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公开(公告)号：WO0109096A3
公开(公告)日：2001-08-16
申请号：PCT/US0021054
申请日：2000-08-02
Applicant: ABBOTT LAB
Inventor： ALTENBACH ROBERT J , BAI HAO , BRIONI JORGE D , CARROLL WILLIAM A , GOPALAKRISHNAN MURALI , GREGG ROBERT J , HOLLADAY MARK W , HUANG PEGGY P , KINCAID JOHN F , KORT MICHAEL E , KYM PHILIP R , LYNCH JOHN K , PEREZ-MEDRANO ARTURO , ZHANG HENRY Q
IPC: C07D249/18 , A61K31/166 , A61K31/17 , A61K31/417 , A61K31/4192 , A61K31/44 , A61K31/4406 , A61K31/47 , A61P1/00 , A61P9/00 , A61P9/10 , A61P11/06 , A61P13/02 , A61P13/08 , A61P13/10 , A61P15/00 , A61P15/10 , A61P17/14 , A61P25/00 , A61P25/02 , A61P25/06 , A61P25/08 , C07C233/78 , C07C233/83 , C07C271/22 , C07C275/28 , C07C275/30 , C07C275/54 , C07C279/22 , C07C279/28 , C07C279/36 , C07C335/16 , C07C335/18 , C07C335/26 , C07D209/08 , C07D213/74 , C07D213/75 , C07D215/38 , C07D233/02 , C07D233/42 , C07D235/06 , C07D239/42 , C07D401/04 , C07D401/12 , C07D405/12 , C07D407/12 , A61K31/155 , C07C279/30
CPC classification number: C07D213/74 , A61K31/17 , C07C233/78 , C07C233/83 , C07C271/22 , C07C275/28 , C07C275/30 , C07C279/28 , C07C279/36 , C07C335/16 , C07C335/18 , C07D209/08 , C07D215/38 , C07D233/42 , C07D235/06 , C07D239/42 , C07D401/04 , C07D401/12 , C07D405/12
Abstract: Compounds of formula (I), are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
Abstract translation: 式（I）化合物可用于治疗钾通道开放剂所预防或改善的疾病。 还公开了钾通道开放组合物和在哺乳动物中打开钾通道的方法。
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公开(公告)号：WO0166534A3
公开(公告)日：2003-10-16
申请号：PCT/US0106885
申请日：2001-03-05
Applicant: ABBOTT LAB
Inventor： BENNANI YOUSSEF L , BLACK LAWRENCE A , DWIGHT WESLEY J , FAGHIH RAMIN , GENTLES ROBERT G , LIU HUAQING , PHELAN KATHLEEN M , VASUDEVAN ANIL , ZHANG HENRY Q
IPC: A61P37/08 , C07D205/04 , C07D205/08 , C07D207/08 , C07D207/16 , C07D213/56 , C07D233/54 , C07D239/10 , C07D243/08 , C07D271/06 , C07D277/30 , C07D295/205 , C07D307/68 , C07D333/24 , C07D403/06 , C07D405/12 , C07D413/12 , C07D413/14 , C07D417/14 , C07D487/08 , A61K31/495
CPC classification number: C07D207/08 , C07D205/04 , C07D205/08 , C07D207/16 , C07D213/56 , C07D233/64 , C07D239/10 , C07D243/08 , C07D271/06 , C07D277/30 , C07D295/205 , C07D307/68 , C07D333/24 , C07D403/06 , C07D405/12 , C07D413/12 , C07D413/14 , C07D417/14 , C07D487/08
Abstract: Compounds of formula (I), compounds of formula (II), compounds of formula (III), and compounds of formula (IV), or pharmaceutically acceptable salts thereof are useful as H3 receptor antagonists. Processes to make the compounds and methods of treatment using the compounds are also disclosed.
Abstract translation: 式（I）化合物，式（II）化合物，式（III）化合物和式（IV）化合物或其药学上可接受的盐可用作H3受体拮抗剂。 还公开了制备化合物的方法和使用该化合物的处理方法。
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公开(公告)号：WO2004060859A3
公开(公告)日：2004-09-02
申请号：PCT/US0338906
申请日：2003-12-08
Applicant: ABBOTT LAB
Inventor： ANDERSON STEVEN N , BHATIA PRAMILA , KOLASA TEODOZYJ , NAKANE MASAKI , PATEL MEENA V , ROHDE JEFFREY J , XIA ZHIREN , ZHANG HENRY Q
IPC: C07C323/62 , C07D211/16 , C07D211/34 , C07D211/42 , C07D211/46 , C07D211/62 , C07D213/70 , A61K31/165 , A61K31/44
CPC classification number: C07D213/70 , C07C323/62 , C07D211/16 , C07D211/34 , C07D211/42 , C07D211/46 , C07D211/62
Abstract: Compounds of formula (I) are useful for increasing cGMP levels in a mammal.
Abstract translation: 式（I）化合物可用于增加哺乳动物中的cGMP水平。
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公开(公告)号：WO02062762A3
公开(公告)日：2003-07-31
申请号：PCT/US0205252
申请日：2002-01-17
Applicant: ABBOTT LAB
Inventor： ALTENBACH ROBERT J , BAI HAO , BRIONI JORGE D , CARROLL WILLIAM A , GOPALAKRISHNAN MURALI , GREGG ROBERT J , HOLLADAY MARK W , HUANG PEGGY P , KINCAID JOHN F , KORT MICHAEL E , KYM PHILIP R , LYNCH JOHN K , PEREZ-MEDRANO ARTURO , ZHANG HENRY Q
IPC: A61K31/17 , A61K31/275 , A61K31/4164 , A61K31/4406 , A61K31/455 , A61K31/47 , A61K31/505 , A61P1/00 , A61P9/00 , A61P9/04 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/00 , A61P13/08 , A61P13/10 , A61P15/00 , A61P15/06 , A61P15/10 , A61P17/00 , A61P17/14 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/18 , A61P25/28 , A61P43/00 , C07C233/36 , C07C233/78 , C07C233/83 , C07C255/61 , C07C271/22 , C07C275/28 , C07C275/30 , C07C279/28 , C07C279/36 , C07C335/16 , C07C335/18 , C07C335/20 , C07D209/08 , C07D209/30 , C07D213/40 , C07D213/74 , C07D213/75 , C07D213/82 , C07D215/38 , C07D233/42 , C07D233/84 , C07D235/06 , C07D239/42 , C07D333/20 , C07D401/04 , C07D401/12 , C07D405/12 , C07D409/12
CPC classification number: C07D213/40 , A61K31/17 , A61K31/275 , A61K31/4406 , C07C233/78 , C07C233/83 , C07C271/22 , C07C275/28 , C07C275/30 , C07C279/28 , C07C279/36 , C07C335/16 , C07C335/18 , C07D209/08 , C07D213/74 , C07D213/75 , C07D213/82 , C07D215/38 , C07D233/42 , C07D233/84 , C07D235/06 , C07D239/42 , C07D333/20 , C07D401/04 , C07D401/12 , C07D405/12 , C07D409/12
Abstract: Compounds of formula (I) are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
Abstract translation: 式（I）化合物可用于治疗用钾通道开放剂预防或改善的疾病。 还公开了钾通道开放组合物和在哺乳动物中开放钾通道的方法。
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公开(公告)号：UY27820A1
公开(公告)日：2003-12-31
申请号：UY27820
申请日：2003-05-23
Applicant: ABBOTT LAB
Inventor： BHATIA PRAMILA A , DAANEN JEROME F , HAKEEM AHMED A , KOLASA TEODOZYI , MATULENKO MARK A , MORTELL KATHLEEN H , PATEL MEENA V , STEWART ANDREW O , WANG XUEQING , XIA ZHIREN , ZHANG HENRY Q
IPC: A61P15/10
Abstract: Uso de compuestos de fórmula ( I )) para el tratamiento de disfunciones sexuales y composiciones que contienen compuestos de fórmula ( I ) para el tratmiento de disfunciones sexuales.
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Patent Agency Ranking
公开(公告)号：CZ20002137A3
公开(公告)日：2000-10-11
申请号：CZ20002137
申请日：1998-12-16
Applicant: ABBOTT LAB
Inventor： CARROLL WILLIAM A , HOLLADAY MARK W , SULLIVAN JAMES P , DRIZIN IRENE , ZHANG HENRY Q
IPC: A61K31/38 , A61K31/44 , A61K31/47 , C07D211/84 , C07D215/36 , C07D221/00 , C07D333/00 , C07D337/00 , C07D495/04 , C07D495/14
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公开(公告)号：NO20003104D0
公开(公告)日：2000-06-16
申请号：NO20003104
申请日：2000-06-16
Applicant: ABBOTT LAB
Inventor： CARROLL WILLIAM A , HOLLADAY MARK W , SULLIVAN JAMES P , DRIZIN IRENE , ZHANG HENRY Q
IPC: A61K31/4365 , A61K31/47 , A61K31/4743 , A61P1/00 , A61P1/14 , A61P9/08 , A61P9/12 , A61P11/06 , A61P13/02 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , C07C45/29 , C07D215/36 , C07D221/04 , C07D495/04 , C07D495/14 , C07D
Abstract: Compounds having the formula are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
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公开(公告)号：CA2314948A1
公开(公告)日：1999-06-24
申请号：CA2314948
申请日：1998-12-16
Applicant: ABBOTT LAB
Inventor： HOLLADAY MARK W , CARROLL WILLIAM A , ZHANG HENRY Q , SULLIVAN JAMES P , DRIZIN IRENE
IPC: A61K31/4365 , A61K31/47 , A61K31/4743 , A61P1/00 , A61P1/14 , A61P9/08 , A61P9/12 , A61P11/06 , A61P13/02 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , C07C45/29 , C07D215/36 , C07D221/04 , C07D495/04 , C07D495/14 , C07D211/84 , C07D221/00 , C07D333/00 , C07D335/00 , C07D337/00 , A61K31/38 , A61K31/44
Abstract: Compounds having the formula (I) are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
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公开(公告)号：DE60227662D1
公开(公告)日：2008-08-28
申请号：DE60227662
申请日：2002-01-17
Applicant: ABBOTT LAB
Inventor： ALTENBACH ROBERT J , BAI HAO , BRIONI JORGE D , CARROL WILLIAM A , GOPALAKRISHNAN MURALI , HOLLADAY MARK W , HUANG PEGGY P , KINCAID JOHN F , KORT MICHAEL E , KYM PHILIP R , LYNCH JOHN K , PEREZ-MEDRANO ARTURO , ZHANG HENRY Q , GREGG ROBERT J
IPC: C07D213/75 , A61K31/17 , A61K31/275 , A61K31/4164 , A61K31/4406 , A61K31/455 , A61K31/47 , A61K31/505 , A61P1/00 , A61P9/00 , A61P9/04 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/00 , A61P13/08 , A61P13/10 , A61P15/00 , A61P15/06 , A61P15/10 , A61P17/00 , A61P17/14 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/18 , A61P25/28 , A61P43/00 , C07C233/36 , C07C233/78 , C07C233/83 , C07C255/61 , C07C271/22 , C07C275/28 , C07C275/30 , C07C279/28 , C07C279/36 , C07C335/16 , C07C335/18 , C07C335/20 , C07D209/08 , C07D209/30 , C07D213/40 , C07D213/74 , C07D213/82 , C07D215/38 , C07D233/42 , C07D233/84 , C07D235/06 , C07D239/42 , C07D333/20 , C07D401/04 , C07D401/12 , C07D405/12 , C07D409/12
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公开(公告)号：PT1040097E
公开(公告)日：2004-08-31
申请号：PT98963249
申请日：1998-12-16
Applicant: ABBOTT LAB
Inventor： CARROLL WILLIAM A , DRIZIN IRENE , SULLIVAN JAMES P , HOLLADAY MARK W , ZHANG HENRY Q
IPC: A61K31/4365 , A61K31/47 , A61K31/4743 , A61P1/00 , A61P1/14 , A61P9/08 , A61P9/12 , A61P11/06 , A61P13/02 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , C07C45/29 , C07D215/36 , C07D221/04 , C07D495/04 , C07D495/14 , C07D211/84 , A61K31/44 , A61K31/38
Abstract: Compounds having the formula are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
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