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公开(公告)号：KR101373263B1
公开(公告)日：2014-03-13
申请号：KR1020120141590
申请日：2012-12-07
Applicant: 한국식품연구원
IPC: A61K31/70 , A61K31/7016 , A61K31/7008 , A61P37/00
CPC classification number: A61K31/7004 , A61K31/7008 , A61K31/7016 , A61K31/715 , A61K36/44
Abstract: 본 발명은 감잎 유래 다당 분획물 및 이의 제조방법에 관한 것으로, 좀 더 상세하게는 전체 감잎 다당 분획물 대비 중성 다당(neutral sugar)은 70 내지 90 중량%, 우론산(uronic acid)은 10 내지 30 중량% 인 것을 특징으로 하는 감잎 유래 다당 분획물, 이의 제조 방법 및 이의 용도에 관한 것이다.
본 발명의 다당 분획물은 보체계의 활성을 증강시키고, 정상 마우스 및 면역억제 마우스 모두에서 면역 기능을 증진시키는 효능이 매우 뛰어나 경쟁력 있는 면역 증강용 식품용 조성물 및 면역 증강용 의약품 제조에 효과적이다.-
公开(公告)号：KR1020130115949A
公开(公告)日：2013-10-22
申请号：KR1020120038793
申请日：2012-04-13
Applicant: 한국식품연구원
IPC: A61K36/906 , A61P21/00
Abstract: PURPOSE: A pharmaceutical composition with enhanced antioxidation activity is provided to protect damaged muscle tissues caused by reactive oxygen. CONSTITUTION: A pharmaceutical composition with enhanced antioxidation activity contains an extract of matured Zingiber officinale Roscoe. The matured Zingiber officinale Roscoe is stored at 70-90°C and a humidity of 70-90% for 5-15 days. The extract reduces oxidative damages of muscle tissues. A health food with enhanced antioxidation activity contains the extract.
Abstract translation: 目的：提供具有增强抗氧化活性的药物组合物，以保护由活性氧引起的受损肌肉组织。 构成：具有增强抗氧化活性的药物组合物含有成熟的姜黄提取物。 成熟的Zingiber officinale Roscoe在70-90℃和70-90％的湿度下储存5-15天。 提取物减少肌肉组织的氧化损伤。 具有增强抗氧化活性的保健食品含有提取物。
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公开(公告)号：KR1020130066823A
公开(公告)日：2013-06-21
申请号：KR1020110133506
申请日：2011-12-13
Applicant: 한국식품연구원
CPC classification number: A23L19/03 , A23F3/30 , A23L3/0155 , A23L3/40 , A23V2002/00 , A23V2200/30 , A23V2250/2124
Abstract: PURPOSE: A manufacturing method of red ginseng is provided to prevent a browning phenomenon, to maintain the original shape thereof, and to have excellent extraction yields within a short period of time. CONSTITUTION: A manufacturing method of red ginseng comprises a step of high temperature and high pressure treating ginseng with 5 kgf/cm^2 at 130-155 °C; a step of drying ginseng to a moisture content of 10-5 wt; a step of rapidly cooling the ginseng to 20-45 °C. The vacuum drying step is conducted at 22-32 °C for 12-18 hours. Before the high temperature and high pressure treatment, pre-drying up to a moisture content of 5-45 wt% is conducted. The pre-drying is conducted at 45-60 °C for 20-100 hours.
Abstract translation: 目的：提供红参的制造方法，以防止褐变现象，维持其原始形状，并在短时间内具有优异的提取率。 构成：人参的制造方法包括在130-155℃下5kgf / cm 2的高温高压处理人参的步骤; 将人参干燥至10-5重量％的水分含量的步骤; 将人参快速冷却至20-45°C的步骤。 真空干燥步骤在22-32℃下进行12-18小时。 在高温高压处理之前，进行预干燥至含水量为5-45重量％的水分。 预干燥在45-60℃进行20-100小时。
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公开(公告)号：KR1020120114077A
公开(公告)日：2012-10-16
申请号：KR1020110031834
申请日：2011-04-06
Applicant: 한국식품연구원
IPC: A61K31/198 , A61K36/8962 , A61P35/00
Abstract: PURPOSE: A method for maintaining antioxidation function of garlic extract is provided to maintain storage stability and to maintain antioxidation function of allinase. CONSTITUTION: A method for maintaining antioxidation function comprises a step of homogenizing allinase, surfactant, and oil. The surfactant is propylene glycol monostearate or polyglycerol polyricinoleate. Allinase is extracted from garlic. A composition with maintained antioxidation function contains surfactant and oil-coated allinase.
Abstract translation: 目的：提供维持大蒜提取物抗氧化功能的方法，保持贮藏稳定性，维持蒜素的抗氧化功能。 构成：维持抗氧化功能的方法包括使蒜素，表面活性剂和油匀浆的步骤。 表面活性剂是丙二醇单硬脂酸酯或聚甘油多蓖麻油酸酯。 蒜素从大蒜中提取。 具有维持抗氧化功能的组合物含有表面活性剂和油包衣的allinase。
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公开(公告)号：KR1020120108480A
公开(公告)日：2012-10-05
申请号：KR1020110026381
申请日：2011-03-24
Applicant: 한국식품연구원
IPC: A23B7/148 , A23L27/10 , A23L3/3418
CPC classification number: A23B7/148 , A23L3/3418 , A23L27/10
Abstract: PURPOSE: A preserving method of ginger using a gas substitution process is provided to package and store the peeled ginger at the proper temperature for maintaining the freshness of the ginger. CONSTITUTION: A preserving method of ginger using a gas substitution process comprises the following steps: inserting the ginger into a packaging container; and filling the packaging container with air containing nitrogen, oxygen, and carbon dioxide. The volume ratio of the oxygen and the carbon dioxide is 1:1-4. The volume ratio of the nitrogen, the oxygen, and the carbon dioxide is 70:15:15. The ginger is stored at 5-15 deg C. [Reference numerals] (AA) Weight reduction(%); (BB) Storage period(days)
Abstract translation: 目的：提供使用气体置换过程的姜的保存方法，以将去皮的姜包装并储存在适当的温度下，以保持姜的新鲜度。 构成：使用气体替代方法的姜的保存方法包括以下步骤：将姜插入包装容器中; 并用包含氮气，氧气和二氧化碳的空气填充包装容器。 氧气和二氧化碳的体积比为1：1-4。 氮气，氧气和二氧化碳的体积比为70:15:15。 姜存放在5-15℃。[参考号]（AA）减重量（％） （BB）储存期（天）
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Patent Agency Ranking
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公开(公告)号：KR1020110135066A
公开(公告)日：2011-12-16
申请号：KR1020100054787
申请日：2010-06-10
Applicant: 한국식품연구원
Abstract: PURPOSE: Chitosan-tripolyphosphate(TPP) nano-particles and a method for manufacturing the same are provided to adjust the size of chitosan nano-particles and to reduce the coagulating phenomenon of the chitosan nano-particles by changing a homogenizing condition, an organic solvent, and a cross-linking agent in a nano-emulsion manufacturing process. CONSTITUTION: A method for manufacturing chitosan-tripolyphosphate nano-particles includes the following: A solution, in which a material to be collected in dichloromethane is dissolved, is applied to aqueous chitosan solution. An oil-in-water emulsion is formed by stirring and homogenizing the chitosan solution. The oil-in-water emulsion is mixed and reacted with TPP as a cross-linking agent. Dichloromethane is eliminated. The concentration of the aqueous chitosan solution is between 1.0 and 10.0%(w/v). The material to be collected in dichloromethane is s-allylcysteine, lycopene, beta-carotene, ellagic acid, anthocyanin, genistein, glutathione, and capsaicin.
Abstract translation: 目的：提供壳聚糖 - 三聚磷酸盐（TPP）纳米颗粒及其制备方法，以调节壳聚糖纳米颗粒的尺寸，并通过改变均质条件降低壳聚糖纳米颗粒的凝固现象，有机溶剂 ，和纳米乳液制造方法中的交联剂。 构成：用于制造壳聚糖 - 三聚磷酸盐纳米颗粒的方法包括以下步骤：将溶解二氯甲烷中收集的物质的溶液施加到壳聚糖水溶液中。 通过搅拌和均化壳聚糖溶液形成水包油乳液。 将水包油乳液与TPP作为交联剂混合并反应。 消除二氯甲烷。 壳聚糖水溶液的浓度为1.0至10.0％（w / v）。 在二氯甲烷中收集的物质是S-烯丙基半胱氨酸，番茄红素，β-胡萝卜素，鞣花酸，花青素，染料木素，谷胱甘肽和辣椒素。
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公开(公告)号：KR1020110082280A
公开(公告)日：2011-07-19
申请号：KR1020100002183
申请日：2010-01-11
Applicant: 한국식품연구원
Abstract: PURPOSE: Ginseng coffee using an extract of puffed ginseng, and a producing method thereof are provided to secure the excellent storage property, and to offer the unique flavor of the ginseng. CONSTITUTION: A producing method of ginseng coffee comprises the following steps: dipping green coffee beans into a ginseng extract; drying the green coffee beans dipped in the ginseng extract; and roasting the green coffee beans. The dipping process of the green coffee beans to the ginseng extract is capable of being replaced as a spraying process of a coating solution containing the ginseng extract for forming a coating layer.
Abstract translation: 目的：提供使用膨化人参提取物的人参咖啡及其制备方法，以确保优异的保存性，并提供人参的独特风味。 构成：人参咖啡的生产方法包括以下步骤：将绿咖啡豆浸入人参提取物中; 干燥浸泡在人参提取物中的生咖啡豆; 并烘焙生咖啡豆。 生咖啡豆对人参提取物的浸渍过程能够作为含有用于形成涂层的人参提取物的涂布溶液的喷涂方法进行更换。
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公开(公告)号：KR1020100020606A
公开(公告)日：2010-02-23
申请号：KR1020080079279
申请日：2008-08-13
Applicant: 한국식품연구원
CPC classification number: A61K8/97 , A61K2236/333 , A61Q17/04 , A61Q19/02 , Y10S514/844
Abstract: PURPOSE: A cosmetic composition for skin whitening containing grape branch extract is provided to suppress tyrosinase activity and melanogenesis without less side effects. CONSTITUTION: A cosmetic composition for skin whitening contains 0.001-10 weight parts of grape branch extract as an active ingredient. The used grape is obtained from Campbell or Neo Muscat. The grape branch extract contains procyanidin B2. The grape branch extract is obtained using distilled water, organic solvent of 1-20 carbon atoms or their mixture solvent. A organic solvent is low alcohol of 1-4 carbon atoms, acetone, ethylacetate, ether, methylene chloride, ethylene chloride, hexane or diethyl ether. The cosmetic composition is used in the form of skin softener, nutrition skin, nutrition cream, massage cream, essence, or pack.
Abstract translation: 目的：提供含有葡萄枝提取物的美白组合物，用于抑制酪氨酸酶活性和黑素生成，而不会减少副作用。 构成：用于皮肤美白的化妆品组合物含有0.001-10重量份的葡萄枝提取物作为活性成分。 二手葡萄从Campbell或Neo Muscat获得。 葡萄枝提取物含有原花青素B2。 使用蒸馏水，1-20碳原子的有机溶剂或其混合溶剂获得葡萄枝提取物。 有机溶剂是1-4个碳原子的低级醇，丙酮，乙酸乙酯，乙醚，二氯甲烷，二氯乙烷，己烷或乙醚。 化妆品组合物以皮肤柔软剂，营养皮肤，营养霜，按摩霜，精华液或包装的形式使用。
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公开(公告)号：KR1020090070305A
公开(公告)日：2009-07-01
申请号：KR1020070138273
申请日：2007-12-27
Applicant: 한국식품연구원
IPC: A61K36/258 , A61K36/074 , A61P3/10
Abstract: A polysaccharide fraction for reducing blood sugar, which produced by fermenting the Ganoderma lucidum(KCTC 6532) is provided to improve the function related to insulin resistance and suppress the apoptosis of pancreatic beta cell. A method for manufacturing a polysaccharide fraction for reducing blood sugar comprises: a step of fermenting a ginseng with a Gnoderma lucidum; a step of filtering the fermented material with distilled water; and a step of mixing the filtered solution and ethanol and obtaining precipitate of polysaccharide fraction. The Ganoderma lucidum is Ganoderma lucidum(KCTC 6532) The polysaccharide fraction increases the activity of glucokinase in a hepatocyte, and increases the phosphorylation of AkT protein, activates AMPK(AMP-activated protein kinase), and suppress the apoptosis of pancreatic beta cell.
Abstract translation: 提供了通过发酵灵芝（KCTC 6532）产生的用于降低血糖的多糖部分，以改善与胰岛素抵抗相关的功能并抑制胰腺β细胞的凋亡。 制备用于降低血糖的多糖部分的方法包括：用灵芝发酵人参的步骤; 用蒸馏水过滤发酵物料的步骤; 和将过滤的溶液和乙醇混合并获得多糖级分的沉淀物的步骤。 灵芝灵芝（KCTC 6532）多糖级分增加肝细胞中葡萄糖激酶的活性，增加AkT蛋白磷酸化，激活AMPK（AMP激活蛋白激酶），抑制胰腺β细胞凋亡。
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