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11.
公开(公告)号:US11773905B2
公开(公告)日:2023-10-03
申请号:US17325946
申请日:2021-05-20
Applicant: FEI Company
Inventor: Pleun Dona , Casper Maria Smit
CPC classification number: F16C33/768 , F16C33/761 , H01J37/15 , H01J2237/1415
Abstract: An axial alignment assembly (100) comprising a first body and a second body. The first body has a substantially cylindrical outer jacket, and has a first alignment axis. The second body comprises a substantially cylindrical inner jacket, and has a second alignment axis. The second body is positioned with respect to said first body in so that said inner jacket faces said outer jacket and in between said inner jacket and said outer jacket a substantially annular recess is formed. The axial alignment assembly further comprises a plurality of resilient elements that are positioned within said annular recess, wherein each resilient element is in contact with said outer jacket of said first body and with said inner jacket of said second body. Each resilient element exerts a force onto said outer jacket and onto said inner jacket for aligning said first alignment axis and said second alignment axis.
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公开(公告)号:US20230162942A1
公开(公告)日:2023-05-25
申请号:US17533610
申请日:2021-11-23
Applicant: FEI Company
Inventor: Pleun Dona , Casper Smit , Rients Jan de Groot
CPC classification number: H01J37/165 , H01J37/18 , B33Y80/00
Abstract: Methods and apparatus are disclosed for providing an X-ray shield within an ultra-high vacuum enclosure. A shell is fabricated, leak-tested, filled with an X-ray shielding material, and sealed. An elongated twisted X-ray shield can be deployed within a pump-out channel of an electron microscope or similar equipment. The shield can incorporate lead within a stainless steel shell, with optional low-Z cladding outside the shell. Further variations are disclosed.
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公开(公告)号:US10921268B1
公开(公告)日:2021-02-16
申请号:US16565058
申请日:2019-09-09
Applicant: FEI Company
Inventor: Bas Hendriksen , Maarten Kuijper , Luigi Mele , Pleun Dona , Erum Raja , Atieh Aminian
IPC: G01N23/225 , G01N1/42 , G01N23/2204
Abstract: Various methods and devices are provided for searching the optimum sample condition of a sample for cryogenic electron microscopy. Multiple samples with different sample conditions may be screened using a sample inspection device. The sample inspection device includes at least a chamber formed between a top electron transparent layer and a bottom electron transparent layer for holding the sample. Multiple pillars are arranged within the chamber. The sample inspection device includes a window covering at least one of the multiple pillars.
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公开(公告)号:US20170032928A1
公开(公告)日:2017-02-02
申请号:US15221510
申请日:2016-07-27
Applicant: FEI Company
Inventor: Luigi Mele , Pleun Dona , Gerard Nicolaas Anne van Veen
CPC classification number: H01J37/20 , B01L3/502723 , B01L2200/0605 , B01L2300/0654 , B01L2300/0887 , B01L2300/123 , B01L2400/0406 , B01L2400/0694 , G01N1/04 , G01N21/03 , G01N21/11 , G01N2021/0346 , G01N2021/6482 , G01N2223/307 , H01J37/26 , H01J2237/2002 , H01J2237/2003 , H01J2237/2005 , H01J2237/2006
Abstract: A micro-chamber for inspecting a sample material immersed in a liquid and a method for filling such a chamber are described. The sample chamber includes an inspection volume for holding the sample material, the inspection volume defined by first and second rigid layers, with a hermetic seal between the layers. The inspection volume within the sample chamber is evacuated. Prior to filling the inspection volume, a thin part of at least one of the rigid layers separates the inspection volume from the outside, the thin part being equipped to be punctured. The liquid with immersed sample material is placed upon the thin part and the thin part is then punctured, resulting in sample material entering the inspection volume.
Abstract translation: 描述了用于检查浸在液体中的样品材料的微室和填充这种室的方法。 样品室包括用于保持样品材料的检查体积,由第一和第二刚性层限定的检查体积,在层之间具有气密密封。 样品室内的检查体积被抽真空。 在填充检查体积之前,至少一个刚性层的薄壁部分将检查体积与外部分开,薄部件被装配成要被刺穿。 将浸有样品的液体放置在薄的部分上,然后将薄的部分穿孔,导致样品进入检查体积。
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15.
公开(公告)号:US08993963B2
公开(公告)日:2015-03-31
申请号:US14325166
申请日:2014-07-07
Applicant: FEI Company
Inventor: Hanno Sebastian von Harrach , Bert Henning Freitag , Pleun Dona
IPC: H01J37/244 , H01J37/26 , H01J49/06 , H01J37/28 , G01N23/225
CPC classification number: H01J37/244 , G01N23/225 , H01J37/26 , H01J37/28 , H01J2237/002 , H01J2237/2442 , H01J2237/28 , H01J2237/2802
Abstract: A detector support for an electron microscope including a detector support ring and flexible elements, wherein a first end of each of the flexible elements is connected to the support ring, and wherein the detector support ring and the flexible elements are configured to support at least two detectors in a circumferential arrangement around an optical axis of the electron microscope such that an optical axis of each of the at least two detectors intersects the optical axis of the electron microscope and a target point of the at least two detectors is maintained relatively constant over a temperature change.
Abstract translation: 一种用于包括检测器支撑环和柔性元件的电子显微镜的检测器支架,其中每个柔性元件的第一端连接到支撑环,并且其中检测器支撑环和柔性元件构造成支撑至少两个 所述检测器围绕所述电子显微镜的光轴围绕圆周布置,使得所述至少两个检测器中的每一个的光轴与所述电子显微镜的光轴相交,并且所述至少两个检测器的目标点保持在相对恒定的 温度变化。
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公开(公告)号:US11915904B2
公开(公告)日:2024-02-27
申请号:US17880624
申请日:2022-08-03
Applicant: FEI Company
Inventor: Alexander Henstra , Pleun Dona
IPC: H01J37/153 , H01J37/28
CPC classification number: H01J37/153 , H01J37/28 , H01J2237/1516 , H01J2237/1534
Abstract: Systems for reducing the generation of thermal magnetic field noise in optical elements of microscope systems, are disclosed. Example microscopy optical elements having reduced Johnson noise generation according to the present disclosure comprises an inner core composed of an electrically isolating material, and an outer coating composed of an electrically conductive material. The product of the thickness of the outer coating and the electrical conductivity is less than 0.01Ω−1. The outer coating causes a reduction in Johnson noise generated by the optical element of greater than 2×, 3×, or an order of magnitude or greater. In a specific example embodiment, the optical element is a corrector system having reduced Johnson noise generation. Such a corrector system comprises an outer magnetic multipole, and an inner electrostatic multipole. The inner electrostatic multipole comprises an inner core composed of an electrically isolating material and an outer coating composed of an electrically conductive material.
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公开(公告)号:US20220392736A1
公开(公告)日:2022-12-08
申请号:US17880624
申请日:2022-08-03
Applicant: FEI Company
Inventor: Alexander Henstra , Pleun Dona
IPC: H01J37/153 , H01J37/28
Abstract: Systems for reducing the generation of thermal magnetic field noise in optical elements of microscope systems, are disclosed. Example microscopy optical elements having reduced Johnson noise generation according to the present disclosure comprises an inner core composed of an electrically isolating material, and an outer coating composed of an electrically conductive material. The product of the thickness of the outer coating and the electrical conductivity is less than 0.01Ω−1. The outer coating causes a reduction in Johnson noise generated by the optical element of greater than 2×, 3×, or an order of magnitude or greater. In a specific example embodiment, the optical element is a corrector system having reduced Johnson noise generation. Such a corrector system comprises an outer magnetic multipole, and an inner electrostatic multipole. The inner electrostatic multipole comprises an inner core composed of an electrically isolating material and an outer coating composed of an electrically conductive material.
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公开(公告)号:US11437216B2
公开(公告)日:2022-09-06
申请号:US17139859
申请日:2020-12-31
Applicant: FEI Company
Inventor: Alexander Henstra , Pleun Dona
IPC: H01J37/153 , H01J37/28
Abstract: Systems for reducing the generation of thermal magnetic field noise in optical elements of microscope systems, are disclosed. Example microscopy optical elements having reduced Johnson noise generation according to the present disclosure comprises an inner core composed of an electrically isolating material, and an outer coating composed of an electrically conductive material. The product of the thickness of the outer coating and the electrical conductivity is less than 0.01Ω−1. The outer coating causes a reduction in Johnson noise generated by the optical element of greater than 2×, 3×, or an order of magnitude or greater. In a specific example embodiment, the optical element is a corrector system having reduced Johnson noise generation. Such a corrector system comprises an outer magnetic multipole, and an inner electrostatic multipole. The inner electrostatic multipole comprises an inner core composed of an electrically isolating material and an outer coating composed of an electrically conductive material.
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公开(公告)号:US11328892B2
公开(公告)日:2022-05-10
申请号:US16987172
申请日:2020-08-06
Applicant: FEI Company
Inventor: Erik Rene Kieft , Pleun Dona , Jasper Frans Mathijs van Rens , Wouter Verhoeven , Peter Mutsaers , Jom Luiten , Ond{hacek over (r)}ej Ba{hacek over (c)}o
Abstract: Disclosed herein are radio frequency (RF) cavities and systems including such RF cavities. The RF cavities are characterized as having an insert with at least one sidewall coated with a material to prevent charge build up without affecting RF input power and that is heat and vacuum compatible. One example RF cavity includes a dielectric insert, the dielectric insert having an opening extending from one side of the dielectric insert to another to form a via, and a coating layer disposed on an inner surface of the dielectric insert, the inner surface facing the via, wherein the coating layer has a thickness and a resistivity, the thickness less than a thickness threshold, and the resistivity greater than a resistivity threshold, wherein the thickness and resistivity thresholds are based partly on operating parameters of the RF cavity.
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公开(公告)号:US20210066032A1
公开(公告)日:2021-03-04
申请号:US16557199
申请日:2019-08-30
Applicant: FEI Company
Inventor: Maarten Kuijper , Ondrej Ludmil Shanel , Mathijs Petrus van den Boogaard , Pleun Dona
Abstract: Cryo compatible sample grids having multi-modal cryo-EM compatible GUIDs, according to the present disclosure include an outer support structure that defines a region of the grid for holding one or more samples, and a plurality of inner support structures that define a plurality of apertures that are each configured to hold a sample. Cryo compatible sample grids further include a first identifier located on the outer support structure, and a second identifier located within the region of the grid for holding the one or more samples. The first identifier is readable with an optical detector, while the second identifier is readable with an electron detector (e.g., within an electron microscope). Specifically, the second identifier is readable with an electron detector when one or more teeth and/or holes that comprise the second identifier are filled with ice from a vitrification process.
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