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公开(公告)号:DE69209513T2
公开(公告)日:1996-09-12
申请号:DE69209513
申请日:1992-09-22
Applicant: KAO CORP
Inventor: OHASHI YUKIHIRO , FUJIMORI TAKETOSHI , NAGAI MINORU , KAWAMATA AKIRA , YADA YUKIHIRO , HIGUCHI KAZUHIKO , IMOKAWA GENJI , TAKEMA YOSHINORI , SAKAINO YUKIKO , OGAWA AYUMI , FUJIMURA TSUTOMU
Abstract: PCT No. PCT/JP92/01210 Sec. 371 Date Mar. 23, 1994 Sec. 102(e) Date Mar. 23, 1994 PCT Filed Sep. 22, 1992 PCT Pub. No. WO93/05763 PCT Pub. Date Apr. 1, 1993A composition for external skin care comprising an amine derivative represented by the following formula (1), (1) wherein R1 is a linear, branched, or cyclic saturated or unsaturated hydrocarbon group having 4-40 carbon atoms, and R2, R3, R4, R5 and R6 are individually a hydrogen atom or a hydrocarbon group having 1-10 carbon atoms, which may be substituted or unsubstituted by 1 or more hydroxy groups; or an acid addition salt thereof, in an amount from 0.0001 to less than 0.1% by weight; and a method of curing wrinkles and keratinization of the skin characterized by applying said amine derivative or its salt to the skin.
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公开(公告)号:DE3850795T2
公开(公告)日:1995-03-09
申请号:DE3850795
申请日:1988-03-07
Applicant: KAO CORP
Inventor: OTSUJI KAZUYA , HONDA YASUKI , OKAMOTO KIKUHIKO , INAOKA HAKARU , TAKANO SATOSHI , SUGIMURA YUKIO , OKAMURA NORIKO , SAITO KAZUMI , TAKEMA YOSHINORI , SUZUKI TOSHIYUKI
IPC: A61K8/73 , A61K31/715 , A61Q5/02 , A61Q19/00 , A61Q19/10 , C08B37/00 , C09J105/00 , C09K3/00 , C11D3/22 , C12N5/04 , C12P19/04 , C12R1/91 , A61K7/02 , C11D3/00
Abstract: A novel acidic heteropolysaccharide which comprises as its structural units arabinose, mannose, galactose, glucuronic acid, and xylose, at a specific ratio. The polysaccharide can be prepared by culturing a callus induced from a plant belonging to the genus Polianthes L. in a culture medium containing plant hormones. The polysaccharide can be used as a compoinent of agents for external application and detergents, and provides good moisturizing effects and a smooth, satisfying feeling upon use. When formulated in detergents, they produce remarkable improvement in a clean, rich feeling upon use.
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公开(公告)号:AT52908T
公开(公告)日:1990-06-15
申请号:AT84112727
申请日:1984-10-22
Applicant: KAO CORP
Inventor: TAKEMA YOSHINORI , TSUSHIMA RIKIO , YASUDA YUTAKA , KONO YOSHINAO
IPC: C08F16/00 , A61K8/00 , A61K8/02 , A61K8/04 , A61K8/72 , A61K8/81 , A61Q3/02 , A61Q19/00 , C08F16/02 , C08F216/06 , A61K7/00
Abstract: A film-forming cosmetic composition useful as a facial pack, nail enamel, eye liner etc., which comprises a copolymer of vinyl alcohol and alkyl vinyl ether, being referred to simply as PVA/AVE, consisting of 98 to 80 mole% of vinyl alcohol monomer units and 2 to 20 mole% of linear or branched alkyl vinyl monomer units having from 1 to 6 carbon atoms.The molar ratio of the vinyl alcohol monomer units to the alkyl vinyl ether monomer units is in the range of from 95/5 to 85/15.The PVA/AVE according to the invention has no acetic groups with ester bonds in a molecule. Instead, there are alkyl or alkenyl groups having ether bonds which serve for steric hindrance for preventing gelation of an aqueous solution of such copolymer. From this reason, the PVA/AVE does not undergo any hydrolysis as time passes and is thus excellent in storage stability.
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公开(公告)号:EP0965327A4
公开(公告)日:2001-08-29
申请号:EP97943153
申请日:1997-10-08
Applicant: KAO CORP
Inventor: FUJIMURA TSUTOMU , ITO NORIKO , NAGAI MINORU , ONO TOSHIYA , YAMAMURO AKIRA , TAKEMA YOSHINORI
IPC: A01N43/00 , A01N43/36 , A01N43/40 , A01N43/58 , A01N43/64 , A61K6/00 , A61K8/49 , A61K31/395 , A61K31/397 , A61K31/40 , A61K31/41 , A61K31/435 , A61K31/445 , A61K31/495 , A61K31/50 , A61K31/535 , A61P17/00 , A61Q19/08 , A61K7/48 , A61K7/00
CPC classification number: A61Q19/08 , A61K8/49 , A61K8/4913 , A61K8/4926 , A61K8/494
Abstract: Wrinkling modifiers and anti-aging cosmetic preparations which contain guanidine derivatives of general formula (1) or salts thereof, wherein (a) is a group derived from a heterocyclic compound selected from among azetidine, pyrrolidine, piperidine, piperazine and morpholine; and R and R are each independently hydrogen, alkyl, hydroxyl, hydroxyalkyl, carboxyl, carboxyalkyl or amidino. The cosmetic preparations are excellent in the effect of suppressing wrinkling and the effect of making wrinkles disappear and exhibit an excellent feeling in use.
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公开(公告)号:EP0755671A4
公开(公告)日:1997-04-09
申请号:EP95914561
申请日:1995-04-11
Applicant: KAO CORP
Inventor: YAMAGUCHI MASAKAZU , KAWAMATA AKIRA , OHSU HIROYUKI , TAKEMA YOSHINORI , IMOKAWA GENJI
CPC classification number: A61Q17/04 , A61K8/4973 , A61Q19/08
Abstract: A dermatologic preparation containing a furan derivative represented by general formula (1) as the active ingredient, wherein X represents optionally substituted furan, benzofuran or isobenzofuran residue; and R and R represent each C1-C8 linear, branched or cyclic alkyl which may be substituted by X-CH2-N(R )- (wherein R represents C1-C6 linear or branched alkyl; and X is as defined above), or R and R together with the adjacent nitrogen atom may form a heterocycle which may be substituted by X-CH2- (wherein X is as defined above). The preparation is excellent in the effect of inhibiting wrinkling due to exposure to ultraviolet radiations, especially UV-B, and hence useful for the inhibition of wrinkling.
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公开(公告)号:DE69732796D1
公开(公告)日:2005-04-21
申请号:DE69732796
申请日:1997-10-08
Applicant: KAO CORP
Inventor: FUJIMURA TSUTOMU , ITO NORIKO , NAGAI MINORU , ONO TOSHIYA , YAMAMURO AKIRA , TAKEMA YOSHINORI
IPC: A01N43/00 , A01N43/36 , A01N43/40 , A01N43/58 , A01N43/64 , A61K6/00 , A61K8/49 , A61K31/395 , A61K31/397 , A61K31/40 , A61K31/41 , A61K31/435 , A61K31/445 , A61K31/495 , A61K31/50 , A61K31/535 , A61P17/00 , A61Q19/08 , A61K7/48 , A61K7/00
Abstract: Wrinkling modifiers and anti-aging cosmetic preparations which contain guanidine derivatives of general formula (1) or salts thereof, wherein (a) is a group derived from a heterocyclic compound selected from among azetidine, pyrrolidine, piperidine, piperazine and morpholine; and R and R are each independently hydrogen, alkyl, hydroxyl, hydroxyalkyl, carboxyl, carboxyalkyl or amidino. The cosmetic preparations are excellent in the effect of suppressing wrinkling and the effect of making wrinkles disappear and exhibit an excellent feeling in use
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公开(公告)号:DE69419601T2
公开(公告)日:1999-12-02
申请号:DE69419601
申请日:1994-03-17
Applicant: KAO CORP
Inventor: OHASHI YUKIHIRO , YADA YUKIHIRO , TAKEMA YOSHINORI , FUJIMORI TAKETOSHI , KAWAMATA AKIRA , OHSU HIROYUKI , HIGUCHI KAZUHIKO , IMOKAWA GENJI , KUSUOKU HIROSHI , OGAWA AYUMI , FUJIMURA TSUTOMU
IPC: A61K8/41 , A61K8/46 , A61K8/49 , A61K8/68 , A61K31/13 , A61Q17/04 , A61Q19/00 , A61Q19/08 , C07C215/08 , C07C215/10 , C07C215/12 , C07C217/28 , C07C219/06 , C07C229/12 , C07C229/24 , C07C233/18 , C07C235/10 , C07C237/06 , C07C323/25 , C07D295/088 , C07D311/58 , C07D311/72 , C07D317/22 , C07F7/08 , C07F9/09 , C07H15/04 , A61K7/48
Abstract: An amine derivative of following general formula (I) or (II) (wherein R represents a heteroatom-containing C1-C40 hydrocarbon group which may have a ring structure, etc.; R to R each represent a C1-C10 hydrocarbon group, hydrogen, etc.; A represents (i) or R -Z-R (CH2)n-; B represents hydrogen, a C1-C10 hydrocarbon group, nitrogen, etc.; and C represents hydrogen, a C1-C10 hydrocarbon group, nitrogen, alcohol residue, phosphoric acid residue, etc.); a dermatologic preparation containing the same; and a process for producing the amine derivative. The amine derivative has excellent effects of smoothing wrinkles and improving keratodermia.
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公开(公告)号:DE3850795D1
公开(公告)日:1994-09-01
申请号:DE3850795
申请日:1988-03-07
Applicant: KAO CORP
Inventor: OTSUJI KAZUYA , HONDA YASUKI , OKAMOTO KIKUHIKO , INAOKA HAKARU , TAKANO SATOSHI , SUGIMURA YUKIO , OKAMURA NORIKO , SAITO KAZUMI , TAKEMA YOSHINORI , SUZUKI TOSHIYUKI
IPC: A61K8/73 , A61K31/715 , A61Q5/02 , A61Q19/00 , A61Q19/10 , C08B37/00 , C09J105/00 , C09K3/00 , C09K23/56 , C11D3/22 , C12N5/04 , C12P19/04 , C12R1/91 , A61K7/02 , C11D3/00
Abstract: A novel acidic heteropolysaccharide which comprises as its structural units arabinose, mannose, galactose, glucuronic acid, and xylose, at a specific ratio. The polysaccharide can be prepared by culturing a callus induced from a plant belonging to the genus Polianthes L. in a culture medium containing plant hormones. The polysaccharide can be used as a compoinent of agents for external application and detergents, and provides good moisturizing effects and a smooth, satisfying feeling upon use. When formulated in detergents, they produce remarkable improvement in a clean, rich feeling upon use.
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公开(公告)号:HK33991A
公开(公告)日:1991-05-10
申请号:HK33991
申请日:1990-05-02
Applicant: KAO CORP
Inventor: TAKEMA YOSHINORI , TSUSHIMA RIKIO , YASUDA YUTAKA , KONO YOSHINAO
IPC: C08F16/00 , A61K8/00 , A61K8/02 , A61K8/04 , A61K8/72 , A61K8/81 , A61Q3/02 , A61Q19/00 , C08F16/02 , C08F216/06 , A61K7/00
Abstract: A film-forming cosmetic composition useful as a facial pack, nail enamel, eye liner etc., which comprises a copolymer of vinyl alcohol and alkyl vinyl ether, being referred to simply as PVA/AVE, consisting of 98 to 80 mole% of vinyl alcohol monomer units and 2 to 20 mole% of linear or branched alkyl vinyl monomer units having from 1 to 6 carbon atoms.The molar ratio of the vinyl alcohol monomer units to the alkyl vinyl ether monomer units is in the range of from 95/5 to 85/15.The PVA/AVE according to the invention has no acetic groups with ester bonds in a molecule. Instead, there are alkyl or alkenyl groups having ether bonds which serve for steric hindrance for preventing gelation of an aqueous solution of such copolymer. From this reason, the PVA/AVE does not undergo any hydrolysis as time passes and is thus excellent in storage stability.
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公开(公告)号:JP2004189740A
公开(公告)日:2004-07-08
申请号:JP2003408899
申请日:2003-12-08
Inventor: OHASHI YUKIHIRO , FUJIMORI TAKETOSHI , KAWAMATA AKIRA , YADA YUKIHIRO , HIGUCHI KAZUHIKO , TAKEMA YOSHINORI , FUJIMURA TSUTOMU , IMOKAWA GENJI
IPC: A61K8/30 , A61K8/02 , A61K8/06 , A61K8/40 , A61K8/41 , A61K8/44 , A61K8/55 , A61K8/58 , A61K8/60 , A61K7/00
Abstract: PROBLEM TO BE SOLVED: To provide an external preparation for skin, having an excellent effect of preventing/improving wrinkles, making the skin maintain its normal function, and excellent in a dandruff-resisting effect and an effect of improving the skin after sunburned.
SOLUTION: This external preparation for skin contains an amine derivative expressed by general formula (1) (R
1 is a 1-40C hydrocarbon radical which may contain one or more hetero atoms; R
2 and R
3 are each a 1-3C bivalent hydrocarbon radical; R
4 is H or a 1-3C hydrocarbon radical; R
5 is H, a 1-3C hydrocarbon radical or -P(O)(OH)
2 ; R
6 is H or a 1-3C hydrocarbon radical which may have one or more hydroxy group; and Y is a 1-10C hydrocarbon radical which has one or more radicals, such as hydroxy group, alkoxy group, phosphate and carboxyl group) or general formula (2) (R
7 and R
8 are each a 1-3C hydrocarbon radical which may have one to three hydroxy groups).
COPYRIGHT: (C)2004,JPO&NCIPI
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