FERMENTATIVE PRODUCTION OF NON-VOLATILE MICROBIAL METABOLISM PRODUCTS IN SOLID FORM

    公开(公告)号:CA2623588C

    公开(公告)日:2016-06-28

    申请号:CA2623588

    申请日:2006-09-06

    Applicant: BASF SE

    Abstract: The invention relates to a method for production of at least one non-volatile microbial metabolism product in solid form by sugar-based microbial fermentation, wherein a microbial strain producing the required metabolism product is cultivated with a sugary liquid medium with a monosaccharide content of more than 20 wt. %, based on the total weight of the liquid medium, the volatile components of the fermentation brew are mostly removed, the sugary liquid medium being produced by: a1) milling a starch source selected from cereal grains, a2) liquefying the milled material in an aqueous liquid in the presence of at least one starch-digesting enzyme and subsequent saccharification using at least one saccharifying enzyme, wherein the liquefying is carried out with addition of a partial amount of the milled material to the aqueous fluid continuously or batch-wise. The invention further relates to a solid formulation obtained by the above method of a non-volatile microbial metabolism product and the use of such a solid formulation as additive or supplement to animal or human food or for textile, leather, cellulose, paper or surface treatments.

    FERMENTATIVE PRODUCTION OF ORGANIC COMPOUNDS USING SUBSTANCES CONTAINING DEXTRIN

    公开(公告)号:CA2628748C

    公开(公告)日:2015-11-24

    申请号:CA2628748

    申请日:2006-11-27

    Applicant: BASF SE

    Abstract: The invention relates to a method for producing at least one organic compound comprising at least 3 C-atoms or at least 2 C-atoms and at least 1 N-atom by fermentation. Said method comprises the following steps: a1) a starch source is ground in order to obtain a grinding material which contains at least one part of the non-starch containing solid components of the starch source; a2) the grinding material is suspended in an aqueous liquid and said grinding material contained in the aqueous liquid is liquefied in the presence of at least one enzyme which liquefies starch, an aqueous substance which contains dextrin (1), which contains at least one part of the non-starch containing solid components of the starch source, is obtained; and b) the aqueous substance which contains dextrin (1) is used in fermentation for cultivating a micro-organism which is capable of over-producing the organic compounds; enzymes, which hydrolyse the dextrin into monosaccharides, are not added or are added in an amount of less than 0.001 wt. %, in relation to the total weight of the used starch source.

    FERMENTATIVE PRODUCTION OF ORGANIC COMPOUNDS

    公开(公告)号:CA2628954C

    公开(公告)日:2015-08-18

    申请号:CA2628954

    申请日:2006-11-27

    Applicant: BASF SE

    Abstract: The invention relates to a method for producing by fermentation at least one type of organic compound containing at least 3 C atoms or at least two C atoms and at least one N atom consisting a1) in grinding a starch source for obtaining a ground product containing at least one part of solid starch-devoid components of the starch source, 2a) in suspending the ground material in an aqueous fluid and in hydrolysing by enzimatically liquefying the starch part of the starch source and eventually metabolisable metabolisable subsequently saccharifying, thereby obtaining a first mono- and oligosaccharide-containing liquid (1), b) in adding, under fermentation conditions, the mono- and oligosaccharide-containing liquid (1) together with monosaccharides, disaccharides and/or metabolisable oligosaccharides or with a monosaccharides, disaccharides and/or metabolisable oligosaccharides-containing composition at a concentration less than 50 % by weight which is practically devoid of water insoluble solids, to a fermentation medium containing a micro organism which enables an organic compound to be overproduced.

    Preparación fermentativa de lisina

    公开(公告)号:ES2471376T3

    公开(公告)日:2014-06-26

    申请号:ES06830135

    申请日:2006-11-27

    Applicant: BASF SE

    Abstract: Procedimiento para la preparación de lisina mediante fermentación, que comprende los siguientes pasos: a1) molienda de granos de cereales como fuente de almidón con obtención de un producto molido que contiene al menos el 50 % en peso de los constituyentes sólidos que no contienen almidón contenidos en los granos de cereales molidos, ascendiendo la parte de los constituyentes sólidos que no contienen almidón en el producto molido al menos al 15 % en peso; a2) suspensión del producto molido en un líquido acuoso e hidrólisis de la parte de almidón en el producto molido mediante licuefacción enzimática y, dado el caso, sacarificación posterior, obteniéndose un primer líquido (1) que contiene mono- u oligosacáridos, que contiene los constituyentes sólidos que no contienen almidón del producto molido y en el que la concentración total de mono-, di- y oligosacáridos se encuentra en el intervalo de 100 a 400 g/kg; y b) adición del líquido (1) que contiene mono- u oligosacáridos junto con mono-, di- y/u oligosacáridos metabolizables o una composición que contiene mono-, di- y/u oligosacáridos metabolizables en una concentración de al menos el 50 % en peso y que esencialmente está exenta de sólidos insolubles en agua, a un medio de fermentación que contiene un microorganismo que está capacitado para la sobreproducción de la lisina en condiciones de fermentación, aumentándose la concentración total de mono-, di- y oligosacáridos en el primer líquido (1) mediante adición de mono-, di- y/u oligosacáridos metabolizables o mediante adición de un medio que contiene mono-, di- y/u oligosacáridos metabolizables en una concentración de al menos el 50 % en peso y que está esencialmente libre de sólidos insolubles en agua, en al menos 50 g/kg.

    58.
    发明专利
    未知

    公开(公告)号:BRPI0619022A2

    公开(公告)日:2012-12-04

    申请号:BRPI0619022

    申请日:2006-11-27

    Applicant: BASF SE

    Abstract: Method for preparing at least one organic compound (I) with at least 3 C atoms or at least two C and at least one N by fermentation. Method for preparing at least one organic compound (I) with at least 3 C atoms or at least two C and at least one N by fermentation comprises: (a1) milling a starch source (S) to form a milled product (MP) that includes at least part of the non-starch containing solid components (X) of (S); (a2) suspending (MP) in aqueous liquid and liquefying in presence of at least one liquefying enzyme to form a dextrin-containing medium (1), which includes at least part of (X); (b) using (1) in a fermentor for culturing a microorganism (MO) capable of overproducing (I). Enzymes that hydrolyze dextrins to monosaccharides are either not added or added at below 0.001wt.% on total weight of (S).

    59.
    发明专利
    未知

    公开(公告)号:BRPI0619017A2

    公开(公告)日:2012-12-04

    申请号:BRPI0619017

    申请日:2006-11-27

    Applicant: BASF SE

    Abstract: Preparation of at least one organic compound (I) with at least 3 C atoms or at least two C and at least one N by fermentation. Preparation of at least one organic compound (I) with at least 3 C atoms or at least two C and at least one N by fermentation comprises: (a) millling a starch source (S) to form a milled product (MP) that contains at least part of the non-starch-containing solid components (X) of (S); (b) suspending (MP) in an aqueous liquid and hydrolysis of the starch components by enzymatic liquefaction and optionally subsequent saccharification, to form a first liquid medium (1), containing mono- or oligo-saccharides; and (c) adding (1), together with metabolizable mono-, di- and/or oligo-saccharides (Y), or compositions containing at least 50wt.% (Y) essentially free of water-insoluble solids, to a fermentation medium that contains microorganisms (MO) which can overproduce (I), under fermentation conditions.

Patent Agency Ranking