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公开(公告)号:DE69613347T2
公开(公告)日:2002-04-18
申请号:DE69613347
申请日:1996-01-11
Applicant: ABBOTT LAB
Inventor: MEYER D , ALTENBACH J , BASHA Z , CARROLL A , DRIZIN IRENE , KERWIN F , LEBOLD A , LEE L , PRATT K , SIPPY B , TIETJE R , YAMAMOTO M
IPC: A61K31/505 , A61K31/519 , A61P13/02 , A61P15/00 , A61P25/02 , C07D401/06 , C07D403/06 , C07D471/04 , C07D473/04 , C07D475/02 , C07D487/04 , C07D491/04 , C07D491/056 , C07D495/04 , C07D498/04 , C07D487/02 , C07D495/02 , C07D487/00
Abstract: The present invention relates to a compound of the formula and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are alpha -1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are alpha -1 antagonist compositions and a method for antagonizing alpha -1 receptors and treating BPH.
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公开(公告)号:DE69613347D1
公开(公告)日:2001-07-19
申请号:DE69613347
申请日:1996-01-11
Applicant: ABBOTT LAB
Inventor: MEYER D , ALTENBACH J , BASHA Z , CARROLL A , DRIZIN IRENE , KERWIN F , LEBOLD A , LEE L , PRATT K , SIPPY B , TIETJE R , YAMAMOTO M
IPC: A61K31/505 , A61K31/519 , A61P13/02 , A61P15/00 , A61P25/02 , C07D401/06 , C07D403/06 , C07D471/04 , C07D473/04 , C07D475/02 , C07D487/04 , C07D491/04 , C07D491/056 , C07D495/04 , C07D498/04 , C07D487/02 , C07D495/02 , C07D487/00
Abstract: The present invention relates to a compound of the formula and the pharmaceutically acceptable salts thereof wherein W is a bicyclic heterocyclic ring system. The compounds are alpha -1 adrenergic antagonists and are useful in the treatment of BPH; also disclosed are alpha -1 antagonist compositions and a method for antagonizing alpha -1 receptors and treating BPH.
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公开(公告)号:DE69609051T2
公开(公告)日:2001-03-22
申请号:DE69609051
申请日:1996-01-11
Applicant: ABBOTT LAB
Inventor: MEYER D , ALTENBACH J , BASHA Z , CARROLL A , DRIZIN IRENE , KERWIN F , LEBOLD A , LEE L , ELMORE W , SIPPY B , TIETJE R , WENDT D , YAMAMOTO M
IPC: A61K31/437 , A61K31/519 , A61P13/00 , A61P13/08 , A61P43/00 , C07D403/06 , C07D471/04 , C07D471/14 , C07D487/04 , C07D487/14 , C07D491/04 , C07D491/048 , C07D491/14 , C07D491/147 , C07D495/04 , C07D495/14 , C07D487/16 , A61K31/395
Abstract: The present invention relates to a compound of the formula and the pharmaceutically acceptable salts thereof wherein W is a tricyclic heterocyclic ring system; which is an alpha -1 adrenergic antagonist and is useful in the treatment of BPH; also disclosed are alpha -1 antagonist compositions and a method for antagonizing alpha -1 receptors and treating BPH.
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公开(公告)号:DE69822668T2
公开(公告)日:2005-03-10
申请号:DE69822668
申请日:1998-12-18
Applicant: ABBOTT LAB
Inventor: HOLLADAY W , ABREO A , GUNN E , LIN NAN-HORNG , GARVEY S , RYTHER KEITH , LEBOLD A , ELLIOTT L , HE YUN , WASIAK T , BAI HAO , DART J , EHRLICH P , LI YIHONG , KINCAID F , SCHKERYANTZ M , LYNCH K
IPC: A61K31/427 , A61K31/4427 , A61K31/4439 , A61K31/4545 , A61K31/4709 , A61K31/4725 , A61K31/497 , A61K31/501 , A61K31/506 , A61P25/00 , A61P25/22 , A61P25/28 , A61P25/30 , A61P43/00 , C07D401/12 , C07D403/12 , C07D417/12 , C07D455/02 , C07D487/04 , A61K31/40 , A61K31/425 , A61K31/44 , A61K31/47 , A61K31/50 , A61K31/505
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公开(公告)号:DE69822668D1
公开(公告)日:2004-04-29
申请号:DE69822668
申请日:1998-12-18
Applicant: ABBOTT LAB
Inventor: HOLLADAY W , ABREO A , GUNN E , LIN NAN-HORNG , GARVEY S , RYTHER KEITH , LEBOLD A , ELLIOTT L , HE YUN , WASIAK T , BAI HAO , DART J , EHRLICH P , LI YIHONG , KINCAID F , SCHKERYANTZ M , LYNCH K
IPC: A61K31/427 , A61K31/4427 , A61K31/4439 , A61K31/4545 , A61K31/4709 , A61K31/4725 , A61K31/497 , A61K31/501 , A61K31/506 , A61P25/00 , A61P25/22 , A61P25/28 , A61P25/30 , A61P43/00 , C07D401/12 , C07D403/12 , C07D417/12 , C07D455/02 , C07D487/04 , A61K31/40 , A61K31/425 , A61K31/44 , A61K31/47 , A61K31/50 , A61K31/505
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公开(公告)号:DE69609051D1
公开(公告)日:2000-08-03
申请号:DE69609051
申请日:1996-01-11
Applicant: ABBOTT LAB
Inventor: MEYER D , ALTENBACH J , BASHA Z , CARROLL A , DRIZIN IRENE , KERWIN F , LEBOLD A , LEE L , ELMORE W , SIPPY B , TIETJE R , WENDT D , YAMAMOTO M
IPC: A61K31/437 , A61K31/519 , A61P13/00 , A61P13/08 , A61P43/00 , C07D403/06 , C07D471/04 , C07D471/14 , C07D487/04 , C07D487/14 , C07D491/04 , C07D491/048 , C07D491/14 , C07D491/147 , C07D495/04 , C07D495/14 , C07D487/16 , A61K31/395
Abstract: The present invention relates to a compound of the formula and the pharmaceutically acceptable salts thereof wherein W is a tricyclic heterocyclic ring system; which is an alpha -1 adrenergic antagonist and is useful in the treatment of BPH; also disclosed are alpha -1 antagonist compositions and a method for antagonizing alpha -1 receptors and treating BPH.
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