公开(公告)号：US08111395B2

公开(公告)日：2012-02-07

申请号：US12006677

申请日：2008-01-04

Applicant: E. Neil Lewis

Inventor： E. Neil Lewis

IPC: G01J3/28

CPC classification number: G01J3/02 ,  G01J3/021 ,  G01J3/0289 ,  G01J3/2823 ,  G01N15/1475 ,  G01N2015/1486 ,  G01N2015/1497

Abstract: In one general aspect, a spectroscopic apparatus is disclosed for investigating heterogeneity of a sample area. The apparatus includes an image acquisition system operative to acquire images of a plurality of sub-areas in the sample area and a sub-area selection interface operative to receive a selection designating one of the sub-areas for which an image has been obtained. A spectrometer has a field of view and is operative to acquire a spectrum of at least part of one of the sub-areas in its field of view, and a positioning mechanism is responsive to the sub-area selection interface and operative to position the field of view of the spectrometer relative to the sample area based on a received selection.

Abstract translation: 在一般的方面，公开了一种用于调查样品区域的异质性的分光装置。 所述装置包括：图像采集系统，用于采集所述采样区域中的多个子区域的图像;以及子区域选择接口，用于接收指定已获得图像的子区域之一的选择。 光谱仪具有视场，并且可操作以在其视野中获取一个子区域的至少一部分的光谱，并且定位机构响应于子区域选择界面并且可操作地定位场 基于接收到的选择，相对于样品区域的光谱仪的视图。

公开(公告)号：US20110205536A1

公开(公告)日：2011-08-25

申请号：US12994091

申请日：2009-05-21

Applicant: Geir Johnsen

Inventor： Geir Johnsen

IPC: G01J3/42

CPC classification number: G01N21/255 ,  G01J3/0208 ,  G01J3/027 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/06 ,  G01J3/10 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01N2201/0218 ,  G01S17/89 ,  G02B21/33

Abstract: An apparatus for placement on or in a body of water for hyperspectral imaging of material in the water comprises an artificial light source and a hyperspectral imager. These are arranged so that in use light exits the apparatus beneath the surface of the water and is reflected by said material before re-entering the apparatus beneath the surface of the water and entering the hyperspectral imager. The hyperspectral imager is adapted to produce hyperspectral image data having at least two spatial dimensions.

Abstract translation: 用于放置在水中或在水中的装置用于水中材料的高光谱成像包括人造光源和高光谱成像器。 这些布置使得在使用中，光从水表面下方离开设备，并且在重新进入设备在水面下方并进入高光谱成像器之前被所述材料反射。 高光谱成像器适于产生具有至少两个空间维度的高光谱图像数据。

公开(公告)号：US07953572B2

公开(公告)日：2011-05-31

申请号：US11904392

申请日：2007-09-27

Applicant: Toru Kobayashi ,  Masao Nakamuro

Inventor： Toru Kobayashi ,  Masao Nakamuro

IPC: G06F15/00

CPC classification number: G01B11/24 ,  G01J3/02 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/504 ,  G01N33/32

Abstract: A measurement system for obtaining a predetermined estimated value, including a measuring section for acquiring measurement data with respect to a measurement object, a display section for displaying indication concerning a measurement, a display controller, a measurement controller, a storing section for storing the measurement data, a computing section for obtaining the estimated value based on the measurement data, and a checking section for checking whether a required number of measurement data has been acquired. The display controller causes the display section to display first information relating to measurement elements required for acquiring the measurement data, and second information, for allowing an operator to recognize whether the measurement has been completed. The measurement controller causes the selection information to function as a site for accepting a command indicating start of the measurement of the measurement element relating to the individual selection information.

Abstract translation: 一种用于获得预定估计值的测量系统，包括用于获取关于测量对象的测量数据的测量部分，用于显示关于测量的指示的显示部分，显示控制器，测量控制器，用于存储测量的存储部分 数据，用于基于测量数据获得估计值的计算部分，以及用于检查是否已经获取了所需数量的测量数据的检查部分。 显示控制器使显示部显示与获取测量数据所需的测量元件有关的第一信息，以及第二信息，用于允许操作者识别测量是否已经完成。 测量控制器使得选择信息用作用于接受指示与各个选择信息相关的测量元素的测量开始的命令的站点。

公开(公告)号：US07907780B2

公开(公告)日：2011-03-15

申请号：US12543769

申请日：2009-08-19

Applicant: Christopher H. Pearson ,  Gary N. Bodnar ,  Karl F. Seibert ,  Ronald J. Duke

Inventor： Christopher H. Pearson ,  Gary N. Bodnar ,  Karl F. Seibert ,  Ronald J. Duke

IPC: G06K9/46

CPC classification number: G01J3/2803 ,  G01J1/0233 ,  G01J3/02 ,  G01J3/0262 ,  G01J3/0272 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/50 ,  G01J3/524 ,  H04N5/2351

Abstract: A method for providing an intensity or brightness measurement using a digital image-capturing device comprising: selecting a target area within a field of view of the image-capturing device, the target area containing pixels; measuring the intensity or brightness of pixels in a target area; accumulating the intensity or brightness values of the pixels in the target area; and determining a pixel value representative of the intensity or brightness of the pixels in the target area. A device for making color measurements comprising an image-capture device, a processor or logic device, and a memory location for accumulating color data, and the processor or logic device is programmed to perform color measurements by accumulating the data for pixels located in the target area in memory, and determining a representative color value.

Abstract translation: 一种用于使用数字图像捕获装置提供强度或亮度测量的方法，包括：选择所述图像捕获装置的视野内的目标区域，所述目标区域包含像素; 测量目标区域中像素的强度或亮度; 累积目标区域中的像素的强度或亮度值; 以及确定表示所述目标区域中的像素的强度或亮度的像素值。 一种用于进行颜色测量的设备，包括图像捕获设备，处理器或逻辑设备以及用于累积颜色数据的存储器位置，并且处理器或逻辑设备被编程为通过对位于目标中的像素累积数据来执行颜色测量 存储器中的区域，并且确定代表性颜色值。

公开(公告)号：US20110038832A1

公开(公告)日：2011-02-17

申请号：US12857473

申请日：2010-08-16

Applicant: Jerome B. ZELDIS

Inventor： Jerome B. ZELDIS

IPC: A61K31/4035 ,  A61K39/395 ,  A61K38/21 ,  A61K31/454 ,  A61K38/17 ,  A61K31/522 ,  A61K38/27 ,  A61K31/56 ,  A61P27/02

CPC classification number: A61K38/185 ,  A61K31/454 ,  A61K31/522 ,  A61K31/545 ,  A61K31/557 ,  A61K31/56 ,  A61K38/21 ,  A61K38/27 ,  G01J3/0208 ,  G01J3/0286 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/501 ,  G01J3/524 ,  Y10S514/912 ,  A61K2300/00

Abstract: Provided herein are methods of treating macular degeneration, which comprises administering to a patient in need thereof a therapeutically effective amount of (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, or a pharmaceutically acceptable salt or solvate thereof.

Abstract translation: 本文提供治疗黄斑变性的方法，其包括向有需要的患者施用治疗有效量的（+） - 2- [1-（3-乙氧基-4-甲氧基苯基）-2-甲基磺酰基乙基] -4-乙酰氨基异吲哚啉 -1,3-二酮，或其药学上可接受的盐或溶剂化物。

公开(公告)号：US20100328954A1

公开(公告)日：2010-12-30

申请号：US12880818

申请日：2010-09-13

Applicant: Andrew Bodkin

Inventor： Andrew Bodkin

IPC: F21V17/02 ,  F21S6/00 ,  F21V7/00

CPC classification number: G02B26/02 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/027 ,  G01J3/0278 ,  G01J3/0289 ,  G01J3/36 ,  G01J5/06 ,  G01J5/602 ,  G01J2005/0077 ,  G01S7/4812 ,  G01S17/87 ,  G01S17/89 ,  G02B3/0006 ,  G02B17/0808 ,  G02B17/0852 ,  G02B17/0896 ,  G02B23/12 ,  G02B26/0816 ,  G02B26/0875 ,  H04N5/33 ,  H04N5/332

Abstract: A shutter includes micro-optics having first and second concentrator arrays. A transducer laterally displaces one of the first and second concentrator arrays between transmissive and shuttered modes. In the transmissive mode, the arrays of concentrators are optically aligned to permit electromagnetic energy passing through the first array of concentrators to pass through the second array of concentrators. In the shuttered mode, the electromagnetic radiation is blocked from passing through the second array of concentrators. The concentrators may be compound parabolic concentrators, or lenslets positioned on opposing plates with pinholes printed therethrough. The shutter may increase f-number of radiation passing therethrough, and may be used in a limited f-cone radiation source with shuttering abilities, for example reducing f-cone of radiation output from the radiation source.

Abstract translation: 快门包括具有第一和第二集中器阵列的微光学器件。 换能器在透射和快门模式之间横向移位第一和第二聚光器阵列中的一个。 在透射模式中，聚光器阵列被光学对准以允许通过第一集中器阵列的电磁能量穿过第二阵列的聚光器。 在快门模式中，电磁辐射被阻止通过第二阵列的聚光器。 集中器可以是复合抛物面聚光器，或者位于相对的板上的小透镜，其中针孔印刷在其中。 快门可以增加通过其中的f数量的辐射，并且可以用于具有快门能力的有限的f-锥体辐射源，例如减小从辐射源输出的辐射的f锥。

公开(公告)号：US20100315629A1

公开(公告)日：2010-12-16

申请号：US12724192

申请日：2010-03-15

Applicant: Kevin J. Knopp ,  Robert L. Green ,  Brendon D. Tower ,  Christopher D. Brown ,  Gregory H. Vander Rhodes

Inventor： Kevin J. Knopp ,  Robert L. Green ,  Brendon D. Tower ,  Christopher D. Brown ,  Gregory H. Vander Rhodes

IPC: G01J3/44 ,  G01J3/00 ,  G01N21/62 ,  G01N21/55 ,  G01N21/47 ,  G01N21/59

CPC classification number: G01N21/17 ,  G01J3/02 ,  G01J3/0232 ,  G01J3/0262 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/42 ,  G01J3/44 ,  G01J3/4412 ,  G01N21/47 ,  G01N21/4738 ,  G01N21/55 ,  G01N21/59 ,  G01N21/65 ,  G01N2021/3595 ,  G01N2201/0221 ,  G01N2201/0612 ,  G01N2201/062 ,  G01N2201/105 ,  G01N2201/125

Abstract: Disclosed are apparatus, kits, methods, and systems that include a radiation source configured to direct radiation to a sample; a detector configured to measure radiation from the sample; an electronic processor configured to determine infotmation about the sample based on the measured radiation; a housing enclosing the source, the detector, and the electronic processor, the housing having a hand-held form factor; an arm configured to maintain a separation between the sample and the housing, the arm including a first end configured to connect to the housing and a second end configured to contact the sample; and a layer positioned on the second end of the arm, the layer being configured to contact the sample and to transmit at least a portion of the radiation from the sample to the detector.

Abstract translation: 公开了包括被配置为将辐射引导到样品的辐射源的装置，试剂盒，方法和系统; 检测器，被配置为测量来自样品的辐射; 配置为基于所测量的辐射来确定关于样本的信息的电子处理器; 包围所述源，所述检测器和所述电子处理器的外壳，所述外壳具有手持外形尺寸; 臂被配置为保持样品和壳体之间的分离，所述臂包括构造成连接到壳体的第一端和被配置为接触样品的第二端; 以及位于所述臂的第二端上的层，所述层被配置为接触所述样品并将所述辐射的至少一部分从所述样品透射到所述检测器。

公开(公告)号：US07840380B2

公开(公告)日：2010-11-23

申请号：US12039947

申请日：2008-02-29

Applicant: Roger D. Bernhardt

Inventor： Roger D. Bernhardt

IPC: G21C17/00 ,  G01J1/00 ,  G01J3/10

CPC classification number: G01N21/31 ,  G01J3/02 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0289 ,  G01J3/10 ,  G01J3/42 ,  G01N2021/1795 ,  G01N2201/0214 ,  G01N2201/0627 ,  G01N2201/0696 ,  G01S7/003 ,  G01S7/497 ,  G01S17/003 ,  G01S17/89 ,  G01S17/95 ,  G05D1/104 ,  Y02A90/19

Abstract: A method for mapping, in three dimensions, the contents of a plume within an area is described. The method includes distributing spectrally sensitive sensors on a first surface of a vehicle, distributing spectrally sensitive emitters on a second surface of a vehicle, causing the emitters to output a signal directed through the plume and towards the sensors, receiving at least a portion of the emitter output at the sensors, communicating an output of the sensors, the sensor output caused by the received optical emitter output, to a central processing unit, and analyzing the sensor outputs and time-based vehicle positions to characterize the plume and an area surrounding the plume in three dimensions over a period of time.

Abstract translation: 描述了在三维中映射区域内的羽流的内容的方法。 该方法包括在车辆的第一表面上分布频谱敏感的传感器，在车辆的第二表面上分配频谱敏感的发射器，使得发射器输出引导通过羽流并朝向传感器的信号，接收至少一部分 在传感器处输出发射器，将传感器的输出，由接收到的光发射器输出引起的传感器输出传送到中央处理单元，以及分析传感器输出和基于时间的车辆位置，以表征羽流和周围的区域 在一段时间内三维羽流。

公开(公告)号：US20100265502A1

公开(公告)日：2010-10-21

申请号：US12759082

申请日：2010-04-13

Applicant: Matthew Nelson ,  Patrick Treado ,  Ryan Priore

Inventor： Matthew Nelson ,  Patrick Treado ,  Ryan Priore

IPC: G01J3/30

CPC classification number: G01J3/36 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/027 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/2823 ,  G01N21/31 ,  G01N2201/0833 ,  G01N2201/0846

Abstract: System and method for spatially and spectrally parallelized FAST. A sample is illuminated to thereby produce interacted photons. The photons are passed through a filter and received at a two-dimensional end of a FAST device wherein said FAST device comprises a two-dimensional array of optical fibers drawn into a one-dimensional fiber stack so as to effectively convert a two-dimensional array of optical fibers into a curvilinear field of view, and wherein said two-dimensional array of optical fibers is configured to receive said photons and transfer said photons out of said fiber array spectral translator device and to a spectrograph through said one-dimensional fiber stack wherein said one-dimensional fiber stack comprises at least two columns of fibers spatially offset in parallel at the entrance slit of said spectrograph. The photons are then detected at a detector to thereby obtain a spectroscopic data set representative of the sample.

Abstract translation: 用于空间和光谱平行化FAST的系统和方法。 照射样品从而产生相互作用的光子。 光子通过过滤器并在FAST装置的二维端接收，其中所述FAST装置包括被拉入一维纤维堆叠的二维光纤阵列，以有效地将二维阵列 的光纤变成曲线视场，并且其中所述二维光纤阵列被配置为接收所述光子并将所述光子从所述光纤阵列光谱转换器装置传送到通过所述一维光纤堆的光谱仪，其中 所述一维纤维堆叠包括在所述光谱仪的入口狭缝处空间上平行偏移的至少两列纤维。 然后在检测器处检测光子，从而获得代表样品的光谱数据集。

公开(公告)号：US07817268B2

公开(公告)日：2010-10-19

申请号：US11574161

申请日：2005-08-24

Applicant: Bernardus Leonardus Gerardus Bakker ,  Michael Cornelis Van Beek ,  Gérald Lucassen ,  Marjolein Van Der Voort ,  Wouter Harry Jacinth Rensen

Inventor： Bernardus Leonardus Gerardus Bakker ,  Michael Cornelis Van Beek ,  Gérald Lucassen ,  Marjolein Van Der Voort ,  Wouter Harry Jacinth Rensen

IPC: G01J3/30

CPC classification number: G01J3/02 ,  G01J1/4228 ,  G01J3/0229 ,  G01J3/0289

Abstract: The present invention provides a spectroscopic system as well as a method of autonomous tuning of a spectroscopic system and a corresponding computer program product. By detecting the position of return radiation in a transverse plane of an aperture of a spectroscopic analysis unit, a control signal can be generated that allows to drive servo driven translation or tilting stages of optical components. In this way a transverse misalignment of a spectroscopic system can be effectively detected. Generally, a plurality of different detection schemes are realizable allowing for an autonomous tuning of the spectroscopic system and for autonomous elimination of misalignment of a spectroscopic system.

Abstract translation: 本发明提供一种光谱系统以及自动调谐光谱系统和相应的计算机程序产品的方法。 通过检测光谱分析单元的孔径的横向平面中的返回辐射的位置，可以产生允许驱动光学部件的伺服驱动的平移或倾斜级的控制信号。 以这种方式，可以有效地检测光谱系统的横向偏移。 通常，多个不同的检测方案是可实现的，允许分光系统的自主调谐并且用于自动消除光谱系统的未对准。