公开(公告)号：US09164032B2

公开(公告)日：2015-10-20

申请号：US14108986

申请日：2013-12-17

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01N21/35 ,  G01N21/359 ,  A61B5/1455 ,  G01J3/453 ,  A61B5/00 ,  H01S3/30 ,  G01J3/14 ,  G01J3/18 ,  G01J3/28

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A system and method for using near-infrared or short-wave infrared (SWIR) light sources for identification of counterfeit drugs may perform spectroscopy using a super-continuum laser to provide detection in a non-contact and non-destructive manner at stand-off or remote distances with minimal sample preparation. Also, near-infrared or SWIR light may penetrate through plastic containers and packaging, permitting on-line inspection and rapid scanning. The near-infrared or SWIR spectroscopy may also be used to detect illicit drugs and their chemical composition. Moreover, the spectroscopic techniques may also be applied to quality assessment and control in pharmaceutical manufacturing, thus permitting the implementation of smart manufacturing with feedback control. Fiber super-continuum lasers may emit light in the near-infrared or SWIR between approximately 1.4-1.8 microns, 2-2.5 microns, 1.4-2.4 microns, 1-1.8 microns. In particular embodiments, the detection system may be a dispersive spectrometer, a Fourier transform infrared spectrometer, or a hyper-spectral imaging detector or camera.

Abstract translation: 使用近红外或短波红外（SWIR）光源识别假冒药物的系统和方法可以使用超连续激光器进行光谱，以在非接触和非破坏性方式提供检测 或距离最小的样品制备。 此外，近红外或SWIR光可以穿透塑料容器和包装，允许在线检查和快速扫描。 近红外或SWIR光谱也可用于检测非法药物及其化学成分。 此外，光谱技术还可以应用于药物制造中的质量评估和控制，从而允许通过反馈控制实现智能制造。 光纤超连续激光器可以在大约1.4-1.8微米，2-2.5微米，1.4-2.4微米，1-1.8微米之间的近红外或者SWIR发光。 在具体实施例中，检测系统可以是色散光谱仪，傅里叶变换红外光谱仪或超光谱成像检测器或照相机。

公开(公告)号：USRE45249E1

公开(公告)日：2014-11-18

申请号：US13778006

申请日：2013-02-26

Applicant: Cymer, LLC

Inventor： Efrain Figueroa ,  William N. Partlo ,  John Martin Algots

IPC: H01S3/10

CPC classification number: H01S3/08009 ,  G01J3/02 ,  G01J3/0237 ,  G01J3/027 ,  G01J3/06 ,  G01J3/14 ,  G01J3/18 ,  G01J2003/1208 ,  G02B5/1828 ,  H01S3/08004 ,  H01S3/1055 ,  H01S3/1067

Abstract: The bandwidth selection mechanism includes a first actuator mounted on a second face of a dispersive optical element, the second face being opposite from a reflective face, the first actuator having a first end coupled to a first end block and a second end coupled to a second end block, the first actuator being operative to apply equal and opposite forces to the first end block and the second end block to bend the body of the dispersive optical element along the longitudinal axis of the body and in a first direction normal to the reflective face of the dispersive optical element. The bandwidth selection mechanism also includes a second actuator being operative to apply equal and opposite forces to bend the body along the longitudinal axis of the body, in a second direction perpendicular to the reflective face of the dispersive optical element.

Abstract translation: 所述带宽选择机构包括安装在分散光学元件的第二面上的第一致动器，所述第二面与反射面相对，所述第一致动器具有联接到第一端块的第一端和耦合到第二端的第二端 第一致动器可操作以对第一端块和第二端块施加相等且相反的力，以沿着主体的纵向轴线并沿垂直于反射面的第一方向弯曲分散光学元件的主体 的色散光学元件。 带宽选择机构还包括第二致动器，其可操作以在垂直于分散光学元件的反射面的第二方向上施加相等且相反的力沿着身体的纵向轴线弯曲身体。

公开(公告)号：US08144739B2

公开(公告)日：2012-03-27

申请号：US12605306

申请日：2009-10-23

Applicant: Efrain Figueroa ,  William N. Partlo ,  John Martin Algots

Inventor： Efrain Figueroa ,  William N. Partlo ,  John Martin Algots

IPC: H01S3/10

CPC classification number: H01S3/08009 ,  G01J3/02 ,  G01J3/0237 ,  G01J3/027 ,  G01J3/06 ,  G01J3/14 ,  G01J3/18 ,  G01J2003/1208 ,  G02B5/1828 ,  H01S3/08004 ,  H01S3/1055 ,  H01S3/1067

Abstract: The bandwidth selection mechanism includes a first actuator mounted on a second face of a dispersive optical element, the second face being opposite from a reflective face, the first actuator having a first end coupled to a first end block and a second end coupled to a second end block, the first actuator being operative to apply equal and opposite forces to the first end block and the second end block to bend the body of the dispersive optical element along the longitudinal axis of the body and in a first direction normal to the reflective face of the dispersive optical element. The bandwidth selection mechanism also includes a second actuator being operative to apply equal and opposite forces to bend the body along the longitudinal axis of the body, in a second direction perpendicular to the reflective face of the dispersive optical element.

Abstract translation: 所述带宽选择机构包括安装在分散光学元件的第二面上的第一致动器，所述第二面与反射面相对，所述第一致动器具有联接到第一端块的第一端和耦合到第二端的第二端 第一致动器可操作以对第一端块和第二端块施加相等且相反的力，以沿着主体的纵向轴线并沿垂直于反射面的第一方向弯曲分散光学元件的主体 的色散光学元件。 带宽选择机构还包括第二致动器，其可操作以在垂直于分散光学元件的反射面的第二方向上施加相等且相反的力沿着身体的纵向轴线弯曲身体。

公开(公告)号：US20070035819A1

公开(公告)日：2007-02-15

申请号：US11480287

申请日：2006-06-30

Applicant: Dar Bahatt ,  Chirag Patel ,  Roy Tan ,  Derek Prothro

Inventor： Dar Bahatt ,  Chirag Patel ,  Roy Tan ,  Derek Prothro

IPC: G02B23/00

CPC classification number: G01N21/31 ,  G01J3/10 ,  G01J3/12 ,  G01J3/18 ,  G01J3/189 ,  G01J3/2803 ,  G01J3/2823 ,  G01J3/4406 ,  G01J2003/1204 ,  G01J2003/1208 ,  G01J2003/1213 ,  G01J2003/1226 ,  G01N21/0332 ,  G01N21/253 ,  G01N21/6428 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/76 ,  G01N2021/6421 ,  G01N2021/6432 ,  G01N2201/06113 ,  G01N2201/0621 ,  G01N2201/0697

Abstract: Systems, including methods, apparatus, and algorithms, for spectrally imaging a two-dimensional array of samples.

公开(公告)号：US5087123A

公开(公告)日：1992-02-11

申请号：US526779

申请日：1990-05-17

Applicant: Edgar Gerlacher ,  Carl G. Dencks ,  Uwe Gunther ,  Gunther Rodel

Inventor： Edgar Gerlacher ,  Carl G. Dencks ,  Uwe Gunther ,  Gunther Rodel

IPC: G01J3/12 ,  G01J3/18 ,  G01J3/28 ,  G01J3/36 ,  G01J3/443 ,  G01N21/73 ,  G01N21/74

CPC classification number: G01J3/1809 ,  G01J3/443 ,  G01J2003/1208 ,  G01J2003/2869 ,  G01J3/36 ,  G01N21/73 ,  G01N21/74

Abstract: A method of and a device for multi-element measurement of elements in a sample with correction for background emission. The method starts with atomizing a sample and then exciting the transformed atoms to emit light containing characteristic spectral lines for each element, followed by generating a spectrum of spectral lines characteristic of the elements, followed by measuring the intensity of selected spectral lines falling within a predetermined measuring range without changing their intensity. The next steps are sensing the background emission adjacent the selected spectral lines simultaneously with measuring the intensity of selected spectral lines and determining the concentration of each element from the measured intensity of the corresponding spectral line and sensed background emission.

Abstract translation: 用于多元素测量样本中的元素的方法和装置，其具有用于背景发射的校正。 该方法开始于对样品进行雾化，然后激发转化的原子以发射含有每个元素的特征谱线的光，随后产生元素特征谱带的频谱，随后测量落在预定的范围内的所选谱线的强度 测量范围而不改变它们的强度。 接下来的步骤是通过测量所选谱线的强度同时测量与所选谱线相邻的背景发射，并从相应光谱线的测量强度和感测到的背景辐射确定每个元素的浓度。

公开(公告)号：US4737030A

公开(公告)日：1988-04-12

申请号：US698640

申请日：1985-02-06

Applicant: Paul H. Lee ,  Frederick B. Brown

Inventor： Paul H. Lee ,  Frederick B. Brown

IPC: G01J1/06 ,  G01J3/00 ,  G01J3/06 ,  G01J3/12 ,  G01J3/18 ,  G01J3/28 ,  G01J3/32 ,  G01J3/14

CPC classification number: G01J3/32 ,  G01J2001/067 ,  G01J2003/064 ,  G01J2003/1208 ,  G01J2003/1828 ,  G01J2003/283 ,  G01J3/0264 ,  G01J3/027

Abstract: A computer controlled optical system for automatically acquiring and storing spectral radiance data for a multiplicity of targets. Several measurement modes are available for each target ranging from a single wavelength measurement to measurement over a plurality of discrete wavelengths. Stepping motive means prompted by computer instructions direct the apparatus to a given set of target coordinates.

Abstract translation: 一种用于自动获取和存储多个目标的光谱辐射数据的计算机控制的光学系统。 从单个波长测量到多个离散波长上的测量，每个目标都有几种测量模式。 步进动机意味着由计算机指令提示将装置引导到给定的一组目标坐标。