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公开(公告)号：SI2332940T1
公开(公告)日：2013-03-29
申请号：SI200531659
申请日：2005-03-30
Applicant: VERTEX PHARMA
Inventor： SALITURO FRANCESCO , FARMER LUC , BETHIEL RANDY , HARRINGTON EDMUND , GREEN JEREMY , COURT JOHN , COME JON , LAUFFER DAVID , ARONOV ALEX , BINCH HAYLEY , BOYALL DEAN , CHARRIER JEAN-DAMIEN , EVERITT SIMON , FRAYSSE DAMIEN , MORTIMORE MICHAEL , PIERARD FRANCOISE , ROBINSON DANIEL , PINDER JOANNE , WANG TIANSHENG , PIERCE ALBERT , WANG JIAN
IPC: C07D471/00 , C07D519/00
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公开(公告)号：AU2005228904C1
公开(公告)日：2012-12-13
申请号：AU2005228904
申请日：2005-03-30
Applicant: VERTEX PHARMA
Inventor： COURT JOHN , ROBINSON DANIEL , CHARRIER JEAN-DAMIEN , FRAYSSE DAMIEN , MORTIMORE MICHAEL , LAUFFER DAVID , BETHIEL RANDY , FARMER LUC , HARRINGTON EDMUND , COME JON , GREEN JEREMY , EVERITT SIMON , BINCH HAYLEY , SALITURO FRANCESCO , PIERARD FRANCOISE , ARONOV ALEX , BOYALL DEAN , WANG JIAN , PINDER JOANNE , WANG TIANSHENG , PIERCE ALBERT
IPC: C07D471/04 , C07D519/00
Abstract: The present invention relates to compounds of formula (I), which are inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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公开(公告)号：AU2005228904B8
公开(公告)日：2012-08-02
申请号：AU2005228904
申请日：2005-03-30
Applicant: VERTEX PHARMA
Inventor： COURT JOHN , ROBINSON DANIEL , CHARRIER JEAN-DAMIEN , FRAYSSE DAMIEN , MORTIMORE MICHAEL , LAUFFER DAVID , BETHIEL RANDY , FARMER LUC , HARRINGTON EDMUND , COME JON , GREEN JEREMY , EVERITT SIMON , BINCH HAYLEY , SALITURO FRANCESCO , PIERARD FRANCOISE , ARONOV ALEX , BOYALL DEAN , WANG JIAN , PINDER JOANNE , WANG TIANSHEN , PIERCE ALBERT
IPC: C07D471/04 , C07D519/00
Abstract: The present invention relates to compounds of formula (I), which are inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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公开(公告)号：AU2005228904B2
公开(公告)日：2012-05-10
申请号：AU2005228904
申请日：2005-03-30
Applicant: VERTEX PHARMA
Inventor： COURT JOHN , ROBINSON DANIEL , CHARRIER JEAN-DAMIEN , FRAYSSE DAMIEN , MORTIMORE MICHAEL , LAUFFER DAVID , BETHIEL RANDY , FARMER LUC , HARRINGTON EDMUND , COME JON , GREEN JEREMY , EVERITT SIMON , BINCH HAYLEY , SALITURO FRANCESCO , PIERARD FRANCOISE , ARONOV ALEX , BOYALL DEAN
IPC: C07D471/04 , C07D519/00
Abstract: The present invention relates to compounds of formula (I), which are inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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公开(公告)号：RS51830B
公开(公告)日：2012-02-29
申请号：RSP20110341
申请日：2005-03-30
Applicant: VERTEX PHARMA
Inventor： SALITURO FRANCESCO , FARMER LUC , BETHIEL RANDY , HARRINGTON EDMUND , GREEN JEREMY , COURT JOHN , COME JON , LAUFFER DAVID , ARONOV ALEX , BINCH HAYLEY , BOYALL DEAN , CHARRIER JEAN-DAMIEN , EVERITT SIMON , FRAYSSE DAMIEN , MORTIMORE MICHAEL , PIERARD FRANCOISE , ROBINSON DANIEL , PINDER JOANNE , WANG TIANSHENG , PIERCE ALBERT
IPC: C07D471/04 , C07D519/00
Abstract: The present invention relates to compounds of formula (I), which are inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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Patent Agency Ranking
公开(公告)号：SI1730146T1
公开(公告)日：2011-09-30
申请号：SI200531340
申请日：2005-03-30
Applicant: VERTEX PHARMA
Inventor： SALITURO FRANCESCO , FARMER LUC , BETHIEL RANDY , HARRINGTON EDMUND , GREEN JEREMY , COURT JOHN , COME JON , LAUFFER DAVID , ARONOV ALEX , BINCH HAYLEY , BOYALL DEAN , CHARRIER JEAN-DAMIEN , EVERITT SIMON , FRAYSSE DAMIEN , MORTIMORE MICHAEL , PIERARD FRANCOISE , ROBINSON DANIEL , PINDER JOANNE , WANG TIANSHENG , PIERCE ALBERT
IPC: C07D471/00 , C07D471/04 , C07D519/00
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公开(公告)号：DK1730146T3
公开(公告)日：2011-08-15
申请号：DK05756052
申请日：2005-03-30
Applicant: VERTEX PHARMA
Inventor： GREEN JEREMY , COURT JOHN , PINDER JOANNE , WANG TIANSHENG , SALITURO FRANCESCO , FARMER LUC , BETHIEL RANDY , HARRINGTON EDMUND , COME JON , LAUFFER DAVID , ARONOV ALEX , BINCH HAYLEY , BOYALL DEAN , CHARRIER JEAN-DAMIEN , EVERITT SIMON , FRAYSSE DAMIEN , MORTIMORE MICHAEL , PIERARD FRANCOISE , ROBINSON DANIEL , PIERCE ALBERT
IPC: C07D471/04 , C07D519/00
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公开(公告)号：HK1142882A1
公开(公告)日：2010-12-17
申请号：HK10108367
申请日：2010-10-11
Applicant: VERTEX PHARMA
Inventor： SALITURO FRANCESCO , FARMER LUC , BETHIEL RANDY , HARRINGTON EDMUND , GREEN JEREMY , COURT JOHN , COME JON , LAUFFER DAVID , ARONOV ALEX , BINCH HAYLEY , BOYALL DEAN , CHARRIER JEAN-DAMIEN J , EVERITT SIMON , FRAYSSE DAMIEN , MORTIMORE MICHAEL , PIERARD FRANCOISE , ROBINSON DANIEL , WANG JIAN , PINDER JOANNE , WANG TIANSHENG , PIERCE ALBERT
IPC: C07D20060101 , A61K20060101 , A61P20060101 , C07D471/04 , C07D519/00
Abstract: The present invention relates to compounds of formula (I), which are inhibitors of protein kinases. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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公开(公告)号：NZ549880A
公开(公告)日：2010-04-30
申请号：NZ54988005
申请日：2005-03-30
Applicant: VERTEX PHARMA
Inventor： SALITURO FRANCESCO , FARMER LUC , BETHIEL RANDY , HARRINGTON EDMUND , GREEN JEREMY , COURT JOHN , COME JON , LAUFFER DAVID , ARONOV ALEX , BINCH HAYLEY , BOYALL DEAN , CHARRIER JEAN-DAMIEN , EVERITT SIMON , FRAYSSE DAMIEN , MORTIMORE MICHAEL , PIERARD FRANCOISE , ROBINSON DANIEL , WANG JIAN , PINDER JOANNE , WANG TIANSHENG , PIERCE ALBERT
IPC: C07D471/04 , C07D519/00
Abstract: Disclosed is a compound of formula (IB) or pharmaceutically acceptable salts thereof wherein the substituents are disclosed within the specification. Also disclosed is the use of a compound of formula (IB) in the manufacture of a medicament for inhibiting JAK-3, ROCK or Aurora kinase activity.
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公开(公告)号：CA2663528A1
公开(公告)日：2008-03-27
申请号：CA2663528
申请日：2007-09-18
Applicant: VERTEX PHARMA
Inventor： TANNER KIRK , NANTHAKUMAR SUGANTHINI , COME JON , ARONOV ALEXANDER , MCGINTY KIRA , LI PAN , COURT JOHN , DEININGER DAVID , STAMOS DEAN , LAUFFER DAVID
IPC: C07D497/04 , A61K31/433 , A61P35/00 , C07D513/04
Abstract: The present invention provides compounds useful as inhibitors of c-Met ty rosine kinase. The invention also provides pharmaceutically acceptable compo sitions comprising the compounds of the invention and methods of using the c ompositions in the treatment of various proliferative disorders.
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