公开(公告)号：US20230228683A1

公开(公告)日：2023-07-20

申请号：US17870090

申请日：2022-07-21

Applicant: Cedars-Sinai Medical Center

Inventor： Pramod Butte ,  Paul Lapchak ,  David Scott Kittle

IPC: G01N21/64 ,  A61B5/00 ,  G01J3/28 ,  G01J3/44 ,  G01J3/02

CPC classification number: G01N21/6486 ,  G01N21/6402 ,  A61B5/0071 ,  G01J3/2889 ,  G01J3/4406 ,  G01N21/6428 ,  G01J3/0218 ,  G01N21/6408 ,  G01N21/64 ,  G01N21/645 ,  A61B5/0084 ,  A61B5/14556

Abstract: The invention provides systems for characterizing a biological sample by analyzing emission of fluorescent light from the biological sample upon excitation and methods for using the same. The system includes a laser source, collection fibers, a demultiplexer and an optical delay device. All references cited herein are incorporated by reference in their entirety as though fully set forth. Unless defined otherwise, technical and scientific terms used herein have the same meaning as commonly understood by one of-ordinary skill in the art in which this invention belongs.

公开(公告)号：US20230224446A1

公开(公告)日：2023-07-13

申请号：US18054801

申请日：2022-11-11

Applicant: ALIGN TECHNOLOGY, INC.

Inventor： Noam BABAYOFF

IPC: H04N13/15 ,  H04N13/257 ,  A61C9/00 ,  A61B1/06 ,  G01J3/02 ,  A61B1/00 ,  G01J3/10 ,  G01B11/24 ,  A61B5/00 ,  G01N21/25 ,  G01B11/25 ,  A61B1/247 ,  G06T7/90 ,  H01L27/148 ,  A61B1/24 ,  G01J3/50 ,  A61C19/04 ,  G06T7/00 ,  A61B5/107 ,  H04N13/296 ,  H04N13/207 ,  G06T7/12 ,  H04N13/271 ,  G01J3/51 ,  G01J3/46

CPC classification number: H04N13/15 ,  A61B1/00009 ,  A61B1/24 ,  A61B1/00096 ,  A61B1/247 ,  A61B1/0615 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/0676 ,  A61B1/0684 ,  A61B5/0068 ,  A61B5/0088 ,  A61B5/1077 ,  A61B5/1079 ,  A61C9/0053 ,  A61C9/0066 ,  A61C19/04 ,  G01B11/24 ,  G01B11/25 ,  G01J3/02 ,  G01J3/10 ,  G01J3/50 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/0224 ,  G01J3/0243 ,  G01J3/0256 ,  G01J3/501 ,  G01J3/508 ,  G01N21/255 ,  G06T7/0012 ,  G06T7/12 ,  G06T7/90 ,  H01L27/14868 ,  H04N13/207 ,  H04N13/257 ,  H04N13/271 ,  H04N13/296 ,  G01J3/51 ,  G01J3/462 ,  G06T2207/10024 ,  G06T2207/10028 ,  G06T2207/30036

Abstract: A device for determining the surface topology and associated color of a structure, such as a teeth segment, includes a scanner for providing depth data for points along a two-dimensional array substantially orthogonal to the depth direction, and an image acquisition means for providing color data for each of the points of the array, while the spatial disposition of the device with respect to the structure is maintained substantially unchanged. A processor combines the color data and depth data for each point in the array, thereby providing a three-dimensional color virtual model of the surface of the structure. A corresponding method for determining the surface topology and associate color of a structure is also provided.

公开(公告)号：US11698302B2

公开(公告)日：2023-07-11

申请号：US17188816

申请日：2021-03-01

Applicant: FiSens GmbH

Inventor： Christian Waltermann

IPC: G01J3/18 ,  G01D5/353 ,  G01J3/02 ,  G02B6/02 ,  G02B6/42

CPC classification number: G01J3/1895 ,  G01D5/35316 ,  G01J3/0218 ,  G02B6/02085 ,  G02B6/02147 ,  G02B6/4215

Abstract: The present invention relates to an apparatus for optical applications, a spectrometer system and method for producing an apparatus for optical applications, and in particular to an apparatus comprising an optical waveguide having a first refractive index along a light propagation axis interrupted by a plurality of scattering portions having a second refractive index. Each scattering portion has a long axis substantially perpendicular to the light propagation axis as well as a short axis substantially perpendicular to the light propagation axis and the long axis. A receiver unit or a transmitter unit is arranged on a side of the optical waveguide, the long axis being substantially perpendicular, i.e. normal to the plane of this side on which the receiver unit or transmitter unit is arranged. Accordingly, simplification and miniaturization of an optical apparatus can be realized.

公开(公告)号：US20190250035A1

公开(公告)日：2019-08-15

申请号：US16342884

申请日：2017-10-18

Applicant: ATOPTIX, Inc.

Inventor： Perry S. EDWARDS ,  Zhiwen LIU ,  Victor BUCKLEW ,  Baigang ZHANG

IPC: G01J3/02 ,  G01J3/42 ,  G01N21/64

CPC classification number: G01J3/0297 ,  G01J3/0218 ,  G01J3/0256 ,  G01J3/42 ,  G01N21/64

Abstract: A self-referencing mobile-compatible spectrophotometric system, including at least one light source, at least one spectral detection unit, and at least one reference sample. The system is configured to apply light from the at least one light source to a sample and receive a reflected light from the sample, and apply light to the at least one reference sample, and receive a reference reflected light from the at least one reference sample.

公开(公告)号：US20190200870A1

公开(公告)日：2019-07-04

申请号：US16240215

申请日：2019-01-04

Applicant: Deneb Medical, S.L.

Inventor： Noé Ortega-Quijano ,  Nebai Bernal Simón ,  Iñigo Olcoz Basarte ,  Juan Arregui Altuna ,  Aritz Lazkoz Del Campo ,  José Antonio Aguilera Andoaga ,  Carlos Aragón Garbizu

IPC: A61B5/00 ,  A61B90/00

CPC classification number: A61B5/0075 ,  A61B5/0084 ,  A61B34/00 ,  A61B90/04 ,  A61B2017/00061 ,  G01J3/0218 ,  G01J3/0248 ,  G01J3/44 ,  G01N21/718 ,  G01N2201/129 ,  G16C99/00

Abstract: The present invention relates to a device for the discrimination of biological tissues, such that it is capable of carrying out the discrimination of tissue under complicated operating conditions, for example due to the presence of contaminating elements given off by a cutting operation, due to the presence of moisture in the biological tissue, or due to the presence of a non-controlled atmosphere that interferes with the results of the readings. The invention allows building more complex devices, including cutting instruments, such that it is possible to carry out a surgical intervention in a safe manner by preventing cutting into tissues that are to be avoided during said cutting operation.

公开(公告)号：US20190170577A1

公开(公告)日：2019-06-06

申请号：US16271608

申请日：2019-02-08

Applicant: Otsuka Electronics Co., Ltd.

Inventor： Yoshihiro OSAWA ,  Tsutomu MIZUGUCHI ,  Munehiro NOGUCHI

IPC: G01J3/28 ,  G01J3/18 ,  G01N21/27 ,  G01J3/02 ,  G01N21/64 ,  G01N21/35 ,  G01N21/33

CPC classification number: G01J3/28 ,  G01J3/0218 ,  G01J3/0251 ,  G01J3/0254 ,  G01J3/0286 ,  G01J3/18 ,  G01N21/0332 ,  G01N21/274 ,  G01N21/33 ,  G01N21/35 ,  G01N21/645 ,  G01N2201/1211

Abstract: There is provided an optical characteristic measurement system that can be set up in a relatively short time and can increase a detection sensitivity. The optical characteristic measurement system includes a first measurement apparatus. The first measurement apparatus includes: a first detection element arranged in a housing; a first cooling unit at least partially joined to the first detection element that cools the detection element; and a suppression mechanism that suppresses temperature variations occurring around the detection element in the housing.

公开(公告)号：US20190069476A1

公开(公告)日：2019-03-07

申请号：US16106201

申请日：2018-08-21

Applicant: TOPCON CORPORATION

Inventor： Taichi YUASA

IPC: A01C21/00 ,  G01J3/02 ,  G01J3/10 ,  G01J3/427 ,  G01N21/3563

CPC classification number: A01C21/007 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0224 ,  G01J3/024 ,  G01J3/0272 ,  G01J3/0286 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/108 ,  G01J3/427 ,  G01J2003/104 ,  G01J2003/4275 ,  G01N21/3563 ,  G01N21/359 ,  G01N2021/1797 ,  G01N2021/3181 ,  G01N2021/8466 ,  G01N2201/0214 ,  G01N2201/0221 ,  G01N2201/0627 ,  G01N2201/0691

Abstract: A light source section configured to couple a plurality of laser beams having different wavelengths and emit measuring light; an illuminating section configured to illuminate a measurement target at a predetermined angle; a light receiving section configured to receive reflected measuring light from the measurement target; and a controlling section configured to compute a reflectance at each of the wavelengths, based on a light receiving result. The light source section includes: a first and a second light source configured to emit each laser beams having different wavelengths; and a dichroic mirror disposed in optical axes of the laser beams intersected, configured to combine the laser beams. The light receiving section includes: a first, a second and a third light receiving unit configured to receive the reflected measuring light from different distance. The controlling section is configured to select which of results from each light receiving unit to use.

公开(公告)号：US20190033287A1

公开(公告)日：2019-01-31

申请号：US16134245

申请日：2018-09-18

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01N33/49 ,  G01J3/02 ,  G01N21/25 ,  G01N21/03 ,  G01J3/42 ,  G01N21/31 ,  G01N21/27

CPC classification number: G01N21/0303 ,  G01J3/0202 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/0297 ,  G01J3/10 ,  G01J3/14 ,  G01J3/28 ,  G01J3/42 ,  G01J2003/2866 ,  G01N21/255 ,  G01N21/274 ,  G01N21/31 ,  G01N33/49 ,  G01N33/492 ,  G01N2021/0321 ,  G01N2021/0389 ,  G01N2201/062 ,  G01N2201/0633 ,  G01N2201/0634 ,  G01N2201/0638

Abstract: A replaceable cuvette assembly for use in an optical absorbance measurement system for measuring whole-blood hemoglobin parameters or whole-blood bilirubin parameters. The replaceable cuvette assembly includes a cuvette substrate and a cuvette module fixedly connected to the cuvette substrate wherein the cuvette substrate is a support for securing the cuvette assembly within the optical absorbance measurement system. The cuvette module has a sample inlet port, a sample outlet port, an electronic chip assembly, a sample receiving chamber that fluidly communicates with the sample inlet port and the sample outlet port, a first cuvette window, and a second cuvette window forming a portion of the sample receiving chamber. The first cuvette window and the second cuvette window are aligned with each other defining a cuvette optical path length between the first cuvette window and the second cuvette window and disposed within an optical path of the optical absorbance measurement system.

公开(公告)号：US20190017992A1

公开(公告)日：2019-01-17

申请号：US16132689

申请日：2018-09-17

Applicant: Nova Biomedical Corporation

Inventor： Michael S. Cafferty ,  Scott P. Cionek

IPC: G01N33/49 ,  G01J3/02 ,  G01N21/25 ,  G01N21/03 ,  G01J3/42 ,  G01N21/31 ,  G01N21/27

CPC classification number: G01N21/0303 ,  G01J3/0202 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/0297 ,  G01J3/10 ,  G01J3/14 ,  G01J3/28 ,  G01J3/42 ,  G01J2003/2866 ,  G01N21/255 ,  G01N21/274 ,  G01N21/31 ,  G01N33/49 ,  G01N33/492 ,  G01N2021/0321 ,  G01N2021/0389 ,  G01N2201/062 ,  G01N2201/0633 ,  G01N2201/0634 ,  G01N2201/0638

Abstract: A calibrating-light module for use in a system for measuring whole-blood hemoglobin parameters or whole-blood bilirubin parameters. The calibrating-light module includes a calibrating module housing, a light beam receiving portion connected to a first end of the calibrating module housing, a calibrating light portion connected to a side of the calibrating module housing wherein the side is transverse to the first end, and an optic fiber portion connected to a second end of the calibrating module housing wherein the calibrating module housing, the light beam receiving portion and the optic fiber portion are aligned with an optical path and the calibrating light portion is spaced from and transverse to the optical path.

公开(公告)号：US20180340797A1

公开(公告)日：2018-11-29

申请号：US16053088

申请日：2018-08-02

Applicant: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS

Inventor： Samir MEKID

IPC: G01D5/26 ,  G01D5/353 ,  G01J3/02

CPC classification number: G01D5/268 ,  G01D5/35316 ,  G01J3/0218

Abstract: The system with branched optical fibers provides diagnostics and measurement of static and/or dynamic parameters in structures and structural elements. The system includes a structural material or element having a branched optical fiber embedded therein. The branched optical fiber includes a primary optical fiber segment and at least one secondary optical fiber segment branching therefrom. One or more fiber Bragg grating sensors are arranged on, and are in optical communication with, the primary optical fiber segment and the at least one secondary optical fiber segment. A signal analyzer receives signals generated by the fiber Bragg grating sensors representative of a magnitude of the physical parameter of the structural element.