Abstract:
This invention concerns spectroscopy apparatus comprising a light source arranged to generate a light profile on a sample, a photodetector having at least one photodetector element for detecting characteristic light generated from interaction of the sample with light from the light source, a support for supporting the sample, the support movable relative to the light profile, and a processing unit. The processing unit is arranged to associate a spectral value recorded by the photodetector element at a particular time with a point on the sample predicted to have generated the characteristic light recorded by the photodetector element at the particular time based on relative motion anticipated to have occurred between the support and the light profile.
Abstract:
The present invention generally pertains to a system, method and kit for the detection and measurement of spectroscopic properties of light from a sample, or the scalable detection and measurement of spectroscopic properties of light from each sample present among multiple samples, simultaneously, wherein the system comprises: an optical train comprising a dispersing element; and an image sensor. The light detected and measured may comprise light scattered from a sample, emitted as chemiluminescence by a chemical process within a sample, selectively absorbed by a sample, or emitted as fluorescence from a sample following excitation.
Abstract:
Snapshot spectral imagers comprise an imaging lens, a dispersed image sensor and a restricted isometry property (RIP) diffuser inserted in the optical path between the source image and the image sensor. The imagers are used to obtain a plurality of spectral images of the source object in different spectral bands in a single shot. In some embodiments, the RIP diffuser is one dimensional. An optional disperser may be added in the optical path, to provide further dispersion at the image sensor. In some embodiments, all imager components except the RIP diffuser may be part of a digital camera, with the RIP diffuser added externally. In some embodiments, the RIP diffuser may be included internally in a digital camera.
Abstract:
Snapshot spectral imagers comprise an imaging lens, a dispersed image sensor and a restricted isometry property (RIP) diffuser inserted in the optical path between the source image and the image sensor. The imagers are used to obtain a plurality of spectral images of the source object in different spectral bands in a single shot. In some embodiments, the RIP diffuser is one dimensional. An optional disperser may be added in the optical path, to provide further dispersion at the image sensor. In some embodiments, all imager components except the RIP diffuser may be part of a digital camera, with the RIP diffuser added externally. In some embodiments, the RIP diffuser may be included internally in a digital camera.
Abstract:
A portable hyperspectral imager. The imager is modular and may include a hyperspectral camera and a removably-coupled mobile display module. The hyperspectral camera may include an Offner spectrometer. The mobile display module may be adapted to receive data from the hyperspectral camera and may include an internal camera. The mobile display module may include a cell phone or a tablet computer. The mobile display module may be integrally attached to the hyperspectral camera. The integral attachment may include a data link or USB connection. The length of the data link or USB connection may be less than 6 inches and the imager may weigh less than one pound. The imager may include a battery module or a scanning optical module.
Abstract:
A first location comprising an unknown material may be scanned using SWIR hyperspectral imaging in a dual polarization configuration. Surveying may also be applied to thereby determine whether or not a human is present. This surveying may be achieved my assessing LWIR data, data acquired from motion sensors, and combinations thereof. If no human is present, a second location may be interrogated using Raman spectroscopic techniques to thereby obtain a Raman data set representative of the region of interest. This Raman data set may be assessed to associate an unknown material with a known material. This assessment may be achieved by comparing the Raman data set to one or more reference data sets in a reference database, where each reference data set is associated with a known material.
Abstract:
The present invention generally pertains to a system, method and kit for the detection and measurement of spectroscopic properties of light from a sample, or the scalable detection and measurement of spectroscopic properties of light from each sample present among multiple samples, simultaneously, wherein the system comprises: an optical train comprising a dispersing element; and an image sensor. The light detected and measured may comprise light scattered from a sample, emitted as chemiluminescence by a chemical process within a sample, selectively absorbed by a sample, or emitted as fluorescence from a sample following excitation.
Abstract:
The disclosure is related systems and method for improved accuracy and precision in Raman spectroscopy. In one embodiment, a device may comprise a Raman spectroscopic apparatus configured to determine a property of a sample by directing photons at the sample and measuring a resulting Raman scattering, a positioning apparatus capable of manipulating a position of the sample, and the device being configured to selectively adjust a focus of the Raman spectroscopic apparatus to adjust an intensity of the Raman scattering. Another embodiment may be a method comprising performing a depth focus Raman spectra screening on a sample to determine a depth focus with a maximum-intensity Raman spectra, wherein the depth focus spectra screening comprises performing Raman spectra scans on the sample at a plurality of depth foci, and modifying a process based on a result of the Raman spectra scan at the depth focus with the maximum-intensity Raman spectra.
Abstract:
A spectrophotometer including a light tube having a spectrophotometer head mounted to one end of the light tube and a diffraction grating head mounted to the opposite end. The spectrophotometer head having a bore therethrough for receiving incoming light from a light source providing a light path through the spectrophotometer head and light tube; Further, a slit is disposed in the light path and a vial of colored liquid is suspended halfway through the light path. The diffraction grating includes a bore aligned with the light path and includes a focusing lens and a diffraction grating disposed in the light path. The diffraction grating displaying a spectrum with an upper half displaying the spectrum of the light transmitted through the colored liquid and the lower half displaying the spectrum of the light source.
Abstract:
The present disclosure provides for a system and method for assessing chronic exposure of a biological sample, such as a bodily fluid, to an analyte of interest. A biological sample may be illuminated to thereby generate a one or more pluralities of interacted photons. These interacted photons may be detected to thereby generate one or more spectroscopic data sets representative of a biological sample. Spectroscopic data sets generated may be compared to at least one reference data set. Each reference data set may be associated with a known exposure to a known analyte. The present disclosure contemplates that the system and method disclosed herein may be used to analyze exposure of biological samples to at least one analyte over time. Data sets may be obtained at various time intervals to assess changes in a molecular composition as a result of chronic exposure to an analyte.