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公开(公告)号：RS58043B1
公开(公告)日：2019-02-28
申请号：RSP20181425
申请日：2013-04-23
Applicant: VERTEX PHARMA
Inventor： CHARIFSON PAUL S , COTTRELL KEVIN MICHAEL , DENG HONGBO , DUFFY JOHN P , GAO HUAI , GIROUX SIMON , GREEN JEREMY , JACKSON KATRINA LEE , MAXWELL JOHN PATRICK , MORRIS MARK A , PIERCE ALBERT CHARLES , WAAL NATHAN D , KENNEDY JOSEPH M , LAUFFER DAVID J , LEDEBOER MARK WILLEM , LI PAN , XU JINWANG
IPC: C07D401/14 , C07D239/42 , C07D401/04 , C07D403/04 , C07D403/10 , C07D405/14 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/10 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/04 , C07D491/048
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公开(公告)号：DK2841428T3
公开(公告)日：2018-12-10
申请号：DK13719359
申请日：2013-04-23
Applicant: VERTEX PHARMA
Inventor： GAO HUAI , DENG HONGBO , GIROUX SIMON , GREEN JEREMY , JACKSON KATRINA LEE , LI PAN , XU JINWANG , CHARIFSON PAUL S , COTTRELL KEVIN MICHAEL , DUFFY JOHN P , MAXWELL JOHN PATRICK , MORRIS MARK A , PIERCE ALBERT CHARLES , WAAL NATHAN D , KENNEDY JOSEPH M , LAUFFER DAVID J , LEDEBOER MARK WILLEM
IPC: C07D401/14 , C07D239/42 , C07D401/04 , C07D403/04 , C07D403/10 , C07D405/14 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/10 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/04 , C07D491/048
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公开(公告)号：PL3057959T3
公开(公告)日：2018-08-31
申请号：PL14800181
申请日：2014-10-17
Applicant: VERTEX PHARMA
Inventor： CHARIFSON PAUL S , COTTRELL KEVIN MICHAEL , DENG HONGBO , DUFFY JOHN P , GAO HUAI , GIROUX SIMON , GREEN JEREMY , JACKSON KATRINA LEE , KENNEDY JOSEPH M , LAUFFER DAVID J , LEDEBOER MARK WILLEM , LI PAN , MAXWELL JOHN PATRICK , MORRIS MARK A , PIERCE ALBERT CHARLES , WAAL NATHAN D , XU JINWANG
IPC: C07D403/12 , A61K31/506 , A61P35/00 , C07D401/14 , C07D403/14 , C07D405/14 , C07D471/04 , C07D493/04
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公开(公告)号：HRP20180804T1
公开(公告)日：2018-08-10
申请号：HRP20180804
申请日：2018-05-22
Applicant: VERTEX PHARMA
Inventor： CHARIFSON PAUL S , COTTRELL KEVIN MICHAEL , DENG HONGBO , DUFFY JOHN P , GAO HUAI , GIROUX SIMON , GREEN JEREMY , JACKSON KATRINA LEE , KENNEDY JOSEPH M , LAUFFER DAVID J , LEDEBOER MARK WILLEM , LI PAN , MAXWELL JOHN PATRICK , MORRIS MARK A , PIERCE ALBERT CHARLES , WAAL NATHAN D , XU JINWANG
IPC: C07D403/12 , A61K31/506 , A61P35/00 , C07D401/14 , C07D403/14 , C07D405/14 , C07D471/04 , C07D493/04
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公开(公告)号：SI3057959T1
公开(公告)日：2018-07-31
申请号：SI201430733
申请日：2014-10-17
Applicant: VERTEX PHARMA
Inventor： CHARIFSON PAUL S , COTTRELL KEVIN MICHAEL , DENG HONGBO , DUFFY JOHN P , GAO HUAI , GIROUX SIMON , GREEN JEREMY , JACKSON KATRINA LEE , KENNEDY JOSEPH M , LAUFFER DAVID J , LEDEBOER MARK WILLEM , LI PAN , MAXWELL JOHN PATRICK , MORRIS MARK A , PIERCE ALBERT CHARLES , WAAL NATHAN D , XU JINWANG
IPC: C07D403/00 , A61K31/00 , A61P35/00 , C07D401/00 , C07D405/00 , C07D471/00 , C07D493/00
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Patent Agency Ranking
公开(公告)号：AU2013251804B2
公开(公告)日：2017-10-12
申请号：AU2013251804
申请日：2013-04-23
Applicant: VERTEX PHARMA
Inventor： GAO HUAI , CHARIFSON PAUL S , COTTRELL KEVIN MICHAEL , DENG HONGBO , DUFFY JOHN P , GIROUX SIMON , GREEN JEREMY , JACKSON KATRINA LEE , MAXWELL JOHN PATRICK , MORRIS MARK A , PIERCE ALBERT CHARLES , WAAL NATHAN D , LAUFFER DAVID J , KENNEDY JOSEPH M , LEDEBOER MARK WILLEM , LI PAN , XU JINWANG
IPC: C07D401/14 , C07D239/42 , C07D401/04 , C07D403/04 , C07D403/10 , C07D405/14 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/10 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/04 , C07D491/048
Abstract: The present invention relates to compounds of following formula (I) useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders, such as cancer.
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公开(公告)号：HK1220190A1
公开(公告)日：2017-04-28
申请号：HK16108234
申请日：2016-07-13
Applicant: VERTEX PHARMA
Inventor： MAXWELL JOHN PATRICK , CHARIFSON PAUL S , TANG QING , RONKIN STEVEN M , JACKSON KATRINA LEE , PIERCE ALBERT CHARLES , LAUFFER DAVID J , LI PAN , GIROUX SIMON , XU JINWANG , MORRIS MARK A , COURT JOHN J , COTTRELL KEVIN M , DENG HONGBO , WAAL NATHAN D , GU WENXIN
IPC: C07D20060101 , A61K20060101 , A61P20060101
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公开(公告)号：AU2014244555A1
公开(公告)日：2015-10-15
申请号：AU2014244555
申请日：2014-03-12
Applicant: VERTEX PHARMA
Inventor： MAXWELL JOHN PATRICK , CHARIFSON PAUL S , TANG QING , RONKIN STEVEN M , JACKSON KATRINA LEE , PIERCE ALBERT CHARLES , LAUFFER DAVID J , LI PAN , GIROUX SIMON , XU JINWANG , COTTRELL KEVIN M , MORRIS MARK A , WAAL NATHAN D , COURT JOHN J , GU WENXIN , DENG HONGBO
IPC: C07D403/12 , A61K31/517 , A61P35/00 , C07D405/12 , C07D413/04 , C07D417/12 , C07D491/052
Abstract: The present invention relates to compounds (I) useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
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公开(公告)号：IN999DEN2012A
公开(公告)日：2015-04-10
申请号：IN999DEN2012
申请日：2012-02-03
Applicant: VERTEX PHARMA
Inventor： HENDERSON JAMES A , MAXWELL JOHN , VAILLANCOURT LOUIS , MORRIS MARK , GREY JR RONALD , GIROUX SIMON , KONG LAVAL CHAN CHUN , DAS SANJOY KUMAR , LIU BINGCAN , POISSON CARL , CADILHAC CAROLINE , BUBENIK MONICA , REDDY T JAGADEESWAR , FALARDEAU GUY , YANNOPOULOS CONSTANTIN , WANG JIAN , PEREIRA OSWY Z , BENNANI YOUSSEF L , PIERCE ALBERT C , BHISETTI GOVINDA RAO , COTTRELL KEVIN M , MARONE VALERIE
IPC: C07D401/14
Abstract: Compounds represented by formula (I) or pharmaceutically acceptable salts and solvates thereof, where A, B, B', X, Y, Rl', R2', R3', R5, R5', R6, m, n, or p are as defined herein, are useful for treating flaviviridae viral infections.
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公开(公告)号：SG11201406584TA
公开(公告)日：2014-11-27
申请号：SG11201406584T
申请日：2013-04-23
Applicant: VERTEX PHARMA
Inventor： CHARIFSON PAUL S , COTTRELL KEVIN MICHAEL , GAO HUAI , DENG HONGBO , DUFFY JOHN P , GIROUX SIMON , GREEN JEREMY , JACKSON KATRINA LEE , MAXWELL JOHN PATRICK , MORRIS MARK A , PIERCE ALBERT CHARLES , WAAL NATHAN D , LAUFFER DAVID J , KENNEDY JOSEPH M , LEDEBOER MARK WILLEM , LI PAN , XU JINWANG
IPC: C07D401/14 , C07D239/42 , C07D401/04 , C07D403/04 , C07D403/10 , C07D405/14 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/10 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/04 , C07D491/048
Abstract: The present invention relates to compounds useful as inhibitors of DNA-PK. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
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