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公开(公告)号：KR1020100095309A
公开(公告)日：2010-08-30
申请号：KR1020090014521
申请日：2009-02-20
Applicant: 강원대학교산학협력단 , 주식회사 그래미
Abstract: PURPOSE: A method for iextracting Rhodiola sachalinensis immunity as an active ingredient is provided to introduce the ultra high pressure and to ensure high immunity and reduced toxicity. CONSTITUTION: A Rhodiola sachalinensis effective ingredient with immunity is isolated by extracting at ultra high pressure. A method for extracting the effective ingredient with Rhodiola sachalinensis immunity comprises: a step of extracting Rhodiola sachalinensis at 500Mpa for 5-15 minutes; and a step of extracting with the distillation water at 60°C.
Abstract translation: 目的：提供一种提取红景天免疫力作为活性成分的方法，以引入超高压，并确保高免疫力和降低毒性。 构成：通过在超高压下提取，分离出具有免疫力的红景天有效成分。 用红景天免疫提取有效成分的方法包括：以500Mpa提取红景天5-15分钟的步骤; 以及在60℃下用蒸馏水进行萃取的工序。
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公开(公告)号：KR101035009B1
公开(公告)日：2011-05-17
申请号：KR1020090043391
申请日：2009-05-19
Applicant: 강원대학교산학협력단
Abstract: 본 발명은 피부 미백 효과를 가지는 당귀의 알지네이트 나노 입자화를 이용한 클렌징 조성물의 제조방법 및 그 제조물에 관한 것으로서, 본 발명은 기본적으로 알지네이트로 당귀의 저온열수추출물을 나노입자화하여 클렌징 조성물을 제조하는 것을 특징으로 한다.
본 발명에 따르면 저온 열수 추출 공정을 통해 당귀로부터 활성 물질의 파괴 없이 유효 성분을 얻을 수 있다. 또한 당귀의 알지네이트에 의한 나노 입자화를 통해, 저온 추출로 용출된 유용 생리 활성 물질이 효과적인 방법으로 피부에 전달되고 잔류될 수 있어, 미백활성 증진을 위한 향장품으로서의 당귀의 가치가 크게 증진된다.
당귀, 나노입자, 클렌징 조성물-
13.发明公开
公开(公告)号：KR1020120118326A
公开(公告)日：2012-10-26
申请号：KR1020110035821
申请日：2011-04-18
Applicant: 강원대학교산학협력단
IPC: A23L3/3472 , A23P1/02
CPC classification number: A23L3/3472 , A23L33/105 , A23V2200/10
Abstract: PURPOSE: A natural edible antimicrobial agent for food using the composite nanonization of a Japanese horseradish extract, and a producing method thereof are provided to reduce the unique smell of Japanese horseradish, and to maintain the quality of the food. CONSTITUTION: A producing method of a natural edible antimicrobial agent for food using the composite nanonization of a Japanese horseradish extract comprises the following steps: crushing Japanese horseradish, mixing the crushed Japanese horseradish with distilled water, tween-20, and homogenizing the mixture in a homogenizer; passing the obtained Japanese horseradish fluid through a micro-tube in the high pressure of 20,000-30,000psi for homogenizing the Japanese horseradish into the nano size; repeating the homogenizing process for 1-10 times; mixing and dissolving lecithin in a container with chloroform, and removing the chloroform using a decompressor to obtain multi-layers of the lecithin; inserting the Japanese horseradish fluid into the container with the multi-layers; and dispersing the Japanese horseradish fluid using ultrasonic waves for 30-40 minutes. [Reference numerals] (AA) Conventional single nanonization process; (BB) New complex nanonization process; (CC) Microfluidizer process: Japanese horseradish nanoparticles with the coagulating particles and Japanese horseradish smell; (DD) Homogenizer process: emulsified and homogenized Japanese horseradish samples; (EE) Ultrasonic dispersion process: Japanese horseradish nanoparticles with low collection rate, and unstable to the external environment; (FF) Microfluidizer process: homogenizing the Japanese horseradish nanoparticles; (GG) Japanese horseradish nanoparticles with low collection rate, and unstable to the external environment; (HH) Collecting the Japanese horseradish samples with lecithin for reducing the smell; (II) Japanese horseradish nanoparticles with high uniformity and collection rate, without the smell
Abstract translation: 目的：提供使用日本辣根提取物的复合纳米化的食品的天然可食用抗微生物剂及其制备方法，以减少日本辣根的独特气味，并保持食品的质量。 构成：使用日本辣根提取物的复合纳米化处理的食品天然可食用抗微生物剂的制造方法，包括以下步骤：粉碎日本辣根，将破碎的日本辣根与蒸馏水混合，tween-20，并将混合物均质化 均质; 将获得的日本辣根液通过20,000-3000psi的高压微管，使日本辣根均匀化成纳米尺寸; 重复匀浆过程1-10次; 将卵磷脂与氯仿混合溶解于容器中，用减压剂除去氯仿，得到多层卵磷脂; 将日本辣根流体用多层插入容器中; 并使用超声波将日本辣根分散液分散30-40分钟。 （标号）（AA）常规单纳米化方法; （BB）新的复合纳米化过程; （CC）微流化法：日本辣根纳米颗粒与凝结颗粒和日本辣根气味; （DD）均化器工艺：乳化均匀日本辣根样品; （EE）超声波分散工艺：采收率低的日本辣根纳米颗粒，对外界环境不稳定; （FF）微流化工艺：均化日本辣根纳米粒子; （GG）日本辣根纳米粒子，收集率低，对外部环境不稳定; （HH）采用卵磷脂收集日本辣根素，减少气味; （二）日本辣根纳米粒子具有高均匀性和收集率，无异味
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公开(公告)号：KR101143363B1
公开(公告)日：2012-05-09
申请号：KR1020090120496
申请日：2009-12-07
Applicant: 강원대학교산학협력단
Abstract: 본 발명은 키토산을 이용하여 병출의 면역 증진용 성분을, 흡수가 용이하고 식용에 적합하도록 나노입자로 제조하는 방법 및 그 방법에 의해 제조된 나노입자 등에 관한 것이다. 상기 목적을 달성하기 위한 본 발명의 나노입자 제조 방법은 병풀 내 수용성 성분의 용출을 위한 용매 추출공정 및 수용성 추출물의 나노입자화라는 단계를 거쳐 시행된다.
보다 구체적으로 본 발명의, 키토산을 이용한 병풀의 면역 증진 성분의 식용 나노입자 제조방법은,
(1) 종래의 공지된 방법에 따라 수용성 용매를 사용하여 병풀 내 수용성 유효성분을 추출하는 단계;
(2) 하기 (3)의 병풀 수용성 추출물 수용액 대비 0.05 내지 0.5 중량%의 키토산을 약산성의 용매에 녹여 상온에서 다시 증발 건조시키는 방법으로 키토산의 박막 유상을 만드는 단계; 및
(3) 위 키토산의 박막 유상을, 0.1 내지 1.0 mg/mL 농도의 병풀 수용성 성분의 수용액과 혼합 분산하여 w/o(water in oil) 형식의 나노입자를 제조하는 단계;로 이루어진다.
병풀, 수용성 추출물, 키토산, 식용 나노입자-
公开(公告)号：KR1020110101657A
公开(公告)日：2011-09-16
申请号：KR1020100020818
申请日：2010-03-09
Applicant: 강원대학교산학협력단
IPC: A23G3/48
CPC classification number: A23G3/48 , A23G2200/14 , A23L33/105 , A23V2002/00 , A23V2200/25 , A23V2200/324
Abstract: 본 발명은 참당귀(
Angelica
gigas ) 수용성 추출물의 나노입자화를 이용한 소아용 면역 증진용 캔디류 제조방법에 관한 것이다.
본 발명에 따른, 참당귀 수용성 추출물의 나노입자화를 이용한 소아용 면역 증진용 캔디의 제조방법은, 젤라틴으로 참당귀의 열수추출물을 나노입자화하여 제조하는 것을 특징으로 한다.
본 발명에 따를 경우 나노입자화한 참당귀 추출물의 효과적인 세포 투과 기능으로 인해 적은 농도의 추출물로도 높은 활성을 기대할 수 있으므로 비용과 시간 면에서 경제적이다. 또한 쓴맛을 가지는 당귀를 젤라틴으로 포집하여 캔디로 만듦으로써 고유의 진한 냄새를 줄이고 향미를 증진시켜 어린이들도 쉽게 섭취할 수 있다.-
Patent Agency Ranking
公开(公告)号：KR1020110069432A
公开(公告)日：2011-06-23
申请号：KR1020090126164
申请日：2009-12-17
Applicant: 강원대학교산학협력단
CPC classification number: B01D15/265 , A61K36/29 , B01D11/0265 , B01D11/04
Abstract: PURPOSE: A separation method of natural coniferyl alcohol from berberis koreana bark, and the natural coniferyl alcohol are provided to obtain the coniferyl alcohol capable of using as a natural flavor. CONSTITUTION: A separation method of natural coniferyl alcohol from berberis koreana bark comprises the following steps: obtaining a hot water extract from the berberis koreana bark; inserting a mixed solution of hexane and butanol into the hot water extract for separating a water layer, and a mixed solution layer of the hexane and the butanol; inserting ethyl acetate and chloroform solution into the water layer for separating the water layer and the ethyl acetate and chloroform solution layer; powdering the ethyl acetate and chloroform solution layer; applying n-haxane and acetone to TLC as a developing solvent, for dividing the TLC into 7 divided materials; separating the 7 divided materials into 12 divided materials using the column chromatography using benzene, ethly acetate, and silica gel; separating the 12 divided materials into 3 divided materials using the column chromatography using Sephadex LH-20; and selecting one material from the 3 divided materials.
Abstract translation: 目的：提供白桦树皮天然松柏醇和天然松柏醇的分离方法，以获得能够作为天然风味使用的松柏醇。 构成：从白桦木皮中分离出天然松柏醇的方法，包括以下步骤：从小檗皮树皮获得热水提取物; 将己烷和丁醇的混合溶液插入到用于分离水层的热水提取物中，以及己烷和丁醇的混合溶液层; 将乙酸乙酯和氯仿溶液插入水层，分离水层和乙酸乙酯和氯仿溶液层; 粉化乙酸乙酯和氯仿溶液层; 将正哈烷和丙酮施加到TLC作为显影溶剂，将TLC分解成7种分开的材料; 使用苯，乙酸乙酯和硅胶使用柱色谱法将7种分开的材料分成12种分开的材料; 使用Sephadex LH-20的柱色谱法将12种分割的材料分成3种分开的材料; 并从3种材料中选择一种材料。
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17.发明公开고로쇠 또는 우산고로쇠 수액이 함유된 기능성 요구르트의 제조방법 및 그 요구르트 有权含有ACER MONO和ACER OKAMOTOANUM的SAP的功能性YOGURT的制备方法和YOGURT
公开(公告)号：KR1020110009459A
公开(公告)日：2011-01-28
申请号：KR1020090066866
申请日：2009-07-22
Applicant: 강원대학교산학협력단
CPC classification number: A23C9/137 , A23C9/1238
Abstract: PURPOSE: A producing method of functional yogurt using acer mono max sap is provided to offer useful bioactive substances and the fresh flavor of the acer mono max sap to the yogurt. CONSTITUTION: A producing method of functional yogurt using acer mono max sap comprises the following steps: doubling boiling milk, and injecting inoculum of lactic acid bacteria; stirring the mixture, and adding acer mono max sap or acer okamotoanum sap; and fermenting the mixture for 5hours at 40~42deg C after sealing a container to make pasty yogurt.
Abstract translation: 目的：提供功能性酸奶的生产方法，使用acer mono max sap提供有用的生物活性物质和酸奶的新鲜味道。 构成：使用苹果汁最大汁液的功能性酸奶的生产方法包括以下步骤：加热沸腾的牛奶和注射乳酸菌的接种物; 搅拌混合物，加入苹果汁或猕猴桃汁; 并在密封容器后，在40〜42℃下将混合物发酵5小时，制成糊状酸奶。
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公开(公告)号：KR1020100114713A
公开(公告)日：2010-10-26
申请号：KR1020090033227
申请日：2009-04-16
Applicant: 강원대학교산학협력단
CPC classification number: A23L19/09 , A23L33/105 , A23P10/40 , A23V2002/00 , A23V2250/21 , A61K36/17
Abstract: PURPOSE: A preparing method of ephedra sinca nanoparticles for activity of skin aging inhibition for the anti-wrinkle activity is provided to remove the smell of the Ephedrae Herba characteristic and obtain the Ephedrae Herba particle without the break down of the active material of the Ephedrae Herba. CONSTITUTION: An Ephedrae Herba is shattered. The distilled water of drainage is to solvent and the pulverized Ephedrae Herba is hot water extraction performed in 60 degrees for 24 hours the low temperature. After the hot water extract is filtered to a vacuum filtering device and makes with the powder. The powder is warmed with the concentration of 1mg/ml in the distilled water. The chloroform flies and the multilayer of the lecithin are formed by using decompressor.
Abstract translation: 目的：提供麻黄素纳米颗粒的抗皱作用皮肤衰老抑制活性的制备方法，以消除麻黄草特征的气味，获得麻黄草颗粒，不会破坏麻黄片的活性物质 。 构成：麻黄草被粉碎。 排水的蒸馏水是溶剂，粉碎的麻黄草是在60度低温下进行热水提取24小时。 将热水提取物过滤至真空过滤装置并与粉末混合。 将粉末在蒸馏水中以1mg / ml的浓度加热。 氯仿苍蝇，卵磷脂多层通过减压剂形成。
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公开(公告)号：KR1020100095304A
公开(公告)日：2010-08-30
申请号：KR1020090014510
申请日：2009-02-20
Applicant: 강원대학교산학협력단
CPC classification number: A23L19/00 , A23L33/105 , A23V2002/00 , A23V2250/2124 , A23V2300/14
Abstract: PURPOSE: An extraction method of useful physiologically active components from low quality fresh ginseng is provided to effectively use the active components as a food material. CONSTITUTION: An extraction method of useful physiologically active components from low quality fresh ginseng comprises the following steps: washing the low quality fresh ginseng, and cutting the ginseng with the size of 1~2 centimeters; and adding 10 times of distilled water to the cut ginseng as an extraction solvent, and high pressure and high temperature extracting for 20 minutes.
Abstract translation: 目的：提供低质量新鲜人参的有用的生理活性成分的提取方法，有效地将活性成分用作食品。 构成：低质量新鲜人参的有用的生理活性成分的提取方法包括以下步骤：洗涤低质量的新鲜人参，切割1〜2厘米的人参; 并加入10倍的蒸馏水作为萃取溶剂，并进行高压和高温萃取20分钟。
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公开(公告)号：KR1020100088251A
公开(公告)日：2010-08-09
申请号：KR1020090007332
申请日：2009-01-30
Applicant: 강원대학교산학협력단 , 최영범
Abstract: PURPOSE: A method for extracting Ulva pertusa kjellman with enhanced immunity is provided to easily elute useful ingredients by extracting Ulva pertusa kjellman in a short time at high temperature and high pressure. CONSTITUTION: A method for extracting Ulva pertusa kjellman with improved immunity comprises: a step of sealing dried Ulva pertusa kjellman and water in a container of high temperature and high pressure; a step of extracting at 120-150Mpa and 110-120°C for 1-5 minutes; a step of filtering the extract; and a step of decompressing and freeze-drying.
Abstract translation: 目的：提供免疫力强的方法，可以在短时间内在高温高压下提取Ul extracting。。。。。。。。。。。。。。。。。。。。。。。。。。。。。。。 构成：提高免疫力的方法，包括：将高温高压容器中干燥的乌贼属和水分封闭的步骤; 在120-150Mpa和110-120℃下提取1-5分钟的步骤; 过滤提取物的步骤; 和减压和冷冻干燥的步骤。
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