公开(公告)号：CZ9801846A3

公开(公告)日：1998-09-16

申请号：CZ184698

申请日：1996-12-11

Applicant: BASF AG

Inventor： AMBERG WILHELM DR ,  BARLOZZARI TERESA ,  BERNARD HARALD DR ,  BUSCHMANN ERNST DR ,  HAUPT ANDREAS DR ,  HEGE HANS-GUENTHER DR ,  JANSSEN BERND DR ,  KLING ANDREAS DR ,  LIETZ HELMUT ,  RITTER KURT DR ,  ULRICH MARTINA DR ,  WEYMANN JURGEN DR ,  ZIERKE THOMAS DR

IPC: A61K38/00 ,  A61K31/00 ,  A61K38/08 ,  A61P35/00 ,  A61P35/02 ,  C07K1/00 ,  C07K7/06

CPC classification number: A61K38/08

公开(公告)号：DE3841759A1

公开(公告)日：1990-06-13

申请号：DE3841759

申请日：1988-12-12

Applicant: BASF AG

Inventor： BOEHM HANS-JOACHIM DR ,  DAUM LOTHAR DR ,  HAUPT ANDREAS DR ,  SCHMIED BERNHARD DR ,  WALKER NIGEL DR ,  ZECHEL JOHANN-CHRISTIAN DR

IPC: A61K38/00 ,  A61P29/00 ,  A61P35/00 ,  A61P37/06 ,  C07K1/04 ,  C07K7/06 ,  C07K7/08 ,  C07K7/56 ,  C07K7/64 ,  C07K14/00 ,  C07K14/52 ,  C07K14/525

Abstract: New peptides of formula X-A-Y, in which A, X and Y have the meanings given in the description, are useful therapeutic agents. A process for producing them is also described.

公开(公告)号：CZ9703765A3

公开(公告)日：1998-06-17

申请号：CZ376597

申请日：1996-06-03

Applicant: BASF AG

Inventor： HAUPT ANDREAS DR ,  EMLING FRANZ DR ,  ROMERDAHL CYNTHIA A DR

IPC: A61K38/00 ,  A61K38/08 ,  A61P35/00 ,  C07K1/04 ,  C07K5/103 ,  C07K7/06

CPC classification number: C07K7/06 ,  A61K38/00 ,  C07K5/101

公开(公告)号：CZ9703763A3

公开(公告)日：1998-06-17

申请号：CZ376397

申请日：1996-06-03

Applicant: BASF AG

Inventor： HAUPT ANDREAS DR ,  EMLING FRANZ DR ,  ROMERDAHL CYNTHIA A DR

IPC: A61K38/00 ,  A61K38/08 ,  A61P35/00 ,  C07K1/04 ,  C07K5/103 ,  C07K7/06

CPC classification number: C07K7/06 ,  A61K38/00 ,  C07K5/101

公开(公告)号：DE4415998A1

公开(公告)日：1995-11-09

申请号：DE4415998

申请日：1994-05-06

Applicant: BASF AG

Inventor： AMBERG WILHELM DR ,  BERNARD HARALD DR ,  BUSCHMANN ERNST DR ,  HAUPT ANDREAS DR ,  JANITSCHKE LOTHAR DR ,  JANSSEN BERND DR ,  KARL ULRICH DR ,  KLING ANDREAS DR ,  MUELLER STEFAN DR ,  POTZOLLI BERND DE DR ,  RITTER KURT DR ,  ZIERKE THOMAS DR ,  THYES MARCO DR

IPC: A61K38/00 ,  A61P35/00 ,  C07K5/10 ,  C07K5/103 ,  C07K7/06

Abstract: Compounds of formula (I) are disclosed, wherein R , R , R , and R have the meanings indicated in the description, as well as a process for the production of these compounds. The compounds are suitable for use as starting material for the synthesis of substances which have anti-tumour properties.

公开(公告)号：DE4415997A1

公开(公告)日：1995-11-09

申请号：DE4415997

申请日：1994-05-06

Applicant: BASF AG

Inventor： AMBERG WILHELM DR ,  BERNARD HARALD DR ,  BUSCHMANN ERNST DR ,  HAUPT ANDREAS DR ,  JANITSCHKE LOTHAR DR ,  JANSSEN BERND DR ,  KARL ULRICH DR ,  KLING ANDREAS DR ,  MUELLER STEFAN DR ,  POTZOLLI BERND DE DR ,  RITTER KURT DR ,  ZIERKE THOMAS DR ,  THYES MARCO DR

IPC: A61K38/00 ,  A61K38/08 ,  A61P35/00 ,  C07K1/08 ,  C07K5/10 ,  C07K5/103 ,  C07K7/06 ,  C07K14/52

Abstract: Disclosed is the compound Me2Val-Val-MeVal-Pro-Pro-NHBzl. HCl. The compound is produced from Z-Val-Val-MeVal-Pro-OR , wherein Z and R have the meanings indicated in the description. The compound disclosed has anti-neoplastic properties.

公开(公告)号：DE3841768A1

公开(公告)日：1990-06-13

申请号：DE3841768

申请日：1988-12-12

Applicant: BASF AG

Inventor： BOEHM HANS-JOACHIM DR ,  DAUM LOTHAR DR ,  HAUPT ANDREAS DR ,  SCHMIED BERNHARD DR ,  WALKER NIGEL DR ,  ZECHEL JOHANN-CHRISTIAN DR

IPC: A61K38/00 ,  A61P29/00 ,  A61P35/00 ,  A61P37/06 ,  C07K1/04 ,  C07K7/06 ,  C07K7/08 ,  C07K7/56 ,  C07K7/64 ,  C07K14/52 ,  C07K14/525

Abstract: New peptides of formula X-A-Gly-B-Y, in which A, B, X and Y have the meanings given in the description, are useful therapeutic agents. A process for producing them is also described.

公开(公告)号：DE3841753A1

公开(公告)日：1990-06-13

申请号：DE3841753

申请日：1988-12-12

Applicant: BASF AG

Inventor： BOEHM HANS-JOACHIM DR ,  DAUM LOTHAR DR ,  HAUPT ANDREAS DR ,  SCHMIED BERNHARD DR ,  WALKER NIGEL DR ,  ZECHEL JOHANN-CHRISTIAN DR

IPC: A61K38/00 ,  A61P29/00 ,  A61P35/00 ,  A61P37/06 ,  C07K1/04 ,  C07K7/06 ,  C07K7/08 ,  C07K7/64 ,  C07K14/52 ,  C07K14/525

Abstract: Peptides derived from TNF, of formula (I): X-A-Gly-Asp-Y, in which A X and Y have the meanings given in the description. Process for producing them. The novel peptides are useful therapeutic agents.

公开(公告)号：CZ376397A3

公开(公告)日：1998-06-17

申请号：CZ376397

申请日：1996-06-03

Applicant: BASF AG

Inventor： HAUPT ANDREAS DR ,  EMLING FRANZ DR ,  ROMERDAHL CYNTHIA A DR

IPC: A61K38/00 ,  A61K38/08 ,  A61P35/00 ,  C07K1/04 ,  C07K5/103 ,  C07K7/06

Abstract: Novel compounds of the formulaR1R2N-CHX-CO-A-B-D-(E)s-(F)t-(G)U-KIin which R1, R2, A, B, D, E, F, G, K, X, s, t, and u have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.

公开(公告)号：DE4120327A1

公开(公告)日：1992-12-24

申请号：DE4120327

申请日：1991-06-20

Applicant: BASF AG

Inventor： SCHMIDT ULRICH PROF DR ,  GRIESSER HELMUT ,  HAAS GERHARD DR ,  KRONER MATTHIAS DR ,  RIEDL BERND ,  EMLING FRANZ DR ,  HAUPT ANDREAS DR ,  KLUGE MICHAEL DR

IPC: A61K38/00 ,  A61K38/12 ,  A61P31/12 ,  A61P35/00 ,  A61P37/00 ,  C07K5/08 ,  C07K11/02

Abstract: Described are peptides of formula (I), in which R , R , R , R , R , X and X are as defined in the description, as well as their preparation. The new peptides are suitable for use in the treatment of illnesses.