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公开(公告)号:FI952961A0
公开(公告)日:1995-06-15
申请号:FI952961
申请日:1995-06-15
Applicant: BASF AG
Inventor: HAUPT ANDREAS , JANSSEN BERND , RITTER KURT , KLINGE DAGMAR , KEILHAUER GERHARD , ROMERDAHL CYNTHIA , BARLOZZARI TERESA , QIAN XIAO-DONG
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公开(公告)号:CA2136339A1
公开(公告)日:1993-11-25
申请号:CA2136339
申请日:1993-05-10
Applicant: BASF AG
Inventor: HAUPT ANDREAS , EMLING FRANZ , ROMERDAHL CYNTHIA
IPC: A61K38/00 , A61K38/08 , A61P35/00 , A61P35/02 , C07K5/062 , C07K5/08 , C07K5/083 , C07K5/087 , C07K5/10 , C07K5/103 , C07K5/107 , C07K7/06 , C07K5/02 , C07K7/02 , A61K38/04 , C07K5/04
Abstract: 2136339 9323424 PCTABS00028 Novel derivates of dolastatin of formula (I) in which R1, R2, A, B, D, E, F, G, K, X, t, u, v, and w have the meanings stated in the description, and the preparation thereof are described. The novel substances have an antineoplastic effect.
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公开(公告)号:CA2005281A1
公开(公告)日:1990-06-12
申请号:CA2005281
申请日:1989-12-12
Applicant: BASF AG
Inventor: BOEHM HANS-JOACHIM , DAUM LOTHAR , HAUPT ANDREAS , SCHMIED BERNHARD , WALKER NIGEL , ZECHEL JOHANN-CHRISTIAN
IPC: A61K38/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07K1/04 , C07K7/06 , C07K7/08 , C07K7/56 , C07K7/64 , C07K14/52 , C07K14/525 , A61K38/02 , A61K38/08
Abstract: - 33 - O. Z . 0050/40383 Peptides of the formula X-A-Asn-B-Y, where A, B, X and Y are defined in the description, and the preparation thereof are described. The novel peptides are suitable for controlling diseases.
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公开(公告)号:CA2005051A1
公开(公告)日:1990-06-12
申请号:CA2005051
申请日:1989-12-11
Applicant: BASF AG
Inventor: BOEHM HANS-JOACHIM , DAUM LOTHAR , HAUPT ANDREAS , SCHMIED BERNHARD , WALKER NIGEL , ZECHEL JOHANN-CHRISTIAN
IPC: A61K38/00 , A61P29/00 , A61P35/00 , A61P37/06 , C07K1/04 , C07K7/06 , C07K7/08 , C07K7/56 , C07K7/64 , C07K14/52 , C07K14/525 , A61K38/08 , A61K38/10 , A61K38/12 , A61K38/19 , C07K7/50
Abstract: Peptides of the formula X-A-Gly-B-Y, where A, B, X and Y are defined in the description, and the preparation thereof are described. The novel peptides are suitable for controlling diseases.
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公开(公告)号:CA2189691C
公开(公告)日:2011-02-15
申请号:CA2189691
申请日:1995-04-26
Applicant: BASF AG
Inventor: AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANITSCHKE LOTHAR , JANSSEN BERND , KARL ULRICH , KLING ANDREAS , MULLER STEFAN , DE POTZOLLI BERND , RITTER KURT , THYES MARCO , ZIERKE THOMAS
Abstract: Compounds of formula (I) are disclosed, wherein R1, R2, R3, and R4 have the meanings indicated in the description, as well as a process for the production of these compounds. The compounds are suitable for use as starting material for the synthesis of substances which have anti-tumour properties.
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公开(公告)号:PL351441A1
公开(公告)日:2003-04-22
申请号:PL35144100
申请日:2000-03-28
Applicant: BASF AG
Inventor: HILLEN HEINZ , SCHMIDT MARTIN , MACK HELMUT , SEITZ WERNER , HAUPT ANDREAS , ZECHEL JOHANN-CHRISTIAN , KLING ANDREAS
IPC: A61K38/00 , A61K38/55 , A61P1/04 , A61P1/18 , A61P5/14 , A61P7/02 , A61P9/00 , A61P9/10 , C12N9/99 , A61P11/00 , A61P11/06 , A61P13/12 , A61P15/00 , A61P17/02 , A61P19/02 , A61P21/04 , A61P25/00 , A61P25/28 , A61P29/00 , A61P37/02 , C07B43/00 , C07D401/12 , C07D409/12 , C07K5/06 , C07K5/062 , C07K5/065 , C07K5/068 , C07K5/072 , C07K5/078 , A61K38/05
Abstract: Peptide substances, their preparation and their use as complement inhibitors are described. These are in particular substances having a guanidine or amidine radical as a terminal group. In particular, inhibitors of the complement proteases C1s and C1r are described.
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公开(公告)号:MXPA01010114A
公开(公告)日:2002-07-30
申请号:MXPA01010114
申请日:2000-03-28
Applicant: BASF AG
Inventor: HAUPT ANDREAS
IPC: A61K38/00 , A61K38/55 , A61P1/04 , A61P1/18 , A61P5/14 , A61P7/02 , A61P9/00 , A61P9/10 , A61P11/00 , C12N9/99 , A61P11/06 , A61P13/12 , A61P15/00 , A61P17/02 , A61P19/02 , A61P21/04 , A61P25/00 , A61P25/28 , A61P29/00 , A61P37/02 , C07B43/00 , C07D401/12 , C07D409/12 , C07K5/06 , C07K5/062 , C07K5/065 , C07K5/068 , C07K5/072 , C07K5/078
Abstract: La invencion se refiere a las sustancias peptidicas, a la produccion de tales sustancias y a su uso como inhibidores de complemento. En particular, la invencion se refiere a las sustancias con un radical guanidina o amidina como grupo terminal, en especial a los inhibidores de las proteasas complemento Cls y Clr.
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公开(公告)号:DE69803792D1
公开(公告)日:2002-03-21
申请号:DE69803792
申请日:1998-09-24
Applicant: BASF AG
Inventor: BARLOZZARI TERESA , BANERJEE SUBHASHIS , HAUPT ANDREAS
Abstract: The present invention provides compositions and methods for the treatment of rheumatoid arthritis in a subject wherein one or more compounds of Formula I as defined herein alone or in combination with one or more other antiarthritic drugs provide suppression of rheumatoid arthritis.
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公开(公告)号:SI9520061B
公开(公告)日:2002-02-28
申请号:SI9520061
申请日:1995-04-26
Applicant: BASF AG
Inventor: AMBERG WILHELM , BERNARD HARALD , BUSCHMANN ERNST , HAUPT ANDREAS , JANITSCHKE LOTHAR , JANSSEN BERND , KARL ULRICH , KLING ANDREAS , MUELLER STEFAN , DE POTZOLLI BERND , RITTER KURT , THYES MARCO , ZIERKE THOMAS
Abstract: PCT No. PCT/EP95/01577 Sec. 371 Date Nov. 4, 1996 Sec. 102(e) Date Nov. 4, 1996 PCT Filed Apr. 26, 1995 PCT Pub. No. WO95/30691 PCT Pub. Date Nov. 16, 1995The compound Me2Val-Val-MeVal-Pro-Pro-NHBzlxHCl is described. It is prepared from Z-Val-Val-MeVal-Pro-OR1 where Z and R1 have the meanings stated in the description. The compound shows antineoplastic activity.
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