Patent search ap:("VERTEX PHARMA") AND inv:"ROWE WILLIAM" Page 6

51.

发明专利
N-[2,4-bisz(1,1-dimetil-etil)-5-hidroxi-fenil]-1,4-dihidro-4-oxo-kinolin-3-karboxamid amorf alakjának gyógyászati kompozíciói 未知

公开(公告)号：HUE049976T2

公开(公告)日：2020-11-30

申请号：HUE17154944

申请日：2006-12-28

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , GONG YUCHUAN , YOUNG CHRISTOPHER R , CONNELLY PATRICK , ROWE WILLIAM , COSTACHE ADRIANA , KRAWIEC MARIUSZ , FENG YUSHI , TRUDEAU MARTIN

52.

发明专利
Composiciones farmacéuticas de la forma amorfa de N-[2,4-bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-dihidro-4-oxoquinolin-3-carboxamida 未知

公开(公告)号：ES2790700T3

公开(公告)日：2020-10-28

申请号：ES17154944

申请日：2006-12-28

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , GONG YUCHUAN , YOUNG CHRISTOPHER R , CONNELLY PATRICK , ROWE WILLIAM , COSTACHE ADRIANA , KRAWIEC MARIUSZ , FENG YUSHI , TRUDEAU MARTIN

IPC: C07D215/56 , A61K31/445

Abstract: Una composición farmacéutica que comprende N-[2,4-bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-dihidro-4-oxoquinolin-3-carboxamida amorfa; en la que N-[2,4-bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-dihidro-4-oxoquinolin-3-carboxamida amorfa tiene menos del 30 % de N-[2,4-bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-dihidro-4-oxoquinolin-3-carboxamida cristalina.

53.

发明专利
SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE 未知

公开(公告)号：AU2020201314A1

公开(公告)日：2020-03-12

申请号：AU2020201314

申请日：2020-02-21

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , CONNELLY PATRICK , ROWE WILLIAM , YOUNG CHRISTOPHER R , COSTACHE ADRIANA , KRAWIEC MARIUSZ , GONG YUCHUAN , FENG YUSHI , TRUDEAU MARTIN

IPC: A61K31/445

Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5 hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.

54.

发明专利
FORMULACIJA N-[2,4-BIS(1,1-DIMETILETIL)-5-HIDROKSIFENIL]-1,4-DIHIDRO-4-OKSOHINOLIN-3-KARBOKSAMIDA U OBLIKU TABLETE ZA UPOTREBU U TRETMANU CISTIČNE FIBROZE 未知

公开(公告)号：RS58604B1

公开(公告)日：2019-05-31

申请号：RSP20190432

申请日：2010-02-18

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER R , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO , ZLOKARNIK GREGOR , VAN GOOR FREDRICK F

IPC: A61K9/14 , A61K31/44 , A61K31/47 , A61K45/06 , A61P19/00 , A61P19/10 , A61P43/00

55.

发明专利
Tabletformulering af N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinolin-3-carboxamid til anvendelse til behandling af cystisk fibrose 未知

公开(公告)号：DK2464337T3

公开(公告)日：2019-04-23

申请号：DK10708442

申请日：2010-02-18

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER R , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO , ZLOKARNIK GREGOR , VAN GOOR FREDRICK F

IPC: A61K9/14 , A61K31/44 , A61K31/47 , A61K45/06 , A61P19/00 , A61P19/10 , A61P43/00

56.

发明专利
SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE 未知

公开(公告)号：AU2018204203A1

公开(公告)日：2018-07-05

申请号：AU2018204203

申请日：2018-06-13

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , CONNELLY PATRICK , ROWE WILLIAM , YOUNG CHRISTOPHER R , COSTACHE ADRIANA , KRAWIEC MARIUSZ , GONG YUCHUAN , FENG YUSHI , TRUDEAU MARTIN

IPC: A61K31/445

Abstract: The present invention relates to solid state forms of N-[2,4-bis(1 ,1 -dimethylethyl)-5 hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.

57.

发明专利
Farmacevtski sestavek N-(2,4-bis(1,1-dimetiletil)-5-hidroksifenil)-1,4-dihiro-4-oksiokinolin- 3-karboksamida in njegova administracija 未知

公开(公告)号：SI2328618T1

公开(公告)日：2018-04-30

申请号：SI200931803

申请日：2009-08-13

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO

IPC: A61K47/00 , A61K9/00 , A61K31/00

58.

发明专利
FARMACEUTISK SAMMENSÆTNING AF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLIN-3-CARBOXAMID OG ADMINISTRATION DERAF 未知

公开(公告)号：DK2328618T3

公开(公告)日：2018-02-19

申请号：DK09789125

申请日：2009-08-13

Applicant: VERTEX PHARMA

Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO

IPC: A61K47/32 , A61K9/16 , A61K9/20 , A61K9/28 , A61K31/47

59.

发明专利
N-[2,4-bisz(1,1-dimetil-etil)-5-hidroxi-fenil]-1,4-dihidro-4-oxo-kinolin-3-karboxamid szilárd formái 未知

公开(公告)号：HUE032813T2

公开(公告)日：2017-11-28

申请号：HUE06848237

申请日：2006-12-28

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , GONG YUCHUAN , YOUNG CHRISTOPHER R , CONNELLY PATRICK , ROWE WILLIAM , COSTACHE ADRIANA , KRAWIEC MARIUSZ , FENG YUSHI , TRUDEAU MARTIN

60.

发明专利
STAŁE POSTACIE N-[2,4-BIS(1,1-DIMETYLOETYLO)-5-HYDROKSYFENYLO]-1,4- DIHYDRO-4-OKSOCHINOLINO-3-KARBOKSYAMIDU 未知

公开(公告)号：PL1993360T3

公开(公告)日：2017-08-31

申请号：PL06848237

申请日：2006-12-28

Applicant: VERTEX PHARMA

Inventor： HURTER PATRICIA , GONG YUCHUAN , YOUNG CHRISTOPHER R , CONNELLY PATRICK , ROWE WILLIAM , COSTACHE ADRIANA , KRAWIEC MARIUSZ , FENG YUSHI , TRUDEAU MARTIN

IPC: C07D215/56 , A61K31/445

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