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    OPTICAL EMISSION ANALYZER
    281.
    发明申请
    OPTICAL EMISSION ANALYZER 有权
    光学排放分析仪

    公开(公告)号：US20100208255A1

    公开(公告)日：2010-08-19

    申请号：US12676096

    申请日：2007-09-04

    Applicant: Haruki Osa

    Inventor： Haruki Osa

    IPC: G01N21/67

    CPC classification number: G01N21/67 ,  G01J3/10

    Abstract: An optical emission analyzer is provided with a circuit-closing switch (56) for changing the state of an arc-generating circuit 5 between the closed state and the open state and a reverse-blocking diode (55) for preventing a spark current from flowing into the circuit-closing switch (56). The circuit-closing switch (56) is turned on before the beginning of a spark discharge between a discharge electrode (31) and a sample (32) to initiate excitation of a coil (53). Consequently, the excitation current of the coil (53) can be increased to a target value within the duration of the spark discharge without using a low-inductance coil or increasing the switching frequency of a switching element (52).

    Abstract translation: 光发射分析仪设置有用于改变在闭合状态和打开状态之间的电弧发生电路5的状态的闭路开关（56）和用于防止火花电流流动的反向阻挡二极管（55） 进入电路关闭开关（56）。 在放电电极（31）和样品（32）之间的火花放电开始之前，电路关闭开关（56）导通，以启动线圈（53）的激励。 因此，不用使用低电感线圈或提高开关元件（52）的开关频率，可以使线圈（53）的励磁电流在火花放电的持续时间内增加到目标值。

    LIGHTING DESIGN OF HIGH QUALITY BIOMEDICAL DEVICES
    282.
    发明申请
    LIGHTING DESIGN OF HIGH QUALITY BIOMEDICAL DEVICES 有权
    高品质生物医学设备的照明设计

    公开(公告)号：US20100187440A1

    公开(公告)日：2010-07-29

    申请号：US12691601

    申请日：2010-01-21

    Applicant: Claudia B. Jaffe ,  Steven M. Jaffe ,  Arlie R. Conner

    Inventor： Claudia B. Jaffe ,  Steven M. Jaffe ,  Arlie R. Conner

    IPC: G01J1/58

    CPC classification number: G01N21/64 ,  G01J1/58 ,  G01J3/10 ,  G02B6/0003

    Abstract: The invention relates to a plurality of light sources to power a variety of applications including microarray readers, microplate scanners, microfluidic analyzers, sensors, sequencers, Q-PCR and a host of other bioanalytical tools that drive today's commercial, academic and clinical biotech labs.

    Abstract translation: 本发明涉及多种光源，用于驱动各种应用，包括微阵列阅读器，微孔板扫描仪，微流控分析仪，传感器，定序器，Q-PCR以及驱动当今商业，学术和临床生物技术实验室的许多其他生物分析工具。

    Method and apparatus for the generation and control of multiple near-field light sources at subwavelength resolution
    283.
    发明授权
    Method and apparatus for the generation and control of multiple near-field light sources at subwavelength resolution 有权
    用于在亚波长分辨率下生成和控制多个近场光源的方法和装置

    公开(公告)号：US07759630B2

    公开(公告)日：2010-07-20

    申请号：US11645827

    申请日：2006-12-26

    Applicant: Hendrik F. Hamann ,  Chie Ching Poon ,  Timothy Carl Strand

    Inventor： Hendrik F. Hamann ,  Chie Ching Poon ,  Timothy Carl Strand

    IPC: H01J3/14 ,  H01J5/16

    CPC classification number: G01Q60/22 ,  G01J3/10 ,  G11B7/1387 ,  Y10S977/892

    Abstract: Methods and devices for generating multiple, closely spaced, independently controlled near-field light sources are disclosed. By providing an aperture having at least two, orthogonally oriented ridge structures, two or more closely spaced near-field light sources can be generated by controlling the polarization direction of the illuminating radiation. Control of the shape of the aperture, and relative dimensions of the ridge structures allows optimization of the relative intensities of the near-field sources.

    Abstract translation: 公开了用于产生多个，紧密间隔的独立控制的近场光源的方法和装置。 通过提供具有至少两个正交定向的脊结构的孔，可以通过控制照明辐射的偏振方向来产生两个或更多个紧密间隔的近场光源。 孔的形状的控制和脊结构的相对尺寸允许优化近场源的相对强度。

    SPECTROPHOTOMETER AND METHOD
    285.
    发明申请
    SPECTROPHOTOMETER AND METHOD 有权
    分光光度计和方法

    公开(公告)号：US20100148083A1

    公开(公告)日：2010-06-17

    申请号：US12594249

    申请日：2008-04-03

    Applicant: Chris Brown ,  Brain T. Pridham ,  John Peter Coales

    Inventor： Chris Brown ,  Brain T. Pridham ,  John Peter Coales

    IPC: G01N21/55 ,  G01N21/33 ,  G01N21/25

    CPC classification number: G01J3/02 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/26 ,  G01J3/2803 ,  G01J3/50 ,  G01J3/501 ,  G01J2003/104

    Abstract: A spectrophotometer includes a plurality of LEDs arranged in a circular array, each having a calibrated power input determined by the use of pulse width modulation and each having a unique wavelength band determined by the utilization of a unique fluorescent phosphor coating or lens. At least one of the LEDs comprising a phosphor-free high energy UV LED. Light reflected to the spectrophotometer is divided into predetermined wavelength ranges through the utilization of a linear variable filter and photo detectors wherein the analog signal from a photo detector is converted to a digital value through the use of auto-ranging gain technique.

    Abstract translation: 分光光度计包括布置成圆形阵列的多个LED，每个LED具有通过使用脉冲宽度调制确定的每个具有由独特的荧光荧光粉涂层或透镜使用确定的唯一波长带的校准功率输入。 至少一个LED包括无磷高能UV LED。 通过使用线性可变滤波器和光电检测器将反射到分光光度计的光分成预定的波长范围，其中通过使用自动测距增益技术将来自光电检测器的模拟信号转换为数字值。

    APPARATUS FOR PHOTODYNAMIC THERAPY AND PHOTODETECTION
    287.
    发明申请
    APPARATUS FOR PHOTODYNAMIC THERAPY AND PHOTODETECTION 有权
    光电疗法和光电保护装置

    公开(公告)号：US20100145416A1

    公开(公告)日：2010-06-10

    申请号：US12473745

    申请日：2009-05-28

    Applicant: Uk KANG ,  Garri. V Papayan

    Inventor： Uk KANG ,  Garri. V Papayan

    IPC: A61N5/067 ,  A61N5/06

    CPC classification number: G01N21/6486 ,  A61B5/0059 ,  A61N5/0601 ,  A61N5/062 ,  G01J3/02 ,  G01J3/021 ,  G01J3/0248 ,  G01J3/10 ,  G01J3/12 ,  G01J3/36 ,  G01J3/4406 ,  G01N21/255 ,  G01N21/29 ,  G01N21/31 ,  G01N21/4738 ,  G01N21/6456 ,  G01N2201/0618

    Abstract: The present invention provides an apparatus for photodynamic therapy and fluorescence detection, in which a combined light source is provided to illuminate an object body and a multispectral fluorescence-reflectance image is provided to reproduce various and complex spectral images for an object tissue, thus performing effective photodynamic therapy for various diseases both outside and inside of the body.For this purpose, the present invention provides an apparatus for photodynamic therapy and photodetection, which provides illumination with light of various wavelengths and multispectral images, the apparatus including: an optical imaging system producing an image of an object tissue and transmitting the image to a naked eye or an imaging device; a combined light source including a plurality of coherent and non-coherent light sources and a light guide guiding incident light emitted from the light sources; a multispectral imaging system including at least one image sensor; and a computer system outputting an image of the object tissue to the outside. Thus, the apparatus for photodynamic therapy and photodetection of the present invention can effectively perform the photodynamic therapy and photodetection by means of the combined light source capable of irradiating light having various spectral components to an object tissue and the multispectral imaging system capable of obtaining images from several spectral portions for these various spectral ranges at the same time, thus improving the accuracy of diagnosis and efficiency of the photodynamic therapy.

    Abstract translation: 本发明提供了一种用于光动力学治疗和荧光检测的装置，其中提供组合光源以照射物体，并且提供多光谱荧光反射图像以再现对象组织的各种和复杂的光谱图像，从而执行有效 身体各种疾病的光动力治疗。 为此，本发明提供了一种用于光动力学治疗和光电检测的装置，其提供具有各种波长和多光谱图像的光的照明，所述装置包括：光学成像系统，其产生对象组织的图像并将图像发送到裸体 眼睛或成像装置; 包括多个相干和非相干光源的组合光源和引导从光源发射的入射光的光导; 包括至少一个图像传感器的多光谱成像系统; 以及将对象组织的图像输出到外部的计算机系统。 因此，本发明的光动力学治疗和光电检测装置可以通过能够将具有各种光谱成分的光照射到对象组织上的组合光源和能够获得图像的多光谱成像系统而有效地进行光动力学治疗和光电检测 同时对于这些不同光谱范围的几个光谱部分，从而提高光动力疗法的诊断准确性和效率。

    METHODS OF POLARIZATION ENGINEERING AND THEIR APPLICATIONS
    288.
    发明申请
    METHODS OF POLARIZATION ENGINEERING AND THEIR APPLICATIONS 有权
    极化工程方法及其应用

    公开(公告)号：US20100141939A1

    公开(公告)日：2010-06-10

    申请号：US12305731

    申请日：2007-06-21

    Applicant: Qiwen Zhan

    Inventor： Qiwen Zhan

    IPC: G01J3/44 ,  G01J3/28 ,  G01Q70/00 ,  G02B27/56

    CPC classification number: G01Q60/22 ,  G01J3/02 ,  G01J3/0224 ,  G01J3/10 ,  G01J3/44 ,  G01N21/658 ,  G01N2021/656 ,  G01Q30/02

    Abstract: Special polarization states are generated that have unique focusing properties that may be used to create extremely strong longitudinal fields. Combined with surface plasmon excitation, these polarization states can be used in apertureless near-field scanning optical microscopy systems. A radially polarized beam is directed into a plasmon-generating optical fiber comprising a metal coated, tapered, apertureless tip. The apertureless tip excites surface plasmon waves and direct the surface plasmon waves to the tip when a radially polarized beam propagates along the plasmon-generating optical fiber. An objective lens collects the near field optical signals from a sample positioned adjacent to the apertureless. Potential spatial resolution of the apertureless NSOM could reach beyond 10 nm. Such strong field enhancement allows the development of a reliable nano-Raman system that can measure mechanical as well as chemical compositions of samples with resolution beyond 10 nm.

    Abstract translation: 产生特殊的偏振状态，其具有独特的聚焦属性，可用于产生极强的纵向场。 结合表面等离子体激发，这些极化状态可用于无孔近场扫描光学显微镜系统。 将径向偏振光束引导到包括金属涂覆的锥形无孔尖端的等离子体发生光纤中。 当径向偏振光束沿着等离子体发生光纤传播时，无孔尖端激发表面等离子体波并将表面等离子体波引导到尖端。 物镜从邻近无孔的样品收集近场光信号。 无孔NSOM的潜在空间分辨率可以达到10nm以上。 这种强场增强可以开发可靠的纳米拉曼系统，可以测量分辨率超过10 nm的样品的机械以及化学成分。

    Portable Intelligent Fluorescence and Transmittance Imaging Spectroscopy System
    290.
    发明申请
    Portable Intelligent Fluorescence and Transmittance Imaging Spectroscopy System 失效
    便携式智能荧光和透射成像光谱系统

    公开(公告)号：US20100111369A1

    公开(公告)日：2010-05-06

    申请号：US12567931

    申请日：2009-09-28

    Applicant: Robert Lussier

    Inventor： Robert Lussier

    IPC: G06K9/62 ,  G01J1/58

    CPC classification number: G01J3/4406 ,  G01J3/02 ,  G01J3/0272 ,  G01J3/10 ,  G01J3/2823 ,  G01J3/42 ,  G01N21/31 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/6456 ,  G01N21/6486 ,  G01N2021/635 ,  G01N2021/8466

    Abstract: A portable fluorescence and transmittance imaging spectroscopy system for use in diagnosing plant health. The system has a primary LED light source array with spectral wavelengths in the 400-600 nm range, a focus cone that collects the LED light source output and focuses it, a controller that controls the primary LED array to turn it on and off, or certain of the spectral wavelengths on and off such that the primary LED array controllably emits light of a desired wavelength in the range, the light irradiating the plant through the focus cone, a digital imaging device that both spatially and temporally captures a fluorescence image comprising chlorophyll fluorescence emitted by the plant due to the emitted light from the LED array, a leaf holder located proximate to the output of the focus cone to maintain a consistent position and distance between the digital imaging device, the LED light source and the leaf and providing for fixed position and non-destructive leaf imaging and testing, a secondary light source for providing broad-band transmissive light through the leaf, a lens for focusing onto the imaging device the light emitted from the secondary light source, and one or more memory devices that store the fluorescence image and the transmitted light data received by the digital imaging device and store a library of plant fluorescence-intensity data indicative of both healthy plants and stressed or diseased plants, and plant light transmittance data indicative of certain plant conditions.

    Abstract translation: 便携式荧光和透射成像光谱系统，用于诊断植物健康。 该系统具有400-600nm范围内的光谱波长的主要LED光源阵列，聚焦锥体，用于收集LED光源输出并对其进行聚焦，该控制器控制主要LED阵列的打开和关闭，或 某些光谱波长开启和关闭，使得主LED阵列可控制地发射在该范围内的光，通过聚焦锥照射植物的光;数字成像装置，其在空间和时间上捕获包括叶绿素的荧光图像 由于来自LED阵列的发射光，植物发出的荧光，位于焦点锥体的输出附近的叶片保持器，以保持数字成像装置，LED光源和叶片之间的一致的位置和距离，并提供 固定位置和非破坏性叶成像和测试，用于通过叶片提供宽带透射光的二次光源，用于聚焦的透镜 将来自二次光源的光发射到成像装置上，以及存储由数字成像装置接收的荧光图像和透射光数据的一个或多个存储装置，并存储指示健康的植物荧光强度数据库 植物和受胁迫或患病植物，以及指示某些植物条件的植物光透射率数据。

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