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31.
公开(公告)号:AU2020201314A1
公开(公告)日:2020-03-12
申请号:AU2020201314
申请日:2020-02-21
Applicant: VERTEX PHARMA
Inventor: HURTER PATRICIA , CONNELLY PATRICK , ROWE WILLIAM , YOUNG CHRISTOPHER R , COSTACHE ADRIANA , KRAWIEC MARIUSZ , GONG YUCHUAN , FENG YUSHI , TRUDEAU MARTIN
IPC: A61K31/445
Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5 hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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公开(公告)号:RS58604B1
公开(公告)日:2019-05-31
申请号:RSP20190432
申请日:2010-02-18
Applicant: VERTEX PHARMA
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公开(公告)号:DK2464337T3
公开(公告)日:2019-04-23
申请号:DK10708442
申请日:2010-02-18
Applicant: VERTEX PHARMA
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34.
公开(公告)号:AU2018204203A1
公开(公告)日:2018-07-05
申请号:AU2018204203
申请日:2018-06-13
Applicant: VERTEX PHARMA
Inventor: HURTER PATRICIA , CONNELLY PATRICK , ROWE WILLIAM , YOUNG CHRISTOPHER R , COSTACHE ADRIANA , KRAWIEC MARIUSZ , GONG YUCHUAN , FENG YUSHI , TRUDEAU MARTIN
IPC: A61K31/445
Abstract: The present invention relates to solid state forms of N-[2,4-bis(1 ,1 -dimethylethyl)-5 hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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公开(公告)号:SI2328618T1
公开(公告)日:2018-04-30
申请号:SI200931803
申请日:2009-08-13
Applicant: VERTEX PHARMA
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公开(公告)号:DK2328618T3
公开(公告)日:2018-02-19
申请号:DK09789125
申请日:2009-08-13
Applicant: VERTEX PHARMA
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37.
公开(公告)号:HUE032813T2
公开(公告)日:2017-11-28
申请号:HUE06848237
申请日:2006-12-28
Applicant: VERTEX PHARMA
Inventor: HURTER PATRICIA , GONG YUCHUAN , YOUNG CHRISTOPHER R , CONNELLY PATRICK , ROWE WILLIAM , COSTACHE ADRIANA , KRAWIEC MARIUSZ , FENG YUSHI , TRUDEAU MARTIN
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38.
公开(公告)号:PL1993360T3
公开(公告)日:2017-08-31
申请号:PL06848237
申请日:2006-12-28
Applicant: VERTEX PHARMA
Inventor: HURTER PATRICIA , GONG YUCHUAN , YOUNG CHRISTOPHER R , CONNELLY PATRICK , ROWE WILLIAM , COSTACHE ADRIANA , KRAWIEC MARIUSZ , FENG YUSHI , TRUDEAU MARTIN
IPC: C07D215/56 , A61K31/445
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39.
公开(公告)号:AU2016219571A1
公开(公告)日:2016-09-08
申请号:AU2016219571
申请日:2016-08-23
Applicant: VERTEX PHARMA
Inventor: HURTER PATRICIA , CONNELLY PATRICK , ROWE WILLIAM , YOUNG CHRISTOPHER R , COSTACHE ADRIANA , KRAWIEC MARIUSZ , GONG YUCHUAN , FENG YUSHI , TRUDEAU MARTIN
IPC: A61K31/445
Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1 -dimethylethyl)-5 hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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公开(公告)号:AU2016216569A1
公开(公告)日:2016-09-01
申请号:AU2016216569
申请日:2016-08-16
Applicant: VERTEX PHARMA
Inventor: ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO , VERWIJS MARINUS JACOBUS
IPC: A61K47/32
Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3 carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
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