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公开(公告)号:US12087567B2
公开(公告)日:2024-09-10
申请号:US18339510
申请日:2023-06-22
Applicant: Thermo Fisher Scientific (Bremen) GmbH
Inventor: Henning Wehrs , Johannes Schwieters , Gerhard Jung
CPC classification number: H01J49/063 , F16K1/2007 , H01J49/005 , H01J49/0077 , H01J49/022 , H01J49/065 , H01J49/067 , H01J49/068 , H01J49/105 , H01J49/421 , H01J49/4215
Abstract: An ion optical arrangement (1) for use in a mass spectrometer comprises electrodes (11, 12, 14) comprising a multipole arrangement defining an ion optical axis, and a voltage source for providing voltages to the electrodes to produce electric fields. The ion optical arrangement is configured for producing a radio frequency electric focusing field for focusing ions on the ion optical axis. The radio frequency electric focusing field has a varying frequency so as to reduce any mass dependence of ion trajectories through the ion optical arrangement. The ion optical arrangement may further be configured for producing a static electric field in response to a DC bias voltage applied to the multipole arrangement. A superimposed varying electric field may be produced by superimposing an AC voltage upon the DC bias voltage.
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公开(公告)号:US12080535B2
公开(公告)日:2024-09-03
申请号:US16886288
申请日:2020-05-28
Applicant: Thermo Finnigan LLC
Inventor: Jesse D. Canterbury , Graeme C. McAlister
CPC classification number: H01J49/022 , H01J49/005 , H01J49/065 , H01J49/067 , H01J49/10 , H01J49/4225
Abstract: A mass spectrometer system, comprises: an ion source; a first and a second multipole apparatus; one or more ion gates or ion lenses between the first and second multipole apparatuses; at least one power supply configured to provide voltages to electrodes of the ion source, the mass analyzer, the first and second multipole apparatuses and the one or more ion gates or ion lenses; and a computer or electronic controller electrically coupled to the at least one power supply, wherein the computer or electronic controller comprises computer-readable instructions that are operable to cause the at least one power supply to supply voltages to the electrodes that cause transfer of ions from the first multipole apparatus to the second multipole apparatus, wherein a duration of a time allotted for completion of the transfer of the ions is dependent upon one or more properties of the ions being transferred.
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公开(公告)号:US20240274429A1
公开(公告)日:2024-08-15
申请号:US18568417
申请日:2022-06-09
Applicant: DH Technologies Development Pte. Ltd.
Inventor: Eric Thomas DZIEKONSKI
CPC classification number: H01J49/4245 , H01J49/0009 , H01J49/0031 , H01J49/027 , H01J49/065 , H01J49/4255 , H01J49/426
Abstract: Systems and methods described herein provide for the injection of ions into an ELIT at a variety of kinetic energies such that the ions turn around at various locations. In certain aspects, such systems and methods for operating an ELIT may reduce ion density at the turning points to reduce the impact of the space charge effect. Various aspects of the present teachings also provide for the design or optimization of the ELIT electrode spacing and/or injection potentials to reduce the impact of the space charge effect. In some related aspects, the ELIT may additionally provide time-focusing of the various ion groups at the detector as they oscillate along their respective path lengths.
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公开(公告)号:US12057306B2
公开(公告)日:2024-08-06
申请号:US17312900
申请日:2019-12-09
Applicant: DH TECHNOLOGIES DEVELOPMENT PTE. LTD.
Inventor: Eric Thomas Dziekonski
CPC classification number: H01J49/4245 , H01J49/065 , H01J49/027
Abstract: An ELIT includes voltage sources (1101), switches (1102), a first set of electrode plates (1110) aligned along a central axis, and a second set of electrode plates (1120) aligned along the central axis with the first set. A first group of plates (310, 320; 810, 820) of the first set and the second set is positioned to trap ions within a first path length (340, 940). A second group of plates (410, 420) of the first set and the second set is positioned to trap ions within a shorter second path length (440, 1040). The switches select the first path length by applying voltages from the voltage sources to the first set and the second set that cause the first group of plates to trap ions within the first path length. Alternatively, the switches can select the second path length by applying voltages that cause the second group of plates to trap ions within the second path length.
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公开(公告)号:US20240234116A1
公开(公告)日:2024-07-11
申请号:US18150645
申请日:2023-01-05
Applicant: Volatylix, Inc.
Inventor: Kenneth A. MARKOSKI , Erkinjon G. NAZAROV , Clayton J. MORRIS II
IPC: H01J49/02 , G01N27/622
CPC classification number: H01J49/022 , G01N27/622 , H01J49/025
Abstract: An integrated oscillating field ion spectrometry device includes an ionization segment, filtering segment, and detection segment arranged in order. The filtering segment is located after the ionization segment and the detection segment is located after the filtering segment in the carrier gas flow direction. The ionization segment includes an ionizing tool and ionization region electrodes. The carrier gas moves material vapor through the ionizing tool to ionize the material vapor. Two parallel filter electrodes of the filtering segment that receive first DC voltages of opposite polarity and an RF oscillating voltage, filter ions from the carrier gas. Two parallel detector electrodes in the detection segment that are connected to a detection system receive second DC voltages. Ion guidance electrodes surround a periphery of the detector electrodes. The DC voltages and the RF oscillating voltage are selected to optimize detection of the specific ions of interest for a particular application.
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公开(公告)号:US20240192717A1
公开(公告)日:2024-06-13
申请号:US18556200
申请日:2022-04-29
Applicant: DH Technologies Development Pte. Ltd.
Inventor: Martian D. DIMA , Graham Arthur LEITH
CPC classification number: G05F3/16 , H01J49/022 , H01J49/40
Abstract: In some disclosed example embodiments, an apparatus, such as an ion detector or ion optics in a mass spectrometer, includes a power supply having two terminals and configured to provide a voltage of a first value between the two terminals, and a voltage regulator connected between the two terminals of the power supply. The voltage regulator includes a varistor, such as a metal-oxide varistor (MOV), and a current limiting circuit, such as a resistance device, connected in series with the varistor. The current limiting circuit is configured to bias the varistor to operate continuously in a breakdown mode. The apparatus can further include electrodes, such as those configured to influence flight of charged particles, with at least one of the electrodes connected to one end of the varistor, and at least another one of the electrodes connected to the other end of the varistor.
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公开(公告)号:US11984309B1
公开(公告)日:2024-05-14
申请号:US17334458
申请日:2021-05-28
Applicant: MICROPLASMA SYSTEMS, LLC
Inventor: James Joseph Alberti , Erkinjon G. Nazarov , Zev Litvak
IPC: H01J49/10 , G01N27/624 , H01J49/02 , H05H1/24
CPC classification number: H01J49/10 , G01N27/624 , H01J49/022 , H05H1/2406
Abstract: A non-radioactive homogenous plasma ion source that is power efficient with greater electrode life longevity and performance (homogenous low temperature plasma for ion formation, stability, robustness) than alternative non-radioactive ion sources for generating analyte ions of either positive or negative charge. Its compact design minimizes the spacing between electrodes, reducing the power requirements needed to ignite and maintain plasma levels. The non-radioactive plasma ion source generally comprises a housing for retaining a uniquely designed ion source that generates a uniform distribution of plasma to maximize the generation of ions at a lower plasma temperature to minimize undesirable nitrogen oxide and ozone gasses, at least one planar electrode in one embodiment, a mounting head with a gas exhaust, and a chamber with a counterflow gas inlet, and an analyte gas inlet. The non-radioactive plasma source improves ion source reliability over existing non-radioactive sources that are less efficient with reduced electrode life longevity.
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公开(公告)号:US20240128071A1
公开(公告)日:2024-04-18
申请号:US18491399
申请日:2023-10-20
Applicant: Micromass UK Limited
Inventor: Zoltán TAKÁTS , Júlia BALOG , Steven Derek PRINGLE , Tamás KARANCSI , Michael Raymond MORRIS , Lajos GÖDÖRHÁZY , Dániel SZALAY , Dániel SIMON
IPC: H01J49/04 , A61B1/04 , A61B1/273 , A61B5/00 , A61B5/01 , A61B5/0507 , A61B5/055 , A61B6/03 , A61B8/13 , A61B10/00 , A61B10/02 , A61B17/00 , A61B17/32 , A61B18/00 , A61B18/04 , A61B18/14 , A61B18/18 , A61B18/20 , A61B90/13 , A61F13/38 , C12Q1/02 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/22 , G01N3/00 , G01N9/00 , G01N27/623 , G01N27/624 , G01N30/72 , G01N33/487 , G01N33/68 , G01N33/92 , H01J49/00 , H01J49/02 , H01J49/06 , H01J49/10 , H01J49/14 , H01J49/16 , H01J49/24 , H01J49/26
CPC classification number: H01J49/049 , A61B1/041 , A61B1/2736 , A61B5/0066 , A61B5/0075 , A61B5/015 , A61B5/0507 , A61B5/055 , A61B6/032 , A61B6/037 , A61B8/13 , A61B10/00 , A61B10/0041 , A61B10/0233 , A61B10/0283 , A61B17/00 , A61B17/320068 , A61B18/00 , A61B18/04 , A61B18/042 , A61B18/14 , A61B18/1445 , A61B18/1815 , A61B18/20 , A61B90/13 , A61F13/38 , C12Q1/025 , C12Q1/04 , C12Q1/18 , C12Q1/24 , G01N1/2202 , G01N3/00 , G01N9/00 , G01N27/623 , G01N27/624 , G01N30/724 , G01N33/487 , G01N33/6848 , G01N33/6851 , G01N33/92 , H01J49/0004 , H01J49/0027 , H01J49/0031 , H01J49/0036 , H01J49/025 , H01J49/0404 , H01J49/0409 , H01J49/0422 , H01J49/044 , H01J49/0445 , H01J49/0459 , H01J49/0463 , H01J49/0468 , H01J49/061 , H01J49/068 , H01J49/10 , H01J49/14 , H01J49/16 , H01J49/164 , H01J49/24 , H01J49/26 , G16B20/00
Abstract: An apparatus is disclosed comprising a first device for generating aerosol, smoke or vapour from one or more regions of a target, an inlet conduit to an ion analyser or mass spectrometer, the inlet conduit having an inlet through which the aerosol, smoke or vapour passes, and a Venturi pump arrangement arranged and adapted to direct the aerosol, smoke or vapour towards the inlet.
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公开(公告)号:US20240128070A1
公开(公告)日:2024-04-18
申请号:US18380019
申请日:2023-10-13
Applicant: Kimia Analytics Inc. , Quadrocore Corp.
Inventor: Sina ALAVI , Gholamreza JAVAHERY , Dmitry VALYAEV , Victor TITOV
CPC classification number: H01J49/0095 , H01J49/027 , H01J49/061
Abstract: The present invention is ion detection method for mass spectrometer. An electron multiplier is coupled with a conversion dynode for the detection of positive and negative ions. The aperture of the present system is ungrounded. As the ions (positive or negative) approach and go through the aperture, they induce an image current into the aperture plate which can be amplified and measured by a processing circuit. The magnitude of the image current is directly proportional to the number density, speed, charge, and polarity of ions flowing through the aperture. The measured image current is used as a means to switch between various detection modes. The measured current is calibrated and used as a reference to automatically switch between analog/counting modes, positive/negative ion detection, or various types of detectors implemented in the ion detection system.
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公开(公告)号:US20240112899A1
公开(公告)日:2024-04-04
申请号:US18447640
申请日:2023-08-10
Applicant: SHIMADZU CORPORATION
Inventor: Shiro MIZUTANI
CPC classification number: H01J49/0009 , H01J49/022 , H01J49/4215
Abstract: A power supply device applies a voltage to a quadrupole mass filter. The power supply device has a main substrate and a wave-detection substrate. The main substrate includes a detector. The wave-detection substrate includes a wave detector and an identifier. The wave detector detects an AC component of a voltage to be applied to the quadrupole mass filter as a wave-detection voltage. The identifier outputs identification information of the wave detector defined in correspondence with the configuration of a rectifying device of the wave detector. The detector detects identification information output by the identifier, and supplies the detected identification information to a corrector that corrects a deviation of voltage caused by a leakage current of the rectifying device.
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