3.
    发明专利
    未知

    公开(公告)号:DE50211588D1

    公开(公告)日:2008-03-13

    申请号:DE50211588

    申请日:2002-07-26

    Applicant: BASF AG

    Abstract: Continuous production of 5-alkoxy oxazoles (I) comprises heating an alkyl alpha -isocyanoalkanoate ester (II) at a temperature above 80 degrees C in the presence of an auxiliary agent and withdrawing the product from the reactor. Continuous production of 5-alkoxy oxazoles of formula (I) comprises heating an alkyl alpha -isocyanoalkanoate ester of formula (II) at a temperature above 80 degrees C in the presence of an auxiliary agent and withdrawing the product from the reactor. R1 = optionally substituted 1-6C alkyl; R2 = H or optionally substituted 1-6C alkyl. An Independent claim is also included for a process for producing pyridoxine derivatives of formula (IX), comprising: (1) converting an amino acid of formula (III) to an ester of formula (IV); (2) converting (IV) to a formamido ester of formula (IV); (3) converting (IV) to (II); (4) converting (II) to (I) as above; (5) reacting (I) with a protected diol of formula (VI) to form a Diels-Alder adduct of formula (VII); and (6) converting (VII) to (IX) by acid treatment and deprotection. R3, R4 = protecting groups or together form a protecting group.

    5.
    发明专利
    未知

    公开(公告)号:DE50012953D1

    公开(公告)日:2006-07-27

    申请号:DE50012953

    申请日:2000-05-24

    Applicant: BASF AG

    Abstract: Alkyne diol preparation from a carbonyl compound and acetylene uses an alkali metal salt prepared in situ as an alcoholate a catalyst. Preparation of alkyne diol of formula (I)comprises reacting a carbonyl compound of formula (II) with acetylene in the prese of an alkali metal salt as catalyst and a polar aprotic solvent. R R C(OH)-C IDENTICAL C-C(OH)R R (I) R -C(=O)-R (II) R and R = H or 1-20C hydrocarbon optionally substituted by 1-6C alkyl and/or halogen and/or interrupted by halogen and/or containing a CC double or triple bond.

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