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公开(公告)号：PL347552A1
公开(公告)日：2002-04-08
申请号：PL34755299
申请日：1999-10-28
Applicant: ABBOTT LAB
Inventor： CARROLL WILLIAM A , AGRIOS KONSTANTINOS A , ALTENBACH ROBERT J , DRIZIN IRENE , KORT MICHAEL E
IPC: C07D335/02 , A61K20060101 , A61K31/436 , A61K31/4365 , A61K31/437 , A61K31/4375 , A61K31/44 , A61K31/55 , A61P20060101 , A61P1/00 , A61P9/12 , A61P11/06 , A61P13/00 , A61P15/00 , A61P15/02 , A61P15/10 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/28 , C07C45/00 , C07C45/29 , C07C45/41 , C07C45/63 , C07C205/44 , C07D20060101 , C07D211/86 , C07D219/00 , C07D309/30 , C07D471/04 , C07D471/14 , C07D491/00 , C07D491/04 , C07D491/052 , C07D491/14 , C07D491/147 , C07D491/153 , C07D495/04 , C07D495/14 , C07D513/00
Abstract: The present invention provides novel compounds of formula I which may be useful in hyperpolarizing cell membranes, opening potassium channels, relaxing smooth muscle cells, and inhibiting bladder contractions.
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公开(公告)号：ZA200005798B
公开(公告)日：2002-01-18
申请号：ZA200005798
申请日：2000-10-18
Applicant: ABBOTT LAB
Inventor： CARROLL WILLIAM A , CHEN YIYUAN , DRIZIN IRENE , KERWIN JAMES F , MOORE JIMMIE L
IPC: A61K31/435 , A61P9/12 , A61P11/06 , A61P13/00 , A61P15/10 , A61P25/08 , A61P25/28 , C07C45/29 , C07D221/04 , C07D221/06 , C07D401/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D , A61K
Abstract: Compounds of formula Iare useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
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公开(公告)号：BG104999A
公开(公告)日：2001-10-31
申请号：BG10499900
申请日：2000-11-28
Applicant: ABBOTT LAB
Inventor： CARROLL WILLIAM A , CHEN YIYUAN , DRIZIN IRENE , KERWIN JAMES F , MOORE JIMMIE L
IPC: A61K31/435 , A61P9/12 , A61P11/06 , A61P13/00 , A61P15/10 , A61P25/08 , A61P25/28 , C07C45/29 , C07D221/04 , C07D221/06 , C07D401/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D211/82 , C07D215/20 , C07D211/90 , A61K31/473
Abstract: Compounds of formula are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal. 32 claims
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公开(公告)号：TR200003202T1
公开(公告)日：2001-08-21
申请号：TR200003202
申请日：2000-03-06
Applicant: ABBOTT LAB
Inventor： CARROLL WILLIAM A , CHEN YIYUAN , DRIZIN IRENE , KERWIN JAMES F , MOORE JIMMIE L
IPC: A61K31/435 , A61P9/12 , A61P11/06 , A61P13/00 , A61P15/10 , A61P25/08 , A61P25/28 , C07C45/29 , C07D221/04 , C07D221/06 , C07D401/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D211/82 , C07D215/20 , C07D211/90 , A61K31/473
Abstract: Compounds of formula Iare useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
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公开(公告)号：NO20012100L
公开(公告)日：2001-06-14
申请号：NO20012100
申请日：2001-04-27
Applicant: ABBOTT LAB
Inventor： CARROLL WILLIAM A , AGRIOS KONSTANTINOS A , ALTENBACH ROBERT J , DRIZIN IRENE , KORT MICHAEL E
IPC: C07D335/02 , A61K20060101 , A61K31/436 , A61K31/4365 , A61K31/437 , A61K31/4375 , A61K31/44 , A61K31/55 , A61P20060101 , A61P1/00 , A61P9/12 , A61P11/06 , A61P13/00 , A61P15/00 , A61P15/02 , A61P15/10 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/28 , C07C45/00 , C07C45/29 , C07C45/41 , C07C45/63 , C07C205/44 , C07D20060101 , C07D211/86 , C07D219/00 , C07D309/30 , C07D471/04 , C07D471/14 , C07D491/00 , C07D491/04 , C07D491/052 , C07D491/14 , C07D491/147 , C07D491/153 , C07D495/04 , C07D495/14 , C07D513/00
Abstract: The present invention provides novel compounds of formula I which may be useful in hyperpolarizing cell membranes, opening potassium channels, relaxing smooth muscle cells, and inhibiting bladder contractions.
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Patent Agency Ranking
公开(公告)号：NO20012100A
公开(公告)日：2001-06-14
申请号：NO20012100
申请日：2001-04-27
Applicant: ABBOTT LAB
Inventor： CARROLL WILLIAM A , AGRIOS KONSTANTINOS A , ALTENBACH ROBERT J , DRIZIN IRENE , KORT MICHAEL E
IPC: C07D335/02 , A61K20060101 , A61K31/436 , A61K31/4365 , A61K31/437 , A61K31/4375 , A61K31/44 , A61K31/55 , A61P20060101 , A61P1/00 , A61P9/12 , A61P11/06 , A61P13/00 , A61P15/00 , A61P15/02 , A61P15/10 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/28 , C07C45/00 , C07C45/29 , C07C45/41 , C07C45/63 , C07C205/44 , C07D20060101 , C07D211/86 , C07D219/00 , C07D309/30 , C07D471/04 , C07D471/14 , C07D491/00 , C07D491/04 , C07D491/052 , C07D491/14 , C07D491/147 , C07D491/153 , C07D495/04 , C07D495/14 , C07D513/00
CPC classification number: C07D471/04 , C07C45/00 , C07C45/298 , C07C45/41 , C07C45/63 , C07C205/44 , C07D471/14 , C07D491/14 , C07D495/14 , C07C47/565 , C07C47/55
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公开(公告)号：CA2391291A1
公开(公告)日：2001-05-25
申请号：CA2391291
申请日：2000-11-17
Applicant: ABBOTT LAB
Inventor： YI LIN , ZHANG HENRY Q , CARROLL WILLIAM A , HOLLADAY MARK W , DRIZIN IRENE
IPC: A61K31/519 , A61P1/04 , A61P1/14 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/06 , A61P13/08 , A61P13/10 , A61P13/12 , A61P15/00 , A61P15/06 , A61P15/08 , A61P15/10 , A61P17/14 , A61P25/08 , A61P25/28 , A61P29/00 , C07D487/04 , C07D491/14 , C07D495/14 , A61K31/505 , C07D231/00 , C07D239/00 , C07D307/00 , C07D335/00
Abstract: Compounds of formula (I), are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
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公开(公告)号：BG104594A
公开(公告)日：2001-03-30
申请号：BG10459400
申请日：2000-07-11
Applicant: ABBOTT LAB
Inventor： CARROL WILLIAM A , HOLLADAY MARK W , SULLIVAN JAMES P , DRIZIN IRENE , ZHANG HENRY Q
IPC: A61K31/4365 , A61K31/47 , A61K31/4743 , A61P1/00 , A61P1/14 , A61P9/08 , A61P9/12 , A61P11/06 , A61P13/02 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , C07C45/29 , C07D215/36 , C07D221/04 , C07D495/04 , C07D495/14 , C07D211/84 , A61K31/44 , A61K31/38
Abstract: Compounds having the formula are useful in treating diseases prevented by the ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal. 41 claims
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99.发明专利
公开(公告)号：CA2381252A1
公开(公告)日：2001-03-22
申请号：CA2381252
申请日：2000-09-14
Applicant: ABBOTT LAB
Inventor： DRIZIN IRENE , LI YIHONG , KINCAID JOHN F , BASHA ANWER , HAKEEM AHMED A , LIN NAN-HORNG , DONG LIMING
IPC: A61K31/4439 , A61K31/444 , A61K31/506 , A61K31/55 , A61P1/00 , A61P1/04 , A61P1/14 , A61P15/10 , A61P21/00 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P25/34 , C07D401/12 , C07D401/14 , C07D409/14 , A61K31/4427
Abstract: A series of 3-pyrrolidinyloxy-3'-pyridyl ether compounds, a method for selectively controlling neurotransmitter release in mammals using these compounds, and pharmaceutical compositions including these compounds. Preferred compounds are 3-pyrrolidinylmethoxy-3'-(5'-and/or 6'-substituted) pyridyl ethers.
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公开(公告)号：BR0005189A
公开(公告)日：2001-01-09
申请号：BR0005189
申请日：2000-03-06
Applicant: ABBOTT LAB
Inventor： CARROLL WILLIAM A , CHEN YIYUAN , DRIZIN IRENE , KERWIN JAMES F , MOORE JIMMIE L
IPC: A61K31/435 , A61P9/12 , A61P11/06 , A61P13/00 , A61P15/10 , A61P25/08 , A61P25/28 , C07C45/29 , C07D221/04 , C07D221/06 , C07D401/04 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D211/82 , C07D215/20 , C07D211/90 , A61K31/473
Abstract: Compounds of formula Iare useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
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