公开(公告)号：US20230343571A1

公开(公告)日：2023-10-26

申请号：US18339510

申请日：2023-06-22

Applicant: Thermo Fisher Scientific (Bremen) GmbH

Inventor： Henning WEHRS ,  Johannes SCHWIETERS ,  Gerhard JUNG

IPC: H01J49/06 ,  H01J49/00 ,  H01J49/02 ,  H01J49/10 ,  H01J49/42 ,  F16K1/20

CPC classification number: H01J49/063 ,  H01J49/0077 ,  H01J49/022 ,  H01J49/065 ,  H01J49/067 ,  H01J49/105 ,  H01J49/421 ,  H01J49/068 ,  H01J49/4215 ,  F16K1/2007 ,  H01J49/005

Abstract: An ion optical arrangement (1) for use in a mass spectrometer comprises electrodes (11, 12, 14) comprising a multipole arrangement defining an ion optical axis, and a voltage source for providing voltages to the electrodes to produce electric fields. The ion optical arrangement is configured for producing a radio frequency electric focusing field for focusing ions on the ion optical axis. The radio frequency electric focusing field has a varying frequency so as to reduce any mass dependence of ion trajectories through the ion optical arrangement. The ion optical arrangement may further he configured for producing a static electric field in response to a DC bias voltage applied to the multipole arrangement. A superimposed varying electric field may be produced by superimposing an AC voltage upon the DC bias voltage.

公开(公告)号：US20230335385A1

公开(公告)日：2023-10-19

申请号：US18297303

申请日：2023-04-07

Applicant: GLASS EXPANSION PTY. LIMITED

Inventor： David Sultana ,  Danny Brezni ,  Terrance Hettipathirana ,  Bill Farrell ,  Anthony Le Breton

IPC: H01J49/04 ,  H01J49/10

CPC classification number: H01J49/045 ,  H01J49/105

Abstract: A flow control device for aerosolised sample delivery in an inductively coupled plasma (ICP) analytical system is provided. The device includes a body that at least in part defines a sample flow separating region, the sample flow separating region having a longitudinal flow direction and having an upstream end through which the aerosolised sample enters and a downstream end through which a modified aerosolised sample exits. The body further includes an injection duct having an opening adjacent to the sample flow separating region, the injection duct configured to direct a stream of gas in an injection direction to the sample flow separating region. The injection direction is angled relative to the longitudinal flow direction such that, upon introduction of the stream of gas through the opening, a vortex flow is generated in the sample flow separating region, the vortex flow having a direction counter to the direction of flow of the aerosolised sample to provide control of droplet size in the modified aerosolised sample.

公开(公告)号：US20230273174A1

公开(公告)日：2023-08-31

申请号：US18128583

申请日：2023-03-30

Applicant: Eion Corp.

Inventor： Adam Wolf ,  Elliot Suk-Hyun Chang ,  Alan Robert Tank

IPC: G01N33/24 ,  H01J49/10 ,  C09K17/12 ,  C09K11/77

CPC classification number: G01N33/24 ,  H01J49/105 ,  C09K17/12 ,  C09K11/77

Abstract: The present disclosure relates to methods of verifying enhanced rock weathering using immobile trace elements found within a mineral amendment. Further disclosed are mineral amendments that enable enhanced rock weathering.

公开(公告)号：US20230260773A1

公开(公告)日：2023-08-17

申请号：US17804321

申请日：2022-05-27

Applicant: National Institutes for Food and Drug Control ,  Wang Jing Hospital of CACMS (Orthopedics Research Institute of CACMS) ,  Tongliao Market Inspection and Testing Center

Inventor： Shuangcheng Ma ,  Tiantian Zuo ,  Jia Zhu ,  Qinghui Song ,  Wanqiang Zhang ,  Jishuang Wang ,  Haiyan Wang ,  Lei Sun ,  Hongyu Jin ,  Qi Wang ,  Jianbo Yang ,  Dejuan Kong ,  Shuai Kang ,  Jiandong Yu

IPC: H01J49/10 ,  H01J49/00

CPC classification number: H01J49/105 ,  H01J49/0036

Abstract: The present disclosure provides a method for constructing a correlation model between relative bioavailability and bioaccessibility of cadmium in earthworm, belonging to the technical field of cadmium detection in earthworms. The method includes the following steps: determination of relative bioavailability of cadmium in earthworms, determination of bioaccessibility of cadmium in the earthworm based on an in vitro physiologically-based extraction test (PBET) method, and construction of a correlation model between the relative bioavailability and the bioaccessibility of cadmium in the earthworm. The method enables to directly put the bioaccessibility obtained by the in vitro method into a regression equation to obtain the bioavailability of cadmium in subsequent studies. The method eliminates a need for animal experiments in follow-up researches, saves resources to the greatest extent, and provides a new idea for objectively and scientifically evaluating the health risk of cadmium in the earthworm to human bodies.

公开(公告)号：US11694914B2

公开(公告)日：2023-07-04

申请号：US17968124

申请日：2022-10-18

Applicant: Elemental Scientific, Inc.

Inventor： Tyler Yost ,  Daniel R. Wiederin ,  Beau A. Marth ,  Jared Kaser ,  Jonathan Hein ,  Jae Seok Lee ,  Jae Min Kim ,  Stephen H. Sudyka

IPC: H01L21/67 ,  H01L21/66 ,  G01N21/73 ,  G01N33/00 ,  H01L21/677 ,  H01J49/10 ,  H01J49/00

CPC classification number: H01L21/6719 ,  G01N21/73 ,  H01J49/105 ,  H01L21/6708 ,  H01L21/6715 ,  H01L21/67051 ,  H01L21/67126 ,  H01L21/67259 ,  H01L21/67748 ,  H01L21/67772 ,  H01L22/14 ,  H01L22/34 ,  G01N2033/0095 ,  H01J49/00 ,  H01L22/12

Abstract: Systems and methods are described for integrated decomposition and scanning of a semiconducting wafer, where a single chamber is utilized for decomposition and scanning of the wafer of interest.

公开(公告)号：US11651945B2

公开(公告)日：2023-05-16

申请号：US17480094

申请日：2021-09-20

Applicant: UT-Battelle, LLC

Inventor： Vilmos Kertesz ,  John F. Cahill

IPC: H01J49/00 ,  H01J49/04 ,  H01J49/16 ,  H01J49/14 ,  H01J49/10

CPC classification number: H01J49/0445 ,  H01J49/0031 ,  H01J49/105 ,  H01J49/145 ,  H01J49/161 ,  H01J49/165

Abstract: A system for the mass spectrometry analysis of an analyte includes a droplet ejection device, a spray head comprising a spray tip for ejecting the solvent as a spray, and a solvent delivery conduit for delivering solvent to the spray tip. The spray head includes a droplet inlet opening communicating with the surrounding atmosphere for receiving liquid droplets comprising the analyte. The droplet ejection device selectively ejects a liquid analyte droplet comprising the analyte through a surrounding atmosphere and the droplet inlet opening into a solvent flowing through the solvent delivery conduit. A method for the mass spectrometry analysis of an analyte is also disclosed.

公开(公告)号：US20190221416A1

公开(公告)日：2019-07-18

申请号：US16292815

申请日：2019-03-05

Applicant: Thermo Fisher Scientific (Bremen) GmbH

Inventor： Johannes SCHWIETERS ,  Henning WEHRS

IPC: H01J49/10 ,  H01J49/00

CPC classification number: H01J49/105 ,  H01J49/0027

Abstract: Methods of determining isobaric interference during mass analysis in a mass spectrometer are provided. The methods comprise comparing interference-free reaction profiles of a chemical species to reaction profiles of the same chemical species that may comprise isobaric interference, wherein a determination of a difference between the profiles is an indication of isobaric interference being present. Methods of quantifying isobaric interference are also provided, including methods of correcting isotope ratios determined in the presence of isobaric interference.

公开(公告)号：US20190064135A1

公开(公告)日：2019-02-28

申请号：US15549989

申请日：2016-09-05

Applicant: FOOD INSPECTION CENTER OF CIQ-SHENZHEN ,  SHENZHEN ACADEMY OF INSPECTION AND QUARANTINE

Inventor： Liqi XIE ,  Hao WU ,  Zhi YAN ,  Bo CHEN ,  Xiaolei JIN ,  Baohui JIN ,  Xuehai BIAN ,  Xu ZHAO

IPC: G01N33/14 ,  G01N30/02

CPC classification number: G01N33/146 ,  G01N30/02 ,  G01N30/8675 ,  G01N33/143 ,  G01N2030/025 ,  H01J49/105

Abstract: The present application provides a method for tracing wine origin based on multielements and stable isotopes, comprising the steps of:1) collecting wine samples from a plurality of origins;2) filtering each of the wine samples collected in step 1) using a pore size of 0.22 μm aqueous filter membrane, and pouring 1.5 ml of a filtrate into an autosampler vial for carbon stable isotope ratio analysis of ethanol and glycerol; pouring 0.3 ml of the wine sample into a 12 ml glass tube with stopper for analyzing oxygen stable isotopes in the water; and pouring 0.5 ml of the wine sample into a 15 ml centrifuge tube, and adding 0.5 ml of concentrated HNO3, performing digestion overnight, and diluting to a constant volume of 10 ml to be tested;3) performing carbon stable isotope analysis, oxygen stable isotope ratio analysis and elemental analysis, respectively;4) utilizing information of the origins of the wine samples and analytical data of step 3) to perform statistical modeling to obtain a wine origin discrimination model coefficient matrix and a corresponding predicted accuracy rate of the origin discrimination;5) performing origin discrimination by using an unknown sample in the model, and ultimately determining attributes of the wine origin.

公开(公告)号：US20180366310A1

公开(公告)日：2018-12-20

申请号：US16062932

申请日：2016-12-14

Applicant: PLASMION GMBH

Inventor： Jan-Christoph WOLF

IPC: H01J49/10 ,  H01J49/00 ,  H05H1/24

CPC classification number: H01J49/105 ,  H01J49/0031 ,  H05H1/2406 ,  H05H2001/2412 ,  H05H2001/2431 ,  H05H2001/245

Abstract: The present invention relates to the technical field of ionizing a gaseous substance, in particular the ionizing or ionization of a gaseous substance in preparation for its analysis. A device is intended to make a discharge gas and a test substance ionizable in a flow-through mode without essentially destroying or fragmenting the sample substance. In order to avoid a high expenditure in terms of construction and equipment, the device is intended to be usable under ambient conditions and to ensure a high sensitivity in a possible analysis of an ionized substance. To this end, an ionizing device is used for flow-through ionization of a discharge gas and of a sample substance at an absolute pressure of more than 40 kPa in the ionizing device during ionization. The ionizing device comprises an inlet, an outlet, a first electrode, a dielectric element and a second electrode. The dielectric element is configured in the shape of a hollow body having an inner side and an outer side and it allows a flow of the discharge gas and of the sample substance therethrough in a flow direction. The first electrode is arranged outside of the outer side of the dielectric element. The second electrode is arranged, at least sectionwise, inside the dielectric element, is surrounded by the inner side of the dielectric element perpendicularly to the flow direction, and allows a flow of the discharge gas and of the sample substance therethrough or therearound. A distance in or contrary to the flow direction exists between the associated ends of the first and second electrodes and lies between -5 mm to 5 mm. A dielectric barrier discharge is establishable in a dielectric barrier discharge region by applying a voltage between the first and second electrodes so as to ionize the discharge gas or the sample substance.

公开(公告)号：US20180174809A1

公开(公告)日：2018-06-21

申请号：US15837188

申请日：2017-12-11

Applicant: Thermo Fisher Scientific (Bremen) GmbH

Inventor： Thorben SCHUETHE

IPC: H01J49/00

CPC classification number: H01J49/0031 ,  F15B13/00 ,  G01F1/00 ,  G01F25/0053 ,  G05D7/00 ,  G05D7/03 ,  H01J49/005 ,  H01J49/105 ,  H01J49/24

Abstract: The present invention relates to a gas inlet system for an analytical apparatus. The gas inlet system comprises switchable flow restrictions for regulating gas flow rate. The invention also provides a system for calibrating gas flow rate in gas inlet systems, the system comprising a calibration line that comprises a gas flow meter, and that is arranged downstream of gas flow controllers in the gas inlet system. Methods of adjusting gas flow rates and methods of calibrating gas flow rates are also provided.