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    33.
    发明专利
    未知

    公开(公告)号：NO312333B1

    公开(公告)日：2002-04-29

    申请号：NO991527

    申请日：1999-03-29

    Applicant: BASF AG

    Inventor： NIESSNER MANFRED ,  NILZ CLAUDIA ,  HOESSEL PETER ,  KOTHRADE STEPHAN ,  SANNER AXEL

    IPC: A61K8/00 ,  A61K8/36 ,  A61K8/42 ,  A61K8/49 ,  A61K8/72 ,  A61K8/81 ,  A61K8/898 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/04 ,  A61Q5/10 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  C08F226/02 ,  C08F226/06 ,  A61K7/48

    Abstract: A cosmetic composition comprising water-soluble copolymer, which as characteristic structural elements comprisesa) vinylcarboxamide units of the general formula IwhereR1 and R2 independently of one another are H, alkyl, cycloalkyl, aryl or aralkyl, andb) units of the general formula IIwhereA is a chemical bond or an alkylene group,the radicals R3 independently of one another are H, alkyl, cycloalkyl, aryl or aralkyl, or together with the nitrogen atom to which they are bonded, form an unsubstituted, mono- or polysubstituted, five- to seven-membered, heterocyclic, aromatic or nonaromatic ring, which if appropriate contains one or two further heteroatoms, selected from among O, N and S, it being possible for the heterocyclic ring to be fused to a further five- or six-membered, aromatic or nonaromatic ring,R4 is H, alkyl or aralkyl.

    Solid dosage form for prolonged slow release of e.g. drugs, plant treatment agents, or food or feed additives, containing copolymer of N-vinyl-lactam, methyl methacrylate and further monomer(s) as binder
    34.
    发明专利
    Solid dosage form for prolonged slow release of e.g. drugs, plant treatment agents, or food or feed additives, containing copolymer of N-vinyl-lactam, methyl methacrylate and further monomer(s) as binder 未知

    公开(公告)号：DE19843904A1

    公开(公告)日：2000-03-30

    申请号：DE19843904

    申请日：1998-09-24

    Applicant: BASF AG

    Inventor： KOTHRADE STEPHAN ,  BERNDL GUNTHER ,  MEFFERT HELMUT

    IPC: A61K9/20 ,  A61K9/22 ,  A61K9/32 ,  A61K9/42

    Abstract: A solid dosage form contains a copolymer of an N-vinyl-lactam, methyl methacrylate, an ester or acid derivative monomer and optionally an acid monomer, as polymeric binder. A solid dosage form comprises least one polymeric binder, at least one active agent (A) and optionally conventional additives, where the binder is a copolymer of: (a) at least one N-vinyl-lactam of formula (I) (15-83 wt. %); (b) methyl methacrylate (15-83 wt. %); (c) at least one monomer (2-70 wt. %) selected from vinyl esters of 1-22C aliphatic carboxylic acids, esters of 3-8C alpha , beta -ethylenically unsaturated mono- or dicarboxylic acids with 1-8C alkanols, 1-4C diols or di-(1-4C alkyl)-amino-(1-4C) alkanols and amides, nitriles or cyclic anhydrides of these acids; and (d) at least one alpha , beta -ethylenically unsaturated acid (0-9.9 wt. %) selected from 3-8C alpha , beta -ethylenically unsaturated mono- or dicarboxylic acids, their non-cyclic anhydrides, hemi-esters of the dicarboxylic acids and alpha , beta -ethylenically unsaturated sulfonic acids (including salts or quaternized derivatives). n = 1-3. An Independent claim is included for the preparation of the dosage form, by mixing the components (directly or after preliminary melting) and shaping the obtained plastic mixture into the required dosage form.

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