公开(公告)号：HK1081600A1

公开(公告)日：2006-05-19

申请号：HK06101676

申请日：2006-02-08

Applicant: HOFFMANN LA ROCHE

Inventor： HORN CARINA ,  HOENES JOACHIM ,  KNAPPE WOLFGANG-REIN-HOLD

IPC: C12M1/34 ,  C08F2/00 ,  C12M1/40 ,  C12Q20090101 ,  C12Q1/00 ,  C12Q1/26 ,  C12Q1/32 ,  C12Q1/54 ,  G01N21/78 ,  G01N27/327 ,  G01N33/543

Abstract: A method for producing a polymer layer on a transparent support. A photopolymerizable liquid composition is applied to the support. The photopolymerizable liquid composition is irradiated through the support such that polymerization of the liquid composition starts at the surface of the support and ends at a predetermined distance over the surface of the support. Only partial polymerization of the liquid composition takes place. A polymer layer with a predetermined thickness is formed on the support wherein the predetermined thickness is less than the thickness of the photopolymerizable liquid composition. The remaining photopolymerizable liquid composition is removed from the entire polymer layer.

公开(公告)号：DE50302548D1

公开(公告)日：2006-04-27

申请号：DE50302548

申请日：2003-07-08

Applicant: ROCHE DIAGNOSTICS GMBH ,  HOFFMANN LA ROCHE

Inventor： HORN CARINA ,  UNKRIG VOLKER ,  NORTMEYER CHRISTINE

IPC: G01N27/327 ,  C23C8/02 ,  C23C8/16 ,  C23C26/00 ,  C23C28/00 ,  C23C28/02 ,  G01N27/403 ,  G01N33/483 ,  G01N33/487

公开(公告)号：AT319081T

公开(公告)日：2006-03-15

申请号：AT03766136

申请日：2003-07-08

Applicant: HOFFMANN LA ROCHE

Inventor： HORN CARINA ,  UNKRIG VOLKER ,  NORTMEYER CHRISTINE

IPC: C23C8/02 ,  C23C26/00 ,  C23C28/00 ,  C23C28/02 ,  G01N27/403 ,  G01N27/327 ,  C23C8/16 ,  G01N33/483 ,  G01N33/487

公开(公告)号：AU2003246659A8

公开(公告)日：2004-02-23

申请号：AU2003246659

申请日：2003-07-08

Applicant: HOFFMANN LA ROCHE

Inventor： UNKRIG VOLKER ,  NORTMEYER CHRISTINE ,  HORN CARINA

IPC: C23C8/02 ,  C23C26/00 ,  C23C28/00 ,  C23C28/02 ,  G01N27/403 ,  G01N27/327 ,  C23C8/16 ,  G01N33/483 ,  G01N33/487

公开(公告)号：AU2003242747A8

公开(公告)日：2004-01-19

申请号：AU2003242747

申请日：2003-06-24

Applicant: HOFFMANN LA ROCHE

Inventor： MURAWSKI HANS-RUEDIGER ,  FREY GUENTER ,  KINTZIG HANS ,  GAA OTTO ,  HORN CARINA

IPC: G01N21/77 ,  G01N21/35 ,  G01N27/416 ,  G01N33/487 ,  G01N33/96 ,  G01N33/483

公开(公告)号：AU2003240666A1

公开(公告)日：2003-12-02

申请号：AU2003240666

申请日：2003-05-16

Applicant: HOFFMANN LA ROCHE

Inventor： HORN CARINA ,  HOENES JOACHIM ,  KNAPPE WOLFGANG-REINHOLD

IPC: C12M1/34 ,  C08F2/00 ,  C12M1/40 ,  C12Q1/00 ,  C12Q1/26 ,  C12Q1/32 ,  C12Q1/54 ,  G01N21/78 ,  G01N27/327 ,  G01N33/543

Abstract: A method for producing a polymer layer on a transparent support. A photopolymerizable liquid composition is applied to the support. The photopolymerizable liquid composition is irradiated through the support such that polymerization of the liquid composition starts at the surface of the support and ends at a predetermined distance over the surface of the support. Only partial polymerization of the liquid composition takes place. A polymer layer with a predetermined thickness is formed on the support wherein the predetermined thickness is less than the thickness of the photopolymerizable liquid composition. The remaining photopolymerizable liquid composition is removed from the entire polymer layer.

公开(公告)号：AU2003232790A1

公开(公告)日：2003-12-02

申请号：AU2003232790

申请日：2003-05-16

Applicant: HOFFMANN LA ROCHE

Inventor： HORN CARINA ,  HOENES JOACHIM ,  KNAPPE WOLFGANG-REINHOLD

IPC: C12M1/34 ,  C08F2/00 ,  C12M1/40 ,  C12Q1/00 ,  C12Q1/26 ,  C12Q1/32 ,  C12Q1/54 ,  G01N21/78 ,  G01N27/327 ,  G01N33/543

Abstract: A method for producing a polymer layer on a transparent support. A photopolymerizable liquid composition is applied to the support. The photopolymerizable liquid composition is irradiated through the support such that polymerization of the liquid composition starts at the surface of the support and ends at a predetermined distance over the surface of the support. Only partial polymerization of the liquid composition takes place. A polymer layer with a predetermined thickness is formed on the support wherein the predetermined thickness is less than the thickness of the photopolymerizable liquid composition. The remaining photopolymerizable liquid composition is removed from the entire polymer layer.

公开(公告)号：CA2910360C

公开(公告)日：2018-07-10

申请号：CA2910360

申请日：2014-02-24

Applicant: HOFFMANN LA ROCHE

Inventor： BAUER-ESPINDOLA KLAUS ANDREAS ,  HORN CARINA ,  MARQUANT MICHAEL ,  NORTMEYER CHRISTINE ,  UNKRIG VOLKER

IPC: G01N21/84 ,  G01N21/64 ,  G01N27/02 ,  G01N27/327

Abstract: A method for detecting at least one analyte in a body fluid (112) is disclosed. The method comprises the following steps: a) performing an optical measurement, wherein at least one test chemical (120) is contacted with the body fluid (112), wherein the test chemical (120) is an optical test chemical (120) and is adapted to perform at least one detection reaction in the presence of the analyte, wherein at least one optically detectable property of at least one of the body fluid (112) and the test chemical (120) is changed due to the detection reaction, wherein at least one optical measurement value is generated; b) performing at least one impedance measurement, wherein at least two impedance measurement electrodes (130) are used, wherein at least one alternating electrical signal is applied to the body fluid (112) via the impedance measurement electrodes (130) and wherein at least one answer signal is recorded, wherein at least one impedance measurement value is generated; c) performing at least one evaluation step, wherein, in the evaluation step, at least one evaluation algorithm is used, wherein the optical measurement value and the impedance measurement value are used for determining a concentration of the analyte in the body fluid (112).

公开(公告)号：PL2936124T3

公开(公告)日：2017-08-31

申请号：PL13811932

申请日：2013-12-19

Applicant: HOFFMANN LA ROCHE

Inventor： AIGNER SIMON ,  CHEMNITIUS GABRIELE ,  HORN CARINA ,  LIMBURG BERND ,  OTTENSTEIN TIMO ,  PETRICH WOLFGANG ,  PLUM MARKUS ,  RINGEMANN CHRISTIAN ,  SERR MARKUS

IPC: G01N21/77 ,  G01N21/27 ,  G01N21/84

公开(公告)号：CA2750474C

公开(公告)日：2017-07-25

申请号：CA2750474

申请日：2010-02-12

Applicant: HOFFMANN LA ROCHE

Inventor： HORN CARINA ,  GASSLER-DIETSCHE CLAUDIA ,  HEINDL DIETER ,  HONES JOACHIM ,  MEIER THOMAS ,  SCHMUCK RAINER

IPC: C12Q1/32

Abstract: The present description concerns a method for determining an analyte as well as a diagnostic element suitable therefor, the method comprising the steps of contacting a sample containing the analyte with a diagnostic element comprising a dry reagent layer which contains a mutated glucose dehydrogenase (EC 1.1.1.47) which is specific for the analyte, and an artificial coenzyme; and determining at least one of the presence and the amount of the analyte.