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公开(公告)号：KR1020130109587A
公开(公告)日：2013-10-08
申请号：KR1020120031444
申请日：2012-03-28
Applicant: 목포대학교산학협력단
IPC: A61K31/357 , A61K31/045 , A61K31/01 , A61P9/12
Abstract: PURPOSE: A composition for preventing or treating hypertension is provided to suppress NO generation and epoxide hydrolase, thereby preventing or treating cardiovascular diseases with safety. CONSTITUTION: A pharmaceutical composition for preventing or treating cardiovascular diseases contains one of a compound of chemical formula 1 and a compound of chemical formula 2 or a pharmaceutically acceptable salt thereof as an active ingredient. The cardiovascular diseases are hypertension or hypertensive heart diseases. A composition for suppressing epoxide hydrolase contains one of the compound of chemical formula 1 and the compound of chemical formula 2 or a pharmaceutically acceptable salt thereof as an active ingredient. Epoxy hydrolase is soluble.
Abstract translation: 目的：提供用于预防或治疗高血压的组合物，以抑制NO产生和环氧化物水解酶，从而安全地预防或治疗心血管疾病。 构成：用于预防或治疗心血管疾病的药物组合物含有化学式1的化合物和化学式2的化合物或其药学上可接受的盐作为活性成分之一。 心血管疾病是高血压或高血压性心脏病。 用于抑制环氧化物水解酶的组合物含有化学式1化合物和化学式2化合物或其药学上可接受的盐之一作为活性成分。 环氧水解酶是可溶的。
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公开(公告)号：KR1020130099771A
公开(公告)日：2013-09-06
申请号：KR1020120021519
申请日：2012-02-29
Applicant: 목포대학교산학협력단
CPC classification number: A23L33/00
Abstract: PURPOSE: A food composition for preventing or treating hypertension is provided to offer a blood pressure decreasing effect, and to effectively inhibit water-soluble epoxide hydrolase. CONSTITUTION: A food composition for preventing or treating cardiovascular diseases contains a Nardostachys chinensis extract as an active ingredient. The cardiovascular diseases are hypertension or hypertensive heart disease. The Nardostachys chinensis extract is extracted by using more than one extracting solvent selected from water, 50-100% alcohol with 1-5 carbons, ethyl acetate, hexane, chloroform, methylene chloride, and dichloromethane. The Nardostachys chinensis extract is extracted by methanol. The Nardostachys chinensis extract is fractioned by more than one fraction solvent selected from water, 50-100% alcohol with 1-5 carbons, ethyl acetate, hexane, chloroform, methylene chloride, and dichloromethane. The Nardostachys chinensis extract is extracted by methanol, and fractioned by hexane.
Abstract translation: 目的：提供预防或治疗高血压的食物组合物，以提供降血压作用，并有效抑制水溶性环氧化物水解酶。 构成：用于预防或治疗心血管疾病的食物组合物含有作为活性成分的天竺葵提取物。 心血管疾病是高血压或高血压性心脏病。 通过使用选自水，50-100％的醇，1-5个碳原子，乙酸乙酯，己烷，氯仿，二氯甲烷和二氯甲烷中的多种提取溶剂萃取中华提取物。 中药提取物采用甲醇萃取。 通过多于一种选自水，50-100％的醇，1-5个碳原子，乙酸乙酯，己烷，氯仿，二氯甲烷和二氯甲烷的级分溶剂分离出Nardostachys chinensis提取物。 中药提取物用甲醇萃取，用己烷分馏。
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公开(公告)号：KR1020120049459A
公开(公告)日：2012-05-17
申请号：KR1020100110697
申请日：2010-11-09
Applicant: 목포대학교산학협력단
Abstract: PURPOSE: A producing method of green tea having skin condition improving functions is provided to improve an anti-wrinkle effect, a UV-screening effect, and a skin moisturizing effect of the green tea. CONSTITUTION: A producing method of green tea having skin condition improving functions comprises the following steps: grinding tea tree stems in acetone; filtering the ground tea tree stems to obtain residues to obtain a functionality enhancing composition; reacting the functionality enhancing composition with conventional green tea for 4 hours 30 minutes-7 hours 30 minutes in a reaction solvent at the pH of 5-7; extracting steam from the green tea by heating the green tea with distilled water; and adding an organic solvent containing n-pentane, diethyl ether, and ethanol to the steam for obtaining a substance having the elastase inhibiting activity, and concentrating the substance using a chromatography method.
Abstract translation: 目的：提供具有皮肤状况改善功能的绿茶的制造方法，以提高绿茶的抗皱效果，紫外线遮蔽效果和皮肤保湿效果。 构成：具有皮肤状况改善功能的绿茶的生产方法包括以下步骤：在丙酮中研磨茶树茎; 过滤研磨茶树茎以获得残留物以获得增强功能的组合物; 使功能增强组合物与常规绿茶反应4小时30分钟-7小时30分钟在反应溶剂中，pH为5-7; 用蒸馏水加热绿茶，从绿茶中提取蒸汽; 并向蒸汽中加入含有正戊烷，乙醚和乙醇的有机溶剂，得到具有弹性蛋白酶抑制活性的物质，并使用色谱法浓缩该物质。
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公开(公告)号：KR101021481B1
公开(公告)日：2011-03-16
申请号：KR1020090105819
申请日：2009-11-04
Applicant: 목포대학교산학협력단
IPC: C12G1/022
CPC classification number: C12G1/0203 , C12G2200/05 , C12G2200/21
Abstract: PURPOSE: A method for producing green tea white wine is provided to ensure functionality and to improve preference under optimal condition. CONSTITUTION: A method for producing green tea white wine comprises: a step of crushing and pressing green grapes to obtain grape juice; a step of inoculating fermentation strain to the grape juice; a step of fermenting the grape juice to obtain a primary fermentation; a step of adding dried green tea into the primary fermentation; and a step of secondarily fermenting. The fermentation strain is Saccharomyces cerevisiae KCCM 11351, Saccharomyces cerevisiae KCCM 12224, Saccharomyces bayanus KCCM 12633, and Saccharomyces pastorianus KCCM 32361.
Abstract translation: 目的：提供一种生产绿茶白葡萄酒的方法，以确保最佳条件下的功能和改善偏好。 构成：生产绿茶白葡萄酒的方法包括：将绿色葡萄粉碎和压榨获得葡萄汁的步骤; 向葡萄汁接种发酵菌株的步骤; 发酵葡萄汁以获得初级发酵的步骤; 将干绿茶加入初级发酵的步骤; 和二次发酵的步骤。 发酵菌株是酿酒酵母KCCM11351，酿酒酵母KCCM 12224，酿酒酵母KCCM 12633和巴斯德毕赤酵母KCCM 32361。
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公开(公告)号：KR1020110002392A
公开(公告)日：2011-01-07
申请号：KR1020090059980
申请日：2009-07-01
Applicant: 목포대학교산학협력단
CPC classification number: A23L2/52 , A23L2/38 , A23L33/105 , A23V2002/00 , A23V2250/21
Abstract: PURPOSE: A sport beverage composition containing a salicornia herbacia extract is provided to improve the exercise ability and the endurance capacity of a drinker without causing a side effect. CONSTITUTION: A sport beverage composition contains a salicornia herbacia extract as an active ingredient. The salicornia herbacia extract is obtained by a method selected from the group consisting of a hydrothermal extraction method, a solvent extraction method, a sonicate-extraction method, and a water-immersion extraction method. The salicornia herbacia extract is diluted with water in a ratio of 1:15~1:60, after being extracted.
Abstract translation: 目的：提供一种运动饮料组合物，其中含有海参茄子提取物，以提高饮酒者的运动能力和耐力，而不会引起副作用。 构成：运动饮料组合物含有作为活性成分的沙门氏菌提取物。 通过选自水热提取法，溶剂萃取法，超声波提取法和浸水萃取法的方法获得海参茄子提取物。 提取后，水分比为1：15〜1：60，用水稀释。
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Patent Agency Ranking
公开(公告)号：KR1020100003046A
公开(公告)日：2010-01-07
申请号：KR1020080063144
申请日：2008-06-30
Applicant: 목포대학교산학협력단
IPC: A61K33/14 , A61K36/605 , A61P31/04
Abstract: PURPOSE: An antibacterial composition containing sun dried salt and Cudrania tricuspidata extract as active ingredient is provided to ensure high antibacterial activity to Streptococcus mutans, prevent and treat dental caries. CONSTITUTION: An antibacterial composition to Streptococcus mutans contains salt and Cudrania tricuspidata extract as an active ingredient. The Cudrania tricuspidata extract is isolated using water, 50-100% of alcohol of 1-4 carbon atoms, ethylacetate, hexane or dichloromethane from stem, leave, roots, flower or fruits. Fraction is additionally performed using hexane, methylchloride, acetone, ethylacetae, ethylather, chloroform, water, and their mixture from the extract. A food composition for preventing or relieving dental carrier contains the antibacterial composition to Streptococcus mutans.
Abstract translation: 目的：提供含有太阳干燥盐和三头螨提取物作为活性成分的抗菌组合物，以确保对变形链球菌的高抗菌活性，预防和治疗龋齿。 构成：对变形链球菌的抗菌组合物含有盐和三趾提取物作为活性成分。 使用水，50-100％的1-4个碳原子的醇，乙酸乙酯，己烷或二氯甲烷从茎，叶，根，花或果实中分离出三头螨提取物。 使用己烷，甲基氯，丙酮，乙二乙酸乙酯，乙醚，氯仿，水及其萃取物的混合物进一步进行馏分。 用于预防或减轻牙齿载体的食品组合物含有变形链球菌的抗菌组合物。
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公开(公告)号：KR1020170085737A
公开(公告)日：2017-07-25
申请号：KR1020160005237
申请日：2016-01-15
Applicant: 목포대학교산학협력단
Abstract: 본발명은천년초추출물의발효물을유효성분으로포함하는항염조성물에관한것이다. 본발명의천년초추출물의발효물은식용으로사용되는식물및 가장안전한추출용매인수용매를이용한추출물을발효시킨발효물로서부작용이나안전성에대한문제가적고, 염증과관련된 NO의소거능과항산화활성이우수할뿐만아니라, 기존천년초의산업화에가장큰 장애인높은점도를해결하면서도오히려기능성이개선된다는것을확인한결과, 효과적으로항염효과를가진유효성분으로확인되었다. 따라서, 상기천년초추출물의발효물을유효성분으로포함하는항염조성물은염증을억제하여염증과관련된질병을치료또는예방하기위한항염증제및 특정제형등과관련하여화장품제조에필수적으로사용되는성분또는외부환경으로인한피부의염증을효과적으로억제할수 있는특징을갖는화장료조성물등에응용될수 있다.
Abstract translation: 本发明涉及含有海啸提取物的发酵物作为有效成分的消炎组合物。 副作用和本发明的提取物cheonnyeoncho的安全发酵少的问题提供了可用于使用植物和最安全的溶剂萃取因子溶剂的发酵产物发酵的提取物用于人类消费，以yiwoosu清扫和与炎症相关的NO的抗氧化活性 此外，同时解决现有cheonnyeoncho的最高粘度残疾人工业化而结果证实，功能改善得到有效确认为具有抗炎作用的活性成分。 因此，cheonnyeoncho的发酵产物提取包含与抗炎剂和部件是在连接作为化妆品制品基本上使用特定配方或通过抑制发炎用于治疗与炎症相关的疾病的治疗或预防的环境中的活性成分的抗炎组合物 并且可以应用于具有能够有效抑制由其引起的皮肤炎症的特征的化妆品组合物。
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公开(公告)号：KR101608270B1
公开(公告)日：2016-04-01
申请号：KR1020140024764
申请日：2014-02-28
Applicant: 목포대학교산학협력단
Abstract: 본발명은미생물발효차로부터분리된아스퍼질러스퓨미가터스 (.) 균주, 구체적으로미생물발효차로부터분리되고, 상기균주로발효시켜제조된발효차에기능성특히, 항비만활성을부여할수 있는균주아스퍼질러스퓨미가터스() 균주, 상기미생물발효차로부터분리된아스퍼질러스퓨미가터스() 균주, 상기균주의배양액및 상기배양액의농축액으로이루어지는군에서선택된 1종이상을포함하는미생물발효차제조용생촉매(biocatalyst) 및상기미생물발효차제조용생촉매를차나무잎과반응시키는단계를포함하는미생물발효차의제조방법에관한것이다. 상기미생물발효차로부터분리된신규한아스퍼질러스퓨미가터스균주는기존보고된미생물발효차로부터분리된미생물과비교하여, 상기미생물을이용하여제조된미생물발효차는다양한기능성, 구체적으로항비만활성이개선되므로, 품질이우수한미생물발효차의제조를위해사용될수 있다.
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公开(公告)号：KR3007935490000S
公开(公告)日：2015-04-22
申请号：KR3020140046798
申请日：2014-09-26
Applicant: 목포대학교산학협력단
Designer： 마승진
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