公开(公告)号：DE10209446A1

公开(公告)日：2003-09-18

申请号：DE10209446

申请日：2002-03-05

Applicant: BASF AG

Inventor： KINDLER ALOIS ,  HENKELMANN JOCHEM ,  BECKER MICHAEL ,  RUST HARALD ,  KNOLL CHRISTIAN ,  BURKART KIRSTEN

IPC: B01D3/14 ,  B01J14/00 ,  C07D213/67 ,  C07D263/42 ,  C07B37/12

Abstract: Production of 5-alkoxy oxazoles (I) comprises heating an alkyl alpha-isocyanoalkanoate ester (II) at a temperature above 80 degreesC in the presence of an auxiliary agent and simultaneously separating the product from the reaction mixture. Production of 5-alkoxy oxazoles of formula (I) comprises heating an alkyl alpha-isocyanoalkanoate ester of formula (II) at a temperature above 80 degreesC in the presence of an auxiliary agent and simultaneously separating the product from the reaction mixture. R1 = optionally substituted 1-6C alkyl; R2 = H or optionally substituted 1-6C alkyl. An Independent claim is also included for a process for producing pyridoxine derivatives of formula (IX), comprising: (1) converting an amino acid of formula (III) to an ester of formula (IV); (2) converting (IV) to a formamido ester of formula (IV); (3) converting (IV) to (II), converting (II) to (I) as above; (4) reacting (I) with a protected diol of formula (VI) to form a Diels-Alder adduct of formula (VII); and (5) converting (VII) to (IX) by acid treatment and deprotection. R3, R4 = protecting groups or together form a protecting group.

公开(公告)号：AU2003223951A1

公开(公告)日：2003-09-16

申请号：AU2003223951

申请日：2003-02-28

Applicant: BASF AG

Inventor： BURKART KIRSTEN ,  KINDLER ALOIS ,  HENKELMANN JOCHEM ,  BECKER MICHAEL ,  RUST HARALD ,  KNOLL CHRISTIAN

IPC: C07D263/42

公开(公告)号：ES2190243T3

公开(公告)日：2003-07-16

申请号：ES99941607

申请日：1999-08-13

Applicant: BASF AG

Inventor： KINDLER ALOIS ,  BRUNNER MELANIE ,  TRAGUT CHRISTIAN ,  HENKELMANN JOCHEM

IPC: C07B61/00 ,  C07C29/42 ,  C07C33/044

Abstract: The invention relates to a method for producing alkyne diols by reacting ketones with acetylenic hydrocarbons in an organic solvent in the presence of a base which contains potassium alcoholates of primary and/or secondary alcohols. The alkyne diols are produced while forming adducts which precipitate out of the reaction mixture and which are comprised of alkyne monoalcohols and/or alkyne diols and a base. The stoichiometries of the reaction partners are selected such that gelatinous adducts are formed which comprise a spherical surface, whereby the reaction mixture remains agitable during the entire reaction.

公开(公告)号：DE10137480A1

公开(公告)日：2003-02-13

申请号：DE10137480

申请日：2001-08-03

Applicant: BASF AG

Inventor： RUST HARALD ,  BURKART KIRSTEN ,  FAUST TILLMANN ,  HENKELMANN JOCHEM ,  KINDLER ALOIS ,  KNOLL CHRISTIAN

IPC: C07D233/70 ,  C07D213/67 ,  C07D263/42 ,  C07D213/66

Abstract: Production of 5-alkoxy oxazoles (I) comprises heating an alkyl alpha -isocyanoalkanoate ester (II) at a temperature above 80 deg C in the presence of an auxiliary agent and simultaneously separating the product from the reaction mixture. Production of 5-alkoxy oxazoles of formula (I) comprises heating an alkyl alpha -isocyanoalkanoate ester of formula (II) at a temperature above 80 deg C in the presence of an auxiliary agent and simultaneously separating the product from the reaction mixture. R1 = optionally substituted 1-6C alkyl; R2 = H or optionally substituted 1-6C alkyl. An Independent claim is also included for a process for producing pyridoxine derivatives of formula (IX), comprising: (1) converting an amino acid of formula (III) to an ester of formula (IV); (2) converting (IV) to a formamido ester of formula (IV); (3) converting (IV) to (II), converting (II) to (I) as above; (4) reacting (I) with a protected diol of formula (VI) to form a Diels-Alder adduct of formula (VII); and (5) converting (VII) to (IX) by acid treatment and deprotection. R3, R4 = protecting groups or together form a protecting group.

公开(公告)号：AU8438998A

公开(公告)日：1999-01-25

申请号：AU8438998

申请日：1998-06-29

Applicant: BASF AG

Inventor： KNOLL KONRAD ,  KINDLER ALOIS ,  FISCHER WOLFGANG

IPC: C08L53/00 ,  C08C19/44 ,  C08F4/00 ,  C08F297/00 ,  C08F297/02 ,  C08F297/04 ,  C08G81/02

Abstract: New oximsulfonate compounds of formulae (I) or (II), wherein m is 0 or 1; x is 1 or 2; R1 is, for example phenyl, which is unsubstituted or substituted or R1 is a heteroaryl radical that is unsubstituted or substituted, or, if m is 0, R1 additionally is C2-C6alkoxycarbonyl, phenoxycarbonyl or CN; R'1 is for example C2-C12alkylene, phenylene; R2 has for example one of the meanings of R1; n is 1 or 2; R3 is for example C1-C18alkyl, R'3 when x is 1, has one of the meanings given for R3, or R'3 in formula (IV) and when x is 2 in formula (I), is for example C2-C12 alkylene, phenylene; R4 and R5 are independently of each other for example hydrogen, halogen, C1-C6alkyl; R6 is for example hydrogen, phenyl; R7 and R8 are independently of each other for example hydrogen or C1-C12alkyl; R9 is for example C1-C12alkyl; A is S, O, NR6, or a group of formula (A1), (A2), (A3) or (A4); R10 and R11 independently of each other have one of the meanings given for R4; R12, R13, R14 and R15 independently of one another are for example hydrogen, C1-C4alkyl; Z is CR11 or N; Z1 is -CH2-, S, O or NR6, are useful as latent sulfonic acids, especially in photoresist applications.

公开(公告)号：CA2340697C

公开(公告)日：2009-03-31

申请号：CA2340697

申请日：1999-08-13

Applicant: BASF AG

Inventor： HENKELMANN JOCHEM ,  KINDLER ALOIS ,  BRUNNER MELANIE ,  TRAGUT CHRISTIAN

IPC: C07C29/42 ,  C07B61/00 ,  C07C33/044

Abstract: The invention relates to a method for producing alkyne diols by reacting ketones with acetylenic hydrocarbons in an organic solvent in the presence of a base which contains potassium alcoholates of primary and/or secondary alcohols. The alkyne diols are produced while forming adducts which precipitate out of the reaction mixture and which are comprised of alkyne monoalcohols and/or alkyne diols and a base. The stoichiometries of the reaction partners are selected such that gelatinous adducts are formed which comprise a spherical surface, whereby the reaction mixture remains agitable during the entire reaction.

公开(公告)号：DE50308134D1

公开(公告)日：2007-10-18

申请号：DE50308134

申请日：2003-10-28

Applicant: BASF AG

Inventor： DOBLER WALTER ,  BAHR NICOLAUS ,  BREUER KLAUS ,  KINDLER ALOIS

IPC: C07C45/54 ,  C07C45/74 ,  C07C49/203 ,  C07C403/16

Abstract: The invention relates to a continuous process for producing pseudoionones of general formulas (I) and (I') as well as isomers thereof, whereby: R 1 represents CH 3 or (a); R 2 and R 3 represent hydrogen, CH 3 or C 2 H 5 , and; R 4 and R 5 represent hydrogen or CH 3 . These pseudoionones are produced by reacting an aldehyde of formula (II) with an excess of a ketone of general formula (III), whereby R 1 , R 2 and R 3 have the aforementioned meanings, in the presence of water and alkali hydroxide at an increased temperature and in a homogeneous solution. The inventive process is characterized in that: a) the intermixing of the homogeneous solution consisting of aldehyde, ketone and aqueous alkali lye occurs at a temperature ranging from 10 to 120° C.; b) the undissolved water and alkali hydroxide contained in the reaction mixture are subsequently separated out; c) while avoiding back mixing, the homogeneous reaction mixture is then guided through a reactor, which permits a residence time ranging from 2 to 300 minutes, at a temperature that is 10 to 120° C. higher than the boiling point of the lowest-boiling component and under a vapor pressure p ranging from 10 6 to 10 7 Pa; d) the reaction mixture is cooled by expansion; e) ketone is removed from the reaction mixture using vapor flowing in the opposite direction and; f) the raw product is dried and rid from excessive aldehyde and secondary components via a rectification column.

公开(公告)号：AU2003300226A1

公开(公告)日：2004-07-22

申请号：AU2003300226

申请日：2003-12-23

Applicant: BASF AG

Inventor： KINDLER ALOIS ,  LETZELTER THOMAS ,  FRANKE DIRK ,  FRIESE KATRIN ,  KNOLL CHRISTIAN

IPC: C07D213/67 ,  C07D498/08 ,  C07D498/18

公开(公告)号：AU2003254574A1

公开(公告)日：2004-03-11

申请号：AU2003254574

申请日：2003-07-23

Applicant: BASF AG

Inventor： ARNDT JAN-DIRK ,  KLASS KATRIN ,  HENKELMANN JOCHEM ,  KINDLER ALOIS

IPC: C07B61/00 ,  C07C29/42 ,  C07C33/042 ,  C07C33/048 ,  C07C33/14 ,  C07C33/48 ,  C07C403/00

公开(公告)号：DE59903919D1

公开(公告)日：2003-02-06

申请号：DE59903919

申请日：1999-08-13

Applicant: BASF AG

Inventor： KINDLER ALOIS ,  BRUNNER MELANIE ,  TRAGUT CHRISTIAN ,  HENKELMANN JOCHEM

IPC: C07B61/00 ,  C07C29/42 ,  C07C33/044

Abstract: The invention relates to a method for producing alkyne diols by reacting ketones with acetylenic hydrocarbons in an organic solvent in the presence of a base which contains potassium alcoholates of primary and/or secondary alcohols. The alkyne diols are produced while forming adducts which precipitate out of the reaction mixture and which are comprised of alkyne monoalcohols and/or alkyne diols and a base. The stoichiometries of the reaction partners are selected such that gelatinous adducts are formed which comprise a spherical surface, whereby the reaction mixture remains agitable during the entire reaction.