公开(公告)号：US11852537B2

公开(公告)日：2023-12-26

申请号：US18130867

申请日：2023-04-04

Applicant: MIFTEK CORPORATION

Inventor： Masanobu Yamamoto ,  Keegan Hernandez ,  J. Paul Robinson ,  John Jaiber González Murillo

IPC: G01J3/02 ,  G01J3/44

CPC classification number: G01J3/4406 ,  G01J3/0218 ,  G01J3/0227

Abstract: A flow cytometry measurement system is disclosed which includes a flow chamber configured to flow particles of interest in a flow stream, one or more optical sources configured to excite the particles of interest by an excitation light activated and deactivated according to a pulse train thus causing particles of interest emitting emission light, one or more sensor packages each comprising a plurality of photodetectors configured to receive emission light from the particles of interest and, in response, provide an output voltage signal and an output current signal corresponding to photoelectron response of an incident photon on the one or more sensor packages, and a detector configured to determine successive single molecular decay of the particles of interest, generate an emission pulse associated with each incident photon on the one or more sensor packages, and count the number of emission pulses.

公开(公告)号：US11846545B2

公开(公告)日：2023-12-19

申请号：US17288035

申请日：2019-10-22

Applicant: Specto S.r.L. ,  Fondazione Istituto Italiano di Tecnologia

Inventor： Giuseppe Antonacci

IPC: G01J3/44 ,  G01J3/02 ,  G01N21/63

CPC classification number: G01J3/4412 ,  G01J3/0218 ,  G01N2021/638

Abstract: Spectrometer for analyzing the spectrum of a Brillouin scattered light including input means receiving the scattered light, and selecting means for selecting and separating specific multiple frequency components of the scattered light. The selecting means has at least one main input, and at least an optical detector is coupled to the selecting means for measuring the intensity of the different frequency components and reconstructing the spectrum profile of the scattered light. The selecting means include an optical integrated circuit having at least one optical ring resonator of a first type having an input waveguide for receiving the light from the input means, a closed loop waveguide having an effective refractive index neff, and an output waveguide. The selecting means further have at least a modulator element of the effective refractive index neff coupled to the closed loop waveguide of the optical ring resonator of the first type.

公开(公告)号：US11838060B2

公开(公告)日：2023-12-05

申请号：US17502848

申请日：2021-10-15

Applicant: Cisco Technology, Inc.

Inventor： Joel Richard Goergen ,  Charles Calvin Byers ,  Robert Gregory Twiss ,  D. Brice Achkir ,  Chad M. Jones

IPC: H04B10/80 ,  G02B6/42 ,  H04L12/40 ,  H04M19/08 ,  H04L12/12 ,  H04L12/10 ,  H02J50/80 ,  H02J50/30 ,  G02B6/38 ,  H02S40/38 ,  G01J3/02

CPC classification number: H04B10/807 ,  G02B6/4293 ,  H02J50/30 ,  H02J50/80 ,  H04L12/10 ,  H04L12/12 ,  H04L12/40045 ,  H04L12/40091 ,  H04L12/40176 ,  H04M19/08 ,  G01J3/0218 ,  G02B6/3817 ,  H02S40/38

Abstract: In one embodiment, a method includes receiving power delivered over a data fiber cable at an optical transceiver installed at a network communications device and transmitting data and the power from the optical transceiver to the network communications device. The network communications device is powered by the power received from the optical transceiver. An apparatus is also disclosed herein.

公开(公告)号：US20230333054A1

公开(公告)日：2023-10-19

申请号：US18098060

申请日：2023-01-17

Applicant: Life Technologies Corporation

Inventor： Shaohong Wang

IPC: G01N27/447 ,  G01J3/02 ,  G01J3/18 ,  G01J3/44

CPC classification number: G01N27/44721 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0289 ,  G01J3/0294 ,  G01J3/18 ,  G01J3/4406 ,  G01N27/44791

Abstract: A system for separating biological molecules includes a plurality of capillaries, a capillary mount, a plurality of optical fibers, a fiber mount, an optical detector, and a motion stage. The plurality of capillaries are configured to separate biological molecules in a sample. Each capillary comprising a detection portion configured to pass electromagnetic radiation into the capillary. The plurality of capillaries are coupled to the capillary mount such that the detection portions are fixedly located relative to one another. Each optical fiber includes a receiving end to receive emissions. The optical fibers are coupled to the fiber mount such that the receiving ends of the optical fibers are fixedly located relative to one another. The optical detector is configured to produce an alignment signal. The motion stage is configured to align the receiving ends of the optical fibers to the detection portions based on values of the alignment signal.

公开(公告)号：US20230314223A1

公开(公告)日：2023-10-05

申请号：US17997205

申请日：2021-03-31

Applicant: WUHAN JINGCE ELECTRONIC GROUP CO., LTD ,  WUHAN JINGLI ELECTRONIC TECHNOLOGY CO., LTD

Inventor： Changdong Ou ,  Zengqiang Zheng ,  Shiwen Luo ,  Zhikun Hong ,  Zhou Wang ,  Fan Zhong ,  Luning Liu ,  Xiaofan Feng ,  Ronghua Liu ,  Yafei Shen ,  Kai Chen

IPC: G01J3/50 ,  G09G3/32 ,  G01J3/02 ,  G01J3/28

CPC classification number: G01J3/506 ,  G09G3/32 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/2823 ,  G09G2300/026 ,  G09G2320/0693 ,  G01J2003/2866

Abstract: A chromaticity measurement method and device for calibration of a tiled LED display screen (A) having the advantages of convenience in operation and accurate measurement. The chromaticity measurement method includes: imaging emergent light from the tiled LED display screen (A) with an objective lens (1); receiving a light beam from the objective lens (1) with a transflective lens (2) and performing beam splitting to obtain a first light beam and a second light beam; receiving the first light beam with an imaging sensor (3) to obtain an original image; receiving the second light beam in a two-dimensional lattice form with a movable optical fiber array coupling device (4), and converting the second light beam into one-dimensional lattice light; and obtaining chromaticity information and spectrum information of a plurality of regions on the tiled LED display screen (A) according to the one-dimensional lattice light with a spectrum acquisition device (5). The emergent light is split, analysis is performed with the imaging sensor (3), chromaticity measurement and spectrum measurement are performed with a spectrometer (52), and calibration and correction are performed on the imaging sensor (3) on the basis of measurement results of the spectrometer (52).

公开(公告)号：US20230288313A1

公开(公告)日：2023-09-14

申请号：US18319048

申请日：2023-05-17

Applicant: Cytek Biosciences, Inc.

Inventor： Ming Yan ,  Yung-Chieh Hsieh ,  David Vrane ,  Eric Chase

IPC: G01N15/14 ,  G01J1/08 ,  G01N21/47 ,  G01J3/02 ,  G01J3/36

CPC classification number: G01N15/1436 ,  G01J1/08 ,  G01N21/47 ,  G01N15/1459 ,  G01N15/1434 ,  G01J3/0218 ,  G01J3/0291 ,  G01J3/0256 ,  G01J3/36 ,  G01J3/021 ,  G01J3/0208 ,  G01N2015/145 ,  G01N2015/1006

Abstract: A method includes launching, from an optical fiber, fluorescent light of differing wavelengths generated by different fluorochromes attached to particles in a sample fluid; magnifying an image size from an end of the optical fiber to a first dichroic filter of a row of a plurality of dichroic filters in a de-multiplexing imaging array; alternatively reflecting the fluorescent light between the plurality of dichroic filters and a plurality of micro-mirrors to collimate the fluorescent light on odd numbered dichroic filters and re-image the fluorescent light on even numbered dichroic filters; band passing different wavelength ranges of the fluorescent light at each of the plurality of dichroic filters to de-multiplex the wavelength spectrum of the wavelength range of the fluorescent light; and detecting fluorescent light in each of the different wavelength ranges to count a number of each of the different particles in the sample fluid.

公开(公告)号：US20230288254A1

公开(公告)日：2023-09-14

申请号：US18301871

申请日：2023-04-17

Applicant: II-VI Delaware, Inc.

Inventor： Michael John Laurence Cahill ,  Yang Li

IPC: G01J3/02 ,  H04B10/25 ,  G01J3/45

CPC classification number: G01J3/0297 ,  H04B10/25 ,  G01J3/0218 ,  G01J3/0286 ,  G01J3/45

Abstract: Described herein is a wavelength reference device comprising a housing defining an internal environment having a known temperature. A broadband optical source is disposed within the housing and configured to emit an optical signal along an optical path. The optical signal has optical power within a wavelength band of interest. An optical etalon is also disposed within the housing and positioned in the optical path to filter the optical signal to define a filtered optical signal that includes one or more reference spectral features having a known wavelength at the known temperature. The device also includes an optical output for outputting the filtered optical signal.

公开(公告)号：US11740128B2

公开(公告)日：2023-08-29

申请号：US16927804

申请日：2020-07-13

Applicant: Sanguis Corporation

Inventor： Jeffrey Owen Katz

IPC: G01J3/02 ,  G01J3/44 ,  G01N21/65 ,  G01J3/06 ,  G01N33/49

CPC classification number: G01J3/4412 ,  G01J3/021 ,  G01J3/0202 ,  G01J3/0218 ,  G01J3/0275 ,  G01J3/06 ,  G01N21/65 ,  G01N33/492 ,  G01J2003/062 ,  G01J2003/064

Abstract: A system for non-invasively interrogating an in vivo sample for measurement of analytes comprises a pulse sensor coupled to the in vivo sample for detect a blood pulse of the sample and for generating a corresponding pulse signal, a laser generator for generating a laser radiation having a wavelength, power and diameter, the laser radiation being directed toward the sample to elicit Raman signals, a laser controller adapted to activate the laser generator, a spectrometer situated to receive the Raman signals and to generate analyte spectral data; and a computing device coupled to the pulse sensor, laser controller and spectrometer which is adapted to correlate the spectral data with the pulse signal based on timing data received from the laser controller in order to isolate spectral components from analytes within the blood of the sample from spectral components from analytes arising from non-blood components of the sample.

公开(公告)号：US20230266170A1

公开(公告)日：2023-08-24

申请号：US18017812

申请日：2021-07-26

Applicant: CytoVeris Inc.

Inventor： Alan Kersey ,  David Fournier ,  Rishikesh Pandey ,  Gary Root

IPC: G01J3/44 ,  G01J3/12 ,  G01J3/02 ,  G01J3/08 ,  G01J3/10

CPC classification number: G01J3/44 ,  G01J3/12 ,  G01J3/0208 ,  G01J3/08 ,  G01J3/10 ,  G01J3/0218 ,  G01J2003/102 ,  G01J2003/1213 ,  G01N21/65

Abstract: A system and method for analyzing a sample using Raman spectral light includes a light source, a light detector, a narrow band pass filter and an analyzer. Within the system, excitation light is directed to interrogate the sample. The narrow band pass filter is positioned to receive Raman scattered light produced as a result of the interrogation. The light detector is positioned to receive the Raman scattered light that has passed through the at least one narrow band pass filter. The analyzer contains stored instructions that when executed cause the processor to a) control the light source; and b) process signals produced by the light detector to analyze the sample material, the signals representative of the intensity of the Raman scattered light received by the at least one light detector corresponding to one or more wavenumbers in a high wavenumber region of a Raman signal.

公开(公告)号：US11735401B2

公开(公告)日：2023-08-22

申请号：US17466912

申请日：2021-09-03

Applicant: Applied Materials, Inc.

Inventor： Chuang-Chia Lin ,  Upendra Ummethala ,  Steven E. Babayan ,  Lei Lian

IPC: G01J3/443 ,  G01J3/02 ,  H01J37/32 ,  H01J37/22

CPC classification number: H01J37/32917 ,  G01J3/0218 ,  G01J3/443 ,  H01J37/22 ,  H01J2237/24585

Abstract: Embodiments disclosed herein include optical sensor systems and methods of using such systems. In an embodiment, the optical sensor system comprises a housing and an optical path through the housing. In an embodiment, the optical path comprises a first end and a second end. In an embodiment a reflector is at the first end of the optical path, and a lens is between the reflector and the second end of the optical path. In an embodiment, the optical sensor further comprises an opening through the housing between the lens and the reflector.