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公开(公告)号：WO2005110410A3
公开(公告)日：2007-03-29
申请号：PCT/US2005016903
申请日：2005-05-13
Applicant: ABBOTT LAB , CUSACK KEVIN , SALMERON-GARCIA JOSE-ANDRES , GORDON THOMAS D , BARBERIS CLAUDE E , ALLEN HAMISH J , BISCHOFF AGNIESZKA K , ERICSSON ANNA M , FRIEDMAN MICHAEL M , GEORGE DAWN M , ROTH GREGORY P , TALANIAN ROBERT V , THOMAS CHRISTINE , WALLACE GRIER A , WISHART NEIL , YU ZHENGTIAN
Inventor： CUSACK KEVIN , SALMERON-GARCIA JOSE-ANDRES , GORDON THOMAS D , BARBERIS CLAUDE E , ALLEN HAMISH J , BISCHOFF AGNIESZKA K , ERICSSON ANNA M , FRIEDMAN MICHAEL M , GEORGE DAWN M , ROTH GREGORY P , TALANIAN ROBERT V , THOMAS CHRISTINE , WALLACE GRIER A , WISHART NEIL , YU ZHENGTIAN
IPC: C07D471/02 , A61K31/4743 , C07D471/04 , C07D491/04 , C07D495/04 , C07D498/02
CPC classification number: C07D471/04 , A61K31/4743 , C07D487/04 , C07D491/04 , C07D495/04
Abstract: A compound or pharmaceutically acceptable salts thereof of Formula (I) wherein the substituents are as defined herein, which are useful as kinase inhibitors.
Abstract translation: 式（I）的化合物或其药学上可接受的盐，其中取代基如本文所定义，其可用作激酶抑制剂。
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公开(公告)号：WO2011163478A3
公开(公告)日：2012-05-03
申请号：PCT/US2011041633
申请日：2011-06-23
Applicant: ABBOTT LAB , GHAYUR TARIQ , LIU JUNJIAN , JAKWAY JAMES J , TALANIAN ROBERT V , BENATUIL LORENZO
Inventor： GHAYUR TARIQ , LIU JUNJIAN , JAKWAY JAMES J , TALANIAN ROBERT V , BENATUIL LORENZO
IPC: A61K39/395 , C07K16/00 , C12P21/02
CPC classification number: C07K16/2875 , C07K16/241 , C07K16/468 , C07K2317/31 , C07K2317/64
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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公开(公告)号：WO2011163478A4
公开(公告)日：2012-07-05
申请号：PCT/US2011041633
申请日：2011-06-23
Applicant: ABBOTT LAB , GHAYUR TARIQ , LIU JUNJIAN , JAKWAY JAMES J , TALANIAN ROBERT V , BENATUIL LORENZO
Inventor： GHAYUR TARIQ , LIU JUNJIAN , JAKWAY JAMES J , TALANIAN ROBERT V , BENATUIL LORENZO
IPC: A61K39/395 , C07K16/00 , C12P21/02
CPC classification number: C07K16/2875 , C07K16/241 , C07K16/468 , C07K2317/31 , C07K2317/64
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白，制备方法，具体涉及用于预防，诊断和/或治疗疾病的用途。
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公开(公告)号：WO2007117465A3
公开(公告)日：2008-08-28
申请号：PCT/US2007008307
申请日：2007-04-02
Applicant: ABBOTT LAB , ERICSSON ANNA M , BURCHAT ANDREW , FRANK KRISTINE E , CALDERWOOD DAVID J , ABBOTT LILY K , ARGIRIADI MARIA A , BORHANI DAVID W , CUSACK KEVIN P , DIXON RICHARD W , GORDON THOMAS D , MULLEN KELLY D , TALANIAN ROBERT V , WU XIAOYUN , ZHANG XIAOLEI , WANG LU X , LI BIQIN , BARBERIS CLAUDE E , WISHART NEIL
Inventor： ERICSSON ANNA M , BURCHAT ANDREW , FRANK KRISTINE E , CALDERWOOD DAVID J , ABBOTT LILY K , ARGIRIADI MARIA A , BORHANI DAVID W , CUSACK KEVIN P , DIXON RICHARD W , GORDON THOMAS D , MULLEN KELLY D , TALANIAN ROBERT V , WU XIAOYUN , ZHANG XIAOLEI , WANG LU X , LI BIQIN , BARBERIS CLAUDE E , WISHART NEIL
IPC: A61K31/5377
CPC classification number: C07D487/04 , C07D403/12 , C07D403/14 , C07D409/04 , C07D409/14
Abstract: Novel compounds of Formula (I) or pharmaceutically acceptable salts, prodrugs and biologically active metabolites thereof of Formula (I) wherein the substituents are as defined herein, which are useful as therapeutic agents.
Abstract translation: 式（I）的新型化合物或其药学上可接受的盐，前体药物和式（I）的生物活性代谢物，其中取代基如本文所定义，其可用作治疗剂。
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公开(公告)号：EP2279261A4
公开(公告)日：2011-12-28
申请号：EP09732819
申请日：2009-04-16
Applicant: ABBOTT LAB
Inventor： TALANIAN ROBERT V
CPC classification number: C12Q1/37
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Patent Agency Ranking
公开(公告)号：EP1753428A4
公开(公告)日：2010-09-15
申请号：EP05778736
申请日：2005-05-13
Applicant: ABBOTT LAB
Inventor： CUSACK KEVIN , SALMERON-GARCIA JOSE-ANDRES , GORDON THOMAS D , BARBERIS CLAUDE E , ALLEN HAMISH J , BISCHOFF AGNIESZKA K , ERICSSON ANNA M , FRIEDMAN MICHAEL M , GEORGE DAWN M , ROTH GREGORY P , TALANIAN ROBERT V , THOMAS CHRISTINE , WALLACE GRIER A , WISHART NEIL , YU ZHENGTIAN
IPC: C07D471/02 , A61K31/4743 , C07D471/04 , C07D491/04 , C07D495/04 , C07D498/02
CPC classification number: C07D471/04 , A61K31/4743 , C07D487/04 , C07D491/04 , C07D495/04
Abstract: A compound or pharmaceutically acceptable salts thereof of Formula (I) wherein the substituents are as defined herein, which are useful as kinase inhibitors.
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公开(公告)号：EP2001480A4
公开(公告)日：2011-06-15
申请号：EP07754773
申请日：2007-04-02
Applicant: ABBOTT LAB
Inventor： ERICSSON ANNA M , BURCHAT ANDREW , FRANK KRISTINE E , CALDERWOOD DAVID J , ABBOTT LILY K , ARGIRIADI MARIA A , BORHANI DAVID W , CUSACK KEVIN P , DIXON RICHARD W , GORDON THOMAS D , MULLEN KELLY D , TALANIAN ROBERT V , WU XIAOYUN , ZHANG XIAOLEI , WANG LU X , LI BIQIN , BARBERIS CLAUDE E , WISHART NEIL
IPC: A61K31/196 , A61P35/00 , C07D403/12
CPC classification number: C07D487/04 , C07D403/12 , C07D403/14 , C07D409/04 , C07D409/14
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公开(公告)号：CA2644910C
公开(公告)日：2014-01-28
申请号：CA2644910
申请日：2007-04-02
Applicant: ABBOTT LAB
Inventor： ERICSSON ANNA M , BURCHAT ANDREW , FRANK KRISTINE E , CALDERWOOD DAVID J , ABBOTT LILY K , ARGIRIADI MARIA A , BORHANI DAVID W , CUSACK KEVIN P , DIXON RICHARD W , GORDON THOMAS D , MULLEN KELLY D , TALANIAN ROBERT V , WU XIAOYUN , ZHANG XIAOLEI , WANG LU X , LI BIQIN , BARBERIS CLAUDE E , WISHART NEIL
IPC: A61K31/5377
Abstract: Novel compounds of Formula (I) or pharmaceutically acceptable salts, prodrugs and biologically active metabolites thereof of Formula (I) wherein the substituents are as defined herein, which are useful as therapeutic agents.
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公开(公告)号：SG188944A1
公开(公告)日：2013-05-31
申请号：SG2012094900
申请日：2011-06-23
Applicant: ABBOTT LAB
Inventor： GHAYUR TARIQ , LIU JUNJIAN , JAKWAY JAMES J , TALANIAN ROBERT V , BENATUIL LORENZO
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
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公开(公告)号：MX2008012482A
公开(公告)日：2008-10-10
申请号：MX2008012482
申请日：2007-04-02
Applicant: ABBOTT LAB
Inventor： CALDERWOOD DAVID J , WISHART NEIL , DIXON RICHARD W , ERICSSON ANNA M , LI BIQIN , GORDON THOMAS D , BARBERIS CLAUDE E , TALANIAN ROBERT V , FRANK KRISTINE E , BURCHAT ANDREW , ABBOTT LILY K , ARGIRIADI MARIA A , BORHANI DAVID W , CUSACK KEVIN P , MULLEN KELLY D , WU XIAOYUN , ZHANG XIAOLEI , WANG LU X
IPC: A61K31/5377
Abstract: Se describen nuevos compuestos de fórmula (I) o sales farmacéuticamente aceptables, profármacos y metabilitos biológicamente activos de los mismos de fórmula (I), en donde los sustituyentes son según lo definido en la presente, los cuales son útiles como agentes terapéuticos.
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