公开(公告)号：BR9711777A

公开(公告)日：1999-08-24

申请号：BR9711777

申请日：1997-09-11

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN ,  ROSENBERG JOERG

IPC: A61J3/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22

Abstract: A process for producing solid dose forms by mixing at least one polymeric binder, with or without at least one active ingredient and with or without conventional additives, and shaping the mixture, where at least one of the components is employed in liquid form.

公开(公告)号：CA2311308A1

公开(公告)日：1999-06-10

申请号：CA2311308

申请日：1998-11-30

Applicant: BASF AG

Inventor： ERNST ANDREAS ,  MEFFERT HELMUT ,  SANNER AXEL ,  KOTHRADE STEPHAN ,  BERNDL GUNTHER

IPC: A61K47/32 ,  A23K20/10 ,  A23K40/10 ,  A23K40/20 ,  A23L27/00 ,  A23L33/10 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22 ,  A61K31/277 ,  A61K31/421 ,  A61K47/30

Abstract: The invention relates to a method for producing solid dosing forms by mixing at least one polymeric binding agent, at least one active substance, and optional common additives while producing a plastic mixture and during shaping, whereby a copolymer from a N-vinyl lactam and from an copolymerizable monomer with a hydrophobic radical is used as a polymeric binding agent. Dosing forms which slowly release the active substance are obtained in a simple and economical manner.

公开(公告)号：AU4384697A

公开(公告)日：1998-04-02

申请号：AU4384697

申请日：1997-09-11

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN ,  ROSENBERG JOERG

IPC: A61J3/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22

Abstract: A process for producing solid dose forms by mixing at least one polymeric binder, with or without at least one active ingredient and with or without conventional additives, and shaping the mixture, where at least one of the components is employed in liquid form.

公开(公告)号：ZA966058B

公开(公告)日：1998-01-19

申请号：ZA966058

申请日：1996-07-17

Applicant: BASF AG

Inventor： HUCKESTEIN BRIGITTA ,  RENZ HANS ,  KOTHRADE STEPHAN ,  HAEBERLE KARL

IPC: C08L75/04 ,  C07C265/14 ,  C08G18/00 ,  C08G18/08 ,  C08G18/62 ,  C08G18/70 ,  C08G18/79 ,  C08L75/00 ,  C09D175/00 ,  C09D175/04 ,  C09J175/00 ,  C09J175/04 ,  C08I ,  C08K ,  C08G ,  C08J ,  C08D

Abstract: Water-emulsifiable polyisocyanates (I) comprise: (A) (cyclo)aliphatic or aromatic polyisocyanates; and (B) reaction prods. contg. at least one reactive NCO gp. and made by reacting (A) with polyvinyl pyrrolidones (PVP's). Pref. the PVP content of the (A)+(B) compsn. is 1-20 wt.%. The PVP, which esp. contains one or more NCO- reactive OH gps., is of Mn 400-40000. The (I)-contg. aq. dispersions are based on polyurethanes or radically-polymerised polymers.

公开(公告)号：CA2265532C

公开(公告)日：2006-04-04

申请号：CA2265532

申请日：1997-09-11

Applicant: BASF AG

Inventor： KOTHRADE STEPHAN ,  ROSENBERG JOERG ,  KLEINKE ANDREAS ,  BREITENBACH JORG

IPC: A61J3/00 ,  A61K9/20 ,  A61K9/16 ,  A61K9/22 ,  A61K47/30

Abstract: The present invention relates to a process for producing solid dosage forms by mixing at least one polymer binder, possibly at least one active substance and possibly the usual additives, as well as products derived from this mixture, of which at least one component is added in liquid state.

公开(公告)号：DE59909945D1

公开(公告)日：2004-08-19

申请号：DE59909945

申请日：1999-09-23

Applicant: BASF AG

Inventor： KOTHRADE STEPHAN ,  BERNDL GUNTHER ,  MEFFERT HELMUT

IPC: A61K9/20 ,  A61K9/22 ,  A61K9/32 ,  A61K9/42 ,  A61K7/48

Abstract: The present invention relates to a solid dosage form comprising at least one polymeric binder and at least one active ingredient and, where appropriate, conventional additives, wherein the polymeric binder consists of copolymerized units a) 15-83% by weight of at least one N-vinyllactam, b) 15-83% by weight of methyl methacrylate, c) 2-70% by weight of at least one other monomer and d) 0-9.9% by weight of at least one alpha,beta-ethylenically unsaturated acid.

公开(公告)号：DE59909717D1

公开(公告)日：2004-07-22

申请号：DE59909717

申请日：1999-03-22

Applicant: BASF AG

Inventor： KOTHRADE STEPHAN ,  BERNDL GUNTHER ,  SIMON DIRK ,  SANNER AXEL

IPC: A23L33/00 ,  A61K9/20 ,  A61K9/22 ,  A61K47/32 ,  A61K47/34 ,  C08F279/02 ,  C08L51/04

Abstract: Solid dosage forms containing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives, wherein a physiologically tolerated, water-swellable graft copolymer or a mixture of graft copolymers is employed as polymeric binder.

公开(公告)号：DE10108387A1

公开(公告)日：2002-08-29

申请号：DE10108387

申请日：2001-02-21

Applicant: BASF AG

Inventor： MEFFERT HELMUT ,  SANNER AXEL ,  TIEFENSEE KRISTIN ,  KOTHRADE STEPHAN

IPC: A61K9/06 ,  A61K8/00 ,  A61K8/30 ,  A61K8/31 ,  A61K8/34 ,  A61K8/36 ,  A61K8/37 ,  A61K8/72 ,  A61K8/90 ,  A61K31/4164 ,  A61K47/32 ,  A61P17/16 ,  A61Q3/02 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q17/02 ,  A61Q19/00 ,  A61Q19/10 ,  C08F216/18 ,  C08F218/04 ,  C08F220/00 ,  C08F226/06 ,  C11D3/37 ,  A61K7/00 ,  A61K7/06 ,  A61K7/48

Abstract: The invention relates to cosmetic or pharmaceutical agents having a liquid or gel consistency and containing at least one copolymer that, in turn, contains at least one N-vinyl lactam and at least one ethylenically unsaturated monomer with a longer-chain alkyl radical or alkenyl radical, said N-vinyl lactam and monomer being incorporated by polymerization in the copolymer. The invention also relates to the use of copolymers of the aforementioned type in cosmetic or pharmaceutical compositions.

公开(公告)号：AT220897T

公开(公告)日：2002-08-15

申请号：AT98965716

申请日：1998-11-30

Applicant: BASF AG

Inventor： KOTHRADE STEPHAN ,  MEFFERT HELMUT ,  BERNDL GUNTHER ,  ERNST ANDREAS ,  SANNER AXEL

IPC: A61K47/32 ,  A23K20/10 ,  A23K40/10 ,  A23K40/20 ,  A23L27/00 ,  A23L33/10 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22 ,  A61K31/277 ,  A61K31/421

Abstract: Solid dosage forms are obtained by mixing at least one polymeric binder, at least one active ingredient, and, where appropriate, conventional additives to form a plastic mixture, and shaping, using as polymeric binder a copolymer of an N-vinyllactam and a copolymerizable monomer having a hydrophobic radical. Dosage forms which show slow release of the active ingredient are obtained in a simple and low-cost manner.

公开(公告)号：DE59706066D1

公开(公告)日：2002-02-21

申请号：DE59706066

申请日：1997-09-29

Applicant: BASF AG

Inventor： NIESSNER MANFRED ,  NILZ CLAUDIA ,  HOESSEL PETER ,  KOTHRADE STEPHAN ,  SANNER AXEL

IPC: A61K8/00 ,  A61K8/36 ,  A61K8/42 ,  A61K8/49 ,  A61K8/72 ,  A61K8/81 ,  A61K8/898 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/04 ,  A61Q5/10 ,  A61Q5/12 ,  A61Q11/00 ,  A61Q19/00 ,  C08F226/02 ,  C08F226/06 ,  A61K7/06 ,  A61K7/48

Abstract: A cosmetic composition comprising water-soluble copolymer, which as characteristic structural elements comprisesa) vinylcarboxamide units of the general formula IwhereR1 and R2 independently of one another are H, alkyl, cycloalkyl, aryl or aralkyl, andb) units of the general formula IIwhereA is a chemical bond or an alkylene group,the radicals R3 independently of one another are H, alkyl, cycloalkyl, aryl or aralkyl, or together with the nitrogen atom to which they are bonded, form an unsubstituted, mono- or polysubstituted, five- to seven-membered, heterocyclic, aromatic or nonaromatic ring, which if appropriate contains one or two further heteroatoms, selected from among O, N and S, it being possible for the heterocyclic ring to be fused to a further five- or six-membered, aromatic or nonaromatic ring,R4 is H, alkyl or aralkyl.