公开(公告)号：US07760353B2

公开(公告)日：2010-07-20

申请号：US12248344

申请日：2008-10-09

Applicant: John Maier ,  Jeffrey Cohen

Inventor： John Maier ,  Jeffrey Cohen

IPC: G01J3/44

CPC classification number: G01N21/65 ,  G01J3/02 ,  G01J3/0227 ,  G01J3/0291 ,  G01J3/44 ,  G01N21/658 ,  G01N2021/656 ,  G01N2201/129

Abstract: A spectroscopic method and system to identify a biofilm of a microorganism. A sample containing a sample microorganism is irradiated with substantially monochromatic radiation. A Raman data set is obtained based on radiation scattered from the irradiated sample. A database is searched in accordance with the Raman data set in order to identify a known Raman data set from the database. The database contains a plurality of known Raman data sets where each known Raman data set is associated with a known sessile form of a corresponding known microorganism. A sessile form of the sample microorganism is identified based on the known Raman data set identified by the searching.

Abstract translation: 鉴定微生物生物膜的光谱方法和系统。 用基本上单色的辐射照射含有样品微生物的样品。 基于从照射样品散射的辐射获得拉曼数据集。 根据拉曼数据集搜索数据库，以便从数据库中识别已知的拉曼数据集。 数据库包含多个已知的拉曼数据集，其中每个已知的拉曼数据集与相应的已知微生物的已知无形形式相关联。 基于通过搜索识别的已知拉曼数据集来鉴定样品微生物的固定形式。

公开(公告)号：US20090251694A1

公开(公告)日：2009-10-08

申请号：US12485023

申请日：2009-06-15

Applicant: Kevin J. Knopp ,  Peidong Wang ,  Masud Azimi ,  Daryoosh Vakhshoori

Inventor： Kevin J. Knopp ,  Peidong Wang ,  Masud Azimi ,  Daryoosh Vakhshoori

IPC: G01J3/44

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/0232 ,  G01J3/0272 ,  G01J3/0291 ,  G01J3/44 ,  G01J2003/1213 ,  G01N21/65 ,  G01N2021/656

Abstract: A Raman probe system includes: a base station; a mobile robot remotely controllable from the base station; a Raman probe assembly supported by the robot, the Raman probe assembly including a laser and a spectrometer; a camera supported by the robot; and a communication subsystem operable to communicate images from the camera and results from the Raman probe assembly to the base station. In some embodiments, a Raman probe system includes: a mobile robot remotely controllable from a base station, the robot including a body and an articulated arm; a camera supported by the robot; a Raman probe assembly supported by the robot, the optical control assembly mounted on the body of the robot; and an optical probe mounted on the articulated arm of the robot; and a wireless communication system operable to communicate images from the camera and results from the Raman probe assembly to the base station.

Abstract translation: 拉曼探针系统包括：基站; 从基站远程控制的移动机器人; 由机器人支撑的拉曼探针组件，拉曼探针组件包括激光器和光谱仪; 由机器人支持的相机; 以及通信子系统，其可操作以将来自相机的图像和来自拉曼探针组件的结果传送到基站。 在一些实施例中，拉曼探针系统包括：从基站远程控制的移动机器人，所述机器人包括主体和铰接臂; 由机器人支持的相机; 由机器人支撑的拉曼探针组件，安装在机器人主体上的光学控制组件; 以及安装在机器人的铰接臂上的光学探针; 以及无线通信系统，其可操作以将来自相机的图像和来自拉曼探针组件的结果传送到基站。

公开(公告)号：US07548313B2

公开(公告)日：2009-06-16

申请号：US11497893

申请日：2006-08-02

Applicant: Quang-Viet Nguyen

Inventor： Quang-Viet Nguyen

IPC: G01J3/28

CPC classification number: G01J3/44 ,  B33Y80/00 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0227 ,  G01J3/0262 ,  G01J3/26

Abstract: A compact and robust imaging Raman spectrograph has a collimating input lens assembly, a spectral filter assembly, a transmission diffraction grating, a focusing lens assembly, and a light detector. The spectral filter assembly is located between the two lenses and comprises a notch or long-pass filter optical interference filter, a plurality of optical channel plates for limiting the optical acceptance angle of the light passing the optical interference filter, and a transmission diffraction grating, all mounted in a single assembly. The spectral filter assembly permits a very high degree of elastically scattered light rejection and excellent stray-light reduction and management, while permitting a high level of optical throughput to maximize the signal of the weakly scattered Raman signal.

Abstract translation: 紧凑且鲁棒的成像拉曼光谱仪具有准直输入透镜组件，光谱滤光器组件，透射衍射光栅，聚焦透镜组件和光检测器。 光谱滤波器组件位于两个透镜之间，并且包括凹口或长通滤波器光学干涉滤光器，用于限制通过光学干涉滤光器的光的光学接受角度的多个光学通道板，以及透射衍射光栅， 全部安装在单个组件中。 频谱滤波器组件允许非常高程度的弹性散射光抑制和优异的散射光减少和管理，同时允许高水平的光学吞吐量以使弱散射拉曼信号的信号最大化。

公开(公告)号：US20090073421A1

公开(公告)日：2009-03-19

申请号：US12217506

申请日：2008-07-03

Applicant: Wayne D. Jung ,  Bussell W. Jung ,  Alen R. Loudermilk

Inventor： Wayne D. Jung ,  Bussell W. Jung ,  Alen R. Loudermilk

IPC: G01N21/00 ,  G06F15/00 ,  G01J3/46

CPC classification number: G01J3/02 ,  G01J1/0411 ,  G01J1/0437 ,  G01J1/0474 ,  G01J1/06 ,  G01J1/44 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/0229 ,  G01J3/0251 ,  G01J3/0259 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0275 ,  G01J3/0278 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/2803 ,  G01J3/46 ,  G01J3/463 ,  G01J3/508 ,  G01J3/51 ,  G01J3/513

Abstract: Optical characteristic measuring systems and methods such as for determining the color or other optical characteristics of teeth are disclosed. Perimeter receiver fiber optics preferably are spaced apart from a source fiber optic and receive light from the surface of the object/tooth being measured. Light from the perimeter fiber optics pass to a variety of filters. The system utilizes the perimeter receiver fiber optics to determine information regarding the height and angle of the probe with respect to the object/tooth being measured. Under processor control, the optical characteristics measurement may be made at a predetermined height and angle. Various color spectral photometer arrangements are disclosed. Translucency, fluorescence, gloss and/or surface texture data also may be obtained. Audio feedback may be provided to guide operator use of the system. The probe may have a removable or shielded tip for contamination prevention. A method of producing dental prostheses based on measured data also is disclosed. Measured data also may be stored and/or organized as part of a patient data base. Such methods and implements may be desirably utilized for purposes of detecting and preventing counterfeiting or the like.

公开(公告)号：US07505129B2

公开(公告)日：2009-03-17

申请号：US11473949

申请日：2006-06-23

Applicant: David Geoffrey Marrow ,  Blu Eric Englehorn ,  David A. Yahn

Inventor： David Geoffrey Marrow ,  Blu Eric Englehorn ,  David A. Yahn

IPC: G01J3/44

CPC classification number: C08F10/00 ,  B01J19/0006 ,  B01J2208/00964 ,  C08F210/16 ,  C08F2400/02 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/44 ,  G01N21/65 ,  C08F2/00 ,  C08F2/06

Abstract: Methods and systems for analysis of the polymerization material of solution polymerization processes are provided. In certain embodiments, the methods and systems subject the polymerization material to Raman spectroscopy analysis. The Raman spectroscopy provides analysis of reaction mixtures and/or product streams in solution polymerization processes. The Raman spectroscopy analysis may include both compositional and characterization analysis of the reaction mixtures and product streams. The spectroscopy results can be used to provide process control feedback to adjust operating parameters of the reactor operations and/or an associated polymerization product handling and finishing processes.

Abstract translation: 提供了用于分析溶液聚合方法的聚合材料的方法和系统。 在某些实施方案中，方法和系统使聚合材料进行拉曼光谱分析。 拉曼光谱提供了溶液聚合过程中反应混合物和/或产物流的分析。 拉曼光谱分析可以包括反应混合物和产物流的组成和表征分析。 光谱分析结果可用于提供过程控制反馈以调节反应器操作的操作参数和/或相关联的聚合产物处理和整理过程。

公开(公告)号：US20090033928A1

公开(公告)日：2009-02-05

申请号：US11894887

申请日：2007-08-22

Applicant: Masud Azimi ,  Kevin J. Knopp ,  Steve McLaughlin

Inventor： Masud Azimi ,  Kevin J. Knopp ,  Steve McLaughlin

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/024 ,  G01J3/0291 ,  G01N21/65 ,  G01N2021/656 ,  G01N2201/08

Abstract: A Raman spectrometry assembly includes a Raman spectrometer having a laser light source and a Raman signal analyzer, an interface module comprising a housing which is connectable to and disconnectable from the spectrometer, and a fiber optic assembly which is connectable to and disconnectable from the interface module, the fiber optic assembly including optical fibers and a probe head at a distal end thereof for disposition adjacent a specimen to be tested, the optical fibers extending from the probe head and adapted to extend to the interface module.

Abstract translation: 拉曼光谱仪组件包括具有激光光源和拉曼信号分析器的拉曼光谱仪，包括可与光谱仪连接并可与光谱仪分离的外壳的接口模块，以及可与接口模块连接并与其分离的光纤组件 ，所述光纤组件包括光纤和在其远端处的探针头，用于邻近待测试的样品布置，所述光纤从探头延伸并适于延伸到接口模块。

公开(公告)号：US07474396B2

公开(公告)日：2009-01-06

申请号：US11257073

申请日：2006-01-17

Applicant: Wei Wu ,  Zhiyong Li ,  Shih-Yuan Wang

Inventor： Wei Wu ,  Zhiyong Li ,  Shih-Yuan Wang

IPC: G01J3/44 ,  G01J3/00

CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/0227 ,  G01J3/0256 ,  G01J3/18 ,  G01N21/65 ,  G01N21/658 ,  G02B5/1809

Abstract: A Raman spectroscopy system is disclosed which includes a sub-wavelength resonant grating filter and a photodiode with integrated sub-wavelength resonant grating filter are disclosed. The resonant grating filter comprises an array of diffraction elements having a periodic spacing that is less than the wavelength of radiation to be filtered and which are formed over a waveguide layer. The filter, which can reject a specific wavelength of radiation, can be placed between a Raman sample and a Raman detector in order to filter radiation that is elastically scattered from the sample while transmitting other wavelengths. The wavelength rejected by the filter can be selected by tilting the filter with respect to the radiation incident upon the filter.

Abstract translation: 公开了一种拉曼光谱系统，其包括亚波长谐振光栅滤光器和具有集成子波长谐振光栅滤光器的光电二极管。 谐振光栅滤波器包括衍射元件的阵列，其具有小于待滤波的辐射的波长并且在波导层上形成的周期性间隔。 可以将能够抑制特定波长的辐射的滤光器放置在拉曼样品和拉曼检测器之间，以便过滤从样品弹性散射的辐射，同时传输其他波长。 可以通过使过滤器相对于入射到过滤器上的辐射倾斜来选择由过滤器拒绝的波长。

公开(公告)号：US07403285B2

公开(公告)日：2008-07-22

申请号：US11085934

申请日：2005-03-21

Applicant: Wayne D Jung ,  Russell W. Jung ,  Alan R. Loudermilk

Inventor： Wayne D Jung ,  Russell W. Jung ,  Alan R. Loudermilk

IPC: G01J3/28

CPC classification number: G01J3/51 ,  A61B5/0088 ,  A61B2560/0233 ,  A61B2562/247 ,  A61C19/10 ,  G01J1/04 ,  G01J1/0411 ,  G01J1/0437 ,  G01J1/0474 ,  G01J1/06 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/0229 ,  G01J3/0251 ,  G01J3/0259 ,  G01J3/0264 ,  G01J3/0278 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/508 ,  G01J3/513 ,  G01N21/474 ,  G01N21/57 ,  G06F19/00 ,  G07D7/1205 ,  G07D7/17

Abstract: A method for determining spectral characteristics of an object is disclosed. A probe is positioned in proximity relative to the object. The probe provides light from at least first and second light sources positioned first and second distances from a central light receiver. The first light source and the central light receiver define a first critical height from the surface below which no specularly reflected light from the first light source is received by the central light receiver, and the second light source and the central light receiver define a second critical height from the surface below which no specularly reflected light from the second light source is received by the central light receiver. The first critical height is different from the second critical height.

Abstract translation: 公开了一种用于确定物体的光谱特征的方法。 探头位于相对于物体的邻近位置。 探针提供来自位于距离中央光接收器的第一和第二距离的至少第一和第二光源的光。 第一光源和中央光接收器限定了第一临界高度，在该第一临界高度之下，来自第一光源的镜面反射光不被中央光接收器接收，并且第二光源和中心光接收器限定第二临界高度 没有来自第二光源的镜面反射光的表面的高度被中央光接收器接收。 第一临界高度与第二临界高度不同。

公开(公告)号：US20080030728A1

公开(公告)日：2008-02-07

申请号：US11497893

申请日：2006-08-02

Applicant: Quang-Viet Nguyen

Inventor： Quang-Viet Nguyen

IPC: G01J3/28

CPC classification number: G01J3/44 ,  B33Y80/00 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0227 ,  G01J3/0262 ,  G01J3/26

Abstract: A compact and robust imaging Raman spectrograph has a collimating input lens assembly, a spectral filter assembly, a transmission diffraction grating, a focusing lens assembly, and a light detector. The spectral filter assembly is located between the two lenses and comprises a notch or long-pass filter optical interference filter, a plurality of optical channel plates for limiting the optical acceptance angle of the light passing the optical interference filter, and a transmission diffraction grating, all mounted in a single assembly. The spectral filter assembly permits a very high degree of elastically scattered light rejection and excellent stray-light reduction and management, while permitting a high level of optical throughput to maximize the signal of the weakly scattered Raman signal.

Abstract translation: 紧凑且鲁棒的成像拉曼光谱仪具有准直输入透镜组件，光谱滤光器组件，透射衍射光栅，聚焦透镜组件和光检测器。 光谱滤波器组件位于两个透镜之间，并且包括凹口或长通滤波器光学干涉滤光器，用于限制通过光学干涉滤光器的光的光学接受角度的多个光学通道板，以及透射衍射光栅， 全部安装在单个组件中。 频谱滤波器组件允许非常高程度的弹性散射光抑制和优异的散射光减少和管理，同时允许高水平的光学吞吐量以使弱散射拉曼信号的信号最大化。

公开(公告)号：US20070165214A1

公开(公告)日：2007-07-19

申请号：US11257073

申请日：2006-01-17

Applicant: Wei Wu ,  Zhiyong Li ,  Shih-Yuan Wang

Inventor： Wei Wu ,  Zhiyong Li ,  Shih-Yuan Wang

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/0227 ,  G01J3/0256 ,  G01J3/18 ,  G01N21/65 ,  G01N21/658 ,  G02B5/1809

Abstract: A Raman spectroscopy system is disclosed which includes a sub-wavelength resonant grating filter and a photodiode with integrated sub-wavelength resonant grating filter are disclosed. The resonant grating filter comprises an array of diffraction elements having a periodic spacing that is less than the wavelength of radiation to be filtered and which are formed over a waveguide layer. The filter, which can reject a specific wavelength of radiation, can be placed between a Raman sample and a Raman detector in order to filter radiation that is elastically scattered from the sample while transmitting other wavelengths. The wavelength rejected by the filter can be selected by tilting the filter with respect to the radiation incident upon the filter.

Abstract translation: 公开了一种拉曼光谱系统，其包括亚波长谐振光栅滤波器和具有集成子波长谐振光栅滤波器的光电二极管。 谐振光栅滤波器包括衍射元件的阵列，其具有小于待滤波的辐射的波长并且在波导层上形成的周期间隔。 可以将能够抑制特定波长的辐射的滤光器放置在拉曼样品和拉曼检测器之间，以便过滤从样品弹性散射的辐射，同时传输其他波长。 可以通过使过滤器相对于入射到过滤器上的辐射倾斜来选择由过滤器拒绝的波长。