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    2-(PYRIDIN-2-YL)-PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI
    13.
    发明专利
    2-(PYRIDIN-2-YL)-PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI 未知

    公开(公告)号：CA2573366A1

    公开(公告)日：2006-02-02

    申请号：CA2573366

    申请日：2005-07-22

    Applicant: BASF AG

    Inventor： BLETTNER CARSTEN ,  GROTE THOMAS ,  STRATHMANN SIEGFRIED ,  STIERL REINHARD ,  RETHER JAN ,  SCHERER MARIA ,  SCHAEFER PETER ,  GRAMMENOS WASSILIOS ,  RHEINHEIMER JOACHIM ,  HUENGER UDO ,  MUELLER BERND ,  GEWEHR MARKUS ,  KOEHLE HARALD ,  SCHOEFL ULRICH ,  SCHWOEGLER ANJA ,  SCHIEWECK FRANK

    IPC: C07D401/04 ,  A01N43/54

    Abstract: 2-Pyridyl pyrimidine derivatives (I) are new. 2-Pyridyl pyrimidine derivatives of formula (I) and their salts are new. k : 0-3; m : 0-5; n : 1-5; R 1>halo, OH, CN, NO 2, 1-4C (halo)alkyl, 104C (halo)alkoxy, 2-4C alkenyl, 2-4C alkynyl, 3-8C cycloalkyl, (1-4C)alkoxy(1-4C)alkyl, NH 2, phenoxy (optionally substituted with halo or 1-4C alkyl), NHR, NRR, C(Ra)=NORb, SO pA 1> or COA 2>; or R 1>+R 1>1-4C (halo)alkylenedioxy; R : 1-4C alkyl or 1-4C alkylcarbonyl; Ra : H or 1-4C alkyl; Rb : 1-4C alkyl, 3-4C alkenyl or 3-4C alkynyl; p : 0-2; A 1>1-4C alkyl, or also NH 2, 1-4C alkylamino or di(1-4C alkyl)amino when p = 2; A 2>H, OH, 1-4C alkyl, 1-4C alkylamino, di(1-4C alkyl)amino, 2-4C alkenyl or 1-4C (halo)alkoxy; R 2>1-4C haloalkyl, 1-4C (halo)alkoxy, OH, halo, CN or NO 2, or R 2> can be H or 1-4C alkyl if n = 3-5 and/or k = 1-3 and/or at least one R 1> is other than halo, 1-4C (halo)alkyl and 1-4C alkoxy; and R 3>1-4C alkyl. An independent claim is also included for controlling phytopathogenic fungi by treating the fungi, or materials, plants, soil or seeds to be protected from fungal attack, with a compound (I). [Image] ACTIVITY : Plant antifungal. In a protective test against Alternaria solani on tomato plants, plants treated with 2-(5-methyl-6-phenyl-2-pyridyl)-4,5-pentamethylene-pyrimidine (250 ppm) suffered no attack, whereas 90% of untreated plants were attacked. MECHANISM OF ACTION : None given.

    ANILIDAS DEL ACIDO TRIFLUOROMETIL-TIOFENCARBOXILICO Y SU USO COMO FUNGICIDAS
    16.
    发明专利
    ANILIDAS DEL ACIDO TRIFLUOROMETIL-TIOFENCARBOXILICO Y SU USO COMO FUNGICIDAS 未知

    公开(公告)号：CO5631439A2

    公开(公告)日：2006-04-28

    申请号：CO05108202

    申请日：2005-10-24

    Applicant: BASF AG

    Inventor： GEWEHR MARKUS ,  MULLER BERND ,  GROTE THOMAS ,  GRAMMENOS WASSILIOS ,  GYPSER ANDREAS ,  TORMO I BLASCO JORDI ,  SCHWOGLER ANJA ,  RHEINHEIMER JOACHIM ,  BLETTNER CARSTEN ,  SCHIEWECK FRANK ,  RACK MICHAEL ,  SCHOFL ULRICH ,  STRTHMANN SIEGFRED ,  STIERL REINHARD ,  RETHER JAN

    IPC: C07D333/12 ,  C07D333/38

    Abstract: 1.- Anilidas del ácido trifluorometil-tiofencarboxílico caracterizadas porque tienen las fórmulas generales I, II y III, en las cuales los sustituyentes tienen el siguiente significado:R1, R4, independientemente el uno del otro, alquilo C1-C4, cicloalquilo C3-C6, alquenilo C2-C4, alquinilo C2-C4, alcoxi-C1-C4 -pudiendo esos grupos estar sustituidos por halógeno-, H, halógeno, nitro, CN;R2 alquilo C1-C4, cicloalquilo C3-C6, alcoxi-C1-C4, pudiendo esos grupos estar sustituidos por halógeno, H, OH;R3 alquilo-C2-C12, cicloalquilo-C3-C12, alquenilo-C2-C12, cicloalquenilo C5-C12, alquinilo-C2-C12, cicloalquilo-C3-C12-alquilo-C1-C4, pudiendo esos grupos estar sustituidos por R7; fenilo, fenilalquilo-C1-C6, fenilalquenilo-C2-C6, fenilalquinilo-C1-C6, feniloxi-alquenilo-C2-C6-, feniloxi-alquinilo C2-C6, pudiendo el resto alquilo, alquenilo y alquinilo estar substituidos por R7 y el anillo fenilo por R5;-C(RS) NOR6;X O, S o enlace directo;R5 H, alquilo-C1-C4, cicloalquilo-C3-C6, alcoxi-C1-C4, alquenilo-C2-C4, alquinilo-C2-C4 - pudiendo esos grupos estar sustituidos por halógeno -, halógeno, nitro, CN, fenilo, que puede estar sustituido por R1, fenoxi, que puede estar sustituido por R1, alquil-C1-C6-fenilo, pudiendo el resto alquilo estar sustituido por halógeno, y el anillo fenilo estar sustituido por R1;R6 alquilo-C1-C4, cicloalquilo-C3-C6, alquenilo-C2-C4, alquinilo-C2-C4, pudiendo esos grupos estar sustituidos por halógeno, fenilo, que puede estar sustituido por R1;R7 alquilo-C1-C4, alcoxi-C1-C8, alqueniloxi-C2-C8, alquiniloxi-C2-C8, alcoxi-C1-C4-alcoxi-C1-C8 - pudiendo esos grupos estar sustituidos por halógeno -, halógeno;R8 H, R7 o alquilo-C1-C12, cicloalquilo-C3-C12, alquenilo-C2-C12, cicloalquenilo-C5-C12, cicloalquil-C3-C12-alquilo-C1-C4, pudiendo esos grupos estar sustituidos por halógeno; fenilo, que puede estar sustituido por R5;n 0-4 m 0,1.

    2-(pyridin-2-yl)-pyrimidines and their use for controlling pathogenic fungi
    18.
    发明专利
    2-(pyridin-2-yl)-pyrimidines and their use for controlling pathogenic fungi 未知

    公开(公告)号：AU2005266555A1

    公开(公告)日：2006-02-02

    申请号：AU2005266555

    申请日：2005-07-22

    Applicant: BASF AG

    Inventor： GROTE THOMAS ,  MULLER BERND ,  STIERL REINHARD ,  RHEINHEIMER JOACHIM ,  SCHWOGLER ANJA ,  GRAMMENOS WASSILIOS ,  SCHERER MARIA ,  SCHOFL ULRICH ,  GEWEHR MARKUS ,  SCHAFER PETER ,  STRATHMANN SIEGFRIED ,  RETHER JAN ,  BLETTNER CARSTEN ,  HUNGER UDO ,  SCHIEWECK FRANK ,  KOHLE HARALD

    IPC: C07D401/04 ,  A01N43/54

    Abstract: 2-Pyridyl pyrimidine derivatives (I) are new. 2-Pyridyl pyrimidine derivatives of formula (I) and their salts are new. k : 0-3; m : 0-5; n : 1-5; R 1>halo, OH, CN, NO 2, 1-4C (halo)alkyl, 104C (halo)alkoxy, 2-4C alkenyl, 2-4C alkynyl, 3-8C cycloalkyl, (1-4C)alkoxy(1-4C)alkyl, NH 2, phenoxy (optionally substituted with halo or 1-4C alkyl), NHR, NRR, C(Ra)=NORb, SO pA 1> or COA 2>; or R 1>+R 1>1-4C (halo)alkylenedioxy; R : 1-4C alkyl or 1-4C alkylcarbonyl; Ra : H or 1-4C alkyl; Rb : 1-4C alkyl, 3-4C alkenyl or 3-4C alkynyl; p : 0-2; A 1>1-4C alkyl, or also NH 2, 1-4C alkylamino or di(1-4C alkyl)amino when p = 2; A 2>H, OH, 1-4C alkyl, 1-4C alkylamino, di(1-4C alkyl)amino, 2-4C alkenyl or 1-4C (halo)alkoxy; R 2>1-4C haloalkyl, 1-4C (halo)alkoxy, OH, halo, CN or NO 2, or R 2> can be H or 1-4C alkyl if n = 3-5 and/or k = 1-3 and/or at least one R 1> is other than halo, 1-4C (halo)alkyl and 1-4C alkoxy; and R 3>1-4C alkyl. An independent claim is also included for controlling phytopathogenic fungi by treating the fungi, or materials, plants, soil or seeds to be protected from fungal attack, with a compound (I). [Image] ACTIVITY : Plant antifungal. In a protective test against Alternaria solani on tomato plants, plants treated with 2-(5-methyl-6-phenyl-2-pyridyl)-4,5-pentamethylene-pyrimidine (250 ppm) suffered no attack, whereas 90% of untreated plants were attacked. MECHANISM OF ACTION : None given.

    MEVALONATE KINASE AS A TARGET FOR FUNGICIDES
    19.
    发明专利
    MEVALONATE KINASE AS A TARGET FOR FUNGICIDES 未知

    公开(公告)号：CA2514694A1

    公开(公告)日：2004-08-19

    申请号：CA2514694

    申请日：2004-01-28

    Applicant: BASF AG

    Inventor： RETHER JAN ,  FREUND ANNETTE ,  LACOUR THIERRY ,  SCHMIDT RALF-MICHAEL

    IPC: C12N9/12 ,  C12N15/54 ,  C12Q1/02 ,  G01N33/50

    Abstract: The present invention relates to the provision of mevalonate kinase as target for fungicides, to the provision of novel nucleic acid sequences, of functional equivalents of the abovementioned nucleic acid sequences and to the use of the gene products of the abovementioned nucleic acid sequences as novel targets for fungicides. Moreover, the present invention relates to methods for identifying fungicides which inhibit a polypeptide with the biological activity of a mevalonate kinase and to the use of these compounds identified via the abovementioned method as fungicides.

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