification number: G01N30/74 ,  F21V29/67 ,  F21V29/673 ,  F21V29/677 ,  G01J3/0286 ,  G01J3/10 ,  G01N21/01 ,  G01N21/0332 ,  G01N30/8651 ,  G01N2201/061 ,  G01N2201/08

    Abstract: A liquid sample analyzer includes a flow cell, a light source, and a lamp temperature management system. The flow cell is configured to receive a flow of a liquid sample from a liquid sample source. The light source includes a lamp configured to emit light to illuminate the flow of the liquid sample in the flow cell. The lamp temperature management system includes: an air flow generator operable to generate a turbulent air flow to cool the lamp; a thermally conductive primary housing encapsulating the lamp such that a primary air gap is provided between the primary housing and the lamp; and a thermally conductive secondary housing surrounding the primary housing and configured to deflect the turbulent air flow away from the primary housing.

    Abstract translation: 液体样品分析仪包括流动池，光源和灯温度管理系统。 流动池被配置为从液体样品源接收液体样品的流动。 光源包括配置为发射光以照亮流动池中的液体样品的流动的灯。 灯温度管理系统包括：气流发生器，其可操作以产生湍流空气流以冷却灯; 封装灯的导热初级壳体，使得在主壳体和灯之间提供一次气隙; 以及导热次级壳体，其围绕所述主壳体并且构造成使所述紊流空气流偏离所述主壳体。

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