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公开(公告)号：KR1020150035216A
公开(公告)日：2015-04-06
申请号：KR1020130115508
申请日：2013-09-27
Applicant: 한국식품연구원
IPC: A61K36/185 , A61K36/36 , A61P3/04
Abstract: 본발명은시금치추출물, 특히시금치당지질분획을유효성분으로함유하는비만, 또는비만으로인한대사성질환의예방또는치료용약학조성물에관한것이다. 또한, 본발명은시금치추출물, 특히시금치당지질분획을유효성분으로함유하는비만, 또는비만으로인한대사성질환의예방또는개선용건강기능식품에관한것이다. 본발명의시금치당지질분획은지질소화를억제하여항비만용도또는체중조절용도에적용될수 있다.
Abstract translation: 本发明涉及含有菠菜提取物，特别是菠菜糖脂部分作为预防或治疗由肥胖引起的肥胖或代谢性疾病的活性成分的药物组合物。 此外，本发明涉及含有菠菜提取物，特别是菠菜糖脂部分作为预防或减轻由肥胖引起的肥胖症或代谢性疾病的活性成分的保健食品。 本发明的菠菜糖脂部分抑制脂质消化，因此可以用于抗肥胖目的或体重控制目的。
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公开(公告)号：KR1020140061078A
公开(公告)日：2014-05-21
申请号：KR1020120128239
申请日：2012-11-13
Applicant: 한국식품연구원
IPC: C08B37/00 , A61K36/07 , A61K31/716
CPC classification number: A61K31/716 , A61K36/07 , A61K2236/15 , C08B37/0003 , C08B37/0024
Abstract: The present invention relates to a method for preparing β-glucan from mushrooms. The present invention can obtain β-glucan in a high yield through a series of steps of the preparation of mushroom microparticles through first crude grinding and second fine grinding processes, and ultrasonic extraction and heat extraction thereof, and is thus economical. In addition, alkaline neutralization which is a problem of a conventional alkaline treatment extraction, and environmental pollution caused thereby can be solved. Therefore, the present invention can be useful for preparing β-glucan, and the prepared β-glucan can be useful for preparing medical supplies, cosmetics, dietary supplements, and food.
Abstract translation: 本发明涉及从蘑菇制备β-葡聚糖的方法。 本发明通过首先进行粗磨和第二精细研磨，通过超声提取和热提取，通过一系列制备蘑菇微粒的步骤，可以高收率地获得β-葡聚糖，因此是经济的。 此外，可以解决作为常规碱处理提取的问题的碱中和以及由此引起的环境污染。 因此，本发明可用于制备β-葡聚糖，所制备的β-葡聚糖可用于制备医疗用品，化妆品，膳食补充剂和食品。
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公开(公告)号：KR101360836B1
公开(公告)日：2014-02-12
申请号：KR1020130025687
申请日：2013-03-11
Applicant: 한국식품연구원
CPC classification number: A23L9/10 , A23B7/08 , A23L29/20 , A23L33/105
Abstract: The present invention relates to a method for making a mulberry pudding containing mulberry with an original form and a mulberry pudding made thereby. The method according to the present invention comprises the steps of: (a) mixing mulberry and white sugar, heating the mixture in a double boiler at 70-90°C, and sugaring the mixture in a sterilized bottle for 10 to 20 days; (b) immersing the sugared mulberry in an alginate solution to coat the mulberry; (c) immersing and then drying the coated mulberry in calcium chloride to prepare mulberry with an original form; (d) preparing a pudding liquid containing a mulberry extract, plate gelatin, a fruit concentrate, hydrous crystalline glucose, sugar, additives; and (e) placing the pudding liquid in a container, and adding mulberry with an original form, followed by gelation. The mulberry pudding made by the method has excellent flavor and taste and can be longer stored as compared with the existing puddings.
Abstract translation: 本发明涉及一种制备含有原始形式的桑树和由此制成的桑丁布丁的桑丁布丁的方法。 根据本发明的方法包括以下步骤：（a）将桑树和白糖混合，在70-90℃的双层锅炉中加热混合物，并将混合物在无菌瓶中加糖10至20天; （b）将含糖桑桑浸入藻酸盐溶液中以覆盖桑树; （c）将涂覆的桑树浸入氯化钙中，然后干燥以制备原始形式的桑树; （d）制备含有桑叶提取物，板状明胶，果实浓缩物，含水结晶葡萄糖，糖，添加剂的布丁液; 和（e）将布丁液放入容器中，并加入原始形式的桑树，然后凝胶化。 通过该方法制成的桑丁布丁具有优异的风味和味道，与现有的布丁相比可以更长时间地储存。
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公开(公告)号：KR101317320B1
公开(公告)日：2013-10-11
申请号：KR1020110078568
申请日：2011-08-08
Applicant: 한국식품연구원
IPC: A61K36/282 , A61P25/28 , A61P25/00
Abstract: 본 발명은 청호 추출물을 유효성분으로 포함하는 기억력 및 학습 능력 증진용 조성물 및 인지기능장애 예방 및 치료용 조성물에 관한 것이다. 본 발명은 아세틸콜린스테라아제의 활성을 억제, 항산화 활성(예컨대, 활성산소종) 및 NMDA 리셉터와의 친화력을 통하여 신경세포, 특히 대뇌 기저부의 신경세포의 손상을 억제시킬 수 있는 효과를 가진다. 본 발명은 신경세포를 보호 및 손상의 예방 효과를 통하여 기억력 및 학습 능력을 증진시킬 수 있을 뿐 만 아니라 인지기능장애로 질환을 예방 및 치료 할 수 있는 효능을 발휘한다. 또한, 본 발명은 기억력 및 학습 능력의 증진 효능, 또는 인지기능장애를 예방 및 치료 효능을 가지는 청호 추출물의 의약 및 식품으로서의 기초적인 자료를 제공한다.
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Patent Agency Ranking
公开(公告)号：KR1020120114077A
公开(公告)日：2012-10-16
申请号：KR1020110031834
申请日：2011-04-06
Applicant: 한국식품연구원
IPC: A61K31/198 , A61K36/8962 , A61P35/00
Abstract: PURPOSE: A method for maintaining antioxidation function of garlic extract is provided to maintain storage stability and to maintain antioxidation function of allinase. CONSTITUTION: A method for maintaining antioxidation function comprises a step of homogenizing allinase, surfactant, and oil. The surfactant is propylene glycol monostearate or polyglycerol polyricinoleate. Allinase is extracted from garlic. A composition with maintained antioxidation function contains surfactant and oil-coated allinase.
Abstract translation: 目的：提供维持大蒜提取物抗氧化功能的方法，保持贮藏稳定性，维持蒜素的抗氧化功能。 构成：维持抗氧化功能的方法包括使蒜素，表面活性剂和油匀浆的步骤。 表面活性剂是丙二醇单硬脂酸酯或聚甘油多蓖麻油酸酯。 蒜素从大蒜中提取。 具有维持抗氧化功能的组合物含有表面活性剂和油包衣的allinase。
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公开(公告)号：KR1020120029992A
公开(公告)日：2012-03-27
申请号：KR1020110078568
申请日：2011-08-08
Applicant: 한국식품연구원
IPC: A61K36/282 , A61P25/28 , A61P25/00
Abstract: PURPOSE: A composition for improving memory power and learning ability comprising extract from artemisia apiaceae as active ingredient is provided to control antioxidant activity and activity of acetylcholinesterase. CONSTITUTION: A composition for improving memory power and learning ability including Artemisia apiaceae extract as an active ingredient. A composition for preventing or treating cognitive disorder includes the Artemisia apiaceae extract as the active ingredient. The compositions for improving memory power, learning ability, and preventing or treating cognitive disorder have several functions as follow: suppressing activity of Acetylcholinesterase, antioxidant activity, controlling or eliminating generation of reactive oxygen species, acting as antagonist [antagonist of NMDA[N-methyl-D-aspartate] receptor. The cognitive disorder stands for dementia, formerly LDH, agnosia, amnesia, aphasia, parectropia, or delirium. A pharmaceutical composition for preventing or treating cognitive disorder includes therapeutic effective amount of composition including Artemisia apiaceae extracts and pharmaceutically allowed carrier.
Abstract translation: 目的：提供一种用于提高记忆力和学习能力的组合物，其包括作为活性成分的姬松蒿提取物，以控制乙酰胆碱酯酶的抗氧化活性和活性。 构成：用于提高记忆力和学习能力的组合物，包括蒿科植物提取物作为活性成分。 用于预防或治疗认知障碍的组合物包括蒿科艾蒿提取物作为活性成分。 用于提高记忆力，学习能力和预防或治疗认知障碍的组合物具有以下功能：抑制乙酰胆碱酯酶的活性，抗氧化活性，控制或消除作为拮抗剂的活性氧的产生[NMDA [N-甲基 -D-天冬氨酸]受体。 认知障碍代表痴呆，以前称为LDH，恶性呕吐症，遗忘症，失语症，副作用或del妄。 用于预防或治疗认知障碍的药物组合物包括治疗有效量的组合物，包括蒿科植物提取物和药学上允许的载体。
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公开(公告)号：KR1020110135066A
公开(公告)日：2011-12-16
申请号：KR1020100054787
申请日：2010-06-10
Applicant: 한국식품연구원
Abstract: PURPOSE: Chitosan-tripolyphosphate(TPP) nano-particles and a method for manufacturing the same are provided to adjust the size of chitosan nano-particles and to reduce the coagulating phenomenon of the chitosan nano-particles by changing a homogenizing condition, an organic solvent, and a cross-linking agent in a nano-emulsion manufacturing process. CONSTITUTION: A method for manufacturing chitosan-tripolyphosphate nano-particles includes the following: A solution, in which a material to be collected in dichloromethane is dissolved, is applied to aqueous chitosan solution. An oil-in-water emulsion is formed by stirring and homogenizing the chitosan solution. The oil-in-water emulsion is mixed and reacted with TPP as a cross-linking agent. Dichloromethane is eliminated. The concentration of the aqueous chitosan solution is between 1.0 and 10.0%(w/v). The material to be collected in dichloromethane is s-allylcysteine, lycopene, beta-carotene, ellagic acid, anthocyanin, genistein, glutathione, and capsaicin.
Abstract translation: 目的：提供壳聚糖 - 三聚磷酸盐（TPP）纳米颗粒及其制备方法，以调节壳聚糖纳米颗粒的尺寸，并通过改变均质条件降低壳聚糖纳米颗粒的凝固现象，有机溶剂 ，和纳米乳液制造方法中的交联剂。 构成：用于制造壳聚糖 - 三聚磷酸盐纳米颗粒的方法包括以下步骤：将溶解二氯甲烷中收集的物质的溶液施加到壳聚糖水溶液中。 通过搅拌和均化壳聚糖溶液形成水包油乳液。 将水包油乳液与TPP作为交联剂混合并反应。 消除二氯甲烷。 壳聚糖水溶液的浓度为1.0至10.0％（w / v）。 在二氯甲烷中收集的物质是S-烯丙基半胱氨酸，番茄红素，β-胡萝卜素，鞣花酸，花青素，染料木素，谷胱甘肽和辣椒素。
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公开(公告)号：KR101049493B1
公开(公告)日：2011-07-15
申请号：KR1020100092045
申请日：2010-09-17
Applicant: 한국식품연구원
Abstract: PURPOSE: A composition containing Lepidium apefalum extract for enhancing memory and learning ability is provided to prevent or treat cognitive disorder. CONSTITUTION: A composition for enhancing memory and learning ability contains Lepidium apefalum extract as an active ingredient. A pharmaceutical composition for preventing and treating cognitive disorder contains Lepidium apefalum extract as an active ingredient. The Lepidium apefalum extract is prepared using a polar solvent or non-polar solvent. The polar solvent is water, alcohol, acetic acid, DMFO(dimethyl-formamide), and DMSO(dimethyl sulfoxide). The non-polar solvent is acetone, acetonitrile, ethyl acetate, methyl acetate, fluoroalkane, pentane, and hexane.
Abstract translation: 目的：提供含有提取记忆和学习能力的百日咳提取物的组合物，用于预防或治疗认知障碍。 构成：用于提高记忆力和学习能力的组合物，含有韭菜提取物作为活性成分。 一种用于预防和治疗认知障碍的药物组合物，含有虱属的提取物作为活性成分。 使用极性溶剂或非极性溶剂制备韭菜提取物。 极性溶剂是水，乙醇，乙酸，DMFO（二甲基甲酰胺）和DMSO（二甲基亚砜）。 非极性溶剂是丙酮，乙腈，乙酸乙酯，乙酸甲酯，氟烷烃，戊烷和己烷。
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公开(公告)号：KR1020090065616A
公开(公告)日：2009-06-23
申请号：KR1020070133004
申请日：2007-12-18
Applicant: 한국식품연구원
IPC: B01J13/02 , A01N25/28 , C07C233/20 , B82Y5/00
CPC classification number: A23P10/30 , B01J13/02 , B82Y40/00 , C07C233/20
Abstract: Provided are a process for preparing the nanocapsule comprising capsaicin, which improves the capsulation efficiency of capsaicin, and a nanocapsule comprising capsaicin prepared thereby. A process for preparing a nanocapsule comprising capsaicin comprises the steps of: mixing an organic solution with an aqueous solution to a mixing ratio of 0.1:20 to 1:20(v/v) and homogenizing the mixed solution to obtain an emulsion; and volatilizing an organic solvent from the emulsion to obtain a suspension and drying the suspension to obtain a nanocapsule comprising capsaicin. The organic solution is prepared by dissolving polycaprolactone and capsaicin into an organic solvent for capsaicin dispersion. The aqueous solution is prepared by dissolving a surfactant into distilled water.
Abstract translation: 提供制备包含辣椒素的纳米胶囊的方法，其提高辣椒素的包封效率，以及包含由其制备的辣椒素的纳米胶囊。 制备包含辣椒素的纳米胶囊的方法包括以下步骤：将有机溶液与水溶液混合至混合比为0.1:20至1:20（v / v），并均匀化混合溶液以获得乳液; 并从乳液中挥发有机溶剂以获得悬浮液并干燥该悬浮液以获得包含辣椒素的纳米胶囊。 有机溶液通过将聚己内酯和辣椒素溶解于有机溶剂中来制备辣椒素分散体。 通过将表面活性剂溶解在蒸馏水中制备水溶液。
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