公开(公告)号：US20160290867A1

公开(公告)日：2016-10-06

申请号：US15050368

申请日：2016-02-22

Applicant: Duke University

Inventor： Adam Wax ,  Robert N. Graf ,  Francisco E. Robles

IPC: G01J3/453 ,  G01B9/02

CPC classification number: G01J3/453 ,  G01B9/02044 ,  G01B9/02084 ,  G01B9/02087 ,  G01B9/02091 ,  G01J3/45 ,  G01J2003/4538 ,  G01N21/49

Abstract: Current apparatuses and methods for analysis of spectroscopic optical coherence tomography (SOCT) signals suffer from an inherent tradeoff between time (depth) and frequency (wavelength) resolution. In one non-limiting embodiment, multiple or dual window (DW) apparatuses and methods for reconstructing time-frequency distributions (TFDs) that applies two windows that independently determine the optical and temporal resolution is provided. For example, optical resolution is provided. For example, optical resolution may relate to scattering information about a sample, and temporal resolution may be related to absorption or depth related information. The effectiveness of the apparatuses and methods is demonstrated in simulations and in processing of measured OCT signals that contain fields which vary in time and frequency. The DW technique may yield TFDs that maintain high spectral and temporal resolution and are free from the artifacts and limitations commonly observed with other processing methods.

Abstract translation: 分光光学相干断层扫描（SOCT）信号的分析的现有装置和方法遭受时间（深度）和频率（波长）分辨率之间固有的折中。 在一个非限制性实施例中，提供了用于重建施加独立地确定光学和时间分辨率的两个窗口的时间频率分布（TFD）的多重或双窗口（DW）装置和方法。 例如，提供了光学分辨率。 例如，光学分辨率可以涉及关于样本的散射信息，并且时间分辨率可以与吸收或深度相关信息相关。 在模拟和处理包含在时间和频率上变化的场的测量的OCT信号中证明了装置和方法的有效性。 DW技术可以产生维持高光谱和时间分辨率的TFD，并且不存在通常用其它处理方法观察到的伪像和限制。

公开(公告)号：US09404801B2

公开(公告)日：2016-08-02

申请号：US14331193

申请日：2014-07-14

Applicant: Lawrence Livermore National Security, LLC

Inventor： Charles G. Stevens ,  Joseph W. Tringe ,  Christopher T. Cunningham

IPC: G01J5/02 ,  G01J3/453 ,  G01J3/433 ,  G01J3/10 ,  G01N21/35

CPC classification number: G01J3/453 ,  G01J3/10 ,  G01J3/4338 ,  G01N21/35

Abstract: In one embodiment, a heterodyne detection system for detecting light includes a first input aperture configured to receive first light from a scene input, a second input aperture configured to receive second light from a local oscillator input, a broadband local oscillator configured to provide the second light to the second input aperture, a dispersive element configured to disperse the first light and the second light, and a final condensing lens coupled to an infrared detector. The final condensing lens is configured to concentrate incident light from a primary condensing lens onto the infrared detector, and the infrared detector is a square-law detector capable of sensing the frequency difference between the first light and the second light. More systems and methods for detecting light are described according to other embodiments.

Abstract translation: 在一个实施例中，用于检测光的外差检测系统包括被配置为从场景输入接收第一光的第一输入孔，被配置为从本地振荡器输入接收第二光的第二输入孔，被配置为提供第二 被配置为分散第一光和第二光的分散元件以及耦合到红外检测器的最终聚光透镜。 最终聚光透镜被配置为将来自主聚光透镜的入射光集中到红外检测器上，并且红外检测器是能够感测第一光和第二光之间的频率差的平方律检测器。 根据其他实施例描述用于检测光的更多系统和方法。

公开(公告)号：US09354434B2

公开(公告)日：2016-05-31

申请号：US13546055

申请日：2012-07-11

Applicant: Shigeharu Kimura

Inventor： Shigeharu Kimura

IPC: G01B9/02 ,  G02B21/00 ,  G02B27/09 ,  G01N21/47 ,  G01J3/453 ,  G01J9/02 ,  G01J3/447

CPC classification number: G02B21/0072 ,  G01B9/02038 ,  G01J3/447 ,  G01J3/453 ,  G01J9/02 ,  G01N21/4795 ,  G02B21/0056 ,  G02B21/0068 ,  G02B27/0988

Abstract: Provided is an optical apparatus characterized in that alight from a light source is split to a first light and a second light, and the first light is focused onto an observation object, that an optical filter having a light shielding region for high resolution is disposed in at least one optical path selected from optical paths of the first light, second light and response light from the observation object, that an interference light formed by causing interference between the response light and the reference light in polarized states different from each other is split to multiple beams, and desired amplitude information signals are obtained from the multiple beams through a phase plate and a polarization plate to increase intensity of the second light, whereby the signal to noise ratio is improved.

Abstract translation: 本发明提供一种光学装置，其特征在于，从光源照射到第一光和第二光，第一光聚焦在观察对象上，具有高分辨率的遮光区域的滤光器配置在 选自来自观察对象的第一光，第二光和响应光的光路中的至少一个光路，将由响应光和参考光之间的干涉引起的偏振状态彼此不同的干涉光分裂为 通过相位板和偏振板从多个光束获得多个光束和期望的幅度信息信号，以增加第二光的强度，从而提高信噪比。

公开(公告)号：US20160131600A1

公开(公告)日：2016-05-12

申请号：US14898077

申请日：2014-06-12

Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION

Inventor： Brooks Hart PATE ,  Amanda STEBER ,  Brent HARRIS ,  Kevin K. LEHMANN

IPC: G01N22/00 ,  G01J3/453

CPC classification number: G01N22/00 ,  G01J3/453 ,  G01N21/3586

Abstract: Examples herein include apparatus and techniques that can be used to perform rotational spectroscopy on gas-phase samples. Such techniques can include using a spectrometer providing frequency synthesis and pulse modulation to provide excitation (e.g., pump or probe pulses) of a gas-phase sample at mm-wave frequencies. Synthesis of such mm-wave frequencies can include use of a frequency multiplier, such as an active multiplier chain (AMC). A free induction decay (FID) elicited by the excitation or other time-domain information can be obtained from the sample, such as down-converted and digitized. A frequency domain representation of the digitized information, such as a Fourier transformed representation, can be used to provide a rotational spectrum.

Abstract translation: 本文的实例包括可用于对气相样品进行旋转光谱的装置和技术。 这样的技术可以包括使用提供频率合成和脉冲调制的光谱仪以毫米波频率提供气相样品的激发（例如泵或探针脉冲）。 这种mm波频率的合成可以包括使用诸如有源乘法器链（AMC）的倍频器。 可以从样品获得由激发或其他时域信息引起的自由感应衰减（FID），如下变频和数字化。 诸如傅里叶变换表示之类的数字化信息的频域表示可用于提供旋转频谱。

公开(公告)号：US09335265B2

公开(公告)日：2016-05-10

申请号：US14175950

申请日：2014-02-07

Applicant: Agilent Technologies, Inc.

Inventor： William I. McAlexander

IPC: G01J3/42 ,  G01N21/61 ,  G01N21/39 ,  G01N21/59 ,  G01N21/41

CPC classification number: G01N21/59 ,  G01J3/42 ,  G01J3/453 ,  G01N21/39 ,  G01N21/41 ,  G01N21/61

Abstract: An apparatus and method for measuring the attenuation and dispersion introduced by a sample into an optical signal are disclosed. The apparatus includes a chirped light source, a beam splitter and an optical detector. The beam splitter splits the optical signal generated by the light source into a reference optical signal and a sample optical signal. The sample and reference optical signals are mixed on the detector after the sample optical signal has traversed an experimental sample thus generating a signal having an AC component related to an attenuation and a dispersion introduced by the experimental sample. The optical paths traversed by the reference and sample optical signals between the beam splitter and the detector are chosen such that the reference optical signal and the sample optical signal overlap in time but do not arrive at the optical detector at the same time.

Abstract translation: 公开了一种用于测量由样本引入到光信号中的衰减和色散的装置和方法。 该装置包括啁啾光源，分束器和光学检测器。 分束器将由光源产生的光信号分离成参考光信号和采样光信号。 在采样光信号已经穿过实验样本之后，采样和参考光信号被混合在检测器上，从而产生具有与由实验样品引入的衰减和色散相关的AC分量的信号。 选择光束分离器和检测器之间的基准光和采样光信号穿过的光路，使得参考光信号和采样光信号在时间上重叠，但不能同时到达光检测器。

公开(公告)号：US09239264B1

公开(公告)日：2016-01-19

申请号：US14490411

申请日：2014-09-18

Applicant: Joseph R. Demers

Inventor： Joseph R. Demers

IPC: G01N21/35 ,  G01J3/45 ,  G01J3/10

CPC classification number: G01J3/108 ,  G01J3/42 ,  G01J3/433 ,  G01J3/453 ,  H04B10/90

Abstract: Highly advantageous transceiver systems with common mode phase drift rejection and associated methods are disclosed which utilize certain phase modulators in configurations that reduce or eliminate inconsistent interference patterns caused by phase modulator phase drift.

Abstract translation: 公开了具有共模相位漂移抑制和相关方法的高度有利的收发器系统，其利用某些相位调制器在减少或消除由相位调制器相位漂移引起的不一致的干扰模式的配置中。

公开(公告)号：US20150286299A1

公开(公告)日：2015-10-08

申请号：US14246487

申请日：2014-04-07

Applicant: Thermo Scientific Portable Analytical Instruments Inc.

Inventor： Neil Bacon ,  Nathaneal Jeyachandran

IPC: G06F3/0354 ,  G06F3/041 ,  G01J3/453 ,  G01N23/223 ,  G01J3/44 ,  G01J3/443

CPC classification number: G06F3/03549 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0272 ,  G01J3/44 ,  G01J3/443 ,  G01J3/453 ,  G01N23/223 ,  G06F3/03545 ,  G06F3/0362 ,  G06F3/041

Abstract: A hand-held instrument includes a sample probe for evaluating at least one constituent of a sample; a processor configured with machine executable code stored on machine readable media for controlling the instrument; a display for providing output of the instrument; and, a pointing device for selecting output of the display and providing input to the processor, the pointing device configured for facilitating the selecting while holding the instrument. A method of use, a computer program product and embodiments of sample analyzers are disclosed.

Abstract translation: 手持式仪器包括用于评估样品的至少一种成分的样品探针; 配置有存储在用于控制所述仪器的机器可读介质上的机器可执行代码的处理器; 用于提供仪器输出的显示器; 以及用于选择所述显示器的输出并向所述处理器提供输入的指示设备，所述指示设备被配置为便于在保持所述仪器的同时进行所述选择。 公开了一种使用方法，计算机程序产品和样品分析仪的实施例。

公开(公告)号：US09019507B2

公开(公告)日：2015-04-28

申请号：US13735092

申请日：2013-01-07

Applicant: Hitachi, Ltd.

Inventor： Shigeharu Kimura ,  Masataka Shirai ,  Koichi Watanabe

IPC: G01J3/45 ,  G01J3/44 ,  G01J3/453

CPC classification number: G01J3/45 ,  G01J3/44 ,  G01J3/453

Abstract: A signal is amplified by making a CARS beam from an observed body and a reference beam which is a portion of a super continuum beam and has a frequency of ωAS=2ωP−ωST interfere with each other and taking out the signal from an interference beam of the CARS beam and the reference beam.

Abstract translation: 通过从观察体制作CARS光束，作为超连续光束的一部分且具有ωAS=2ωP-ωST的频率的参考光束相互干扰并从干涉光束中取出信号，来放大信号 CARS光束和参考光束。

公开(公告)号：US20150056690A1

公开(公告)日：2015-02-26

申请号：US14531659

申请日：2014-11-03

Applicant: Cambridge Research & Instrumentation, Inc.

Inventor： Richard Levenson ,  Paul J. Cronin ,  Kirk William Gossage ,  Clifford C. Hoyt

IPC: G01N33/483 ,  G01N21/64 ,  G01N21/25

CPC classification number: G01N33/4833 ,  A61B5/0059 ,  B82Y5/00 ,  B82Y10/00 ,  G01J3/32 ,  G01J3/4406 ,  G01J3/453 ,  G01N21/255 ,  G01N21/6486 ,  G01N2201/062 ,  G01N2201/125

Abstract: The invention features a method including: (i) providing spectrally resolved information about light coming from different spatial locations in a sample comprising deep tissue in response to an illumination of the sample, wherein the light includes contributions from different components in the sample; (ii) decomposing the spectrally resolved information for each of at least some of the different spatial locations into contributions from spectral estimates associated with at least some of the components in the sample; and (iii) constructing a deep tissue image of the sample based on the decomposition to preferentially show a selected one of the components.

公开(公告)号：US20150029575A1

公开(公告)日：2015-01-29

申请号：US14384550

申请日：2013-03-14

Applicant: Sumitomo Osaka Cement Co., Ltd.

Inventor： Tokutaka Hara ,  Youichi Hosokawa

IPC: H01S3/11 ,  H01S3/13 ,  G02F1/225 ,  H01S3/00

CPC classification number: H01S3/11 ,  G01J3/0205 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/26 ,  G01J3/2823 ,  G01J3/45 ,  G01J3/453 ,  G01J9/02 ,  G01J11/00 ,  G01J2009/0288 ,  G01N21/3581 ,  G02F1/01 ,  G02F1/21 ,  G02F1/2252 ,  G02F1/2255 ,  G02F1/2257 ,  G02F2001/212 ,  G02F2201/16 ,  G02F2203/13 ,  G02F2203/50 ,  G02F2203/56 ,  H01S3/0057 ,  H01S3/0085 ,  H01S3/06754 ,  H01S3/1301 ,  H01S5/12 ,  H01S2301/08

Abstract: Provided is an optical pulse-generator and an optical pulse-generating method which are capable of generating an optical pulse train with an arbitrary pattern. An optical pulse-generator 1 includes a first optical modulator 21 configured to modulate input light using a first modulation signal SIG1 to generate optical pulses, a second optical modulator 41 configured to perform a modulation operation using a second modulation signal SIG2 synchronizing with the first modulation signal SIG1 and having a signal pattern that is set to output only specific part of the optical pulses, and a dispersion compensator 30 configured to compensate a chirp of the optical pulse output from the first optical modulator 21.

Abstract translation: 提供了能够产生任意图案的光脉冲串的光脉冲发生器和光脉冲产生方法。 光脉冲发生器1包括第一光调制器21，其被配置为使用第一调制信号SIG1调制输入光以产生光脉冲;第二光调制器41，被配置为使用与第一调制同步的第二调制信号SIG2执行调制操作 信号SIG1，具有被设定为仅输出光脉冲的特定部分的信号图案;以及色散补偿器30，被配置为补偿从第一光调制器21输出的光脉冲的啁啾。