METHODS AND COMPOSITION FOR SEQUENCING MODIFIED NUCLEIC ACIDS

    公开(公告)号:CA2867489A1

    公开(公告)日:2013-10-03

    申请号:CA2867489

    申请日:2013-03-18

    Abstract: Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, a basic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.

Patent Agency Ranking