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公开(公告)号：AU2016216569B2
公开(公告)日：2018-01-25
申请号：AU2016216569
申请日：2016-08-16
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO , VERWIJS MARINUS JACOBUS
IPC: A61K47/32
Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3 carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
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12.发明专利
公开(公告)号：CY1118980T1
公开(公告)日：2018-01-10
申请号：CY171100490
申请日：2017-05-05
Applicant: VERTEX PHARMA
Inventor： HURTER PATRICIA , GONG YUCHUAN , YOUNG CHRISTOPHER R , CONNELLY PATRICK , ROWE WILLIAM , COSTACHE ADRIANA , KRAWIEC MARIUSZ , FENG YUSHI , TRUDEAU MARTIN
IPC: C07D215/56 , A61K31/445
Abstract: ΗπαρούσαεφεύρεσηαφοράσεστερεάςκατάστασηςμορφέςτουΝ-[2,4-δις(1,1-διμεθυλαιθυλ)-5-υδροξυφαινυλ]-1,4-διυδρο-4-οξοκινολινο-3-καρβοξαμιδίου (Ένωση 1), φαρμακευτικέςσυνθέσειςαυτούκαιμεθόδουςμεαυτό.
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公开(公告)号：ZA201101097B
公开(公告)日：2012-05-30
申请号：ZA201101097
申请日：2011-02-10
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN C , GROSSI ALFREDO
IPC: A61K20060101
Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
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公开(公告)号：MX2012001939A
公开(公告)日：2012-03-29
申请号：MX2012001939
申请日：2010-02-18
Applicant: VERTEX PHARMA
Inventor： GROOTENHUIS PETER D J , ZLOKARNIK GREGOR , HURTER PATRICIA , GROSSI ALFREDO , ROWE WILLIAM , DINEHART KIRK , OVERHOFF KIRK , BOTFIELD MARTYN , VERWIJS MARINUS JACOBUS , GOOR FREDRICK F VAN , YOUNG CHRISTOPHER R
Abstract: La presente invención se relaciona con composiciones farmacéuticas que comprenden una dispersión sólida de N-[2,4-Bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-dihidro-4-oxoquin olina-3-carboxamida, los métodos para elaborar las composiciones farmacéuticas de la presente invención, y los métodos para administrar las composiciones farmacéuticas de la presente invención.
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公开(公告)号：AU2009282419A1
公开(公告)日：2010-02-18
申请号：AU2009282419
申请日：2009-08-13
Applicant: VERTEX PHARMA
Inventor： ROWE WILLIAM , HURTER PATRICIA , YOUNG CHRISTOPHER , DINEHART KIRK , VERWIJS MARINUS JACOBUS , OVERHOFF KIRK , GROOTENHUIS PETER D J , BOTFIELD MARTYN , GROSSI ALFREDO
IPC: A61K47/32
Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
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Patent Agency Ranking
公开(公告)号：ES2718273T5
公开(公告)日：2025-02-06
申请号：ES10708442
申请日：2010-02-18
Applicant: VERTEX PHARMA
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17.发明专利
公开(公告)号：AU2020201314B2
公开(公告)日：2022-02-03
申请号：AU2020201314
申请日：2020-02-21
Applicant: VERTEX PHARMA
Inventor： HURTER PATRICIA , CONNELLY PATRICK , ROWE WILLIAM , YOUNG CHRISTOPHER R , COSTACHE ADRIANA , KRAWIEC MARIUSZ , GONG YUCHUAN , FENG YUSHI , TRUDEAU MARTIN
IPC: A61K31/445
Abstract: The present invention relates to solid state forms of N-[2,4-bis(1,1-dimethylethyl)-5 hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1), pharmaceutical compositions thereof and methods therewith.
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公开(公告)号：HRP20200708T1
公开(公告)日：2020-07-24
申请号：HRP20200708
申请日：2020-05-04
Applicant: VERTEX PHARMA
Inventor： HURTER PATRICIA , GONG YUCHUAN , YOUNG CHRISTOPHER R , CONNELLY PATRICK , ROWE WILLIAM , COSTACHE ADRIANA , KRAWIEC MARIUSZ , FENG YUSHI , TRUDEAU MARTIN
IPC: C07D215/56 , A61K31/445
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公开(公告)号：ME03356B
公开(公告)日：2019-10-20
申请号：MEP10119
申请日：2010-02-18
Applicant: VERTEX PHARMA
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公开(公告)号：LT2464337T
公开(公告)日：2019-05-10
申请号：LT10708442
申请日：2010-02-18
Applicant: VERTEX PHARMA
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