公开(公告)号：US10179070B2

公开(公告)日：2019-01-15

申请号：US14808851

申请日：2015-07-24

Applicant: AMO Manufacturing USA, LLC

Inventor： Ihor Berezhnyy ,  Anatoly Fabrikant ,  Guangming Dai ,  Benjamin Logan ,  Anthony Tang ,  Henry Price ,  Stephen Calebotta

IPC: A61F9/008 ,  G01J11/00 ,  G01J1/42 ,  G01J1/10 ,  G01J1/58 ,  A61B18/00 ,  A61B18/20

Abstract: Embodiments of the present invention generally describe systems, devices, and methods for directly measuring pulse profiles during pulse delivery. In some embodiment, the pulse profiles may be measured while the pulse is delivered to ablate a material. Embodiments, may calculate ablation spot parameters based on the pulse profiles and may refine one or more subsequent laser pulses based on deviations from the calculated ablation spot parameters from desired ablation spot parameters. In some embodiments, a fluence profiler is provided. The fluence profiler may measure a pulse profile of a laser pulse from a portion of the laser pulse. The fluence profiler may utilize a UV radiation energy sensor device and a camera-based imager. The measurements from the UV radiation energy sensor device and the camera-based imager may be combined and scaled to provide a measured pulse profile that corresponds to the delivered pulse.

公开(公告)号：US10012592B2

公开(公告)日：2018-07-03

申请号：US15722486

申请日：2017-10-02

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Adam Abate ,  John Lawrence Emhoff ,  Tony Hung ,  Adnan Moez Esmail ,  Sepehr Kiani ,  Pascaline Mary

IPC: G01J1/10 ,  G01J3/30 ,  G01N21/64 ,  G01N21/76 ,  G01N21/25 ,  C12Q1/6806

CPC classification number: G01N21/6486 ,  C12Q1/6806 ,  G01N21/255 ,  G01N21/76 ,  G01N2201/06113 ,  G01N2201/062 ,  C12Q2545/101 ,  C12Q2563/107 ,  C12Q2563/159 ,  C12Q2563/161 ,  C12Q2565/629

Abstract: The present invention generally pertains to methods and kits for managing the variation in spectroscopic intensity measurements through the use of a reference component. The reference component may comprise a reference spectroscopic substance and may be contained together with a sample of interest in a sample to be tested, wherein the sample of interest may comprise a sample spectroscopic substance. Each sample to be tested may be uniquely identified and, hence, “barcoded” by combinations of different colors and concentrations of spectroscopic substances, contained therein.

公开(公告)号：US09897540B2

公开(公告)日：2018-02-20

申请号：US15000842

申请日：2016-01-19

Applicant: Fu Tai Hua Industry (Shenzhen) Co., Ltd. ,  HON HAI PRECISION INDUSTRY CO., LTD.

Inventor： Chao-Hung Ma ,  Shen-Kang Li ,  Ning Duan ,  Zhi-Ling Chen

IPC: G01N21/55 ,  G01J1/18 ,  G01J1/10

CPC classification number: G01N21/55 ,  G01J1/10 ,  G01J1/18

Abstract: A material inspection apparatus includes a light source, a light receiver, a light converter, and a processing unit. The light source is configured to emit light to a surface of an object to be inspected. The light receiver is configured to receive light reflected from the surface of the object. The light converter is configured to convert the light received by the light receiver into an electric current. The processing unit is configured to determine, according to the electric current, a material of the surface of the object.

公开(公告)号：US09885614B2

公开(公告)日：2018-02-06

申请号：US14968237

申请日：2015-12-14

Applicant: BEIHANG UNIVERSITY

Inventor： Zheng Zheng ,  Xin Zhao ,  Lei Liu ,  Jiansheng Liu

IPC: G01J11/00 ,  G01J3/42 ,  G01J3/10 ,  G01J3/447 ,  G01J3/02 ,  G01J3/433 ,  G01J1/10 ,  G02F1/365 ,  H01S3/00 ,  G02F1/35 ,  G02F1/37 ,  H01S3/067 ,  H01S3/11 ,  H01S3/23 ,  H01S3/08

CPC classification number: G01J11/00 ,  G01J1/10 ,  G01J3/0224 ,  G01J3/0245 ,  G01J3/10 ,  G01J3/108 ,  G01J3/42 ,  G01J3/433 ,  G01J3/447 ,  G02F1/353 ,  G02F1/365 ,  G02F1/37 ,  G02F2203/13 ,  H01S3/0092 ,  H01S3/06791 ,  H01S3/0809 ,  H01S3/1106 ,  H01S3/1112 ,  H01S3/2391

Abstract: A method and a system for measuring an optical asynchronous sample signal. The system for measuring an optical asynchronous sampling signal comprises a pulsed optical source capable of emitting two optical pulse sequences with different repetition frequencies, a signal optical path, a reference optical path, and a detection device. Since the optical asynchronous sampling signal can be measured by merely using one pulsed optical source, the complexity and cost of the system are reduced. A multi-frequency optical comb system using the pulsed optical source and a method for implementing the multi-frequency optical comb are further disclosed.

公开(公告)号：US09347823B2

公开(公告)日：2016-05-24

申请号：US14166796

申请日：2014-01-28

Applicant: National Institute of Metrology, P.R.China

Inventor： Ruoduan Sun

IPC: G01J1/10 ,  G01J1/02 ,  G01J3/02 ,  G01J1/04

CPC classification number: G01J1/0295 ,  G01J1/0437 ,  G01J1/0462 ,  G01J3/0229 ,  G01J3/0254 ,  G01J3/0297

Abstract: The present invention discloses a method for measuring absolute value of non-linear error and an apparatus thereof. The method comprises: placing N reflecting plates jointed together at the sample port of the optical measuring instrument at the same time, wherein each of reflecting plate has a same covering area at the sample port; placing an aperture along light paths of the optical measuring instrument; adjusting the number of reflecting plates as used according to a position in the measuring range of the optical measuring instrument where the non-linear error is required to be measured; following every adjustment, acquiring the output results when the adjusted reflecting plates are placed at the sample port; performing a computation processing for non-linear error to the output results; and acquiring the non-linear error of the output results of the optical measuring instrument.

公开(公告)号：US09329121B2

公开(公告)日：2016-05-03

申请号：US13264419

申请日：2010-04-16

Applicant: Jens Moeller Jensen ,  Arun Krishna ,  Lars Munch ,  Rainer Buchner ,  Thomine Stolberg-Rohr ,  Henrik Gedde Moos

Inventor： Jens Moeller Jensen ,  Arun Krishna ,  Lars Munch ,  Rainer Buchner ,  Thomine Stolberg-Rohr ,  Henrik Gedde Moos

IPC: G01J1/00 ,  G01J1/10 ,  G01J5/02 ,  G01J5/10 ,  G01N21/3504 ,  G01J3/02 ,  G01J3/36 ,  G01N21/31 ,  G01J3/427 ,  G01J3/12

CPC classification number: G01N21/3504 ,  G01J1/00 ,  G01J1/10 ,  G01J3/02 ,  G01J3/027 ,  G01J3/36 ,  G01J3/427 ,  G01J5/02 ,  G01J5/10 ,  G01J2003/1213 ,  G01N21/314

Abstract: The invention relates to a sensor having a filter arrangement, downstream of which there is arranged a detector arrangement, and an evaluating device connected to the detector arrangement. The filter arrangement has at least a first filter, the suspect filter, and at least one second filter, the reference filter(s). The first filter is configured as a band pass filter allowing the passage of a first predetermined band, the suspect band. The at least one second filter is configured as a band pass filter allowing the passage of a second predetermined band(s), the reference band(s). The detector arrangement has at least one detector associated with at least one of the filters. The band passes reference filters are distributed above and below the band pass of the suspect filter. The sensor with advantage could be utilized within the IR band, and could advantageously be used to detect CO2.

Abstract translation: 本发明涉及一种具有滤波器装置的传感器，其下游设置有检测器装置，以及连接到检测器装置的评估装置。 过滤器装置至少具有第一过滤器，可疑过滤器和至少一个第二过滤器，参考过滤器。 第一滤波器被配置为允许第一预定频带（可疑频带）通过的带通滤波器。 至少一个第二滤波器被配置为带通滤波器，允许通过第二预定带（参考频带）。 检测器装置具有至少一个与至少一个滤波器相关的检测器。 带通过参考滤波器分布在可疑滤波器的带通上方和下方。 有利的传感器可以在IR带内使用，并且可以有利地用于检测CO 2。

公开(公告)号：US09243992B2

公开(公告)日：2016-01-26

申请号：US13132574

申请日：2009-12-01

Applicant: Henri Champseix ,  Olivier Magnin ,  Bernard Welmant

Inventor： Henri Champseix ,  Olivier Magnin ,  Bernard Welmant

IPC: G01N21/00 ,  G01J1/10 ,  G01N1/10 ,  G01N15/02 ,  G01N15/12 ,  G01N15/14 ,  G01N33/49 ,  G01N15/10 ,  G01N15/00

CPC classification number: G01N15/1209 ,  G01N15/1056 ,  G01N15/1227 ,  G01N15/14 ,  G01N15/1404 ,  G01N15/1429 ,  G01N15/1456 ,  G01N15/1459 ,  G01N15/1463 ,  G01N15/1484 ,  G01N33/4915 ,  G01N2015/008 ,  G01N2015/1037

Abstract: A method and a device employing the method of flow cytometry, preferably applicable but not limited to the counting and differentiation of leukocytes. It relates more particularly to the field of simplified haematology instruments with moderate operating costs. The method is characterized in that a technique of impedance measurement is used for identifying the particles whose trajectory did not pass through a predetermined optical measurement zone in order to process them selectively, thus avoiding the use of sheath fluids for guiding the particles towards the measurement zone.

Abstract translation: 采用流式细胞术方法的方法和装置，优选适用于但不限于白细胞的计数和分化。 它更具体地涉及具有中等操作成本的简化血液学仪器领域。 该方法的特征在于，使用阻抗测量技术来识别其轨迹未经过预定的光学测量区域的颗粒，以便选择性地处理它们，从而避免使用鞘液将颗粒引向测量区域 。

公开(公告)号：US08901495B2

公开(公告)日：2014-12-02

申请号：US13076107

申请日：2011-03-30

Applicant: Charles G. Stevens ,  Joseph W. Tringe

Inventor： Charles G. Stevens ,  Joseph W. Tringe

IPC: G01J1/10 ,  G01J3/10 ,  G01J3/453

CPC classification number: G01J3/453 ,  G01J3/10 ,  G01J3/4338 ,  G01N21/35

Abstract: In one embodiment, a heterodyne detection system for detecting light includes a first input aperture adapted for receiving a first light from a scene input, a second input aperture adapted for receiving a second light from a local oscillator input, a broadband local oscillator adapted for providing the second light to the second input aperture, a dispersive element adapted for dispersing the first light and the second light, and a final condensing lens coupled to an infrared detector. The final condensing lens is adapted for concentrating incident light from a primary condensing lens onto the detector, and the detector is a square-law detector capable of sensing the frequency difference between the first light and the second light. More systems and methods for detecting light are disclosed according to more embodiments.

Abstract translation: 在一个实施例中，用于检测光的外差检测系统包括适于接收来自场景输入的第一光的第一输入孔，适于接收来自本地振荡器输入的第二光的第二输入孔，适于提供 第二光到第二输入孔，适于分散第一光和第二光的分散元件，以及耦合到红外检测器的最终聚光透镜。 最终聚光透镜适用于将来自主聚焦透镜的入射光集中到检测器上，检测器是能够检测第一光与第二光之间的频差的平方律检测器。 根据更多实施例公开了用于检测光的更多系统和方法。

公开(公告)号：US20120218546A1

公开(公告)日：2012-08-30

申请号：US13449389

申请日：2012-04-18

Applicant: Kazuhiro Ogawa ,  Hiroto Shibuya ,  Shigeyuki Yamaguchi ,  Ryousuke Miyoshi ,  You Sasaki ,  Hiroyuki Konno ,  Jeffrey Robert DeBoer

Inventor： Kazuhiro Ogawa ,  Hiroto Shibuya ,  Shigeyuki Yamaguchi ,  Ryousuke Miyoshi ,  You Sasaki ,  Hiroyuki Konno ,  Jeffrey Robert DeBoer

IPC: G01J1/10

CPC classification number: G01S7/497 ,  G01S7/4812 ,  G01S17/42 ,  G01S17/89

Abstract: A laser scanner measuring system is disclosed, which has a laser scanner and a calibration target. The laser scanner comprises a light emitting element for emitting a pulsed laser beam, a rotary projecting unit for projecting the pulsed laser beam, a distance measuring unit, and a control unit for driving and controlling the light emitting element and the distance measuring unit. The calibration target has a reflection sector with a known shape and with high reflectance and is installed at a known position. In use, there is a step for judging a reflected pulsed laser beam from the reflection sector by detecting a level of light quantity, a step for determining a center position of the reflection sector based on the result of the judgment, and a step for calibrating the laser scanner measuring system based on the determined center position and on the known position.

Abstract translation: 公开了一种具有激光扫描仪和校准目标的激光扫描仪测量系统。 激光扫描器包括用于发射脉冲激光束的发光元件，用于投射脉冲激光束的旋转投影单元，距离测量单元和用于驱动和控制发光元件和距离测量单元的控制单元。 校准目标具有已知形状和高反射率的反射扇区，并且安装在已知位置。 在使用中，存在通过检测光量水平来判断来自反射扇区的反射脉冲激光束的步骤，基于判断结果确定反射扇区的中心位置的步骤，以及校准步骤 激光扫描仪测量系统基于确定的中心位置和已知位置。

公开(公告)号：US20120133930A1

公开(公告)日：2012-05-31

申请号：US13360532

申请日：2012-01-27

Applicant: Jason CHRISTIANSEN ,  Robert Pinard ,  Maciej P. Zerkowski ,  Gregory R. Tedeschi

Inventor： Jason CHRISTIANSEN ,  Robert Pinard ,  Maciej P. Zerkowski ,  Gregory R. Tedeschi

IPC: G01J1/10

CPC classification number: G01N21/6486 ,  G01N21/276 ,  G01N21/278 ,  G01N21/6458 ,  G01N2021/6439

Abstract: Methods and apparatus for standardizing quantitative measurements from a microscope system. The process includes a calibration procedure whereby an image of a calibration slide is obtained through the optics of the microscope system. The calibration slide produces a standard response, which can be used to determine a machine intrinsic factor for the particular system. The machine intrinsic factor can be stored for later reference. In use, images are acquired of a target sample and of the excitation light source. The excitation light source sample is obtained using a calibration instrument configured to sample intensity. The calibration instrument has an associated correction factor to compensate its performance to a universally standardized calibration instrument. The machine intrinsic factor, sampled intensity, and calibration instrument correction factor are usable to compensate a quantitative measurement of the target sample in order to normalize the results for comparison with other microscope systems.

Abstract translation: 用于从显微镜系统标准化定量测量的方法和装置。 该过程包括校准过程，由此通过显微镜系统的光学器件获得校准载玻片的图像。 校准滑块产生标准响应，可用于确定特定系统的机器固有因素。 机器固有因素可以存储供以后参考。 在使用中，获取目标样本和激发光源的图像。 使用配置为采样强度的校准仪器获得激发光源样品。 校准仪器具有相关的校正因子，以补偿其对普遍标准化校准仪器的性能。 机器固有因子，采样强度和校准仪器校正因子可用于补偿目标样品的定量测量，以便将结果归一化以与其他显微镜系统进行比较。