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公开(公告)号:DE19624701A1
公开(公告)日:1998-01-02
申请号:DE19624701
申请日:1996-06-20
Applicant: BASF AG
Inventor: EHLE BEATE DR , BAUR RICHARD DR , OETTER GUENTER DR , KAHMEN MARTIN AUS DEM DR , KARL ULRICH DR
IPC: C11D1/10 , C11D1/29 , C11D1/52 , C11D1/66 , C11D1/72 , C11D1/83 , C11D3/08 , C11D3/10 , C11D3/12 , C11D3/33 , C11D17/00 , C11D17/06 , C11D3/02 , C11D3/386 , C11D3/395
Abstract: Phosphate free washing agent comprising (a) 1-60 wt. % of at least one inorganic builder, (b) 0.1-25 wt. % of at least one anionic detergent of formula R -CH(OH)-CH(R )-N(R )-Y-COOM (I) , (c) optionally 0-40 wt. % of at least one further anionic detergent, (d) 0.5-30 wt. % of at least one nonionic detergent, and optionally washing and cleaning agents. R , R = H, aryl, alkyl or alkenyl (both optionally substituted with 1-3 residues selected from aryloxy or alkoxycarbonyl and/or interrupted by 1-5 non-adjacent O atoms), or R and R together with the groups to which they are bound may form the residue of a mono- or polyunsaturated fatty acid which forms, by way of an ester bond, part of a triglyceride, which (depending on the original number of double bonds in its fatty acid residue, having up to 9 groups of formula (I) (sic), R = H, alkyl, -CHR -CH(OH)-R (IIa) or -(CH2)n-COOM (IIb); n = 1-4; R , R = as for R and R , and the sum of the C atoms in R , R , R and R \- 4; Y = alkylene (optionally substituted by OH and/or COOM), or R +N+Y = a 5- or 6-membered, saturated or unsaturated heterocyclic ring; M = H, alkali(ne earth) metal, optionally substituted ammonium.
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公开(公告)号:DE4415998A1
公开(公告)日:1995-11-09
申请号:DE4415998
申请日:1994-05-06
Applicant: BASF AG
Inventor: AMBERG WILHELM DR , BERNARD HARALD DR , BUSCHMANN ERNST DR , HAUPT ANDREAS DR , JANITSCHKE LOTHAR DR , JANSSEN BERND DR , KARL ULRICH DR , KLING ANDREAS DR , MUELLER STEFAN DR , POTZOLLI BERND DE DR , RITTER KURT DR , ZIERKE THOMAS DR , THYES MARCO DR
Abstract: Compounds of formula (I) are disclosed, wherein R , R , R , and R have the meanings indicated in the description, as well as a process for the production of these compounds. The compounds are suitable for use as starting material for the synthesis of substances which have anti-tumour properties.
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公开(公告)号:DE4415997A1
公开(公告)日:1995-11-09
申请号:DE4415997
申请日:1994-05-06
Applicant: BASF AG
Inventor: AMBERG WILHELM DR , BERNARD HARALD DR , BUSCHMANN ERNST DR , HAUPT ANDREAS DR , JANITSCHKE LOTHAR DR , JANSSEN BERND DR , KARL ULRICH DR , KLING ANDREAS DR , MUELLER STEFAN DR , POTZOLLI BERND DE DR , RITTER KURT DR , ZIERKE THOMAS DR , THYES MARCO DR
Abstract: Disclosed is the compound Me2Val-Val-MeVal-Pro-Pro-NHBzl. HCl. The compound is produced from Z-Val-Val-MeVal-Pro-OR , wherein Z and R have the meanings indicated in the description. The compound disclosed has anti-neoplastic properties.
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公开(公告)号:DE4235603A1
公开(公告)日:1994-04-28
申请号:DE4235603
申请日:1992-10-22
Applicant: BASF AG
Inventor: RENDENBACH-MUELLER BEATRICE DR , KARL ULRICH DR , WEIFENBACH HARALD DR
IPC: C07D311/16 , C07D405/12 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D311/06 , C07D335/06 , C07D311/78 , A61K31/41 , A61K31/42 , A61K31/425
Abstract: Arylalkoxythiocoumarins of the formula in which R and R independently of one another represent hydrogen, C1- to C5-alkyl, trifluoromethyl, phenyl, halogen or together represent a C3-C5-alkylene chain; additionally X is oxygen or sulphur; R is C1- to C5- alkyl or halogen; n is an integer from 0 to 3; R is hydrogen or C1- to C4- alkyl and Ar is phenyl, which can be mono- to disubstituted by halogen, C1-C6-alkyl, C3-C7-cycloalkyl, C1-C6-alkoxy, nitro, cyano, trifluoromethyl or a combination of these substituents or is a heteroaromatic ring having one to three heteroatoms which independently of one another can be N, O or S, and which can be substituted by C1-C6-alkyl, C3-C7-cycloalkyl, C1-C6-alkoxy, C1-C4-alkoxy-substituted C1-C6-alkyl, 5-6-membered oxacycloalkyl, benzyl, C1-C5-alkoxycarbonyl, perfluoro-C1-C2-alkyl, phenyl or halogen, a process for their preparation and therapeutic agents containing them, in particular for the treatment of central nervous disorders.
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公开(公告)号:CZ288448B6
公开(公告)日:2001-06-13
申请号:CZ326096
申请日:1995-04-26
Applicant: BASF AG
Inventor: AMBERG WILHELM DR , BERNARD HARALD DR , BUSCHMANN ERNST DR , HAUPT ANDREAS DR , JANITSCHKE LOTHAR DR , MUELLER STEFAN DR , DE POTZOLLI BERND DR , RITTER KURT DR , THYES MARCO DR , ZIERKE THOMAS DR , JANSSEN BERND DR , KARL ULRICH DR , KLING ANDREAS DR
Abstract: In the present invention, there is described pentapeptide hydrochloride of the formula Mei2Val-Val-MeVal-Pro-Pro-NHBz1.HCl, which is present in crystalline form. It is prepared from the compound of the formula Z-Val-Val-MeVal-Pro-ORe1, in which Z represents a benzyloxycarbonyl protecting group, which might be optionally substituted on the phenyl ring and Re1 represents alkyl containing 1 to 5 carbon atoms. In the present invention, there are also described intermediates for preparing the above indicated pentapeptide hydrochloride. The above-described compound exhibits antineoplastic activity.
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公开(公告)号:DE19703447A1
公开(公告)日:1998-08-06
申请号:DE19703447
申请日:1997-01-30
Applicant: BASF AG
Inventor: POTTHOFF-KARL BIRGIT DR , GREINDL THOMAS DR , KARL ULRICH DR , FREYBERG PETER DR , HOIS PIA DR
IPC: C07C229/16 , D06M13/192 , D06M13/342 , D06P1/647 , D06P5/06 , D06P5/22
Abstract: The use of bis-(dicarboxylic acid) diaminoalkylene derivatives of formula (I) as complex-forming agents in textile dyeing and pre- or post-treatment is claimed. In (I), R , R = H, 1-8C alkyl, 2-8C alkenyl, phenyl, benzyl, or 1-4C hydroxyalkyl or hydroxy-halo-alkyl; M = H, alkali metal, ammonium or substituted ammonium; l, m, n = 0-6; A1 = 2-3C alkylene, optionally substituted on one, two or all C atoms with one or two hydroxy, 1-6C alkyl, 2-6C alkenyl, 3-6C cycloalkyl, or 3-8C cycloalkenyl, aryl, alkylaryl, heteroaryl or alkyl-heteroaryl groups. Also claimed are: (i) a process for the pretreatment, post-treatment or dyeing of textiles or textile precursors in the manufacture or processing of textiles, in which the material is subjected to a treatment bath containing 0.01-20 (preferably 0.1-10, more preferably 0.5-3) g/l (I), and (ii) baths used for this process containing (I) in the above amounts.
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17.
公开(公告)号:CZ9800243A3
公开(公告)日:1998-07-15
申请号:CZ24398
申请日:1996-07-12
Applicant: BASF AG
Inventor: AMBERG WILHELM DR , BERNARD HARALD DR , BUSCHMANN ERNST DR , HAUPT ANDREAS DR , JANSSEN BERND DR , KARL ULRICH DR , KLING ANDREAS DR , MULLER STEFAN DR , RITTER KURT DR , ZIERKE THOMAS DR
IPC: C07K1/02 , C07K1/12 , C07K5/078 , C07K5/083 , C07K5/103 , C07K7/06 , C07K5/06 , C07K5/08 , C07K5/10
CPC classification number: C07K7/06 , C07K5/06165 , C07K5/0808 , C07K5/101
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公开(公告)号:DE19624702A1
公开(公告)日:1998-01-02
申请号:DE19624702
申请日:1996-06-20
Applicant: BASF AG
Inventor: EHLE BEATE DR , POTTHOFF-KARL BIRGIT DR , KAHMEN MARTIN AUS DEM DR , KARL ULRICH DR , ZIMMERMANN NORBERT , WAGENMANN HENRIC DR
IPC: C09B67/46 , C09K23/00 , C09K23/28 , C11D3/33 , C11D3/42 , D06L3/12 , D06L4/614 , D06L4/671 , D06M13/342 , D06M13/35 , D06P1/16 , D06P1/22 , D06P1/642 , D06P1/647 , B01F17/28 , C09B67/02 , C14C3/08 , C14C3/28
Abstract: Hydroxyalkylaminocarboxylic acid derivatives of formula (I) R -CH(OH)-CH(R )-N(R )-Y-COOM (I) are used as dispersing agent in dyestuffs or in preparations containing UV absorbers or optical brighteners. In (I), R and R = H, aryl, alkyl or alkenyl and the alkyl or alkenyl groups may be substituted with 1,2 or 3 residues selected from aryloxy or alkoxycarbonyl and/or interrupted by 1, 2, 3,4 or 5 non-adjacent O atoms, or R and R together with the groups to which they are bound may form the residue of a mono- or polyunsaturated fatty acid which forms, by way of an ester bond, part of a triglyceride, this triglyceride, depending on the original number of double bonds in its fatty acid residue, having up to 9 groups of formula (I), R = H, alkyl, -CHR -CH(OH)-R (IIa) or -(CH2)n-COOM (IIb) (where n = a whole number 1-4, R and R = as for R and R , and the sum of the C atoms in R , R , R and R = at least 4), Y = alkylene which may be substituted by an OH group and/or a group of formula COOM), or R and Y may together complete a 5- or 6-membered, saturated or unsaturated heterocyclic ring and M = H, alkali(ne earth) metal, ammonium or substituted ammonium. Also claimed is use of (I) in dye baths for dyeing with dispersion dyes using the exhaustion process, in dye baths for dyeing with vat dyes and in textile treatment liquors containing UV absorbers or optical brighteners.
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公开(公告)号:CZ9603260A3
公开(公告)日:1997-04-16
申请号:CZ326096
申请日:1995-04-26
Applicant: BASF AG
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公开(公告)号:DE19527575A1
公开(公告)日:1997-01-30
申请号:DE19527575
申请日:1995-07-28
Applicant: BASF AG
Inventor: AMBERG WILHELM DR , BERNARD HARALD DR , BUSCHMANN ERNST DR , HAUPT ANDREAS DR , JANSSEN BERND DR , KARL ULRICH DR , KLING ANDREAS DR , MUELLER STEFAN DR , RITTER KURT DR , ZIERKE THOMAS DR
IPC: C07K1/02 , C07K1/12 , C07K5/06 , C07K5/078 , C07K5/08 , C07K5/083 , C07K5/10 , C07K5/103 , C07K7/06 , A61K38/08
Abstract: The description relates to a process for producing pentapeptides of the formula (I) in which A and R -R have the meanings given, in which the pentapeptide is constructed in steps from a prolinamide of the formula (II) in which R and R have the meanings given above, and the group -NR R may be hydrolytically separated from the peptide thus obtained.
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