公开(公告)号：US20230266170A1

公开(公告)日：2023-08-24

申请号：US18017812

申请日：2021-07-26

Applicant: CytoVeris Inc.

Inventor： Alan Kersey ,  David Fournier ,  Rishikesh Pandey ,  Gary Root

IPC: G01J3/44 ,  G01J3/12 ,  G01J3/02 ,  G01J3/08 ,  G01J3/10

CPC classification number: G01J3/44 ,  G01J3/12 ,  G01J3/0208 ,  G01J3/08 ,  G01J3/10 ,  G01J3/0218 ,  G01J2003/102 ,  G01J2003/1213 ,  G01N21/65

Abstract: A system and method for analyzing a sample using Raman spectral light includes a light source, a light detector, a narrow band pass filter and an analyzer. Within the system, excitation light is directed to interrogate the sample. The narrow band pass filter is positioned to receive Raman scattered light produced as a result of the interrogation. The light detector is positioned to receive the Raman scattered light that has passed through the at least one narrow band pass filter. The analyzer contains stored instructions that when executed cause the processor to a) control the light source; and b) process signals produced by the light detector to analyze the sample material, the signals representative of the intensity of the Raman scattered light received by the at least one light detector corresponding to one or more wavenumbers in a high wavenumber region of a Raman signal.

公开(公告)号：US11576579B2

公开(公告)日：2023-02-14

申请号：US16004661

申请日：2018-06-11

Applicant: Boston Scientific Scimed, Inc.

Inventor： George Wilfred Duval

IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/024 ,  A61B5/026 ,  A61B5/1455 ,  G01J3/10 ,  G01J3/28 ,  G01J3/08 ,  G01J3/42 ,  A61B5/021 ,  A61B5/08

Abstract: Embodiments herein relate to reflective optical medical sensor devices. In an embodiment, a reflective optical medical sensor device including a central optical detector and a plurality of light emitter units disposed around the central optical detector is provided. A plurality of peripheral optical detectors can be disposed to the outside of the plurality of light emitter units. Each of the plurality of peripheral optical detectors can form a channel pair with one of the plurality of light emitter units. The reflective optical medical sensor device can also include a controller in electrical communication with the central optical detector, the light emitter units, and the peripheral optical detectors. The controller can be configured to measure performance of channel pairs; select a particular channel pair; and measure a physiological parameter using the selected channel pair. Other embodiments are also included herein.

公开(公告)号：US11346774B2

公开(公告)日：2022-05-31

申请号：US16344183

申请日：2017-10-27

Applicant: United Kingdom Research and Innovation

Inventor： Damien Weidmann

IPC: G01N21/3504 ,  G01J3/08 ,  G01J3/42 ,  G01N21/27

Abstract: Methods and apparatus are disclosed for detecting one or more species in a sample, wherein laser probe light is frequency swept across at least one infra red absorption spectrum feature of each of the species. A path from the probe light source to a single detector element may be switched between at least one sample absorption cell or volume and one or more reference cells or volumes.

公开(公告)号：US20210369119A1

公开(公告)日：2021-12-02

申请号：US16949466

申请日：2020-10-30

Applicant: Colgate-Palmolive Company

Inventor： Deborah Ann Peru ,  Hrebesh Molly Subhash

IPC: A61B5/00 ,  G01J3/02 ,  G02B6/04 ,  G01J3/06 ,  A61B5/145 ,  A61B5/1455 ,  G01J3/08 ,  G01J3/10 ,  G01N21/25 ,  G01J3/18 ,  G01J3/36 ,  G01N21/31 ,  G01J3/32

Abstract: A spectroscopic system may include: a probe having a probe tip and an optical coupler, the optical coupler including an emitting fiber group and first and second receiving fiber groups, each fiber group having a first end and a second end, wherein the first ends of the fiber groups are formed into a bundle and optically exposed through the probe tip; a light source optically coupled to the second end of the emitting fiber group, the light source emitting light in at least a first waveband and a second waveband, the second waveband being different from the first waveband; a first spectrometer optically coupled to the second end of the first receiving fiber group and configured to process light in the first waveband; and a second spectrometer optically coupled to the second end of the second receiving fiber group and configured to process light in the second waveband.

公开(公告)号：US10473584B2

公开(公告)日：2019-11-12

申请号：US15985032

申请日：2018-05-21

Applicant: PerkinElmer Singapore PTE Ltd.

Inventor： Ralph Lance Carter ,  Robert Alan Hoult

IPC: G01N21/35 ,  G01J3/08 ,  G01J3/02 ,  G01J3/453 ,  G01N21/47

Abstract: Diffuse reflectance spectroscopy apparatus for use in analyzing a sample comprising a sample receiving location 2 for receiving a sample 3 for analysis; an illumination arrangement 4 for directing light towards a received sample; a detector 6 for detecting light reflected by a received sample; and collection optics 5 for directing light reflected by a received sample towards the detector. The illumination arrangement further comprises an interferometer 42 and a half beam block 45a, 45b which is disposed substantially at a focus in the optical path for blocking light which exits the interferometer, passes said focus, and is reflected from re-entering the interferometer. A half beam block 45a may be disposed in the optical path between the interferometer and the light source 41 for blocking light that exits the interferometer back towards the light source and is reflected by the light source from re-entering the interferometer and/or a half beam block 45b may be disposed in the optical path on the opposite side of the interferometer than the light source.

公开(公告)号：US20180266942A1

公开(公告)日：2018-09-20

申请号：US15985032

申请日：2018-05-21

Applicant: PerkinElmer Singapore PTE Ltd.

Inventor： Ralph Lance Carter ,  Robert Alan Hoult

IPC: G01N21/35 ,  G01J3/08 ,  G01J3/02 ,  G01J3/453 ,  G01N21/47

CPC classification number: G01N21/35 ,  G01J3/021 ,  G01J3/0262 ,  G01J3/0291 ,  G01J3/0297 ,  G01J3/08 ,  G01J3/453 ,  G01J2003/4534 ,  G01N21/4738 ,  G01N2021/3595 ,  G01N2201/061 ,  G01N2201/068

Abstract: Diffuse reflectance spectroscopy apparatus for use in analysing a sample comprising a sample receiving location 2 for receiving a sample 3 for analysis; an illumination arrangement 4 for directing light towards a received sample; a detector 6 for detecting light reflected by a received sample; and collection optics 5 for directing light reflected by a received sample towards the detector. The illumination arrangement further comprises an interferometer 42 and a half beam block 45a, 45b which is disposed substantially at a focus in the optical path for blocking light which exits the interferometer, passes said focus, and is reflected from re-entering the interferometer. A half beam block 45a may be disposed in the optical path between the interferometer and the light source 41 for blocking light that exits the interferometer back towards the light source and is reflected by the light source from re-entering the interferometer and/or a half beam block 45b may be disposed in the optical path on the opposite side of the interferometer than the light source.

公开(公告)号：US09228898B2

公开(公告)日：2016-01-05

申请号：US14008964

申请日：2012-03-27

Applicant: Sepehr Kiani ,  Peter Lewis Stokes ,  David H. Tracy

Inventor： Sepehr Kiani ,  Peter Lewis Stokes ,  David H. Tracy

IPC: G01J3/28 ,  G01J3/42 ,  G01J3/02 ,  G01J3/06 ,  G01N21/64 ,  G01N15/14 ,  G01J3/44 ,  G01J3/08 ,  G01J3/10 ,  G01J3/14 ,  G01J3/18

CPC classification number: G01J3/42 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0216 ,  G01J3/0248 ,  G01J3/0291 ,  G01J3/06 ,  G01J3/08 ,  G01J3/10 ,  G01J3/14 ,  G01J3/18 ,  G01J3/2803 ,  G01J3/44 ,  G01J3/4406 ,  G01N15/1434 ,  G01N15/1459 ,  G01N15/1484 ,  G01N21/6456

Abstract: The present invention generally pertains to a system, method and kit for the detection and measurement of spectroscopic properties of light from a sample, or the scalable detection and measurement of spectroscopic properties of light from each sample present among multiple samples, simultaneously, wherein the system comprises: an optical train comprising a dispersing element; and an image sensor. The light detected and measured may comprise light scattered from a sample, emitted as chemiluminescence by a chemical process within a sample, selectively absorbed by a sample, or emitted as fluorescence from a sample following excitation.

Abstract translation: 本发明一般涉及一种用于检测和测量来自样品的光的光谱特性的系统，方法和试剂盒，或同时进行多个样品中存在的每个样品的光的光谱特性的可伸缩检测和测量，其中系统 包括：包括分散元件的光学系列; 和图像传感器。 检测和测量的光可以包括从样品散射的光，通过样品内的化学过程作为化学发光发射，被样品选择性吸收，或者在激发后作为荧光从样品中发射。

公开(公告)号：US09128037B2

公开(公告)日：2015-09-08

申请号：US14293473

申请日：2014-06-02

Applicant: SICK AG

Inventor： Rolf Disch ,  Florian Bruchig ,  Pascal Ortwein

IPC: G01N21/01 ,  G01N21/33 ,  G01N21/35 ,  G01J3/427 ,  G01N21/31 ,  G01N21/3504 ,  G01J3/08 ,  G01J3/10 ,  G01J3/42

CPC classification number: G01N21/3151 ,  G01J3/08 ,  G01J3/10 ,  G01J3/42 ,  G01J3/427 ,  G01N21/33 ,  G01N21/3504 ,  G01N2021/3155 ,  G01N2021/317 ,  G01N2021/3513

Abstract: The invention relates to a measurement apparatus for the determination of gas concentrations. The apparatus comprises two spectral channels, wherein the channels are separated by a single chopper wheel. The chopper wheel has several functions. On the transmitting side, it brings the light of the two light sources on the same measuring path, on the receiving side it associates the light to the associated receiver; it has its chopper function to use the lock-in technique; and it opens the possibility to implement an easy zero point correction.

Abstract translation: 本发明涉及一种用于确定气体浓度的测量装置。 该装置包括两个光谱通道，其中通道由单个切碎机轮分开。 斩波轮有几个功能。 在发射侧，它将两个光源的光引入相同的测量路径，在接收侧，它将光与相关的接收器相关联; 它具有切割功能，可以使用锁定技术; 并且打开了实现简单零点校正的可能性。

公开(公告)号：US08975594B2

公开(公告)日：2015-03-10

申请号：US13673045

申请日：2012-11-09

Applicant: GE Aviation Systems LLC

Inventor： Thomas Baby Sebastian ,  Sarah Christine Maas Stotz ,  Eric Daniel Buehler ,  Benjamin Thomas Occhipinti

IPC: G01J3/36 ,  G01N21/25 ,  G01J3/02 ,  G01J3/08 ,  G01J3/26 ,  G01J3/28 ,  H04N5/33 ,  G02B27/10 ,  G02B26/08

CPC classification number: G01N21/255 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/0237 ,  G01J3/0256 ,  G01J3/0294 ,  G01J3/08 ,  G01J3/26 ,  G01J3/2823 ,  G01J3/36 ,  G01J2003/2826 ,  G02B26/0816 ,  G02B27/1013 ,  H04N5/2254 ,  H04N5/332

Abstract: A multispectral staring array comprises, amongst other things, at least two sensors where each sensor is adapted to detect an image in a different predetermined spectral sensitivity; a first lens to focus capture spectral bands; a spectral filter between the lens and the sensors to subdivide the incident spectral bands; and a second lens to direct and focus the subdivided incident spectral bands on each of the sensors.

Abstract translation: 多光谱凝视阵列尤其包括至少两个传感器，其中每个传感器适于检测不同预定光谱灵敏度的图像; 聚焦捕获光谱带的第一透镜; 透镜和传感器之间的光谱滤波器，用于细分入射光谱带; 以及第二透镜，用于引导和聚焦每个传感器上的细分入射光谱带。

公开(公告)号：US08520308B2

公开(公告)日：2013-08-27

申请号：US13267825

申请日：2011-10-06

Applicant: John Gunderson

Inventor： John Gunderson

IPC: G02B27/14 ,  F42B15/01 ,  G01J3/08

CPC classification number: G02B27/144 ,  F41G7/226 ,  F41G7/2293 ,  G01S7/4816 ,  G01S17/66

Abstract: A system and method of reducing turbulence sensitivity in a laser spot detector. Embodiments may include using beam splitters, reflectors, and beam deviators. The reflectors may be trihedral reflectors and the beam deviators may be segmented wedge plates having predetermined physical angles and angle directions in each wedge segment designed to produce opposing blurs for each segment of the aperture. A predetermined blur introduced into each line of sight eliminates the need for de-focus, thereby mitigating effects such as centroid shift caused by turbulence or dirty/damaged sensor apertures.

Abstract translation: 一种降低激光光斑检测器中湍流灵敏度的系统和方法。 实施例可以包括使用分束器，反射器和光束偏移器。 反射器可以是三面体反射器，并且光束偏移器可以是在每个楔形段中具有预定物理角度和角度方向的分段楔形板，其被设计成为孔的每个部分产生相反的模糊。 在每个视线中引入的预定模糊消除了对焦的需要，从而减轻诸如由湍流或脏/损坏的传感器孔引起的重心移动的影响。