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公开(公告)号：CA2709961A1
公开(公告)日：2009-07-09
申请号：CA2709961
申请日：2008-12-18
Applicant: ABBOTT LAB
Inventor： BLACK LAWRENCE A , COWART MARLON D , GFESSER GREGORY A , WAKEFIELD BRIAN D , ALTENBACH ROBERT J , LIU HUAQING , ZHAO CHEN , HSIEH GIN C
IPC: A61K31/423 , A61K31/428 , A61P3/10 , A61P25/00 , C07D413/14 , C07D417/14
Abstract: Compounds of formula (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions of compounds of formula (I), methods for using such compounds and compositions, and a process for preparing the compounds.
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公开(公告)号：MX2008016338A
公开(公告)日：2009-01-16
申请号：MX2008016338
申请日：2007-06-27
Applicant: ABBOTT LAB
Inventor： FAGHIH RAMIN , GFESSER GREGORY A , LYNCH CHRISTOPHER L , GOPALAKRISHNAN MURALI , GOPALAKRISHNAN SUJATHA , MALYSZ JOHN , GUBBINS EARL J , KOUHEN RACHID EL , LI JINHE
IPC: C07D207/34 , A61K31/402 , A61K31/56 , A61K31/58 , A61P25/00 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07J9/00
Abstract: La invención se refiere a una serie de derivados de pirrol substituido, composiciones que comprenden los mismos, y métodos para tratar condiciones o trastornos utilizando dichos compuestos y composiciones.
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公开(公告)号：CA2659762A1
公开(公告)日：2008-01-03
申请号：CA2659762
申请日：2007-06-27
Applicant: ABBOTT LAB
Inventor： GOPALAKRISHNAN SUJATHA , EL KOUHEN RACHID , SARRIS KATHY A , LI JINHE , MALYSZ JOHN , GUBBINS EARL J , GOPALAKRISHNAN MURALI , WANG YING , MICHMERHUIZEN MELISSA J , LYNCH CHRISTOPHER L , GFESSER GREGORY A , FAGHIH RAMIN
IPC: C07D417/04 , A61K31/422 , A61K31/427 , C07D413/04 , C07D417/14
Abstract: The invention relates to compounds of formula I selected from compounds. The compounds of formula (I) in treating conditions and disorders that are r egulated by the nicotinic acetylcholine receptors.
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公开(公告)号：AU2007265116A1
公开(公告)日：2008-01-03
申请号：AU2007265116
申请日：2007-06-27
Applicant: ABBOTT LAB
Inventor： GOPALAKRISHNAN SUJATHA , LI JINHE , GUBBINS EARL J , GOPALAKRISHNAN MURALI , GFESSER GREGORY A , FAGHIH RAMIN , MALYSZ JOHN , LYNCH CHRISTOPHER L , KOUHEN RACHID EL
IPC: C07D207/34 , A61K31/402 , A61P25/00 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10
Abstract: The invention relates to a series of substituted pyrrole derivatives, compositions comprising the same, and methods of treating conditions and disorders using such compounds and compositions.
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公开(公告)号：MXPA06013198A
公开(公告)日：2007-02-28
申请号：MXPA06013198
申请日：2005-04-29
Applicant: ABBOTT LAB
Inventor： CHANG SOU-JEN , KU YI-YIN , ALTENBACH ROBERT J , BLACK LAWRENCE A , COWART MARLON D , FAGHIH RAMIN , GFESSER GREGORY A , LIU HUAQING , LUKIN KIRILL A , NERSESIAN DIANA L , PU YU-MING , CURTIS MICHAEL P
IPC: A61K31/4725 , C07D401/00 , C07D401/14 , C07D405/14 , C07D409/14 , C07D471/02 , C07D471/04 , C07D487/04 , C07D491/02 , C07D491/04 , C07D495/04 , C07D498/02 , C07D513/04
Abstract: Ver formula (I): Los compuestos de la formula (I) en la cual R1 o R2 es un anillo triciclico o biciclico, cada uno de los cuales contienen cuando menos dos heteroatomos, y R1, R2, R3, R3a, R3b, L.X, X', Y, Y'.X y Z son como se definen aqui, son utiles para tratar condiciones o enfermedades que pueden prevenirse o tratarse por medio de los ligantes del receptor de histamina-3. Tambien se describen composiciones farmaceuticas que contienen ligantes del receptor de histamina-3, metodo para usar esos compuestos y composiciones, y un proceso para preparar compuestos dentro del alcance de la formula (I).
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Patent Agency Ranking36.发明专利
公开(公告)号：MXPA06013197A
公开(公告)日：2007-02-28
申请号：MXPA06013197
申请日：2005-04-29
Applicant: ABBOTT LAB
Inventor： KU YI-YIN , ALTENBACH ROBERT J , BLACK LAWRENCE A , COWART MARLON D , FAGHIH RAMIN , GFESSER GREGORY A , LIU HUAQING , LUKIN KIRILL A , NERSESIAN DIANA L , PU YU-MING , CURTIS MICHAEL P , CHANG SOU-JEN
IPC: C07D417/14 , A61K31/00 , A61K31/4709 , A61P25/28 , C07D215/12 , C07D401/04 , C07D401/08 , C07D401/14 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04
Abstract: Ver formula (I): Los compuestos de la formula (I) en los cuales R1 o R2 es un anillo aromatico o no aromatico que esta unido directamente o a traves de un enlace, representado por L2 y L3, al nucleo heteroaromatico, y X, X', Y, Y', Z, Z', R1, R2, R3, R3a, R3b, L, L2 y L3 son como se definen aqui, son utiles para tratar condiciones o enfermedades que se pueden prevenir o aliviar por medio de ligantes de receptores de histamina-3. Tambien se describen composiciones farmaceuticas que contienen ligantes del receptor de histamina-3, metodo para usar esos compuestos y composiciones, y un proceso para preparar compuestos dentro del alcance de la formula (I).
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公开(公告)号：PL376751A1
公开(公告)日：2006-01-09
申请号：PL37675103
申请日：2003-11-05
Applicant: ABBOTT LAB
Inventor： ALTENBACH ROBERT J , BLACK LAWRENCE A , CHANG SOU-JEN , COWART MARLON D , FAGHIH RAMIN , GFESSER GREGORY A , KU YI-YIN , LIU HUAQING , LUKIN KIRILL A , NERSESIAN DIANA L , PU YU-MING , SHARMA PADAM N , BENNANI YOUSSEF L , CURTIS MICHAEL P
IPC: C07D295/155 , A61K31/40 , A61P3/00 , A61P25/00 , C07C255/58 , C07D207/08 , C07D207/12 , C07D207/14 , C07D207/20 , C07D213/30 , C07D213/38 , C07D213/61 , C07D213/64 , C07D213/85 , C07D215/12 , C07D215/14 , C07D215/20 , C07D217/14 , C07D237/12 , C07D237/14 , C07D237/28 , C07D239/26 , C07D239/28 , C07D239/42 , C07D239/52 , C07D241/12 , C07D241/42 , C07D263/32 , C07D277/28 , C07D295/073 , C07D295/092 , C07D295/096 , C07D295/112 , C07D295/135 , C07D401/04 , C07D401/10 , C07D403/04 , C07D403/10 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D471/04
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公开(公告)号：CA2566896A1
公开(公告)日：2005-12-01
申请号：CA2566896
申请日：2005-04-29
Applicant: ABBOTT LAB
Inventor： NERSESIAN DIANA L , FAGHIH RAMIN , PU YU-MING , ALTENBACH ROBERT J , CURTIS MICHAEL P , COWART MARLON D , BLACK LAWRENCE A , CHANG SOU-JEN , LIU HUAQING , KU YI-YIN , LUKIN KIRILL A , GFESSER GREGORY A
IPC: C07D417/14 , A61K31/4709 , A61P25/00 , A61P25/28 , C07D215/12 , C07D401/04 , C07D401/08 , C07D401/14 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04
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公开(公告)号：BR0205829A
公开(公告)日：2005-03-08
申请号：BR0205829
申请日：2002-03-11
Applicant: ABBOTT LAB
Inventor： COWART MARLON D , BENNANI YOUSSEF L , FAGHIH RAMIN , GFESSER GREGORY A , BLACK LAWRENCE A
IPC: A61K31/343 , A61K31/4025 , A61K31/4245 , A61K31/427 , A61K31/437 , A61K31/4439 , A61K31/5377 , A61K31/55 , A61P1/00 , A61P1/08 , A61P3/04 , A61P7/08 , A61P9/00 , A61P9/10 , A61P11/02 , A61P11/06 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P25/30 , A61P29/00 , A61P31/04 , A61P35/00 , A61P43/00 , C07D307/79 , C07D307/81 , C07D311/18 , C07D333/54 , C07D405/04 , C07D405/06 , C07D405/14 , C07D407/04 , C07D409/04 , C07D409/10 , C07D409/14 , C07D413/04 , C07D413/14 , C07D417/04 , C07D417/14 , C07D471/04 , C07D491/08 , C07D491/10 , C07D521/00 , A61K31/4427
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公开(公告)号：CA2765093A1
公开(公告)日：2004-05-27
申请号：CA2765093
申请日：2003-11-05
Applicant: ABBOTT LAB
Inventor： ALTENBACH ROBERT J , BLACK LAWRENCE A , CHANG SOU-JEN , COWART MARLON D , FAGHIH RAMIN , GFESSER GREGORY A , KU YI-YIN , LIU HUAQING , LUKIN KIRILL A , NERSESIAN DIANA L , PU YU-MING , SHARMA PADAM N , BENNANI YOUSSEF L , CURTIS MICHAEL P
IPC: C07D401/00 , A61K31/40 , A61K31/427 , A61K31/4439 , A61K31/445 , A61K31/465 , A61K31/501 , A61K31/502 , A61K31/506 , A61K31/5377 , A61K31/541 , A61P3/00 , A61P25/00 , C07C255/58 , C07D207/04 , C07D207/08 , C07D207/12 , C07D207/14 , C07D207/20 , C07D213/30 , C07D213/38 , C07D213/61 , C07D213/64 , C07D213/85 , C07D215/12 , C07D215/14 , C07D215/20 , C07D217/14 , C07D237/12 , C07D237/14 , C07D237/28 , C07D239/26 , C07D239/28 , C07D239/42 , C07D239/52 , C07D241/12 , C07D241/42 , C07D263/32 , C07D277/28 , C07D295/073 , C07D295/092 , C07D295/096 , C07D295/112 , C07D295/135 , C07D295/155 , C07D401/04 , C07D401/10 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/10 , C07D405/04 , C07D409/04 , C07D413/04 , C07D417/04 , C07D471/04
Abstract: Compounds of forumla (I) are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositins, and a process for preparing compounds within the scope of formula (I).
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