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公开(公告)号：KR101408840B1
公开(公告)日：2014-06-19
申请号：KR1020120126826
申请日：2012-11-09
Applicant: 한국화학연구원
CPC classification number: Y02P60/877
Abstract: 본 발명은 팜유의 제조 과정에서 부산물로 발생하는 과육 또는 이의 가수분해물을 이용하거나, 부원료를 추가로 혼합하여 탄수화물, 단백질 및 지방의 비율이 잘 조정된 농후사료로 전환할 수 있으므로, 팜유의 생산과정에서 지속적으로 생산되는 부산물을 고부가가치화할 수 있고, 폐기물을 획기적으로 줄이는 데 효과적이다.
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公开(公告)号：KR1020140060124A
公开(公告)日：2014-05-19
申请号：KR1020120126826
申请日：2012-11-09
Applicant: 한국화학연구원
CPC classification number: Y02P60/877 , A23K10/37 , A23K40/20
Abstract: The present invention uses pulp generated as by-products in a palm oil production process or hydrolysate thereof, or additionally mixes a supplementary material to convert to concentrate feed, which rates of carbohydrate, protein and fat are well adjusted. Therefore, high value can be added to the by-products continuously produced in the palm oil production process, and waste can be significantly reduced.
Abstract translation: 本发明使用在棕榈油生产方法或其水解产物中作为副产物产生的纸浆，或者另外混合补充材料以转化成浓缩饲料，其中碳水化合物，蛋白质和脂肪的速率被很好地调节。 因此，可以在棕榈油生产过程中连续生产的副产物中增加高价值，并且可以显着降低废物。
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公开(公告)号：KR101298135B1
公开(公告)日：2013-08-20
申请号：KR1020110067628
申请日：2011-07-08
Applicant: 한국화학연구원
Abstract: 본 발명은 주원료로서 리그노셀룰로오스계 바이오매스, 및 접착제로서 탈지된 단백질계 천연물질 또는 바이오매스의 당화 후 잔사로 남는 리그닌계 접착성 물질로 구성된 연료용 또는 사료용 펠릿 및 이의 제조방법에 관한 것으로, 본 발명에 따른 펠릿은 부식성 물질이나 유독성 연소 기체가 발생하지 않고, 제조가 용이하며, 열량이 높고, 접착제를 사용하여 종래 목질 펠렛에 비해 높은 강도를 가지므로, 연료용, 사료용 또는 애완동물의 놀이용 또는 침대 재료로 유용하게 사용될 수 있다.
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54.发明公开작약 종자 추출물, 이의 분획물 또는 이로부터 분리한 화합물을 유효성분으로 함유하는 퇴행성 뇌질환 예방 또는 치료용 약학적 조성물 有权包含提取物的活性成分的药物组合物，其分离物或其分离的化合物作为活性成分
公开(公告)号：KR1020120016861A
公开(公告)日：2012-02-27
申请号：KR1020100079356
申请日：2010-08-17
Applicant: 한국화학연구원
IPC: A61K36/65 , A61K31/343 , A61P25/28 , A61P25/00
CPC classification number: A61K36/65 , A23L29/035 , A23V2200/322 , A61K31/216 , A61K31/343 , A61K2236/33
Abstract: PURPOSE: A pharmaceutical composition containing Paeonia lactiflora seed extract, fraction thereof, or compound isolated from the same is provided to suppress BACE-1 activity and to treat and prevent neurodegenerative diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating neurodegenerative diseases contains Paeonia lactiflora seed extract as an active ingredient. The neurodegenerative diseases include Alzheimer's dieses, Parkinsons's disease, progressive supranuclear palsy. The extract is prepared using water, alcohol of C1-C4, or mixture solvent thereof. The pharmaceutical composition contains Paeonia lactiflora seed fraction as an active ingredient. The pharmaceutical composition also contains compounds as an active ingredient. The method for preparing the compounds comprises: a step of adding water, C1-C3 alcohol, or mixture thereof to the Paeonia lactiflora seeds to prepare Paeonia lactiflora seed extract; a step of fractioning the extract with water, dichloromethane, and ethyl acetate to prepare a fraction; a step of performing silicagel column chromatography of the fraction.
Abstract translation: 目的：提供含有芍药提取物，其部分或从其分离的化合物的药物组合物以抑制BACE-1活性并治疗和预防神经变性疾病。 构成：用于预防或治疗神经变性疾病的药物组合物含有芍药种子提取物作为活性成分。 神经变性疾病包括阿尔茨海默氏病，帕金森氏病，进行性核上性麻痹。 萃取液用水，C1-C4的醇或其混合溶剂制备。 该药物组合物含有作为活性成分的芍药芍药种子。 药物组合物还含有作为活性成分的化合物。 制备化合物的方法包括：将水，C1-C3醇或其混合物加入到芍药种子中以制备芍药提取物的步骤; 用水，二氯甲烷和乙酸乙酯分级提取物以制备级分的步骤; 进行该级分的硅胶柱色谱的步骤。
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公开(公告)号：KR100937394B1
公开(公告)日：2010-01-18
申请号：KR1020070132164
申请日：2007-12-17
IPC: A61K36/185 , A61P9/08 , A61P9/12
Abstract: 본 발명은 유백피(
Ulmus macrocarpa ) 추출물을 유효성분으로 함유하는 혈관 이완용 조성물에 관한 것으로서, 본 발명에 따른 조성물은 항산화 작용 및 혈관 평활근 이완 작용을 통해 우수한 혈압강하 효과를 나타내므로, 고혈압 및 고혈압의 합병증으로 인한 각종 심혈관계 질환의 예방 및 치료를 위한 약학 조성물 또는 건강기능 식품으로 유용하게 사용될 수 있다.-
Patent Agency Ranking56.发明公开포도나무 수피로부터 분리된 ＢＡＣＥ-1 저해 효과를 갖는활성물질을 포함하는 퇴행성 뇌질환의 예방 또는 치료용조성물 有权用于预防或治疗包含活性成分的神经病变组合物，其从VITIS VINIFERA的标准分离，其对BACE-1具有抑制作用
公开(公告)号：KR1020080025655A
公开(公告)日：2008-03-21
申请号：KR1020070095884
申请日：2007-09-20
Applicant: 한국화학연구원
IPC: A61K31/343 , A61K31/05 , A61P25/28
Abstract: A composition comprising an extract of stembark of Vitis vinifera is provided to inhibit BACE-1(beta-site APP-cleaving enzyme 1) mediating formation of beta-amyloid, known to be a causing material of various dementia such as Alzheimer's disease, thereby being usefully used for preventing and treating neurodegenerative diseases such as senile dementia. A pharmaceutical composition for preventing or treating neurodegenerative diseases comprises a compound selected from the group consisting of vitisin A, epsilon-viniferin, ampelopsin A and a mixture thereof as an effective ingredient, wherein the compound is obtained by extracting stembark of Vitis vinifera with an organic solvent selected from the group consisting of C1-4 alcohol and an aqueous solution thereof, dichloromethane, ethyl acetate and a mixture thereof.
Abstract translation: 提供了包含葡萄树葡萄树的提取物的组合物以抑制介导β-淀粉样蛋白形成的BACE-1（β-位点APP切割酶1），已知其是引起各种痴呆的物质，例如阿尔茨海默病，因此是 有用地用于预防和治疗老年性痴呆等神经变性疾病。 用于预防或治疗神经退行性疾病的药物组合物包括选自维生素A，ε-荧光素，安非他酮A及其混合物作为有效成分的化合物，其中所述化合物通过用有机物提取葡萄葡萄树 溶剂，其选自C1-4醇及其水溶液，二氯甲烷，乙酸乙酯及其混合物。
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公开(公告)号：KR1019990047157A
公开(公告)日：1999-07-05
申请号：KR1019970065413
申请日：1997-12-02
Applicant: 한국화학연구원
IPC: A01N43/76
Abstract: 본 발명은 화학식 1로 표시되는 제초성 3-아릴-테트라히드로-1,2-벤즈이속사졸린-4-온 유도체에 관한 것이다.
상기식에서 Xn은 수소, C
1 -C
4 알킬기, C
2 -C
5 알케닐기, C
2 -C
5 알키닐기, C
1 -C
4 알콕시기, C
1 -C
4 할로알킬기, C
1 -C
4 알콕시카보닐기, 아미노카보닐기, 카복시기, 메탄설포닐기, 니트로기, 히드록시기, 니트릴기, 또는 이들의 둘이상의 복합치환기를 나타낸다.-
公开(公告)号：KR1019970011302B1
公开(公告)日：1997-07-09
申请号：KR1019930015668
申请日：1993-08-13
Applicant: 한국화학연구원
IPC: C07D413/04
Abstract: Quinolinyl oxadiazole derivatives having strong herbicidal activities and excellent selectivity, especially on rice and barnyard grass, is disclosed in the present invention. Hydroxylamine chlorinate and nitrile compound are reacted in mixture solvent of water and alcohols in the presence of base to yield amidoxime. Thereafter, in the presence of base, said amidoxide is reacted with carboxylic acid chloride produced by the reaction of 3,7-dichloro-8-quinoline carboxylate and thionyl chloride to yield compound of general formula(I). In general formula(I), A and B represent hydrogen atom, sodium carbonate, etc., R represents low molecular weight alkyl, cyclo alkyl, etc.
Abstract translation: 在本发明中公开了具有强除草活性和优异选择性的喹啉基恶二唑衍生物，特别是在水稻和稗草上。 羟基胺氯化物和腈化合物在水和醇的混合溶剂中在碱的存在下反应，得到偕胺肟。 此后，在碱的存在下，所述酰胺氧化物与通过3,7-二氯-8-喹啉羧酸盐和亚硫酰氯反应生成的羧酸氯化物反应，得到通式（I）的化合物。 在通式（I）中，A和B表示氢原子，碳酸钠等，R表示低分子量烷基，环烷基等。
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公开(公告)号：KR100092184B1
公开(公告)日：1995-11-28
申请号：KR1019920011757
申请日：1992-07-02
Applicant: 한국화학연구원
IPC: C07D487/04
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公开(公告)号：KR1019950010076B1
公开(公告)日：1995-09-06
申请号：KR1019920011757
申请日：1992-07-02
Applicant: 한국화학연구원
IPC: C07D487/04
Abstract: The 5-substd phenyl-pyrazolo[3,4-d pyrimidine and 5-substd. phenyl-4-oxo-pyrazolo [3,4-d pyrimidine derivative of formula(I) is prepared. In (I), R1 is C1-4 alkyl or haloalkyl; R2 is H or C1-4 alkyl; R3 is H, C1-6 alkyl, haloalkyl, alkenyl or acyl, R4 and R5 are each halogen; A is H, alkyl, alkoxy, nitro, amino, alkyl amine, dialkyl amine or CO2R; R is H, C1-6 alkyl, substd. alkyl, haloalkyl or alkenyl [A = carboxylic acid or its ester . The cpd. (I) has a good selective herbicidal characteristic against esp. cotton plants.
Abstract translation: 5-取代苯基 - 吡唑并[3,4-d嘧啶和5-取代基。 制备式（I）的苯基-4-氧代 - 吡唑并[3,4-d嘧啶衍生物。 在（I）中，R 1为C 1-4烷基或卤代烷基; R2是H或C1-4烷基; R3是H，C1-6烷基，卤代烷基，烯基或酰基，R4和R5分别是卤素; A是H，烷基，烷氧基，硝基，氨基，烷基胺，二烷基胺或CO 2 R; R是H，C 1-6烷基，被取代。 烷基，卤代烷基或烯基[A =羧酸或其酯。 cpd。 （I）具有良好的选择性除草特性。 棉花植物。
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