公开(公告)号：US20240044776A1

公开(公告)日：2024-02-08

申请号：US18072655

申请日：2022-11-30

Applicant: AUO Corporation

Inventor： Shu-Jiang Liu ,  Chun-Cheng Hung ,  Wen-Jen Li ,  Zhi-Jain Yu ,  Han-Chung Lai

IPC: G01N21/03 ,  B01L3/00 ,  G02B6/43

CPC classification number: G01N21/0303 ,  B01L3/502715 ,  G02B6/43 ,  G01N2201/0873 ,  G01N2201/0668

Abstract: Disclosed is a microfluidic detection device including a circuit substrate and a transparent substrate. The circuit substrate is provided with at least one first light-emitting device used to emit a detection beam, a photodetector used to receive the detection beam and send out a sensing signal, and a control circuit electrically connected to the first light-emitting device and the photodetector. The transparent substrate overlaps the circuit substrate and is provided with a microfluidic channel and a light guide structure. The light guide structure has a light incident surface disposed corresponding to the first light-emitting device and a light exiting surface disposed corresponding to the photodetector. The light guide structure extends from each of the light incident surface and the light exiting surface to the microfluidic channel and is adapted to transmit the detection beam into and out of the microfluidic channel.

公开(公告)号：US09952139B2

公开(公告)日：2018-04-24

申请号：US15262171

申请日：2016-09-12

Applicant: THERMO ELECTRON SCIENTIFIC INSTRUMENTS LLC

Inventor： Damian W. Ashmead ,  James V. Howard ,  Kevin K. Kim ,  Andrew Martin Braasch

IPC: G01N21/01 ,  G01N21/03 ,  G01N21/27 ,  G01R33/07 ,  G01R33/09 ,  G01N21/31 ,  G01D5/14

CPC classification number: G01N21/0303 ,  G01D5/145 ,  G01N21/27 ,  G01N21/31 ,  G01N2021/035 ,  G01N2021/036 ,  G01N2201/0668 ,  G01N2201/08 ,  G01R33/07 ,  G01R33/093

Abstract: An apparatus includes a first pedestal surface coupled to i) a swing arm and to ii) a light source. The apparatus further includes a magnet, a base plate, a mechanical stop coupled to the base plate, and a second pedestal surface mechanically coupled to said base plate and configured to receive a liquid sample, said second pedestal surface being coupled to a spectrometer. The apparatus further includes a magnetic flux sensor located between north and south magnetic flux fields of the magnet such that the magnetic flux reaching the sensor while the mechanical stop is in physical contact with the swing arm provides a linear range of output of the magnetic flux sensor, and a processor adapted to calibrate the point for minimum optical path length using a threshold magnetic flux field emitted from the magnet and detected by the magnetic flux sensor.

公开(公告)号：US20180052099A1

公开(公告)日：2018-02-22

申请号：US15387180

申请日：2016-12-21

Applicant: KLA-Tencor Corporation

Inventor： Andrew V. Hill ,  Amnon Manassen ,  Ohad Bachar

IPC: G01N21/25 ,  G01J3/12 ,  G01J3/10

CPC classification number: G01N21/255 ,  G01J1/0418 ,  G01J1/4257 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/06 ,  G01J3/10 ,  G01J3/12 ,  G01J2001/4247 ,  G01J2003/069 ,  G01J2003/1213 ,  G01J2003/1217 ,  G01J2003/1221 ,  G01J2003/1234 ,  G01N2201/0666 ,  G01N2201/0668 ,  G01N2201/0675 ,  G01N2201/0683 ,  G03F7/70633

Abstract: A metrology system includes an illumination source to generate an illumination beam, a multi-channel spectral filter, a focusing element to direct illumination from the single optical column to a sample, and at least one detector to capture the illumination collected from the sample. The multi-channel spectral filter includes two or more filtering channels having two or more channel beam paths. The two or more filtering channels filter illumination propagating along the two or more channel beam paths based on two or more spectral transmissivity distributions. The multi-channel spectral filter further includes a channel selector to direct at least a portion of the illumination beam into at least one selected filtering channel to filter the illumination beam. The multi-channel spectral filter further includes at least one beam combiner to combine illumination from the two or more filtering channels to a single optical column.

公开(公告)号：US20180011007A1

公开(公告)日：2018-01-11

申请号：US15638987

申请日：2017-06-30

Applicant: bluepoint medical GmbH & Co. KG

Inventor： Bernd LINDNER

IPC: G01N21/17 ,  G01N21/25 ,  G01N21/01 ,  G01N21/45

CPC classification number: G01N21/1717 ,  G01J3/0205 ,  G01J3/0216 ,  G01J3/10 ,  G01J3/42 ,  G01J2003/102 ,  G01N21/256 ,  G01N21/314 ,  G01N33/0037 ,  G01N33/0042 ,  G01N2021/0106 ,  G01N2021/1704 ,  G01N2021/1736 ,  G01N2021/1742 ,  G01N2021/1748 ,  G01N2021/3155 ,  G01N2021/3181 ,  G01N2021/451 ,  G01N2201/0627 ,  G01N2201/0631 ,  G01N2201/0668 ,  G01N2201/0806 ,  G01N2201/1211 ,  G01N2201/1218 ,  G02B6/00 ,  G02B6/0068 ,  Y02A50/245

Abstract: An arrangement for measuring gas concentrations in a gas absorption method, wherein the arrangement includes a plurality of light sources, a measuring cell, at least one measuring receiver and an evaluation apparatus. The measuring cell has a narrow, longitudinally-extended beam path with an entrance-side opening diameter B and an absorption length L with L>B, wherein the measuring cell has a gas inlet and a gas outlet wherein a plurality of light sources of different wavelength spectra is grouped into a first light source group wherein an optical homogeniser is interposed between the first light source group and the measuring cell, wherein, in particular, the homogeniser is coupled to the light source group directly or via a common optical assembly.

公开(公告)号：US20170307513A1

公开(公告)日：2017-10-26

申请号：US15134528

申请日：2016-04-21

Applicant: Instrumentation Laboratory Company

Inventor： Brian Joseph Bosy ,  Josef Kerimo

IPC: G01N21/05 ,  G01N21/27 ,  G01N21/03 ,  G01N33/49

CPC classification number: G01N21/05 ,  B01L3/508 ,  B01L2200/0689 ,  B01L2300/0822 ,  G01N21/03 ,  G01N21/0303 ,  G01N21/27 ,  G01N33/4915 ,  G01N2021/058 ,  G01N2021/115 ,  G01N2201/061 ,  G01N2201/062 ,  G01N2201/0668

Abstract: A sample cell apparatus for use in spectroscopic determination of an analyte in a body fluid sample includes a first plate member made from an optically clear material and a second plate member made from an optically clear material and opposing the first plate member. A channel extending into a surface of the first plate member and an opposing surface of the second plate member houses a floating seal. The floating seal surrounds a fluid chamber that retains a sample of body fluid for optical measurement. The fluid chamber may be opened for flushing by separating the first plate member from the second plate member. During measurements the fluid chamber is closed to define a repeatable optical path-length therethrough by urging the first plate member against the second plate member without compressing the floating seal between the first plate member and the second plate member.

公开(公告)号：US20170292918A1

公开(公告)日：2017-10-12

申请号：US15626123

申请日：2017-06-18

Applicant: KLA-Tencor Corporation

Inventor： Pavel Kolchin ,  Mikhail Haurylau ,  Junwei Wei ,  Dan Kapp ,  Robert Danen ,  Grace Chen

IPC: G01N21/95 ,  G01N21/47 ,  G01N21/88 ,  G01N21/956

CPC classification number: G01N21/9501 ,  G01N21/47 ,  G01N21/8806 ,  G01N21/8851 ,  G01N21/956 ,  G01N21/95623 ,  G01N2021/8887 ,  G01N2201/0668

Abstract: Methods and systems for determining a configuration for an optical element positioned in a collection aperture during wafer inspection are provided. One system includes a detector configured to detect light from a wafer that passes through an optical element, which includes a set of collection apertures, when the optical element has different configurations thereby generating different images for the different configurations. The system also includes a computer subsystem configured for constructing additional image(s) from two or more of the different images, and the two or more different images used to generate any one of the additional image(s) do not include only different images generated for single collection apertures in the set. The computer subsystem is further configured for selecting one of the different or additional configurations for the optical element based on the different images and the additional image(s).

公开(公告)号：US09709510B2

公开(公告)日：2017-07-18

申请号：US14749564

申请日：2015-06-24

Applicant: KLA-Tencor Corporation

Inventor： Pavel Kolchin ,  Mikhail Haurylau ,  Junwei Wei ,  Dan Kapp ,  Robert Danen ,  Grace Chen

IPC: G01N21/00 ,  G01N21/95 ,  G01N21/956 ,  G01N21/88

CPC classification number: G01N21/9501 ,  G01N21/47 ,  G01N21/8806 ,  G01N21/8851 ,  G01N21/956 ,  G01N21/95623 ,  G01N2021/8887 ,  G01N2201/0668

Abstract: Methods and systems for determining a configuration for an optical element positioned in a collection aperture during wafer inspection are provided. One system includes a detector configured to detect light from a wafer that passes through an optical element, which includes a set of collection apertures, when the optical element has different configurations thereby generating different images for the different configurations. The system also includes a computer subsystem configured for constructing additional image(s) from two or more of the different images, and the two or more different images used to generate any one of the additional image(s) do not include only different images generated for single collection apertures in the set. The computer subsystem is further configured for selecting one of the different or additional configurations for the optical element based on the different images and the additional image(s).

公开(公告)号：US20170082533A1

公开(公告)日：2017-03-23

申请号：US15262171

申请日：2016-09-12

Applicant: THERMO ELECTRON SCIENTIFIC INSTRUMENTS LLC

Inventor： Damian W. ASHMEAD ,  James V. HOWARD ,  Kevin K. KIM ,  Andrew Martin BRAASCH

IPC: G01N21/03 ,  G01R33/09 ,  G01N21/27 ,  G01R33/07

CPC classification number: G01N21/0303 ,  G01D5/145 ,  G01N21/27 ,  G01N21/31 ,  G01N2021/035 ,  G01N2021/036 ,  G01N2201/0668 ,  G01N2201/08 ,  G01R33/07 ,  G01R33/093

Abstract: An apparatus includes a first pedestal surface coupled to i) a swing arm and to ii) a light source. The apparatus further includes a magnet, a base plate, a mechanical stop coupled to the base plate, and a second pedestal surface mechanically coupled to said base plate and configured to receive a liquid sample, said second pedestal surface being coupled to a spectrometer. The apparatus further includes a magnetic flux sensor located between north and south magnetic flux fields of the magnet such that the magnetic flux reaching the sensor while the mechanical stop is in physical contact with the swing arm provides a linear range of output of the magnetic flux sensor, and a processor adapted to calibrate the point for minimum optical path length using a threshold magnetic flux field emitted from the magnet and detected by the magnetic flux sensor.

公开(公告)号：US20170074791A1

公开(公告)日：2017-03-16

申请号：US14895305

申请日：2015-06-01

Applicant: ATAGO CO., LTD.

Inventor： Hideyuki AMAMIYA ,  Masanosuke TANAKA

IPC: G01N21/41 ,  G01N21/21 ,  G01J4/04 ,  G01N33/02

CPC classification number: G01N21/4133 ,  G01J4/04 ,  G01N21/03 ,  G01N21/21 ,  G01N21/43 ,  G01N33/02 ,  G01N2021/1734 ,  G01N2201/0668 ,  G01N2201/068

Abstract: A device includes a sample chamber (1) configured to receive the object, a polarization degree measuring member (2) configured to measure the polarization degree of the object received in the sample chamber (1), and a refractive index measuring member (3) configured to measure information corresponding to the refractive index of the object received in the sample chamber (1). The polarization degree measuring member (2) includes a polarization modulation member (11) configured to perform polarization modulation on a light beam (9) for analyzing the object and allow the modulated light beam to enter the sample chamber (1), an intensity detection member (12) configured to detect an intensity of the light beam (5) exiting from the sample chamber, and a polarization degree calculation member (13). The refractive index measuring member (3) includes a position detection member (26) and a refractive index (concentration) calculation member (13).

Abstract translation: 一种装置，包括被配置为接收物体的样品室（1），被配置为测量在样品室（1）中接收的物体的偏振度的偏振度测量构件（2）和折射率测量构件（3） 被配置为测量与在样本室（1）中接收的物体的折射率相对应的信息。 偏振度测量部件（2）包括偏振调制部件（11），被配置为对用于分析物体的光束（9）进行偏振调制，并允许调制光束进入样品室（1），强度检测 被配置为检测从所述样品室出射的光束（5）的强度的构件（12），以及偏振度计算构件（13）。 折射率测量构件（3）包括位置检测构件（26）和折射率（浓度）计算构件（13）。

公开(公告)号：US20160158427A1

公开(公告)日：2016-06-09

申请号：US15015394

申请日：2016-02-04

Applicant: FRESENIUS MEDICAL CARE HOLDINGS, INC.

Inventor： Louis L. Barrett ,  Perry N. Law

IPC: A61M1/14 ,  G01N33/49 ,  G01N21/59

CPC classification number: A61M1/14 ,  A61B5/14535 ,  A61B5/14557 ,  A61M1/3609 ,  A61M1/3621 ,  A61M1/367 ,  A61M2202/0413 ,  A61M2205/3306 ,  A61M2205/3313 ,  A61M2205/50 ,  A61M2205/70 ,  A61M2205/702 ,  A61M2230/20 ,  A61M2230/205 ,  A61M2230/207 ,  G01N21/0303 ,  G01N21/05 ,  G01N21/59 ,  G01N33/4925 ,  G01N33/721 ,  G01N2201/062 ,  G01N2201/0668

Abstract: An optical blood monitoring system and corresponding method avoid the need to obtain a precise intensity value of the light impinging upon the measured blood layer during the analysis. The system is operated to determine at least two optical measurements through blood layers of different thickness but otherwise substantially identical systems. Due to the equivalence of the systems, the two measurements can be compared so that the bulk extinction coefficient of the blood can be calculated based only on the known blood layer thicknesses and the two measurements. Reliable measurements of various blood parameters can thereby be determined without certain calibration steps.