公开(公告)号：EP1946119B1

公开(公告)日：2010-10-27

申请号：EP05808964.0

申请日：2005-09-14

Applicant: Korea Basic Science Institute

Inventor： AHN, Yeong Hee ,  KWON, Kyung-Hoon ,  YOO, Jong Shin

IPC: G01N33/68

CPC classification number: C07K14/4732

Abstract: The present invention relates to a method for analyzing modified polypeptide sequence and modified information thereof. More precisely, the invention relates to a method for identifying modified peptide in which fragment ion signals are obtained from target peptide precursor by using tandem mass spectrometry, candidate peptides and every possible peptide fragmentation patterns thereof are designed based on the mass data thereby, match scores corresponding to each fragmentation pattern of candidate peptides are given, and then by combining each matching scores derived from possible fragmentation patterns of a candidate peptide, modified target polypeptide is identified by tandem mass data based on the provided match score. The scoring method for modified polypeptide of the present invention can greatly contribute to increasing searching efficiency of modified peptides and reliability of the searching results by integrating all scored values obtained from different fragmentation patterns of a candidate peptide.

公开(公告)号：EP1799845B1

公开(公告)日：2010-09-15

申请号：EP04793448.4

申请日：2004-10-08

Applicant: Korea Basic Science Institute

Inventor： AHN, Yeong Hee ,  YOO, Jong Shin ,  LEE, Jae Yong ,  KIM, Jin Young ,  0HO, Kun

IPC: G01N33/68 ,  C12Q1/37

CPC classification number: G01N33/6842 ,  G01N33/6848

公开(公告)号：EP1654267B1

公开(公告)日：2010-04-21

申请号：EP03818122.8

申请日：2003-08-14

Applicant: Korea Basic Science Institute

Inventor： AHN, Yeong Hee ,  YOO, Jong Shin ,  KIM, Soohyun

IPC: C07H1/00

CPC classification number: C07H1/00

公开(公告)号：EP3900725A1

公开(公告)日：2021-10-27

申请号：EP19899095.4

申请日：2019-12-19

Applicant: Korea Basic Science Institute

Inventor： KIM, Gun Hwa ,  LEE, Min Ji ,  KIM, Koon Soon ,  CHUNG, Hyo Kyun ,  LEE, Ji Hoon ,  JUNG, Se Jin ,  KIM, Da Rong

IPC: A61K31/496 ,  A61P3/10 ,  A61P1/16 ,  A23L33/10

Abstract: The present invention relates to a composition comprising a CYP4A-inhibiting compound as an active ingredient for preventing or treating metabolic diseases, more specifically to a composition comprising the compound expressed by chemical formula 1 of the present invention or pharmaceutically acceptable salt thereof as an active ingredient for preventing, ameliorating or treating metabolic diseases.

公开(公告)号：EP3322263B1

公开(公告)日：2020-03-25

申请号：EP17200087.9

申请日：2017-11-06

Applicant: Korea Basic Science Institute

Inventor： YOU, Hyun Jong

IPC: H05H1/46

公开(公告)号：EP3255960A1

公开(公告)日：2017-12-13

申请号：EP16746881.8

申请日：2016-02-05

Applicant: Korea Basic Science Institute

Inventor： SEOK, Dong Chan ,  JUNG, Yong Ho ,  CHOI, Yong Sup ,  LHO, Taihyeop ,  LEE, Kang Il ,  JEONG, Hyun Young

IPC: H05H1/24 ,  H05H1/34

CPC classification number: H05H1/24 ,  H05H1/34

Abstract: The present invention is to provide a plasma-generating source including a porous dielectric member partially immersed in liquid into a plasma generation region between two opposite electrodes for generating dielectric barrier discharge plasma, such that generation of ozone and nitrogen oxides is suppressed while generation of hydroxy radicals is promoted.

Abstract translation: 本发明提供一种等离子体发生源，其包括部分浸入液体中的多孔电介质构件，进入两个相对电极之间的等离子体产生区，用于产生电介质阻挡放电等离子体，从而抑制臭氧和氮氧化物的产生，同时产生羟基 自由基得到促进。

公开(公告)号：EP2843433A1

公开(公告)日：2015-03-04

申请号：EP12888453.3

申请日：2012-11-16

Applicant: Korea Basic Science Institute

Inventor： PARK, Seung Young ,  KIM, Sang Il

IPC: G01R33/02

CPC classification number: G01R33/1284 ,  G01R33/0064

Abstract: The present invention is directed to a magnetic sensor using a spin transfer torque device, including a spin transfer torque device configured such that the magnetization direction thereof is varied by current, a bipolar pulse source configured to apply bipolar pulses to the spin transfer torque device in order to control the coercive field and sensitivity of the spin transfer torque device, and a signal processing unit configured to calculate magnetic susceptibility or magnetic resistance by counting the parallel (P) or anti-parallel (AP) states of the spin transfer torque device in response to the applied bipolar pulses.

Abstract translation: 本发明涉及一种使用自旋转移力矩装置的磁性传感器，该自旋转移力矩装置包括配置为使得其磁化方向随电流而变化的自旋转移力矩装置，配置成将双极性脉冲施加到自旋转移力矩装置中的双极性脉冲源 为了控制自旋转移力矩装置的矫顽磁场和灵敏度，以及信号处理单元，被配置为通过对自旋转移力矩装置的平行（P）或反平行（AP）状态进行计数来计算磁化率或磁阻 对应用的双极脉冲的响应。

公开(公告)号：EP2738554A1

公开(公告)日：2014-06-04

申请号：EP13814404.3

申请日：2013-01-22

Applicant: Korea Basic Science Institute

Inventor： PARK, Gun Wook ,  YOO, Jong Shin ,  KIM, Jin Young ,  LEE, Ju Yeon ,  LEE, Hyun Kyoung ,  AN, Hyun Joo ,  KIM, Jae-Han

IPC: G01N30/72 ,  G01N33/68 ,  C12Q1/34 ,  G06F17/10

CPC classification number: G06F19/16 ,  C12Q1/37 ,  G01N30/86 ,  G01N33/6848 ,  G01N2030/8813 ,  G01N2030/8831 ,  G01N2400/00 ,  G01N2440/38 ,  G01N2560/00 ,  G01N2570/00 ,  H01J49/0027 ,  H01J49/0036 ,  H01J49/004

Abstract: The present invention relates to a more efficient and accurate method for the identification and quantification of comparatively low abundant glycopeptides, compared with general peptides, using mass spectrum obtained by using high resolution mass spectrometer. Therefore, the method of the present invention can be effectively used for the techniques for identification of biotherapeutics and diagnosis of cancer or disease by screening glycopeptide, the disease marker (Biomarker), from various samples.

Abstract translation: 本发明涉及使用通过使用高分辨率质谱仪获得的质谱，与一般肽相比，用于鉴定和定量相对低丰度糖肽的更有效和准确的方法。 因此，通过从各种样品中筛选糖肽（疾病标记物（Biomarker）），本发明的方法可以有效地用于识别生物治疗剂和癌症或疾病的诊断技术。

公开(公告)号：EP2720518A2

公开(公告)日：2014-04-16

申请号：EP12797155.4

申请日：2012-06-01

Applicant: Korea Basic Science Institute

Inventor： YOO, Suk Jae ,  KIM, Seong Bong

IPC: H05H1/34 ,  H01L21/205 ,  C23C16/50

CPC classification number: H01J37/32669 ,  C23C14/354 ,  C23C14/357 ,  C23C14/54 ,  H01J37/32192 ,  H01J37/3266 ,  H01J37/34 ,  H05H2001/4607

Abstract: The present invention is about plasma generation source and a thing that is in its application and it is for getting high quality thin film by generating even high density plasma in high vacuum and like this plasma generation source applying like this plasma generation source to sputtering system, neutral particle beam source, thin film deposition system combining sputtering system and neutral particle beam source,
According to the present invention, it generates plasma by using microwave through the microwave irradiating equipment and magnetic field by more than one pair of the belt type magnets and above goal can be accomplished maximizing plasma confinement effect by inducing electron returning trajectory in accordance with above continuous structure on belt type magnet.

Abstract translation: 本发明涉及等离子体发生源及其应用，并且是通过在高真空中产生均匀的高密度等离子体而获得高品质的薄膜，并且像这样的等离子体发生源像溅射系统一样， 中性粒子束源，组合溅射系统和中性粒子束源的薄膜沉积系统根据本发明，通过使用微波通过微波照射设备和磁场产生等离子体，通过多于一对的带式磁体及以上 可以通过根据带式磁体上的连续结构诱导电子返回轨迹来实现目标的最大化等离子体约束效应。

公开(公告)号：EP2519816A2

公开(公告)日：2012-11-07

申请号：EP10841161.2

申请日：2010-12-15

Applicant: Korea Basic Science Institute

Inventor： PARK, Kyu Hwan ,  KIM, Hyun Sik ,  KWON, Kyung Hoon ,  YOO, Jong Shin

IPC: G01N30/72 ,  G01N33/15 ,  B01D15/08

CPC classification number: G01N30/06 ,  G01N30/8686 ,  G01N30/96 ,  G01N33/6848 ,  G01N2030/8809 ,  G01N2030/8813 ,  G01N2500/00 ,  Y10T436/174614 ,  Y10T436/24 ,  Y10T436/25 ,  Y10T436/25375

Abstract: Disclosed is a method for discovering pharmacologically active substances from natural products at high speed, including: obtaining an activity profile by testing pharmacological activity of a plurality of samples; obtaining a mass profile based on a mass spectrum resulting from analysis of the samples by mass spectrometry; and determining molecular weight of pharmacologically active substances by comparing and analyzing the activity profile and the mass profile. The disclosed method allows fast discovery of pharmacologically active substances by performing high resolution mass spectrometry for numerous components included in an extract sample of natural products and comparing with the activity test data. The information about the intensity of the activity of the pharmacologically active substances of the natural products allows effective utilization of the natural products.