公开(公告)号：DE3471655D1

公开(公告)日：1988-07-07

申请号：DE3471655

申请日：1984-01-16

Applicant: BASF AG

Inventor： ROSSY PHILLIP A DR ,  THYES MARCO DR ,  FRANKE ALBRECHT DR ,  KOENIG HORST PROF DR ,  LEHMANN HANS DIETER PROF DR ,  GRIES JOSEF DR ,  FRIEDRICH LUDWIG DR ,  LENKE DIETER PROF DR

IPC: A61K31/50 ,  A61K31/502 ,  A61K31/535 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/14 ,  C07D521/00

Abstract: Novel 6-(acylaminaryl)-3(2H)-pyridazinones of the formula (I) where R1, R2, R3, R4, A and B have the meanings given in the description, and their preparation are described. The compounds have thrombocyte aggregation-inhibiting activity.

公开(公告)号：CS50984A2

公开(公告)日：1987-07-16

申请号：CS50984

申请日：1984-01-23

Applicant: BASF AG

Inventor： ROSSY PHILIP A DR ,  THYES MARCO DR ,  FRANKE ALBRECHT DR ,  KOENIG HORST DR ,  LEHMANN HANS D DR ,  GRIES JOSEF DR ,  FRIEDRICH LUDWIG DR ,  LENKE DIETER DR

IPC: A61K31/50 ,  A61K31/502 ,  A61K31/535 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/14 ,  C07D521/00

Abstract: Novel 6-(acylaminaryl)-3(2H)-pyridazinones of the formula (I) where R1, R2, R3, R4, A and B have the meanings given in the description, and their preparation are described. The compounds have thrombocyte aggregation-inhibiting activity.

公开(公告)号：DE3371783D1

公开(公告)日：1987-07-02

申请号：DE3371783

申请日：1983-03-04

Applicant: BASF AG

Inventor： ROSSY PHILLIP A DR ,  THYES MARCO DR ,  FRANKE ALBRECHT DR ,  KOENIG HORST DR ,  GRIES JOSEF DR ,  LEHMANN HANS DIETER DR ,  LENKE DIETER DR

IPC: A61K31/50 ,  A61K31/502 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/26

Abstract: 6-Aryl-4,5-dihydro-3(2H)-pyridazinones of the formula (I) where R is hydrogen, R1 is hydrogen or C1-C3-alkyl, or R and R1 together are methylene, R2 and R3 are identical or different and are each hydrogen or C1-C6-alkyl, and A is hydroxyl, C1-C6-alkoxy, C2-C7-acyloxy, a C2-C7-carbamic acid ester group, C1-C6-alkylsulfonyloxy, C1-C6-alkylmercapto, carboxyl, C2-C7-alkoxycarbonyl or nitrile, and their preparation are described. The substances are suitable for treating disorders.

公开(公告)号：AT27453T

公开(公告)日：1987-06-15

申请号：AT83102127

申请日：1983-03-04

Applicant: BASF AG

Inventor： ROSSY PHILLIP A DR ,  THYES MARCO DR ,  FRANKE ALBRECHT DR ,  KOENIG HORST DR ,  GRIES JOSEF DR ,  LEHMANN HANS DIETER DR ,  LENKE DIETER DR

IPC: A61K31/50 ,  A61K31/502 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/26

公开(公告)号：DE3462136D1

公开(公告)日：1987-02-26

申请号：DE3462136

申请日：1984-11-26

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DR ,  SPIEGLER WOLFGANG DR ,  SIEGEL HARDO DR ,  MUELLER CLAUS D DR ,  VON PHILIPSBORN GERDA DR ,  LENKE DIETER PROF DR ,  GRIES JOSEF DR

IPC: A61K31/34 ,  A61K31/341 ,  A61K31/38 ,  A61K31/381 ,  A61K31/40 ,  A61K31/41 ,  A61K31/415 ,  A61K31/44 ,  A61K31/4402 ,  A61K31/4406 ,  A61K31/4409 ,  A61K31/4418 ,  A61K31/495 ,  A61P9/06 ,  C07D207/32 ,  C07D207/333 ,  C07D213/50 ,  C07D231/12 ,  C07D307/46 ,  C07D333/22 ,  C07D409/12

公开(公告)号：AT17571T

公开(公告)日：1986-02-15

申请号：AT84102634

申请日：1984-03-10

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DR ,  GRIES JOSEF DR ,  MUELLER CLAUS D DR ,  LENKE DIETER PROF DR

IPC: C07D211/52 ,  A61K31/13 ,  A61K31/445 ,  A61K31/451 ,  A61P9/06 ,  C07C67/00 ,  C07C213/00 ,  C07C217/32 ,  C07C313/00 ,  C07C323/25 ,  C07D211/44 ,  C07D295/08 ,  C07D295/092 ,  C07D303/22 ,  C07C93/06

公开(公告)号：DE3172852D1

公开(公告)日：1985-12-12

申请号：DE3172852

申请日：1981-12-23

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DR ,  STEINER GERD DR ,  THIEME PETER C DR ,  LENKE DIETER DR ,  GRIES JOSEF DR ,  TESCHENDORF HANS-JUERGEN DR

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/42 ,  A61K31/495 ,  A61K31/496 ,  A61K31/505 ,  A61P9/02 ,  A61P11/08 ,  A61P25/08 ,  A61P25/20 ,  C07D231/12 ,  C07D231/38 ,  C07D233/60 ,  C07D233/88 ,  C07D239/42 ,  C07D261/08 ,  C07D295/06 ,  C07D295/092 ,  C07D521/00

Abstract: Novel (hetarylphenoxy)-(phenylpiperazinyl)-propanols of the formula I where R1 is hydrogen, amino or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, and the heterocyclic structure Het. is pyrimidinyl, triazol-1-yl, imidazol-1-yl, pyrazol-3-yl or isoxazol-3-yl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly hypotensive, sedative, neuroleptic and broncholytic properties.

公开(公告)号：AT16180T

公开(公告)日：1985-11-15

申请号：AT83111353

申请日：1983-11-14

Applicant: BASF AG

Inventor： KUBINYI HUGO DR ,  TRAUT MARTIN DR ,  GRIES JOSEF DR

IPC: A61K31/455 ,  A61K31/185 ,  A61K38/00 ,  A61P9/12 ,  A61P25/04 ,  C07C67/00 ,  C07C325/00 ,  C07C327/20 ,  C07C327/32 ,  C07D205/04 ,  C07D207/16 ,  C07D209/20 ,  C07D209/26 ,  C07D211/60 ,  C07D217/26 ,  C07D277/06 ,  C07D333/24 ,  C07K5/062 ,  C07K5/065 ,  C07K5/078 ,  C07C153/07

公开(公告)号：AT12099T

公开(公告)日：1985-03-15

申请号：AT82102699

申请日：1982-03-31

Applicant: BASF AG

Inventor： EHRMANN OSKAR DR ,  RASCHACK MANFRED DR ,  GRIES JOSEF DR ,  KRETZSCHMAR ROLF DR ,  LEHMANN HANS DIETER DR ,  FRIEDRICH LUDWIG DR ,  WUPPERMANN DIRK DR ,  ZIMMERMANN FRANK DR ,  SEITZ WERNER DR ,  TREIBER HANS JOERG DR ,  DENGEL FERDINAND DR ,  FRANK WOLFRAM DR ,  KURBJUWEIT HANS-GEORG DR ,  MUELLER CLAUS D DR

IPC: A61K31/275 ,  A61K31/335 ,  C07D317/60 ,  C07D319/08 ,  C07C121/75 ,  C07C121/66 ,  C07C149/42

公开(公告)号：GR81690B

公开(公告)日：1984-12-12

申请号：GR830173392

申请日：1983-12-29

Applicant: BASF AG

Inventor： ROSSY PHILLIP A DR ,  THYES MARCO DR ,  FRANKE ALBRECHT DR ,  KOENIG HORST DR ,  LEHMANN HANS DIETER DR ,  GRIES JOSEF DR ,  FRIEDRICH LUDWIG DR ,  LENKE DIETER DR

IPC: A61K31/50 ,  A61K31/502 ,  A61K31/535 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/12 ,  C07D237/04 ,  C07D237/14 ,  C07D237/26 ,  C07D401/12 ,  C07D401/14 ,  C07D403/12 ,  C07D405/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/12 ,  C07D417/14 ,  C07D521/00

Abstract: Novel 6-(acylaminaryl)-3(2H)-pyridazinones of the formula (I) where R1, R2, R3, R4, A and B have the meanings given in the description, and their preparation are described. The compounds have thrombocyte aggregation-inhibiting activity.