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公开(公告)号:US20230296434A1
公开(公告)日:2023-09-21
申请号:US18147682
申请日:2022-12-28
Applicant: NOVA LTD.
Inventor: Gilad BARAK , Yonatan OREN
CPC classification number: G01J3/0208 , G01J3/0224 , G01J3/06 , G01J3/10 , G01J3/2803 , G01J3/2823 , G01J3/44 , G01J2003/283
Abstract: A polarized Raman Spectrometric system for defining parameters of a polycrystalline material, said system comprising: a polarized Raman Spectrometric apparatus, a computer-controlled sample stage for positioning a sample at different locations, and a computer comprising a processor and an associated memory.
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32.
公开(公告)号:US20230288313A1
公开(公告)日:2023-09-14
申请号:US18319048
申请日:2023-05-17
Applicant: Cytek Biosciences, Inc.
Inventor: Ming Yan , Yung-Chieh Hsieh , David Vrane , Eric Chase
CPC classification number: G01N15/1436 , G01J1/08 , G01N21/47 , G01N15/1459 , G01N15/1434 , G01J3/0218 , G01J3/0291 , G01J3/0256 , G01J3/36 , G01J3/021 , G01J3/0208 , G01N2015/145 , G01N2015/1006
Abstract: A method includes launching, from an optical fiber, fluorescent light of differing wavelengths generated by different fluorochromes attached to particles in a sample fluid; magnifying an image size from an end of the optical fiber to a first dichroic filter of a row of a plurality of dichroic filters in a de-multiplexing imaging array; alternatively reflecting the fluorescent light between the plurality of dichroic filters and a plurality of micro-mirrors to collimate the fluorescent light on odd numbered dichroic filters and re-image the fluorescent light on even numbered dichroic filters; band passing different wavelength ranges of the fluorescent light at each of the plurality of dichroic filters to de-multiplex the wavelength spectrum of the wavelength range of the fluorescent light; and detecting fluorescent light in each of the different wavelength ranges to count a number of each of the different particles in the sample fluid.
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公开(公告)号:US11747204B2
公开(公告)日:2023-09-05
申请号:US17394143
申请日:2021-08-04
Applicant: The Johns Hopkins University
Inventor: Scott M. Hendrickson , Jeremiah J. Wathen , Michael J. Fitch , David W. Blodgett , Vincent R. Pagan
CPC classification number: G01J3/4338 , G01J3/0208 , G01J3/0264 , G01J3/2823 , G02B3/04 , G01J2003/4332
Abstract: A system includes first and second radiation sources, first and second detectors, a signal digitizer, a controller, and an analyzer. The first and second radiation sources generate respective first and second beams of radiation to irradiate a target. The first beam and second beams each include a first wavelength operated at a first modulation frequency and a second wavelength operated at a second modulation frequency. The first and second detectors each include a photo-sensitive element that generate first or second detection signals, a Faraday shielding enclosure, a signal amplifier, and a frequency mixer to frequency-adjust the first or second detection signals. The controller provides timing information to inform an activation scheme of the first and second radiation sources and corresponding radiation detection events at the first and second detectors. The analyzer analyzes the first and second detection signals and determines at least amplitude and phase information of the scattered radiation.
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34.
公开(公告)号:US20230266170A1
公开(公告)日:2023-08-24
申请号:US18017812
申请日:2021-07-26
Applicant: CytoVeris Inc.
Inventor: Alan Kersey , David Fournier , Rishikesh Pandey , Gary Root
CPC classification number: G01J3/44 , G01J3/12 , G01J3/0208 , G01J3/08 , G01J3/10 , G01J3/0218 , G01J2003/102 , G01J2003/1213 , G01N21/65
Abstract: A system and method for analyzing a sample using Raman spectral light includes a light source, a light detector, a narrow band pass filter and an analyzer. Within the system, excitation light is directed to interrogate the sample. The narrow band pass filter is positioned to receive Raman scattered light produced as a result of the interrogation. The light detector is positioned to receive the Raman scattered light that has passed through the at least one narrow band pass filter. The analyzer contains stored instructions that when executed cause the processor to a) control the light source; and b) process signals produced by the light detector to analyze the sample material, the signals representative of the intensity of the Raman scattered light received by the at least one light detector corresponding to one or more wavenumbers in a high wavenumber region of a Raman signal.
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公开(公告)号:US11731171B2
公开(公告)日:2023-08-22
申请号:US16611992
申请日:2018-05-09
Applicant: 6511660 CANADA INC.
Inventor: Julien Neige , Nathanaël Lortie , Alain Brasseur
CPC classification number: B07C5/342 , G01J3/0208 , G01J3/108 , G01J3/42
Abstract: Spectral identification and optical sorting systems and methods are disclosed. The system can include a conveying roller having a conveying surface on its outer lateral periphery along which a flow of objects can be transported; an illumination unit to illuminate the objects on the conveying surface; a spectral detector to detect object light from the objects and output spectral data; and a processor to derive, from the measured spectral data, material-specific information associated with the objects. A sorting unit can be provided to sort the objects based on the material-specific information. An infrared emitter-detector assembly for measuring a mid-wavelength infrared (MWIR) response of an object is also disclosed and includes an illumination unit having a blackbody-like source operated at a temperature of about at least 2000 kelvins; and a MWIR detector having a detection waveband including wavelengths between about 2.5 and 8 micrometers to detect object light from the object.
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公开(公告)号:US11731129B2
公开(公告)日:2023-08-22
申请号:US17357372
申请日:2021-06-24
Applicant: BERKELEY LIGHTS, INC.
Inventor: Paul M. Lundquist , Paul M. Lebel , Phillip Ronald Thomas Jess
IPC: B01L3/00 , B01L7/00 , G01J3/02 , G01J3/10 , G01J3/44 , G01N21/31 , G01N21/64 , G02B21/06 , G02B21/16 , G02B21/36 , G01N1/40
CPC classification number: B01L3/502715 , B01L7/00 , G01J3/0208 , G01J3/0229 , G01J3/10 , G01J3/4406 , G01N1/40 , G01N21/31 , G01N21/6458 , G02B21/06 , G02B21/16 , G02B21/361 , B01L2200/147 , B01L2300/046 , B01L2300/0645 , B01L2300/0654 , B01L2300/0663 , B01L2300/0883 , B01L2300/1822 , B01L2400/0424
Abstract: The present disclosure relates to an optical apparatus for imaging and/or manipulating micro-objects in a microfluidic device, such as a light-actuated microfluidic (LAMF) device, and related systems and methods. The optical apparatus can comprise a structured light modulator, a first and a second tube lens, an objective lens, a dichroic beam splitter, and an image sensor. The structured light modulator can be configured to receive unstructured light beams and transmit structured light beams for illuminating micro-objects located within an enclosure of the microfluidic device and/or selectively activating one or more of a plurality of dielectrophoresis (DEP) electrodes of the microfluidic device. The image light beams received by the image sensor can be used to form an image of at least a portion of the microfluidic device.
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公开(公告)号:US11725989B2
公开(公告)日:2023-08-15
申请号:US16283888
申请日:2019-02-25
Applicant: Green Vision Systems Ltd.
Inventor: Danny S. Moshe
CPC classification number: G01J3/45 , B81B7/02 , G01B9/02049 , G01J3/0208 , G01J3/0256 , G01J3/4535 , G02B26/06 , G02B7/182
Abstract: A microelectromechanical system (MEMS) (10), and a microelectromechanical (MEM) optical interferometer (18), for hyper-spectral imaging and analysis. System (10) includes matrix configured collimating micro lens (16), for receiving and collimating electromagnetic radiation (60) emitted by objects (12) in a scene or sample (14); microelectromechanical optical interferometer (18), for forming divided collimated object emission beam (72) having an optical path difference, and for generating an interference image exiting optical interferometer (18); matrix configured focusing micro lens (20); micro detector (22), for detecting and recording generated interference images; and micro central programming and signal processing unit (24). Applicable for on-line (e.g., real time or near-real time) or off-line hyper-spectral imaging and analyzing, on a miniaturized or ‘micro’ (sub-centimeter [1 cm (10 mm) or less], or sub-millimeter) scale, essentially any types or kinds of biological, physical, or/and chemical, (i.e., biophysicochemical) objects.
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公开(公告)号:US20230224446A1
公开(公告)日:2023-07-13
申请号:US18054801
申请日:2022-11-11
Applicant: ALIGN TECHNOLOGY, INC.
Inventor: Noam BABAYOFF
IPC: H04N13/15 , H04N13/257 , A61C9/00 , A61B1/06 , G01J3/02 , A61B1/00 , G01J3/10 , G01B11/24 , A61B5/00 , G01N21/25 , G01B11/25 , A61B1/247 , G06T7/90 , H01L27/148 , A61B1/24 , G01J3/50 , A61C19/04 , G06T7/00 , A61B5/107 , H04N13/296 , H04N13/207 , G06T7/12 , H04N13/271 , G01J3/51 , G01J3/46
CPC classification number: H04N13/15 , A61B1/00009 , A61B1/24 , A61B1/00096 , A61B1/247 , A61B1/0615 , A61B1/0638 , A61B1/0646 , A61B1/0676 , A61B1/0684 , A61B5/0068 , A61B5/0088 , A61B5/1077 , A61B5/1079 , A61C9/0053 , A61C9/0066 , A61C19/04 , G01B11/24 , G01B11/25 , G01J3/02 , G01J3/10 , G01J3/50 , G01J3/0205 , G01J3/0208 , G01J3/0216 , G01J3/0218 , G01J3/0224 , G01J3/0243 , G01J3/0256 , G01J3/501 , G01J3/508 , G01N21/255 , G06T7/0012 , G06T7/12 , G06T7/90 , H01L27/14868 , H04N13/207 , H04N13/257 , H04N13/271 , H04N13/296 , G01J3/51 , G01J3/462 , G06T2207/10024 , G06T2207/10028 , G06T2207/30036
Abstract: A device for determining the surface topology and associated color of a structure, such as a teeth segment, includes a scanner for providing depth data for points along a two-dimensional array substantially orthogonal to the depth direction, and an image acquisition means for providing color data for each of the points of the array, while the spatial disposition of the device with respect to the structure is maintained substantially unchanged. A processor combines the color data and depth data for each point in the array, thereby providing a three-dimensional color virtual model of the surface of the structure. A corresponding method for determining the surface topology and associate color of a structure is also provided.
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公开(公告)号:US11698304B2
公开(公告)日:2023-07-11
申请号:US16451901
申请日:2019-06-25
Applicant: Wayne State University
Inventor: Gregory William Auner , Michelle Ann Brusatori , Changhe Huang
CPC classification number: G01J3/44 , G01J3/0208 , G01J3/1838 , G01J3/2803 , G01N21/03 , G01J2003/1861
Abstract: Apparatuses, systems, and methods for Raman spectroscopy are described. In certain implementations, a spectrometer is provided. The spectrometer may include a plurality of optical elements, comprising an entrance aperture, a collimating element, a volume phase holographic grating, a focusing element, and a detector array. The plurality of optical elements are configured to transfer the light beam from the entrance aperture to the detector array with a high transfer efficiency over a preselected spectral band.
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公开(公告)号:US20230204423A1
公开(公告)日:2023-06-29
申请号:US18179117
申请日:2023-03-06
Applicant: Artilux, Inc.
Inventor: Chih-Wei Yeh , Hung-Chih Chang , Yun-Chung Na , Tsung-Ting Wu , Shu-Lu Chen
CPC classification number: G01J3/50 , G01B11/24 , G01J3/0208 , G01J3/51
Abstract: Systems, apparatuses, and methods for multi-application optical sensing are provided. For example, an optical sensing apparatus can include a photodetector array, a first circuitry, and a second circuitry. The photodetector array includes a plurality of photodetectors, wherein a first subset of the plurality of photodetectors are configured as a first region for detecting a first optical signal, and a second subset of the plurality of photodetectors are configured as a second region for detecting a second optical signal. The first circuitry, coupled to the first region, is configured to perform a first function based on the first optical signal to output a first output result. The second circuitry, coupled to the second region, is configured to perform a second function based on the second optical signal to output a second output result.
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