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公开(公告)号:DE4117371A1
公开(公告)日:1992-12-03
申请号:DE4117371
申请日:1991-05-28
Applicant: BASF AG
Inventor: SAUTER HUBERT DR , LORENZ GISELA DR , STEINER GERD DR , JANSSEN BERND DR , ANKE TIMM PROF DR , STEGLICH WOLFGANG PROF DR
IPC: A61K31/165 , A61K31/215 , A61K31/415 , A61K31/42 , A61K31/44 , A61K31/505
Abstract: Antimycotic compositions containing a compound of the formula in which = Y is =CH-OCH3, =CH-CH3, =CH-CH2-CH3, =CH-SCH3 or =N-OCH3 and X is oxygen, or in which X can also be NH when Y is =N-OCH3, Z is halogen, nitro, cyano, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aralkyl, optionally substituted aryloxyalkyl, optionally substituted arylthioalkyl, optionally substituted heteroarylalkyl, optionally substituted heretoaryloxyalkyl, optionally substituted heteroarylthioalkyl, optionally substituted alkenyl, optionally substituted aralkenyl, optionally substituted aryloxyalkenyl, optionally substituted arylthioalkenyl, optionally substituted heteroarylalkenyl, optionally substituted heteroaryloxyalkenyl, optionally substituted heteroarylthioalkenyl, optionally substituted alkynyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted amino, optionally substituted arylazo, optionally substituted acylamino, OR , SR , SOR , SO2R , -COOR , -CONR R , -COR , -CR =NR , -N=CR R , -CR =N-OR , -CR R -O-N=CR R , and U, V, W are hydrogen or can have one of the meanings stated for Z, or in which two of the groups Z, U, V or W in adjacent positions on the phenyl ring optionally form together an optionally substituted 5- or 6-membered, aromatic or aliphatic ring which is fused onto the phenyl ring and which can optionally contain 1 to 3 hetero atoms (N, S, O), where the groups R to R are optionally identical or different hydrogen, optionally substituted C1-C8-alkyl, optionally substituted C2-C8-alkenyl, optionally substituted C2-C8-alkynyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted aralkyl, optionally substituted heteroarylalkyl, optionally substituted aryloxyalkyl, optionally substituted arylthioalkyl, optionally substituted heteroaryloxyalkyl or optionally substituted heteroarylthioalkyl, and their use for controlling mycoses.
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公开(公告)号:DE4112352A1
公开(公告)日:1992-10-22
申请号:DE4112352
申请日:1991-04-16
Applicant: BASF AG
Inventor: STEINER GERD DR
IPC: C07D211/22 , C07D211/48 , C07D211/52 , C07D211/70 , C07D401/06 , C07D409/14
Abstract: The description relates to novel piperidine derivatives of formula (I) in which R and A-B-D have the meanings given in the description, and their production. The compounds are intermediate products in the manufacture of pharmaceuticals.
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公开(公告)号:DE4041465A1
公开(公告)日:1992-06-25
申请号:DE4041465
申请日:1990-12-22
Applicant: BASF AG
Inventor: STEINER GERD DR , BACH ALFRED DR , UNGER LILIANE DR , RASCHACK MANFRED DR
Abstract: The description relates to the use of 5-cyanomethylene-4-(piperazone-1-yl)-pyrrolo[4,3-e]benzoazepines of formula I, in which R , R and R have the significance given in the specification, for relieving migraine.
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公开(公告)号:DE4041463A1
公开(公告)日:1992-06-25
申请号:DE4041463
申请日:1990-12-22
Applicant: BASF AG
Inventor: STEINER GERD DR , BACH ALFRED DR , UNGER LILIANE DR , RASCHACK MANFRED DR
IPC: C07D295/155
Abstract: The description relates to the use of 5-cyanomethylene-10-(piperazine-1-yl)-dibenzo[a,d]cycloheptenes of formula (I), in which R , R and R have the significance given in the specification, for relieving migraine.
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公开(公告)号:DE3666041D1
公开(公告)日:1989-11-09
申请号:DE3666041
申请日:1986-07-04
Applicant: BASF AG
Inventor: STEINER GERD DR , THYES MARCO DR
IPC: C07D333/00 , C07D409/14 , C07D495/14
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公开(公告)号:AT13885T
公开(公告)日:1985-07-15
申请号:AT81110719
申请日:1981-12-23
Applicant: BASF AG
Inventor: THIEME PETER C DR , STEINER GERD DR , ROHR WOLFGANG DR , LENKE DIETER DR , GRIES JOSEF DR , WEIFENBACH HARALD DR , TESCHENDORF HANS-JUERGEN DR , HOFMANN HANS PETER DR , KREISKOTT HORST DR
IPC: C07D249/08 , A61K31/41 , A61K31/415 , A61K31/495 , A61K31/496 , A61P9/02 , A61P11/00 , A61P25/20 , C07D231/12 , C07D233/60 , C07D233/61 , C07D271/10 , C07D295/06 , C07D295/067 , C07D295/096 , C07D521/00
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27.
公开(公告)号:AT13670T
公开(公告)日:1985-06-15
申请号:AT82102444
申请日:1982-03-24
Applicant: BASF AG
Inventor: STEINER GERD DR , FRIEDRICH LUDWIG DR , LENKE DIETER DR
IPC: A61K31/00 , A61K31/55 , A61P1/04 , C07D223/20 , C07D401/06 , C07D401/12 , C07D403/06 , C07D403/12 , C07D413/12 , C07F9/59
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28.
公开(公告)号:DE3061907D1
公开(公告)日:1983-03-17
申请号:DE3061907
申请日:1980-08-21
Applicant: BASF AG
Inventor: STEINER GERD DR , GRIES JOSEF DR , LENKE DIETER DR
IPC: C07D403/04 , A61K31/50 , A61P9/12 , C07D521/00
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公开(公告)号:HU0004648A2
公开(公告)日:2001-05-28
申请号:HU0004648
申请日:1998-10-05
Applicant: BASF AG
Inventor: BACH ALFRED DR , DULLWEBER UTA , EMLING FRANZ DR , GARCIA-LADONA XAVIER , LUBISCH WILFRIED DR , STARCK DOROTHEA , STEINER GERD DR , TESCHENDORF HANS-JUERGEN DR , WICKE KARSTEN DR
IPC: A61K31/519 , A61P1/00 , A61P1/14 , A61P3/04 , A61P5/00 , A61P9/12 , A61P15/00 , A61P25/00 , A61P25/22 , A61P25/24 , A61P25/28 , A61P43/00 , C07D471/00 , C07D471/04
Abstract: 3-substituted tetrahydropyridopyrimidinone derivatives of the formula (I) wherein the radicals have the meanings given in the Description, to a method for producing said derivatives and, to their use for producing active ingredients for drugs.
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30.
公开(公告)号:CZ287862B6
公开(公告)日:2001-02-14
申请号:CZ31097
申请日:1995-07-21
Applicant: BASF AG
Inventor: STEINER GERD DR , MUNSCHAUER RAINER DR , HOEGER THOMAS DR , UNGER LILIANE DR , TESCHENDORF HANS JUERGEN DR
IPC: C07D401/06 , A61K31/40 , A61K31/415 , A61K31/47 , A61K31/505 , A61P25/18 , A61P43/00 , C07D403/06 , C07D471/04 , C07D513/04 , A61K31/403
Abstract: In the present invention there are disclosed the compounds of the general formula I, in which Re1, Re2, A, X, Y and Z have specific meaning and process of their preparation. The invented novel compounds are suitable for treating diseases of nervous system.
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