FLUORESCENCE MICROSCOPE LIGHT SOURCE APPARATUS AND FLUORESCENCE MICROSCOPE

    公开(公告)号:US20180067295A1

    公开(公告)日:2018-03-08

    申请号:US15695464

    申请日:2017-09-05

    Abstract: Disclosed are a fluorescence microscope light source apparatus and a fluorescence microscope capable of obtaining high-luminance light in a wavelength of 500 to 550 nm and having reduced background noise when a sample is observed. The fluorescence microscope light source apparatus to be installed in a fluorescence microscope including an illumination light bandpass filter includes: a laser diode that emits blue light as excitation light; a phosphor that converts the excitation light from the laser diode into illumination fluorescence with a wavelength region of 500 to 550 nm; an optical system that extracts the illumination fluorescence from the phosphor; a first condenser lens that condenses the excitation light onto the phosphor; a light guide body having one end face on which the illumination fluorescence is incident and the other end face from which the illumination fluorescence exits; and a second condenser lens that condenses the illumination fluorescence onto the one end face of the light guide body. A band-elimination filter that blocks or attenuates light, out of the illumination fluorescence, in a wavelength region including a transmission maximum wavelength and including no transmission minimum wavelength in the illumination light bandpass filter is provided on a light path of the illumination fluorescence.

    SPECTRAL COLORIMETRIC APPARATUS AND IMAGE FORMING APPARATUS USING THE SAME
    175.
    发明申请
    SPECTRAL COLORIMETRIC APPARATUS AND IMAGE FORMING APPARATUS USING THE SAME 有权
    使用相同的彩色彩色装置和图像形成装置

    公开(公告)号:US20130250295A1

    公开(公告)日:2013-09-26

    申请号:US13888504

    申请日:2013-05-07

    Abstract: A spectral colorimetric apparatus for detecting a color of an image of a subject, including: an illumination optical system illuminating the subject on a detection surface; a spectral optical system including a spectral element spectrally separating the beam diffused by the subject and a light receiving element array detecting a spectral intensity distribution; and a guiding optical system for guiding a beam diffused by the subject, wherein: the detection surface is parallel to a spectral plane including a principal ray of a beam entering the spectral optical system and a principal ray of a beam spectrally separated; the principal ray of the beam enters the spectral optical system within the spectral plane obliquely to a line joining a center of the light receiving element array with a surface vertex of the spectral element; and a light receiving surface of the light receiving element array is orthogonal to the spectral plane.

    Abstract translation: 一种用于检测被摄体的图像的颜色的光谱比色装置,包括:照射光学系统,在检测面上照射被摄体; 光谱光学系统,包括频谱分离由对象漫射的光束的光谱元件和检测光谱强度分布的光接收元件阵列; 以及引导光学系统,用于引导被对象漫射的光束,其中:所述检测表面平行于包括进入所述光谱系统的光束的主光线和光谱分离的光束的主光束的光谱平面; 光束的主射线进入光谱平面内的光谱系统,倾斜于连接光接收元件阵列的中心与光谱元件的表面顶点的线; 并且光接收元件阵列的光接收表面与光谱平面正交。

    Fiber optic probe scatterometers for spectroscopy measurements
    176.
    发明授权
    Fiber optic probe scatterometers for spectroscopy measurements 有权
    用于光谱测量的光纤探头散射仪

    公开(公告)号:US08525990B2

    公开(公告)日:2013-09-03

    申请号:US13416771

    申请日:2012-03-09

    Abstract: Fiber optic probe scatterometers for spectroscopy measurements are disclosed. An example device includes an optically transparent illumination tube, an opaque tube, an inner surface of the opaque tube being adjacent an outer surface of the illumination tube and the illumination tube being disposed within the opaque tube, and an optical fiber disposed within and spaced a first distance from the illumination tube, wherein the opaque tube is to be coupled to a spectrometer and an illumination source to provide a light signal along the illumination tube and to collect a scattered light signal via the optical fiber for the spectrometer.

    Abstract translation: 公开了用于光谱测量的光纤探针散射仪。 示例性装置包括光学透明的照明管,不透明管,不透明管的内表面邻近照明管的外表面,并且照明管设置在不透明管内,以及光纤, 与照明管的第一距离,其中不透明管将耦合到光谱仪和照明源,以沿着照明管提供光信号,并且经由用于光谱仪的光纤收集散射光信号。

    Device for measuring fluorescent radiation on biological substances with a semi-conductor sensor arrangement
    177.
    发明授权
    Device for measuring fluorescent radiation on biological substances with a semi-conductor sensor arrangement 失效
    用半导体传感器布置测量生物物质荧光辐射的装置

    公开(公告)号:US08471221B2

    公开(公告)日:2013-06-25

    申请号:US12680964

    申请日:2008-10-01

    Applicant: Thomas Hennig

    Inventor: Thomas Hennig

    Abstract: The invention relates to a device for measuring fluorescent radiation emitted by biological substances, comprising a light source, a capturing unit, an evaluation unit, at least one emission fiber, and at least one detection fiber. Said emission fiber guides excitation radiation to the biological substrate and the detection fiber receives fluorescent radiation and guides it to the evaluation unit. The capturing unit comprises a semiconductor sensor arrangement that detects fluorescent radiation emitted by the biological substance in wave length areas that are separate from each other, are arranged. Data sets of at least two different reference measurements on at least two different biological substances are stored and compared to the measured measurement values to the stored data sets and issues a result relating to the pathological attacks of the examined biological substances and/or relating to the type of examined, biological substances.

    Abstract translation: 本发明涉及一种用于测量由生物物质发射的荧光辐射的装置,包括光源,捕获单元,评估单元,至少一种发射光纤和至少一种检测光纤。 所述发射光纤将激发辐射引导到生物衬底,并且检测光纤接收荧光辐射并将其引导到评估单元。 捕获单元包括在彼此分离的波长区域中检测由生物物质发射的荧光辐射的半导体传感器装置。 存储至少两种不同生物物质的至少两种不同参考测量值的数据集,并将其与所测量的测量值进行比较以存储数据集,并发布与所检查的生物物质的病理攻击相关的结果和/或与 检查类型,生物物质。

    Apparatus for transforming the aspect ratio of an optical input field based on stacked waveguides
    178.
    发明授权
    Apparatus for transforming the aspect ratio of an optical input field based on stacked waveguides 有权
    用于基于堆叠波导变换光输入场的纵横比的装置

    公开(公告)号:US08442363B2

    公开(公告)日:2013-05-14

    申请号:US12786751

    申请日:2010-05-25

    Abstract: An apparatus consisting of stacked slab waveguides whose outputs are vertically staggered is disclosed. At the input to the stacked waveguides, the entrances to each slab lie in approximately the same vertical plane. A spot which is imaged onto the input will be transformed approximately to a set of staggered rectangles at the output, without substantial loss in brightness, which staggered rectangles can serve as a convenient input to a spectroscopic apparatus. A slit mask can be added to spatially filter the outputs so as to present the desired transverse width in the plane of the spectroscopic apparatus parallel to its dispersion.

    Abstract translation: 公开了一种由输出垂直交错的堆叠平板波导组成的装置。 在堆叠波导的输入端,每个板的入口处于大致相同的垂直平面。 成像在输入上的点将在输出处大致变换成一组交错的矩形,而不会明显地损失亮度,这种交错矩形可以作为分光装置的方便的输入。 可以添加狭缝掩模以对输出进行空间过滤,以在分光装置的平面中呈现与其分散体平行的期望的横向宽度。

    Optical Spectrometer with Underfilled Fiber Optic Sample Interface
    180.
    发明申请
    Optical Spectrometer with Underfilled Fiber Optic Sample Interface 有权
    具有未充足光纤样品接口的光谱仪

    公开(公告)号:US20130016348A1

    公开(公告)日:2013-01-17

    申请号:US13183346

    申请日:2011-07-14

    Abstract: An optical device is provided that includes a converging lens device, a transmitting optical fiber, a sample holder, and a receiving optical fiber. The converging lens device focuses light onto the transmitting optical fiber, which receives the focused light through an entrance face and transmits the light from an exit face, through a sample, and onto the receiving optical fiber. The sample holder holds the sample for analysis. The receiving optical fiber receives the light through an entrance face of the receiving optical fiber after transmission through the sample. The converging lens device is positioned to focus the light onto the entrance face of the transmitting optical fiber such that a half-angle of the angular distribution of the focused light that reaches the entrance face of the transmitting optical fiber is selected to underfill an entrance aperture of the entrance face of the receiving optical fiber in both a spatial dimension and an angular dimension.

    Abstract translation: 提供一种光学装置,其包括会聚透镜装置,发射光纤,样本保持器和接收光纤。 会聚透镜装置将光聚焦到发射光纤上,发射光纤通过入射面接收聚焦光,并将光从出射面透过样品,并传输到接收光纤上。 样品架持有样品进行分析。 接收光纤在通过样品传输后通过接收光纤的入射面接收光。 会聚透镜装置被定位成将光聚焦到发射光纤的入射面上,使得到达发射光纤的入射面的聚焦光的角分布的半角被选择为向下填充入射孔 在空间尺寸和角度尺寸上的接收光纤的入射面。

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