公开(公告)号：US20120140227A1

公开(公告)日：2012-06-07

申请号：US13375396

申请日：2010-06-17

Applicant: Thomas Willuweit ,  Achim Sack ,  Ralf Griesbach

Inventor： Thomas Willuweit ,  Achim Sack ,  Ralf Griesbach

IPC: G01J3/42

CPC classification number: G01N21/255 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0237 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0291 ,  G01J3/10 ,  G01N21/78 ,  G01N21/8507 ,  G01N2021/3181 ,  G01N2201/0221 ,  G01N2201/0627

Abstract: The present invention creates a spectrometer (1; 1′) for measuring the concentration of at least one analyte in a fluid sample (2; 2′), with a light source (3; 3′) to generate a light beam (4; 4′), with a photosensor (5; 5′) to receive the light beam (4; 4′), and with a measurement length (6; 6′), in which the fluid sample (2; 2′) can be placed, in the beam path of the light beam (4; 4′), the measurement length (6; 6′) being provided in changeable form.

Abstract translation: 本发明产生用于测量流体样品（2; 2'）中的至少一种分析物的浓度的光谱仪（1; 1'），用光源（3; 3'）产生光束（4; 4'），具有用于接收光束（4; 4'）的光电传感器（5; 5'），并具有测量长度（6; 6'），其中流体样品（2; 2'）可以 放置在光束（4; 4'）的光束路径中，测量长度（6; 6'）以可变形式提供。

公开(公告)号：US08189975B2

公开(公告)日：2012-05-29

申请号：US12573278

申请日：2009-10-05

Applicant: Ryan Edward Sullivan ,  Qingxiong Li ,  Xin Jack Zhou ,  Sean Xiaolu Wang

Inventor： Ryan Edward Sullivan ,  Qingxiong Li ,  Xin Jack Zhou ,  Sean Xiaolu Wang

IPC: G02B6/06

CPC classification number: G01N21/65 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0291 ,  G01J3/44 ,  G01N21/6458 ,  G01N2021/6417 ,  G01N2021/6484 ,  G02B21/16 ,  Y10T436/112499

Abstract: A fiber spectroscopic probe that can be mounted directly above the objective lens of a standard microscope to add a spectroscopic function to the microscope. The fiber spectroscopic probe only consists of a minimum number of optical components and is compact enough to induce minimum alteration to the optical path of the microscope.

Abstract translation: 一种可以直接安装在标准显微镜物镜正上方的光纤光谱探头，为显微镜增加光谱功能。 光纤光谱探头仅由最少数量的光学元件组成，并且足够紧凑，可以对显微镜的光路产生最小的改变。

公开(公告)号：US08189199B2

公开(公告)日：2012-05-29

申请号：US12572143

申请日：2009-10-01

Applicant: Charles W. Robertson, Jr. ,  Catherine T. Williams ,  Jonathan Pundt

Inventor： Charles W. Robertson, Jr. ,  Catherine T. Williams ,  Jonathan Pundt

IPC: G01N21/00 ,  G01N1/10

CPC classification number: G01N21/03 ,  B01L9/00 ,  B01L2300/0654 ,  B01L2300/089 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0267 ,  G01N21/01 ,  G01N21/0303 ,  G01N21/253 ,  G01N33/1806 ,  G01N2021/0346 ,  G01N2021/035 ,  G01N2021/036 ,  G01N2021/0367 ,  G01N2021/6484

Abstract: A dual-mode method and apparatus of selectively measuring samples in either a vessel or as a surface tension retained sample held between two opposing pedestals is introduced. In either configuration, such modes further contain optical paths from a source system through a small-volume or large-volume sample to a spectrometer based system. Such a system enables a user to measure samples with absorbances ranging from about 0.005 up to about 2.0 Absorbance Units for any given wavelength.

Abstract translation: 引入了选择性地测量容器中的样品或保持在两个相对的基座之间的表面张力保持样品的双模式方法和装置。 在任一配置中，这种模式还包含从源系统通过小容量或大容量样本到基于光谱仪的系统的光路。 这样的系统使得用户能够测量任何给定波长的吸光度范围为约0.005至约2.0吸光度单位的样品。

公开(公告)号：US20120119117A1

公开(公告)日：2012-05-17

申请号：US13295800

申请日：2011-11-14

Applicant: John T. Fourkas ,  Linjie Li ,  Sanghee Nah

Inventor： John T. Fourkas ,  Linjie Li ,  Sanghee Nah

IPC: G01J3/10 ,  B32B15/02 ,  B05D3/06 ,  D02G3/22 ,  B82Y20/00

CPC classification number: G01J3/10 ,  B82Y20/00 ,  G01J3/0218 ,  G01N21/648 ,  G02B6/107 ,  G02B6/1226 ,  Y10T428/2913 ,  Y10T428/31678

Abstract: A method of fabricating a nanodevice includes providing a nanowire having a first portion and a second portion. The nanowire has a polymer coating. A nanostructure is provided that is proximate to the second portion of the nanowire. Solely the first portion of the nanowire is irradiated with near-infrared radiation, thereby exciting the first portion to generate ultraviolet radiation. The generated ultraviolet radiation is guided from the first portion along the nanowire toward the second portion, so that a region of the polymer coating on the second portion is polymerized and bonds the nanostructure to the nanowire.

Abstract translation: 制造纳米器件的方法包括提供具有第一部分和第二部分的纳米线。 纳米线具有聚合物涂层。 提供了接近纳米线的第二部分的纳米结构。 单纯地，用近红外辐射照射纳米线的第一部分，从而激发第一部分以产生紫外线辐射。 产生的紫外线辐射从第一部分沿着纳米线向第二部分引导，使得第二部分上的聚合物涂层的区域聚合并将纳米结构结合到纳米线上。

公开(公告)号：US20120092678A1

公开(公告)日：2012-04-19

申请号：US13333351

申请日：2011-12-21

Applicant: Noam Babayoff

Inventor： Noam Babayoff

IPC: G01B11/24

CPC classification number: H04N13/15 ,  A61B1/00009 ,  A61B1/00096 ,  A61B1/0615 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/0676 ,  A61B1/0684 ,  A61B1/24 ,  A61B1/247 ,  A61B5/0068 ,  A61B5/0088 ,  A61B5/1077 ,  A61B5/1079 ,  A61C9/0053 ,  A61C9/0066 ,  A61C19/04 ,  G01B11/24 ,  G01B11/25 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/0224 ,  G01J3/0243 ,  G01J3/0256 ,  G01J3/10 ,  G01J3/462 ,  G01J3/50 ,  G01J3/501 ,  G01J3/508 ,  G01J3/51 ,  G01N21/255 ,  G06F19/00 ,  G06T7/0012 ,  G06T7/12 ,  G06T7/90 ,  G06T2207/10024 ,  G06T2207/10028 ,  G06T2207/30036 ,  H01L27/14868 ,  H04N13/207 ,  H04N13/257 ,  H04N13/271 ,  H04N13/296

Abstract: Provided is a device for determining the surface topology and associated color of a structure, such as a teeth segment, including a scanner for providing depth data for points along a two-dimensional array substantially orthogonal to the depth direction, and an image acquisition means for providing color data for each of the points of the array, while the spatial disposition of the device with respect to the structure is maintained substantially unchanged. A processor combines the color data and depth data for each point in the array, thereby providing a three-dimensional color virtual model of the surface of the structure. A corresponding method for determining the surface topology and associated color of a structure is also provided.

Abstract translation: 提供了一种用于确定诸如齿段的结构的表面拓扑结构和相关联颜色的装置，所述结构包括扫描器，用于为沿着与深度方向基本正交的二维阵列的点提供深度数据;以及图像获取装置， 为阵列的每个点提供颜色数据，同时相对于结构的设备的空间布置基本上保持不变。 处理器组合阵列中每个点的颜色数据和深度数据，从而提供结构表面的三维颜色虚拟模型。 还提供了用于确定结构的表面拓扑和相关联颜色的相应方法。

公开(公告)号：US20120077282A1

公开(公告)日：2012-03-29

申请号：US13311164

申请日：2011-12-05

Applicant: Michael Katzlinger ,  Josef J. Atzler ,  Daniel M. Stock

Inventor： Michael Katzlinger ,  Josef J. Atzler ,  Daniel M. Stock

IPC: G01N21/75

CPC classification number: G01J3/02 ,  G01J3/0202 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0232 ,  G01J3/0235 ,  G01J3/0256 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/427 ,  G01J3/4406 ,  G01N21/6408 ,  G01N21/6428 ,  G01N21/6445 ,  G01N21/645 ,  G01N21/763 ,  G01N2021/1738 ,  G01N2021/6415 ,  G01N2021/6419 ,  G01N2021/6441 ,  G01N2021/6482 ,  G01N2201/024 ,  G01N2201/0618 ,  G01N2201/062 ,  G01N2201/0621 ,  G01N2201/0692 ,  G01N2201/0696

Abstract: A cartridge and cartridge system for use in an apparatus for analyzing a sample are provided. The system has a plurality of cartridges for different applications for a multimode instrument. The cartridges are removably engaged with a cartridge support of the apparatus in a “plug-in” format such that one cartridge may be removed from the apparatus and another cartridge may be easily installed. The cartridge support includes a plurality of cartridge positions that receive cartridges concurrently. One of the cartridges may be a luminescence cartridge that includes an integrated detector that is movable toward and away from a sample carrier of the apparatus, and thus toward and away from a sample located at the sample carrier.

Abstract translation: 提供了用于分析样品的装置中的盒和盒系统。 该系统具有用于多模仪器的不同应用的多个盒。 墨盒以“插入”格式与装置的墨盒支架可拆卸地接合，使得一个墨盒可以从设备中取出，另一墨盒可以容易地安装。 盒支架包括同时接收盒的多个盒位置。 其中一个盒可以是发光盒，其包括集成检测器，该检测器可朝向和远离装置的样品载体移动，并且因此朝向和离开位于样品载体处的样品。

公开(公告)号：US08144328B2

公开(公告)日：2012-03-27

申请号：US12418492

申请日：2009-04-03

Applicant: Vijayakumar C. Venugopal ,  Eric Pape ,  Jean-Paul Booth

Inventor： Vijayakumar C. Venugopal ,  Eric Pape ,  Jean-Paul Booth

IPC: G01N21/00

CPC classification number: G01N21/274 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/0294 ,  G01J3/443 ,  G01N21/68

Abstract: An arrangement for in-situ optical interrogation of plasma emission to quantitatively measure normalized optical emission spectra in a plasma chamber is provided. The arrangement includes a flash lamp and a set of quartz windows. The arrangement also includes a plurality of collimated optical assemblies, which is optically coupled to the set of quartz windows. The arrangement further includes a plurality of fiber optic bundles, which comprises at least an illumination fiber optic bundle, a collection fiber optic bundle, and a reference fiber optic bundle. The arrangement more over includes a multi-channel spectrometer, which is configured with at least a signal channel and a reference channel. The signal channel is optically coupled to at least the flash lamp, the set of quartz windows, the set of collimated optical assemblies, the illuminated fiber optic bundle, and the collection fiber optic bundle to measure a first signal.

Abstract translation: 提供了用于等离子体发射的原位光询问以定量测量等离子体室中的归一化光发射光谱的布置。 该装置包括闪光灯和一组石英窗。 该布置还包括多个准直的光学组件，其光耦合到该组石英窗口。 该布置还包括多个光纤束，其包括至少照明光纤束，收集光纤束和参考光纤束。 更多的布置包括多通道光谱仪，其被配置有至少一个信号通道和参考通道。 信号通道光学耦合到至少闪光灯，该组石英窗，该组准直光学组件，照明光纤束和收集光纤束以测量第一信号。

公开(公告)号：US08125625B2

公开(公告)日：2012-02-28

申请号：US12501449

申请日：2009-07-12

Applicant: Stephan Clark ,  Brett E Dahlgren

Inventor： Stephan Clark ,  Brett E Dahlgren

IPC: G01N21/00

CPC classification number: G01J3/02 ,  G01J3/0218 ,  G01J3/50 ,  G01J3/501 ,  G01J2003/468

Abstract: Hard copy re-emission color measurement system, comprising a light arrangement for emitting light onto a hard copy, a light detector arranged to detect light re-emitted by the hard copy, and a control circuit configured to process the detected re-emitted light. The light arrangement is arranged to separately and simultaneously emit a first light having wavelengths longer than an ultraviolet wavelength and a second light having wavelengths in the ultraviolet range. The light arrangement is provided with a light guide arranged to guide the first and second light on an at least partly overlapping region on a hard copy.

Abstract translation: 硬拷贝再发射颜色测量系统，包括用于将光发射到硬拷贝上的光布置;布置成检测由硬拷贝重新发射的光的光检测器;以及被配置为处理检测到的再发射光的控制电路。 光排列被布置成分开并同时发射波长长于紫外线波长的第一光和具有紫外范围波长的第二光。 光布置设置有导向器，布置成将第一和第二光引导到硬拷贝上的至少部分重叠的区域上。

公开(公告)号：US20120035442A1

公开(公告)日：2012-02-09

申请号：US13167445

申请日：2011-06-23

Applicant: Ishan Barman ,  Narahara Chari Dingari ,  Ramachandra Dasari ,  Michael Feld ,  Chae-Ryon Kong ,  David Feld ,  Alison Hearn ,  Jonathan Feld

Inventor： Ishan Barman ,  Narahara Chari Dingari ,  Ramachandra Dasari ,  Michael Feld ,  Chae-Ryon Kong ,  David Feld ,  Alison Hearn ,  Jonathan Feld

IPC: A61B5/1455

CPC classification number: A61B5/14532 ,  A61B5/1455 ,  A61B5/4312 ,  A61B5/444 ,  A61B2560/0223 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/0272 ,  G01J3/44 ,  G01N21/65 ,  G01N2201/129

Abstract: The present invention further relates to the selection of the specific filter combinations, which can provide sufficient information for multivariate calibration to extract accurate analyte concentrations in complex biological systems. The present invention also describes wavelength interval selection methods that give rise to the miniaturized designs. Finally, this invention presents a plurality of wavelength selection methods and miniaturized spectroscopic apparatus designs and the necessary tools to map from one domain (wavelength selection) to the other (design parameters). Such selection of informative spectral bands has a broad scope in miniaturizing any clinical diagnostic instruments which employ Raman spectroscopy in particular and other spectroscopic techniques in general.

Abstract translation: 本发明还涉及特定过滤器组合的选择，其可以提供足够的信息用于多变量校准以提取复杂生物系统中的精确分析物浓度。 本发明还描述了引起小型化设计的波长间隔选择方法。 最后，本发明提出了多种波长选择方法和小型化分光设备设计以及从一个域（波长选择）到另一个域（设计参数）映射的必要工具。 信息谱带的这种选择在使得特别采用拉曼光谱和其他光谱技术的任何临床诊断仪器的小型化方面具有广泛的范围。

公开(公告)号：US08102518B2

公开(公告)日：2012-01-24

申请号：US12801684

申请日：2010-06-21

Applicant: Roy C. Haught ,  Gary P. Klinkhammer ,  Frank J. Bussell

Inventor： Roy C. Haught ,  Gary P. Klinkhammer ,  Frank J. Bussell

IPC: G01J3/51 ,  G01N21/64

CPC classification number: G01J3/02 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/42 ,  G01J2003/1213 ,  G01N21/05 ,  G01N21/31 ,  G01N21/645

Abstract: A method and apparatus for monitoring water and other fluid systems is described. The fluid is continually monitored spectrophotometrically by measuring many optical parameters in an in-line, on-line system, which compensates for normal fluid changes while detecting abnormalities.

Abstract translation: 描述了用于监测水和其它流体系统的方法和装置。 通过在线式在线系统中测量许多光学参数，分光光度法连续监测流体，在检测异常时补偿正常的液体变化。