-
公开(公告)号：NZ597823A
公开(公告)日：2014-05-30
申请号：NZ59782310
申请日：2010-02-18
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER R , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO , ZLOKARNIK GREGOR , VAN GOOR FREDRICK F
Abstract: 597823 Disclosed herein are pharmaceutical compositions comprising a solid dispersion of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (compound 1) for use treating or lessening the severity of cystic fibrosis in a patient, and method of manufacturing said compositions. In a preferred embodiment the patient possesses a cystic fibrosis transmembrane receptor (CFTR) with a &Dgr;F508 mutation or G551D mutation on both alleles.
-
公开(公告)号：HK1161140A1
公开(公告)日：2012-08-24
申请号：HK12102076
申请日：2012-02-29
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO
IPC: A61K20060101
Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
-
公开(公告)号：CA2769695A1
公开(公告)日：2011-02-17
申请号：CA2769695
申请日：2010-02-18
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER R , DINEHART KIRK , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO , ZLOKARNIK GREGOR , VAN GOOR FREDRICK F , VERWIJS MARINUS JACOBUS
Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis( 1, 1 -dimethylethyl)-5-hydroxyphenyl]- 1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
-
公开(公告)号：CA2569310A1
公开(公告)日：2005-12-29
申请号：CA2569310
申请日：2005-06-08
Applicant: VERTEX PHARMA
Inventor： HURTER PATRICIA , CUI YONG , CONNELLY PATRICK , MURPHY MAURA , DINEHART KIRK
Abstract: Forms and formulations of VX-950 and uses thereof.
-
公开(公告)号：CO2025001274A2
公开(公告)日：2025-02-13
申请号：CO2025001274
申请日：2025-02-04
Applicant: VERTEX PHARMA
Inventor： DINEHART KIRK , TIPS LAUREN BAILEY , METZLER CATHERINE , MCCARTY KATIE
IPC: A61K9/16 , A61K9/14 , A61K9/20 , A61K31/404 , A61K31/4439 , A61K31/47 , A61P11/00
Abstract: La presente invención se refiere a composiciones farmacéuticas que contienen N-(1,3-dimetilpirazol-4-il)sulfonil-6-[3-(3,3,3-trifluoro-2,2-dimetil-propoxi)pirazol-1-il]-2-[(4S)-2,2,4-trimetilpirrolidin-1-il]piridin-3-carboxamida, una dispersión sólida de (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-il)-N-(1-(2,3-dihidroxipropil)-6-fluoro-2-(1-hidroxi-2-metilpropan-2-il)-1H-indol-5-il)ciclopropanocarboxamida, y una dispersión sólida de N-[2,4-bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-dihidro-4-oxoquinolin-3-carboxamida que incluyen formulaciones de las dispersiones sólidas en polvos, gránulos y minitabletas, métodos para fabricar y procesar los polvos, gránulos y minitabletas, y métodos para tratar la fibrosis quística mediante el empleo de las composiciones farmacéuticas.
-
Patent Agency Ranking
公开(公告)号：PL3345625T3
公开(公告)日：2021-06-14
申请号：PL17204189
申请日：2009-08-13
Applicant: VERTEX PHARMA
-
公开(公告)号：RS61408B1
公开(公告)日：2021-03-31
申请号：RSP20210129
申请日：2009-08-13
Applicant: VERTEX PHARMA
-
公开(公告)号：RS58604B1
公开(公告)日：2019-05-31
申请号：RSP20190432
申请日：2010-02-18
Applicant: VERTEX PHARMA
-
公开(公告)号：DK2464337T3
公开(公告)日：2019-04-23
申请号：DK10708442
申请日：2010-02-18
Applicant: VERTEX PHARMA
-
公开(公告)号：SI2328618T1
公开(公告)日：2018-04-30
申请号：SI200931803
申请日：2009-08-13
Applicant: VERTEX PHARMA
-
-
-
-
-
-
-
-
-
Search Results
70
records
(took 0.021 seconds)
