公开(公告)号：HRP20240935T1

公开(公告)日：2024-11-22

申请号：HRP20240935

申请日：2019-06-25

Applicant: PTC THERAPEUTICS INC

Inventor： SYDORENKO NADIYA ,  ALAM MD RAUFUL ,  ARNOLD MICHAEL A ,  BABU SURESH ,  BHATTACHARYYA ANURADHA ,  CHEN GUANGMING ,  GERASYUTO ALEKSEY I ,  KARP GARY MITCHELL ,  KASSICK ANDREW J ,  MAZZOTTI ANTHONY R ,  MOON YOUNG-CHOON ,  NARASIMHAN JANA ,  PATEL JIGAR ,  TURPOFF ANTHONY ,  WOLL MATTHEW G ,  YAN WUMING ,  ZHANG NANJING

IPC: C07D487/04 ,  A61K31/4985 ,  A61K31/5025 ,  A61P25/00 ,  A61P25/14 ,  A61P25/28 ,  C07D491/04 ,  C07D495/04 ,  C07D519/00

公开(公告)号：CO2024000890A2

公开(公告)日：2024-04-29

申请号：CO2024000890

申请日：2024-01-30

Applicant: PTC THERAPEUTICS INC

Inventor： KARP GARY MITCHELL ,  BABU SURESH ,  ALAM RAUFUL ,  BHATTACHARYYA ANURADHA ,  CHEN GUANGMING ,  EASTWOOD MATTHEW S ,  HOSSEYNI SEYEDMORTEZA ,  JIANG YAO ,  MOON YOUNG-CHOON ,  NARASIMHAN JANA ,  REN HONGYU ,  SYDORENKO NADIYA ,  WOLL MATTHEW G ,  ZHANG NANJING

IPC: C07D487/04 ,  A61K31/5025 ,  A61P25/14 ,  A61P25/28

Abstract: La presente descripción se refiere a compuestos, formas y composiciones farmacéuticas de los mismos y métodos de uso de dichos compuestos, formas o composiciones de los mismos para tratar o mejorar la enfermedad de Huntington. En particular, la presente descripción se refiere a compuestos de heteroarilo bicíclicos sustituidos, formas y composiciones farmacéuticas de los mismos y métodos de uso de dichos compuestos, formas o composiciones de los mismos para tratar o mejorar la enfermedad de Huntington.

公开(公告)号：AU2021254418A1

公开(公告)日：2022-11-03

申请号：AU2021254418

申请日：2021-04-08

Applicant: PTC THERAPEUTICS INC

Inventor： SYDORENKO NADIYA ,  ALAM RAUFUL ,  BABU SURESH ,  BHATTACHARYYA ANURADHA ,  CHEN GUANGMING ,  CHIERCHIA MATTEO ,  KARP GARY MITCHELL ,  LUONG TOM TUAN ,  MAZZOTTI ANTHONY R ,  MOON YOUNG-CHOON ,  MSZAR NICHOLAS WALTER ,  NARASIMHAN JANA ,  PATEL JIGAR S ,  REN HONGYU ,  WANG GANG ,  WOLL MATTHEW G ,  ZHANG NANJING ,  ZHANG XIAOYAN

IPC: C07D401/14 ,  A61K31/53 ,  A61P25/28 ,  C07D403/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D487/04 ,  C07D491/04 ,  C07D498/04 ,  C07D513/04

Abstract: The present description relates to compounds of Formula (I), forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

公开(公告)号：AU2019294482B2

公开(公告)日：2022-09-01

申请号：AU2019294482

申请日：2019-06-25

Applicant: PTC THERAPEUTICS INC

Inventor： ZHANG NANJING ,  BABU SURESH ,  BARRAZA SCOTT J ,  BHATTACHARYYA ANURADHA ,  CHEN GUANGMING ,  KARP GARY MITCHELL ,  KASSICK ANDREW J ,  MAZZOTTI ANTHONY R ,  MOON YOUNG-CHOON ,  NARASIMHAN JANA ,  SYDORENKO NADIYA ,  TURPOFF ANTHONY ,  WOLL MATTHEW G ,  YAN WUMING

IPC: C07D417/14 ,  A61K31/4439 ,  A61K31/454 ,  A61K31/46 ,  A61K31/496 ,  A61K31/5025 ,  A61K31/519 ,  A61K31/55 ,  A61P25/00 ,  A61P25/14 ,  A61P25/28 ,  C07D471/04 ,  C07D487/04 ,  C07D513/04 ,  C07D519/00

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted benzothiazole compounds of Formula (I) or (II), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

公开(公告)号：AU2022209304A1

公开(公告)日：2022-08-25

申请号：AU2022209304

申请日：2022-07-28

Applicant: PTC THERAPEUTICS INC

Inventor： ZHANG NANJING ,  BABU SURESH ,  BARRAZA SCOTT J ,  BHATTACHARYYA ANURADHA ,  CHEN GUANGMING ,  KARP GARY MITCHELL ,  KASSICK ANDREW J ,  MAZZOTTI ANTHONY R ,  MOON YOUNG-CHOON ,  NARASIMHAN JANA ,  SYDORENKO NADIYA ,  TURPOFF ANTHONY ,  WOLL MATTHEW G ,  YAN WUMING

IPC: C07D417/14 ,  A61K31/4439 ,  A61K31/454 ,  A61K31/46 ,  A61K31/496 ,  A61K31/5025 ,  A61K31/519 ,  A61K31/55 ,  A61P25/00 ,  A61P25/14 ,  A61P25/28 ,  C07D471/04 ,  C07D487/04 ,  C07D513/04 ,  C07D519/00

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. W3 R2 R 3 X (I) (II) In particular, the present description relates to substituted benzothiazole compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

公开(公告)号：SG11202112504YA

公开(公告)日：2021-12-30

申请号：SG11202112504Y

申请日：2020-05-12

Applicant: PTC THERAPEUTICS INC

Inventor： SYDORENKO NADIYA ,  ALAM MD RAUFUL ,  AMEDZO LUKIANA ,  ARNOLD MICHAEL A ,  BABU SURESH ,  BHATTACHARYYA ANURADHA ,  KARP GARY MITCHELL ,  KENTON NATHANIEL T ,  LUONG TOM TUAN ,  MAZZOTTI ANTHONY R ,  MOON YOUNG-CHOON ,  MORRILL CHRISTIE ,  NARASIMHAN JANA ,  MSZAR NICHOLAS WALTER ,  PATEL JIGAR S ,  REN HONGYU ,  TURPOFF ANTHONY ,  WANG GANG ,  WOLL MATTHEW G ,  ZHANG NANJING ,  ZHANG XIAOYAN

IPC: C07D401/14 ,  A61K31/501 ,  A61K31/53 ,  A61P25/28 ,  C07D413/14 ,  C07D417/14 ,  C07D487/04

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), Formula (II), or Formula (III), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

公开(公告)号：HUE055031T2

公开(公告)日：2021-10-28

申请号：HUE16874024

申请日：2016-12-11

Applicant: PTC THERAPEUTICS INC

Inventor： BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  MOON YOUNG-CHOON ,  SYDORENKO NADIYA

IPC: C07D403/12 ,  C07D237/20 ,  C07D401/14 ,  C07D403/10 ,  C07D405/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07D471/10 ,  C07D487/10

公开(公告)号：DK3386511T3

公开(公告)日：2021-07-05

申请号：DK16874024

申请日：2016-12-11

Applicant: PTC THERAPEUTICS INC

Inventor： BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  MOON YOUNG-CHOON ,  SYDORENKO NADIYA

IPC: C07D403/12 ,  A61K31/501 ,  A61K31/506 ,  A61K31/517 ,  C07D237/20 ,  C07D401/14 ,  C07D403/10 ,  C07D405/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07D471/10 ,  C07D487/10

公开(公告)号：NZ743147A

公开(公告)日：2021-03-26

申请号：NZ74314716

申请日：2016-12-11

Applicant: PTC THERAPEUTICS INC

Inventor： MOON YOUNG-CHOON ,  BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  SYDORENKO NADIYA

IPC: A61K31/506 ,  A61P25/00 ,  C07D405/12

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington’s disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (Ia), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington’s disease.

公开(公告)号：AU2016366694C1

公开(公告)日：2021-03-25

申请号：AU2016366694

申请日：2016-12-11

Applicant: PTC THERAPEUTICS INC

Inventor： BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  MOON YOUNG-CHOON ,  SYDORENKO NADIYA

IPC: C07D405/12 ,  A61K31/506 ,  A61P25/00

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.